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Items: 1 to 20 of 31

1.
FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia
Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen
J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0
PMCID:
PMC9922468
AbstractArticlePDF–4.9M
2.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
3.
The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari
PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412
PMCID:
PMC8513853
AbstractArticlePDF–4.1M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
6.
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis
Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu
iScience. 2019 Sep 27; 19: 1114–1132. Published online 2019 Sep 4. doi: 10.1016/j.isci.2019.08.057
PMCID:
PMC6831851
AbstractArticlePDF–9.8M
7.
The T99K variant of glycosylasparaginase shows a new structural mechanism of the genetic disease aspartylglucosaminuria
Suchita Pande, Hwai‐Chen Guo
Protein Sci. 2019 Jun; 28(6): 1013–1023. Published online 2019 Apr 9. doi: 10.1002/pro.3607
PMCID:
PMC6511735
AbstractArticlePDF–1.0M
8.
Biochemical and Structural Insights into an Allelic Variant Causing the Lysosomal Storage Disorder Aspartylglucosaminuria
Suchita Pande, William Bizilj, Hwai-Chen Guo
FEBS Lett. Author manuscript; available in PMC 2019 Aug 1.
Published in final edited form as: FEBS Lett. 2018 Aug; 592(15): 2550–2561. Published online 2018 Jul 23. doi: 10.1002/1873-3468.13190
PMCID:
PMC6119092
AbstractArticlePDF–876K
9.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
10.
Crystal structure of a mutant glycosylasparaginase shedding light on aspartylglycosaminurea-causing mechanism as well as on hydrolysis of non-chitobiose substrate
Suchita Pande, Damodharan Lakshminarasimhan, Hwai-Chen Guo
Mol Genet Metab. Author manuscript; available in PMC 2018 Jun 1.
Published in final edited form as: Mol Genet Metab. 2017 Jun; 121(2): 150–156. Published online 2017 Apr 19. doi: 10.1016/j.ymgme.2017.04.008
PMCID:
PMC5504686
AbstractArticlePDF–639K
11.
Development of a model system for neuronal dysfunction in Fabry Disease
Christine R. Kaneski, Roscoe O. Brady, John A. Hanover, Ulrike H. Schueler
Mol Genet Metab. Author manuscript; available in PMC 2017 Sep 1.
Published in final edited form as: Mol Genet Metab. 2016 Sep; 119(1-2): 144–150. Published online 2016 Jul 22. doi: 10.1016/j.ymgme.2016.07.010
PMCID:
PMC5031533
AbstractArticlePDF–893K
12.
BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein
Sadiya Malik, Hiroko Saito, Miho Takaoka, Yoshio Miki, Akira Nakanishi
Cell Cycle. 2016; 15(16): 2145–2156. Published online 2016 Jul 19. doi: 10.1080/15384101.2016.1195531
PMCID:
PMC4993541
AbstractArticlePDF–1.6M
13.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
14.
Human Neutrophils Secrete Bioactive Paucimannosidic Proteins from Azurophilic Granules into Pathogen-Infected Sputum
Morten Thaysen-Andersen, Vignesh Venkatakrishnan, Ian Loke, Christine Laurini, Simone Diestel, Benjamin L. Parker, Nicolle H. Packer
J Biol Chem. 2015 Apr 3; 290(14): 8789–8802. Published online 2015 Feb 2. doi: 10.1074/jbc.M114.631622
PMCID:
PMC4423670
AbstractArticlePDF–3.0M
15.
No evidence of gene-calcium interactions from genome-wide analysis of colorectal cancer risk
Mengmeng Du, Xuehong Zhang, Michael Hoffmeister, Robert E. Schoen, John A. Baron, Sonja I. Berndt, Hermann Brenner, Christopher S. Carlson, Graham Casey, Andrew T. Chan, Keith R. Curtis, David Duggan, W. James Gauderman, Edward L. Giovannucci, Jian Gong, Tabitha A. Harrison, Richard B. Hayes, Brian E. Henderson, John L. Hopper, Li Hsu, Thomas J. Hudson, Carolyn M. Hutter, Mark A. Jenkins, Shuo Jiao, Jonathan M. Kocarnik, Laurence N. Kolonel, Loic Le Marchand, Yi Lin, Polly A. Newcomb, Anja Rudolph, Daniela Seminara, Mark D. Thornquist, Cornelia M. Ulrich, Emily White, Kana Wu, Brent W. Zanke, Peter T. Campbell, Martha L. Slattery, Ulrike Peters, Jenny Chang-Claude, John D. Potter, on behalf of the Colon Cancer Family Registry and Genetics and Epidemiology of Colorectal Cancer Consortium
Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2015 Dec 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2014 Dec; 23(12): 2971–2976. Published online 2014 Sep 5. doi: 10.1158/1055-9965.EPI-14-0893
PMCID:
PMC4257872
AbstractArticlePDF–1.2M
16.
Genome-wide association study for biomarker identification of Rapamycin and Everolimus using a lymphoblastoid cell line system
Jing Jiang, Brooke L. Fridley, Qiping Feng, Ryan P. Abo, Abra Brisbin, Anthony Batzler, Gregory Jenkins, Pamela A. Long, Liewei Wang
Front Genet. 2013; 4: 166. Published online 2013 Aug 30. doi: 10.3389/fgene.2013.00166
PMCID:
PMC3757297
AbstractArticlePDF–2.6M
17.
Genome-Wide Association Study of Serum Selenium Concentrations
Jian Gong, Li Hsu, Tabitha Harrison, Irena B. King, Stefan Stürup, Xiaoling Song, David Duggan, Yan Liu, Carolyn Hutter, Stephen J. Chanock, Charles B. Eaton, James R. Marshall, Ulrike Peters
Nutrients. 2013 May; 5(5): 1706–1718. Published online 2013 May 21. doi: 10.3390/nu5051706
PMCID:
PMC3708345
AbstractArticlePDF–476K
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano
Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406
PMCID:
PMC1356129
AbstractArticlePDF–438K
20.
Autoproteolytic activation of human aspartylglucosaminidase.
Jani Saarela, Carita Oinonen, Anu Jalanko, Juha Rouvinen, Leena Peltonen
Biochem J. 2004 Mar 1; 378(Pt 2): 363–371. doi: 10.1042/BJ20031496
PMCID:
PMC1223969
SummaryPDF–315K

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