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Items: 1 to 20 of 33

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Genetic and pharmacologic inhibition of ALDH1A3 as a treatment of β-cell failure
Jinsook Son, Wen Du, Mark Esposito, Kaavian Shariati, Hongxu Ding, Yibin Kang, Domenico Accili
Nat Commun. 2023; 14: 558. Published online 2023 Feb 2. doi: 10.1038/s41467-023-36315-4
PMCID:
PMC9895451
AbstractArticlePDF–2.5M
3.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
4.
Generation and characterization of Aldh3-Cre transgenic mice as a tool for conditional gene deletion in postnatal cornea
Sweetu Susan Sunny, Jitka Lachova, Naoko Dupacova, Anna Zitova, Zbynek Kozmik
Sci Rep. 2020; 10: 9083. Published online 2020 Jun 3. doi: 10.1038/s41598-020-65878-1
PMCID:
PMC7270111
AbstractArticlePDF–3.6M
5.
Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma
Abigail G Zieman, Brian G Poll, Jingqun Ma, Pierre A Coulombe
Hum Mol Genet. 2019 Jul 1; 28(13): 2255–2270. Published online 2019 Mar 20. doi: 10.1093/hmg/ddz050
PMCID:
PMC6602407
AbstractArticlePDF–3.5M
6.
Mutation of the gene encoding the circadian clock component PERIOD2 in oncogenic cells confers chemoresistance by up-regulating the Aldh3a1 gene
Chiharu Katamune, Satoru Koyanagi, Ken-ichi Hashikawa, Naoki Kusunose, Takahiro Akamine, Naoya Matsunaga, Shigehiro Ohdo
J Biol Chem. 2019 Jan 11; 294(2): 547–558. Published online 2018 Nov 14. doi: 10.1074/jbc.RA118.004942
PMCID:
PMC6333901
AbstractArticlePDF–3.0M
7.
Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes
Julie P. Saiki, Hongbin Cao, Lauren D. Van Wassenhove, Vignesh Viswanathan, Joshua Bloomstein, Dhanya K. Nambiar, Aaron J. Mattingly, Dadi Jiang, Che-Hong Chen, Matthew C. Stevens, Amanda L. Simmons, Hyun Shin Park, Rie von Eyben, Eric T. Kool, Davud Sirjani, Sarah M. Knox, Quynh Thu Le, Daria Mochly-Rosen
Proc Natl Acad Sci U S A. 2018 Jun 12; 115(24): 6279–6284. Published online 2018 May 24. doi: 10.1073/pnas.1802184115
PMCID:
PMC6004437
AbstractArticlePDF–1.2M
8.
Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development
Vinay Bulusu, Nicole Prior, Marteinn T. Snaebjornsson, Andreas Kuehne, Katharina F. Sonnen, Jana Kress, Frank Stein, Carsten Schultz, Uwe Sauer, Alexander Aulehla
Dev Cell. 2017 Feb 27; 40(4): 331–341.e4. doi: 10.1016/j.devcel.2017.01.015
PMCID:
PMC5337618
AbstractArticle
9.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
10.
Severe muscle wasting and denervation in mice lacking the RNA-binding protein ZFP106
Douglas M. Anderson, Jessica Cannavino, Hui Li, Kelly M. Anderson, Benjamin R. Nelson, John McAnally, Svetlana Bezprozvannaya, Yun Liu, Weichun Lin, Ning Liu, Rhonda Bassel-Duby, Eric N. Olson
Proc Natl Acad Sci U S A. 2016 Aug 2; 113(31): E4494–E4503. Published online 2016 Jul 14. doi: 10.1073/pnas.1608423113
PMCID:
PMC4978283
AbstractArticlePDF–2.3M
11.
ALDH3A1 Plays a Functional Role in Maintenance of Corneal Epithelial Homeostasis
Vindhya Koppaka, Ying Chen, Gaurav Mehta, David J. Orlicky, David C. Thompson, James V. Jester, Vasilis Vasiliou
PLoS One. 2016; 11(1): e0146433. Published online 2016 Jan 11. doi: 10.1371/journal.pone.0146433
PMCID:
PMC4708999
AbstractArticlePDF–7.2M
12.
Pharmacological recruitment of aldehyde dehydrogenase 3A1 (ALDH3A1) to assist ALDH2 in acetaldehyde and ethanol metabolism in vivo
Che-Hong Chen, Leslie A. Cruz, Daria Mochly-Rosen
Proc Natl Acad Sci U S A. 2015 Mar 10; 112(10): 3074–3079. Published online 2015 Feb 23. doi: 10.1073/pnas.1414657112
PMCID:
PMC4364197
AbstractArticlePDF–994K
13.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
14.
A role for chromosomal protein HMGN1 in corneal maturation
Yehudit Birger, Janine Davis, Takashi Furusawa, Eyal Rand, Joram Piatigorsky, Michael Bustin
Differentiation. Author manuscript; available in PMC 2013 Aug 1.
Published in final edited form as: Differentiation. 2006 Feb; 74(1): 19–29. doi: 10.1111/j.1432-0436.2006.00054.x
PMCID:
PMC3730489
AbstractArticlePDF–3.4M
15.
Functional Expression of the New Gap Junction Gene Connexin47 Transcribed in Mouse Brain and Spinal Cord Neurons
Barbara Teubner, Benjamin Odermatt, Martin Güldenagel, Goran Söhl, Joachim Degen, Feliksas F. Bukauskas, Jack Kronengold, Vytas K. Verselis, Yong Tae Jung, Christine A. Kozak, Karl Schilling, Klaus Willecke
J Neurosci. 2001 Feb 15; 21(4): 1117–1126. doi: 10.1523/JNEUROSCI.21-04-01117.2001
PMCID:
PMC3671913
AbstractArticlePDF–574K
16.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
17.
Endogenous acetaldehyde toxicity during antral follicular development in the mouse ovary
Tomoko Kawai, Toshihiro Mihara, Ikko Kawashima, Youko Fujita, Chiaki Ikeda, Hiroaki Negishi, JoAnne S. Richards, Masayuki Shimada
Reprod Toxicol. Author manuscript; available in PMC 2013 Jun 1.
Published in final edited form as: Reprod Toxicol. 2012 Jun; 33(3): 322–330. Published online 2012 Jan 18. doi: 10.1016/j.reprotox.2012.01.001
PMCID:
PMC3327754
AbstractArticlePDF–1.4M
18.
Short-Chain 3-Hydroxyacyl-Coenzyme A Dehydrogenase Associates with a Protein Super-Complex Integrating Multiple Metabolic Pathways
Srinivas B. Narayan, Stephen R. Master, Anthony N. Sireci, Charlene Bierl, Paige E. Stanley, Changhong Li, Charles A. Stanley, Michael J. Bennett
PLoS One. 2012; 7(4): e35048. Published online 2012 Apr 9. doi: 10.1371/journal.pone.0035048
PMCID:
PMC3322157
AbstractArticlePDF–219K
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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