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Items: 1 to 20 of 55

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Glutathione limits RUNX2 oxidation and degradation to regulate bone formation
Guoli Hu, Yilin Yu, Deepika Sharma, Shondra M. Pruett-Miller, Yinshi Ren, Guo-Fang Zhang, Courtney M. Karner
JCI Insight. 2023 Aug 22; 8(16): e166888. Published online 2023 Aug 22. doi: 10.1172/jci.insight.166888
PMCID:
PMC10543723
AbstractArticlePDF–11M
3.
Differential effects of glutamine inhibition strategies on anti-tumor CD8 T cells
Matthew Z. Madden, Xiang Ye, Channing Chi, Emilie L. Fisher, Melissa M. Wolf, Gabriel A. Needle, Jackie E. Bader, Andrew R. Patterson, Bradley I. Reinfeld, Madelyn D. Landis, Emma S. Hathaway, Jason E. Muka, Richard T. O’Neil, John Karijolich, Mary Philip, Jeffrey C. Rathmell
J Immunol. Author manuscript; available in PMC 2024 Aug 15.
Published in final edited form as: J Immunol. 2023 Aug 15; 211(4): 563–575. doi: 10.4049/jimmunol.2200715
PMCID:
PMC10526752
AbstractArticlePDF–2.9M
4.
Epigenetic regulation of IPF fibroblast phenotype by glutaminolysis
Zheyi Xiang, Le Bai, Jennifer Q. Zhou, Ricardo R. Cevallos, Jonathan R. Sanders, Gang Liu, Karen Bernard, Yan Y. Sanders
Mol Metab. 2023 Jan; 67: 101655. Published online 2022 Dec 13. doi: 10.1016/j.molmet.2022.101655
PMCID:
PMC9827063
AbstractArticlePDF–2.0M
5.
NKT cells adopt a glutamine-addicted phenotype to regulate their homeostasis and function
Ajay Kumar, Emily L. Yarosz, Anthony Andren, Li Zhang, Costas A. Lyssiotis, Cheong-Hee Chang
Cell Rep. Author manuscript; available in PMC 2022 Nov 15.
Published in final edited form as: Cell Rep. 2022 Oct 25; 41(4): 111516. doi: 10.1016/j.celrep.2022.111516
PMCID:
PMC9664378
AbstractArticlePDF–2.5M
6.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
7.
Pharmacological Inhibition of Glutaminase 1 Normalized the Metabolic State and CD4+ T Cell Response in Sjogren's Syndrome
Jiayao Fu, Yiping Pu, Baoli Wang, Hui Li, Xiujuan Yang, Lisong Xie, Huan Shi, Zhijun Wang, Junhao Yin, Tianle Zhan, Yanxiong Shao, Changyu Chen, Qi Luo, Jiabao Xu, Zirui Zong, Xindi Wei, Wanwen Xiao, Chuangqi Yu, Lingyan Zheng
J Immunol Res. 2022; 2022: 3210200. Published online 2022 Feb 15. doi: 10.1155/2022/3210200
PMCID:
PMC8863479
AbstractArticlePDF–3.0M
8.
Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation
Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley
Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h
PMCID:
PMC8763317
AbstractArticle
9.
The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins
Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo
BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y
PMCID:
PMC8744257
AbstractArticlePDF–6.0M
10.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
11.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
12.
Nrf2 Activation Sensitizes K-Ras Mutant Pancreatic Cancer Cells to Glutaminase Inhibition
Shin Hamada, Ryotaro Matsumoto, Yu Tanaka, Keiko Taguchi, Masayuki Yamamoto, Atsushi Masamune
Int J Mol Sci. 2021 Feb; 22(4): 1870. Published online 2021 Feb 14. doi: 10.3390/ijms22041870
PMCID:
PMC7918355
AbstractArticlePDF–1.1M
13.
Etomoxir regulates the differentiation of male germ cells by specifically reducing H3K27ac level
Yushan Xu, Jue Xie
BMC Dev Biol. 2021; 21: 5. Published online 2021 Feb 1. doi: 10.1186/s12861-020-00237-x
PMCID:
PMC7849134
AbstractArticlePDF–4.8M
14.
Identifying strategies to target the metabolic flexibility of tumours.
Andrés Méndez-Lucas, Wei Lin, Paul C. Driscoll, Nathalie Legrave, Laura Novellasdemunt, Chencheng Xie, Mark Charles, Zena Wilson, Neil P. Jones, Stephen Rayport, Manuel Rodríguez-Justo, Vivian Li, James I. MacRae, Nissim Hay, Xin Chen, Mariia Yuneva
Nat Metab. Author manuscript; available in PMC 2020 Oct 21.
Published in final edited form as: Nat Metab. 2020 Apr; 2(4): 335–350. Published online 2020 Apr 21. doi: 10.1038/s42255-020-0195-8
PMCID:
PMC7436715
AbstractArticlePDF–7.2M
15.
Targeting hepatic Glutaminase 1 ameliorates Non-Alcoholic Steatohepatitis by restoring Very-Low Density Lipoproteins triglyceride assembly
Jorge Simon, Maitane Nuñez-García, Pablo Fernández-Tussy, Lucía Barbier-Torres, David Fernández-Ramos, Beatriz Gómez-Santos, Xabier Buqué, Fernando Lopitz-Otsoa, Naroa Goikoetxea-Usandizaga, Marina Serrano-Macia, Rubén Rodriguez-Agudo, Maider Bizkarguenaga, Imanol Zubiete-Franco, Virginia Gutiérrez-de Juan, Diana Cabrera, Cristina Alonso, Paula Iruzubieta, Manuel Romero-Gomez, Sebastiaan van Liempd, Azucena Castro, Ruben Nogueiras, Marta Varela-Rey, Juan Manuel Falcón-Pérez, Erica Villa, Javier Crespo, Shelly C. Lu, Jose M. Mato, Patricia Aspichueta, Teresa Cardoso Delgado, María Luz Martínez-Chantar
Cell Metab. Author manuscript; available in PMC 2021 Mar 3.
Published in final edited form as: Cell Metab. 2020 Mar 3; 31(3): 605–622.e10. Published online 2020 Feb 21. doi: 10.1016/j.cmet.2020.01.013
PMCID:
PMC7259377
AbstractArticlePDF–1.4M
16.
Macrophage-derived glutamine boosts satellite cells and muscle regeneration
Min Shang, Federica Cappellesso, Ricardo Amorim, Jens Serneels, Federico Virga, Guy Eelen, Stefania Carobbio, Melvin Y. Rincon, Pierre Maechler, Katrien De Bock, Ping-Chih Ho, Marco Sandri, Bart Ghesquiere, Peter Carmeliet, Mario Di Matteo, Emanuele Berardi, Massimiliano Mazzone
Nature. Author manuscript; available in PMC 2021 Apr 28.
Published in final edited form as: Nature. 2020 Nov 1; 587(7835): 626–631. Published online 2020 Oct 28. doi: 10.1038/s41586-020-2857-9
PMCID:
PMC7116844
AbstractArticlePDF–5.9M
17.
Glutamine metabolism regulates proliferation and lineage allocation in skeletal stem cells
Yilin Yu, Hunter Newman, Leyao Shen, Deepika Sharma, Guoli Hu, Anthony J. Mirando, Hongyuan Zhang, Everett Knudsen, Guo-Fang Zhang, Matthew J. Hilton, Courtney M. Karner
Cell Metab. Author manuscript; available in PMC 2020 Apr 2.
Published in final edited form as: Cell Metab. 2019 Apr 2; 29(4): 966–978.e4. Published online 2019 Feb 14. doi: 10.1016/j.cmet.2019.01.016
PMCID:
PMC7062112
AbstractArticlePDF–2.5M
18.
The activation loop and substrate-binding cleft of glutaminase C are allosterically coupled
Yunxing Li, Sekar Ramachandran, Thuy-Tien T. Nguyen, Clint A. Stalnecker, Richard A. Cerione, Jon W. Erickson
J Biol Chem. 2020 Jan 31; 295(5): 1328–1337. Published online 2019 Dec 23. doi: 10.1074/jbc.RA119.010314
PMCID:
PMC6996896
AbstractArticlePDF–2.2M
19.
Glutaminase 1 Inhibition Reduces Glycolysis and Ameliorates Lupus-like Disease in MRL/lpr Mice and Experimental Autoimmune Encephalomyelitis
Michihito Kono, Nobuya Yoshida, Kayaho Maeda, Abel Suárez-Fueyo, Vasileios C. Kyttaris, George C. Tsokos
Arthritis Rheumatol. Author manuscript; available in PMC 2020 Nov 1.
Published in final edited form as: Arthritis Rheumatol. 2019 Nov; 71(11): 1869–1878. Published online 2019 Sep 27. doi: 10.1002/art.41019
PMCID:
PMC6817384
AbstractArticle
20.
Specification of Spatial Identities of Cerebellar Neuron Progenitors by Ptf1a and Atoh1 for Proper Production of GABAergic and Glutamatergic Neurons
Mayumi Yamada, Yusuke Seto, Shinichiro Taya, Tomoo Owa, Yukiko U. Inoue, Takayoshi Inoue, Yoshiya Kawaguchi, Yo-ichi Nabeshima, Mikio Hoshino
J Neurosci. 2014 Apr 2; 34(14): 4786–4800. doi: 10.1523/JNEUROSCI.2722-13.2014
PMCID:
PMC6802724
AbstractArticlePDF–13M

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