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Items: 1 to 20 of 230

1.
Inhibiting AGTR1 reduces AML burden and protects the heart from cardiotoxicity in mouse models
Yi Pan, Chen Wang, WenXuan Zhou, Yao Shi, XiaDuo Meng, Yasir Muhammad, Richard D. Hammer, Bei Jia, Hong Zheng, De-Pei Li, Zhenguo Liu, Gerhard Hildebrandt, XunLei Kang
Sci Transl Med. Author manuscript; available in PMC 2024 Jul 16.
Published in final edited form as: Sci Transl Med. 2024 Jun 19; 16(752): eadl5931. Published online 2024 Jun 19. doi: 10.1126/scitranslmed.adl5931
PMCID:
PMC11250918
AbstractArticlePDF–3.3M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia
Simon Vermeiren, Pauline Cabochette, Maya Dannawi, Simon Desiderio, Alba Sabaté San José, Younes Achouri, Sadia Kricha, Maren Sitte, Gabriela Salinas-Riester, Benoit Vanhollebeke, Jean-François Brunet, Eric J. Bellefroid
iScience. 2023 Dec 15; 26(12): 108364. Published online 2023 Oct 31. doi: 10.1016/j.isci.2023.108364
PMCID:
PMC10663820
AbstractArticlePDF–5.8M
4.
Angiotensin AT1A receptor signal switching in Agouti-related peptide neurons mediates metabolic rate adaptation during obesity
Kirthikaa Balapattabi, Yavuz Yavuz, Jingwei Jiang, Guorui Deng, Natalia M. Mathieu, McKenzie L. Ritter, Megan A. Opichka, John J. Reho, John D. McCorvy, Pablo Nakagawa, Lisa L. Morselli, Gary C. Mouradian, Jr., Deniz Atasoy, Huxing Cui, Matthew R. Hodges, Curt D. Sigmund, Justin L. Grobe
Cell Rep. Author manuscript; available in PMC 2023 Sep 27.
Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112935. Published online 2023 Aug 2. doi: 10.1016/j.celrep.2023.112935
PMCID:
PMC10530419
AbstractArticlePDF–2.5M
5.
Intracellular Angiotensin II Stimulation of Sodium Transporter Expression in Proximal Tubule Cells via AT1 (AT1a) Receptor-Mediated, MAP Kinases ERK1/2- and NF-кB-Dependent Signaling Pathways
Xiaochun Li, Jialong Zhuo
Cells. 2023 Jun; 12(11): 1492. Published online 2023 May 28. doi: 10.3390/cells12111492
PMCID:
PMC10252550
AbstractArticlePDF–8.7M
6.
Angiotensin II type 1a receptor deficiency alleviates muscle atrophy after denervation
Suguru Takayama, Kazuho Inoue, Yuji Ogura, Seiko Hoshino, Takeshi Sugaya, Keiichi Ohata, Hitoshi Kotake, Daisuke Ichikawa, Minoru Watanabe, Kenjiro Kimura, Yugo Shibagaki, Atsuko Kamijo-Ikemori
Sci Rep. 2023; 13: 519. Published online 2023 Jan 10. doi: 10.1038/s41598-023-27737-7
PMCID:
PMC9832142
AbstractArticlePDF–4.9M
7.
Genetic Deletion of AT1a Receptor or Na+/H+ Exchanger 3 Selectively in the Proximal Tubules of the Kidney Attenuates Two-Kidney, One-Clip Goldblatt Hypertension in Mice
Xiao Chun Li, Rumana Hassan, Ana Paula O. Leite, Akemi Katsurada, Courtney Dugas, Ryosuke Sato, Jia Long Zhuo
Int J Mol Sci. 2022 Dec; 23(24): 15798. Published online 2022 Dec 13. doi: 10.3390/ijms232415798
PMCID:
PMC9779213
AbstractArticlePDF–3.6M
8.
Neuroendocrinology of the lung revealed by single-cell RNA sequencing
Christin S Kuo, Spyros Darmanis, Alex Diaz de Arce, Yin Liu, Nicole Almanzar, Timothy Ting-Hsuan Wu, Stephen R Quake, Mark A Krasnow
eLife. 2022; 11: e78216. Published online 2022 Dec 5. doi: 10.7554/eLife.78216
PMCID:
PMC9721618
AbstractArticlePDF–6.7M
9.
Cardiometabolic Consequences of Deleting the Regulator of G protein Signaling-2 (Rgs2) from Cells Expressing Agouti-Related Peptide or the Angiotensin II Type 1A Receptor in Mice
McKenzie L. Ritter, Guorui Deng, John J. Reho, Yue Deng, Sarah A. Sapouckey, Megan A. Opichka, Kirthikaa Balapattabi, Kelsey K. Wackman, Daniel T. Brozoski, Ko-Ting Lu, William J. Paradee, Katherine N. Gibson-Corley, Huxing Cui, Pablo Nakagawa, Lisa L. Morselli, Curt D. Sigmund, Justin L. Grobe
Hypertension. Author manuscript; available in PMC 2023 Dec 1.
Published in final edited form as: Hypertension. 2022 Dec; 79(12): 2843–2853. Published online 2022 Oct 19. doi: 10.1161/HYPERTENSIONAHA.122.20169
PMCID:
PMC9649888
AbstractArticlePDF–1.1M
10.
A brainstem circuit for nausea suppression
Chuchu Zhang, Lindsay K. Vincelette, Frank Reimann, Stephen D. Liberles
Cell Rep. Author manuscript; available in PMC 2022 Jul 7.
Published in final edited form as: Cell Rep. 2022 Jun 14; 39(11): 110953. doi: 10.1016/j.celrep.2022.110953
PMCID:
PMC9260880
AbstractArticlePDF–2.2M
11.
Sex differences in angiotensin II-induced hypertension and kidney injury: role of AT1a receptors in the proximal tubule of the kidney
Ana Paula Oliveira Leite, Xiao C. Li, Rumana Hassan, Xiaowen Zheng, Barbara Alexander, Dulce Elena Casarini, Jia L. Zhuo
Clin Sci (Lond) Author manuscript; available in PMC 2022 Aug 13.
Published in final edited form as: Clin Sci (Lond). 2021 Aug 13; 135(15): 1825–1843. doi: 10.1042/CS20201574
PMCID:
PMC8969897
AbstractArticlePDF–3.8M
12.
A multidimensional coding architecture of the vagal interoceptive system
Qiancheng Zhao, Chuyue D. Yu, Rui Wang, Qian J. Xu, Rafael Dai Pra, Le Zhang, Rui B. Chang
Nature. 2022; 603(7903): 878–884. Published online 2022 Mar 16. doi: 10.1038/s41586-022-04515-5
PMCID:
PMC8967724
AbstractArticlePDF–37M
13.
Angiotensin II enhances group 2 innate lymphoid cell responses via AT1a during airway inflammation
Gaoyu Liu, Yingying Chen, Ying Wang, Xiaohui Deng, Qiang Xiao, Lijuan Zhang, Haixu Xu, Xu Han, Aihua Lei, Juan He, Xing Li, Yingjiao Cao, Pan Zhou, Chunhui He, Peiqiong Wu, Wenhui Jiang, Meizheng Tan, Chun Chen, Quan Yang, Liwei Lu, Kai Deng, Zhi Yao, Jie Zhou
J Exp Med. 2022 Mar 7; 219(3): e20211001. Published online 2022 Jan 19. doi: 10.1084/jem.20211001
PMCID:
PMC8932533
AbstractArticlePDF–10M
14.
Embryonic osteocalcin signaling determines lifelong adrenal steroidogenesis and homeostasis in the mouse
Vijay K. Yadav, Julian M. Berger, Parminder Singh, Perumal Nagarajan, Gerard Karsenty
J Clin Invest. 2022 Feb 15; 132(4): e153752. Published online 2022 Feb 15. doi: 10.1172/JCI153752
PMCID:
PMC8843753
AbstractArticlePDF–4.9M
15.
Generation of the organotypic kidney structure by integrating pluripotent stem cell-derived renal stroma
Shunsuke Tanigawa, Etsuko Tanaka, Koichiro Miike, Tomoko Ohmori, Daisuke Inoue, Chen-Leng Cai, Atsuhiro Taguchi, Akio Kobayashi, Ryuichi Nishinakamura
Nat Commun. 2022; 13: 611. Published online 2022 Feb 1. doi: 10.1038/s41467-022-28226-7
Correction in:
Nat Commun. 2023; 14: 1874.
PMCID:
PMC8807595
AbstractArticlePDF–5.4M
16.
Angiotensin II receptor 1 controls profibrotic Wnt/β-catenin signalling in experimental autoimmune myocarditis
Marcin Czepiel, Dario Diviani, Agnieszka Jaźwa-Kusior, Karolina Tkacz, Filip Rolski, Ryszard T Smolenski, Maciej Siedlar, Urs Eriksson, Gabriela Kania, Przemysław Błyszczuk
Cardiovasc Res. 2022 Feb; 118(2): 573–584. Published online 2021 Feb 8. doi: 10.1093/cvr/cvab039
PMCID:
PMC8803091
AbstractArticlePDF–2.0M
17.
The Receptor AT1 Appears to Be Important for the Maintenance of Bone Mass and AT2 Receptor Function in Periodontal Bone Loss Appears to Be Regulated by AT1 Receptor
Maria Laura de Souza Lima, Agnes Andrade Martins, Caroline Addison Carvalho Xavier de Medeiros, Gerlane Coelho Bernardo Guerra, Robson Santos, Michael Bader, Flavia Q. Pirih, Raimundo Fernandes de Araújo Júnior, Gerly Anne de Castro Brito, Renata Ferreira de Carvalho Leitão, Rafaela Alcindo Silva, Stphannie Jamyla de Araújo Barbosa, Rômulo Camilo de Oliveira Melo, Aurigena Antunes de Araújo
Int J Mol Sci. 2021 Dec; 22(23): 12849. Published online 2021 Nov 27. doi: 10.3390/ijms222312849
PMCID:
PMC8657877
AbstractArticlePDF–3.4M
18.
Increased AT1 Receptor Expression and Its Mediated Vasoconstriction Lead to Hypertension in Snx1−/− Mice
Chao Liu, Xingyue Li, Jinjuan Fu, Ken Chen, Qiao Liao, Jialiang Wang, Caiyu Chen, Hao Luo, Pedro A. Jose, Yongjian Yang, Jian Yang, Chunyu Zeng
Hypertens Res. Author manuscript; available in PMC 2021 Nov 13.
Published in final edited form as: Hypertens Res. 2021 Aug; 44(8): 906–917. Published online 2021 May 10. doi: 10.1038/s41440-021-00661-x
PMCID:
PMC8590203
AbstractArticlePDF–1.0M
19.
Stearoyl-CoA Desaturase (SCD) Induces Cardiac Dysfunction with Cardiac Lipid Overload and Angiotensin II AT1 Receptor Protein Up-Regulation
Joshua Abd Alla, Yahya F. Jamous, Ursula Quitterer
Int J Mol Sci. 2021 Sep; 22(18): 9883. Published online 2021 Sep 13. doi: 10.3390/ijms22189883
PMCID:
PMC8472087
AbstractArticlePDF–11M
20.
Deletion of AT1a Receptor or Inhibition of Angiotensinogen Synthesis Attenuates Thoracic Aortopathies in Fibrillin1C1041G/+ Mice
Jeff Z. Chen, Hisashi Sawada, Dien Ye, Yuriko Katsumata, Masayoshi Kukida, Satoko Ohno-Urabe, Jessica J. Moorleghen, Michael K. Franklin, Deborah A. Howatt, Mary B. Sheppard, Adam E. Mullick, Hong S. Lu, Alan Daugherty
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2022 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2021 Oct; 41(10): 2538–2550. Published online 2021 Aug 19. doi: 10.1161/ATVBAHA.121.315715
PMCID:
PMC8458261
AbstractArticlePDF–2.3M

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