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Select item 115650401.

Single-cell RNA transcriptomics in mice reveals embryonic origin of fibrosis due to maternal obesity

Md Nazmul Hossain, Yao Gao, Xinrui Li, Liang Zhao, Xiangdong Liu, Jeanene Marie de Avila, Mei-Jun Zhu, Min Du

eBioMedicine. 2024 Nov; 109: 105421. Published online 2024 Oct 30. doi: 10.1016/j.ebiom.2024.105421

PMCID:: PMC11565040

Abstract Article PDF–4.9M

Select item 113659542.

Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation

Vaishali N. Patel, Marit H. Aure, Sophie H. Choi, James R. Ball, Ethan D. Lane, Zhangjie Wang, Yongmei Xu, Changyu Zheng, Xibao Liu, Daniel Martin, Jillian Y. Pailin, Michaela Prochazkova, Ashok B. Kulkarni, Toin H. van Kuppevelt, Indu S. Ambudkar, Jian Liu, Matthew P. Hoffman

Nat Commun. 2024; 15: 7584. Published online 2024 Aug 31. doi: 10.1038/s41467-024-51862-0

Correction in:: Nat Commun. 2024; 15: 8784.

PMCID:: PMC11365954

Abstract Article PDF–5.0M

Select item 112876363.

ZFYVE19 deficiency: a ciliopathy involving failure of cell division, with cell death

Jing Yang, Ya-Nan Zhang, Ren-Xue Wang, Chen-Zhi Hao, Yiling Qiu, Hao Chi, Wei-Sha Luan, HongYi Tang, Xiu-Juan Zhang, XuXu Sun, Jonathan A Sheps, Victor Ling, Muqing Cao, Jian-she Wang

J Med Genet. 2024 Aug; 61(8): 750–758. Published online 2024 May 30. doi: 10.1136/jmg-2023-109779

PMCID:: PMC11287636

Abstract Article PDF–6.1M

Select item 107838464.

miRNA-660-3p inhibits malignancy in glioblastoma via negative regulation of APOC1-TGFβ2 signaling pathway

Zelin Yang, Liang Yang, Zhenkai Sun, Yuxi Rong, Chenglian Bai, Qiaoxiang Dong, Lin Jian

Cancer Biol Ther. 2023; 24(1): 2281459. Published online 2023 Nov 19. doi: 10.1080/15384047.2023.2281459

PMCID:: PMC10783846

Abstract Article PDF–5.2M

Select item 107061485.

The Research Progress in Transforming Growth Factor-β2

Meng-Yan Wang, Wen-Juan Liu, Le-Yi Wu, Gang Wang, Cheng-Lin Zhang, Jie Liu

Cells. 2023 Dec; 12(23): 2739. Published online 2023 Nov 30. doi: 10.3390/cells12232739

PMCID:: PMC10706148

Abstract Article PDF–3.8M

Select item 106629726.

Myocardial equation M1

-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation

Yidong Wang, Pengfei Lu, Bingruo Wu, Dario F. Riascos-Bernal, Nicholas E.S. Sibinga, Tomas Valenta, Konrad Basler, Bin Zhou

J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Nov 21.

Published in final edited form as: J Mol Cell Cardiol. 2018 Oct; 123: 150–158. Published online 2018 Sep 8. doi: 10.1016/j.yjmcc.2018.09.001

PMCID:: PMC10662972

Abstract Article PDF–2.2M

Select item 106559187.

The transcription factors Foxf1 and Foxf2 integrate the SHH, HGF and TGFβ signaling pathways to drive tongue organogenesis

Jingyue Xu, Han Liu, Yu Lan, Rulang Jiang

Development. 2022 Nov 1; 149(21): dev200667. Published online 2022 Oct 28. doi: 10.1242/dev.200667

PMCID:: PMC10655918

Abstract Article

Select item 105277638.

TGFβ−2 haploinsufficiency causes early death in mice with Marfan syndrome

Nalani Sachan, Colin K.L. Phoon, Lior Zilberberg, Matthias C. Kugler, Taylor Ene, Shana B. Mintz, Sae-Il Murtada, Dar Weiss, Glenn I. Fishman, Jay D. Humphrey, Daniel B. Rifkin

Matrix Biol. Author manuscript; available in PMC 2023 Sep 27.

Published in final edited form as: Matrix Biol. 2023 Aug; 121: 41–55. Published online 2023 May 20. doi: 10.1016/j.matbio.2023.05.004

PMCID:: PMC10527763

Abstract Article PDF–1.6M

Select item 104107539.

Elevated TGFβ signaling contributes to ocular anterior segment dysgenesis in Col4a1 mutant mice

Mao Mao, Cassandre Labelle-Dumais, Sara F. Tufa, Douglas R. Keene, Douglas B. Gould

Matrix Biol. Author manuscript; available in PMC 2023 Aug 9.

Published in final edited form as: Matrix Biol. 2022 Jun; 110: 151–173. Published online 2022 May 4. doi: 10.1016/j.matbio.2022.05.001

PMCID:: PMC10410753

Abstract Article PDF–2.2M

Select item 1025951410.

Dysfunction of programmed embryo senescence is linked to genetic developmental defects

Cristina de Lope, Rebeca García-Lucena, Marta Magariños, Yolanda León, Nuria Casa-Rodríguez, Nuria Contreras, Carmen Escudero-Iriarte, Isabel Varela-Nieto, Pascal Maire, Ignacio Palmero

Development. 2023 May 1; 150(9): dev200903. Published online 2023 May 3. doi: 10.1242/dev.200903

PMCID:: PMC10259514

Abstract Article

Select item 1011042311.

Sp3 is essential for normal lung morphogenesis and cell cycle progression during mouse embryonic development

Alyssa M. McCoy, Omar Lakhdari, Sayane Shome, Kaitlin Caoili, Gilberto E. Hernandez, Nima Aghaeepour, Lindsay D. Butcher, Kathleen Fisch, Lawrence S. Prince

Development. 2023 Mar 1; 150(5): dev200839. Published online 2023 Mar 3. doi: 10.1242/dev.200839

PMCID:: PMC10110423

Abstract Article

Select item 987232112.

Neonatal inflammation increases hippocampal KCC2 expression through methylation-mediated TGF-β1 downregulation leading to impaired hippocampal cognitive function and synaptic plasticity in adult mice

Jing Rong, Yang Yang, Min Liang, Haiquan Zhong, Yingchun Li, Yichao Zhu, Sha Sha, Lei Chen, Rong Zhou

J Neuroinflammation. 2023; 20: 15. Published online 2023 Jan 23. doi: 10.1186/s12974-023-02697-x

PMCID:: PMC9872321

Abstract Article PDF–5.6M

Select item 977234613.

SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse

Aya Uchida, Kenya Imaimatsu, Honoka Suzuki, Xiao Han, Hiroki Ushioda, Mami Uemura, Kasane Imura-Kishi, Ryuji Hiramatsu, Hinako M. Takase, Yoshikazu Hirate, Atsuo Ogura, Masami Kanai-Azuma, Akihiko Kudo, Yoshiakira Kanai

Nat Commun. 2022; 13: 7860. Published online 2022 Dec 21. doi: 10.1038/s41467-022-35465-1

PMCID:: PMC9772346

Abstract Article PDF–15M

Select item 973996714.

TGF-β2 Regulates Transcription of the K⁺/Cl⁻ Cotransporter 2 (KCC2) in Immature Neurons and Its Phosphorylation at T1007 in Differentiated Neurons

Anastasia Rigkou, Attila Magyar, Jan Manuel Speer, Eleni Roussa

Cells. 2022 Dec; 11(23): 3861. Published online 2022 Nov 30. doi: 10.3390/cells11233861

PMCID:: PMC9739967

Abstract Article PDF–3.4M

Select item 971371615.

Maternal immune activation leads to defective brain–blood vessels and intracerebral hemorrhages in male offspring

Marco Rasile, Eliana Lauranzano, Elisa Faggiani, Margherita M Ravanelli, Federico S Colombo, Filippo Mirabella, Irene Corradini, Maria L Malosio, Antonella Borreca, Elisa Focchi, Davide Pozzi, Toni Giorgino, Isabella Barajon, Michela Matteoli

EMBO J. 2022 Dec; 41(23): e111192. Published online 2022 Oct 31. doi: 10.15252/embj.2022111192

Correction in:: EMBO J. 2023 May; 42(10): e113890.

PMCID:: PMC9713716

Abstract Article PDF–3.2M

Select item 962426216.

Endothelial loss of ETS1 impairs coronary vascular development and leads to ventricular non-compaction

Lu Wang, Lizhu Lin, Hui Qi, Ju Chen, Paul Grossfeld

Circ Res. Author manuscript; available in PMC 2023 Aug 19.

Published in final edited form as: Circ Res. 2022 Aug 19; 131(5): 371–387. Published online 2022 Jul 27. doi: 10.1161/CIRCRESAHA.121.319955

PMCID:: PMC9624262

Abstract Article PDF–4.5M

Select item 898800817.

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

Ann-Helen Rosendahl, Mia Monnius, Anu Laitala, Antti Railo, Ilkka Miinalainen, Ritva Heljasvaara, Joni M. Mäki, Johanna Myllyharju

J Biol Chem. 2022 Apr; 298(4): 101787. Published online 2022 Mar 2. doi: 10.1016/j.jbc.2022.101787

PMCID:: PMC8988008

Abstract Article PDF–6.1M

Select item 891454818.

TFPI2 suppresses the interaction of TGF-β2 pathway regulators to promote endothelial–mesenchymal transition in diabetic nephropathy

Guoying Guan, Jinjiao Xie, Yamei Dai, Hui Han

J Biol Chem. 2022 Mar; 298(3): 101725. Published online 2022 Feb 11. doi: 10.1016/j.jbc.2022.101725

PMCID:: PMC8914548

Abstract Article PDF–7.7M

Select item 876711119.

TGFβ2 Induces the Soluble Isoform of CTLA-4 – Implications for CTLA-4 Based Checkpoint Inhibitor Antibodies in Malignant Melanoma

Rahul C. Khanolkar, Chu Zhang, Farah Al-Fatyan, Linda Lawson, Ivan Depasquale, Fiona M. Meredith, Frank Muller, Marianne Nicolson, Lekh Nath Dahal, Rasha Abu-Eid, Sanjay Rajpara, Robert Norman Barker, Anthony D. Ormerod, Frank James Ward

Front Immunol. 2021; 12: 763877. Published online 2022 Jan 5. doi: 10.3389/fimmu.2021.763877