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Items: 1 to 20 of 122

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Evidence for Crosstalk between the Aryl Hydrocarbon Receptor and the Translocator Protein in Mouse Lung Epithelial Cells
Michelle M. Steidemann, Jian Liu, Kalin Bayes, Lizbeth P. Castro, Shelagh Ferguson-Miller, John J. LaPres
Exp Cell Res. Author manuscript; available in PMC 2024 Aug 1.
Published in final edited form as: Exp Cell Res. 2023 Aug 1; 429(1): 113617. Published online 2023 May 10. doi: 10.1016/j.yexcr.2023.113617
PMCID:
PMC10330775
AbstractArticlePDF–1.4M
3.
Monoterpenoid aryl hydrocarbon receptor allosteric antagonists protect against ultraviolet skin damage in female mice
Karolína Ondrová, Iveta Zůvalová, Barbora Vyhlídalová, Kristýna Krasulová, Eva Miková, Radim Vrzal, Petr Nádvorník, Binod Nepal, Sandhya Kortagere, Martina Kopečná, David Kopečný, Marek Šebela, Fraydoon Rastinejad, Hua Pu, Miroslav Soural, Katharina Maria Rolfes, Thomas Haarmann-Stemmann, Hao Li, Sridhar Mani, Zdeněk Dvořák
Nat Commun. 2023; 14: 2728. Published online 2023 May 11. doi: 10.1038/s41467-023-38478-6
PMCID:
PMC10174618
AbstractArticlePDF–3.4M
4.
Aryl hydrocarbon receptor nuclear translocator limits the recruitment and function of regulatory neutrophils against colorectal cancer by regulating the gut microbiota
Yujing Bi, Qiuli Yang, Zhengchao Li, Yuexin Wang, Yufei Wang, Anna Jia, Zhiyuan Pan, Ruifu Yang, Guangwei Liu
J Exp Clin Cancer Res. 2023; 42: 53. Published online 2023 Mar 1. doi: 10.1186/s13046-023-02627-y
PMCID:
PMC9976387
AbstractArticlePDF–2.3M
5.
Compartmentalized metabolism supports midgestation mammalian development
Ashley Solmonson, Brandon Faubert, Wen Gu, Aparna Rao, Mitzy A. Cowdin, Ivan Menendez-Montes, Sherwin Kelekar, Thomas J. Rogers, Chunxiao Pan, Gerardo Guevara, Amy Tarangelo, Lauren G. Zacharias, Misty S. Martin-Sandoval, Duyen Do, Panayotis Pachnis, Dennis Dumesnil, Thomas P. Mathews, Alpaslan Tasdogan, An Pham, Ling Cai, Zhiyu Zhao, Min Ni, Ondine Cleaver, Hesham A. Sadek, Sean J. Morrison, Ralph J. DeBerardinis
Nature. 2022; 604(7905): 349–353. Published online 2022 Apr 6. doi: 10.1038/s41586-022-04557-9
PMCID:
PMC9007737
AbstractArticlePDF–6.0M
6.
Endothelial Aryl Hydrocarbon Receptor Nuclear Translocator Mediates the Angiogenic Response to Peripheral Ischemia in Mice With Type 2 Diabetes Mellitus
Tu Nguyen, Mei Zheng, Maura Knapp, Nikola Sladojevic, Qin Zhang, Lizhuo Ai, Devin Harrison, Anna Chen, Albert Sitikov, Le Shen, Frank J. Gonzalez, Qiong Zhao, Yun Fang, James J. K. Liao, Rongxue Wu
Front Cell Dev Biol. 2021; 9: 691801. Published online 2021 Jun 10. doi: 10.3389/fcell.2021.691801
PMCID:
PMC8222825
AbstractArticlePDF–3.5M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Effects of Myeloid Hif-1β Deletion on the Intestinal Microbiota in Mice under Environmental Hypoxia
Ni Han, Zhiyuan Pan, Zongyu Huang, Yuxiao Chang, Fengyi Hou, Guangwei Liu, Ruifu Yang, Yujing Bi
Infect Immun. 2021 Jan; 89(1): e00474-20. Prepublished online 2020 Oct 26. Published online 2020 Dec 15. doi: 10.1128/IAI.00474-20
PMCID:
PMC7927920
AbstractArticlePDF–2.4M
9.
Loss of ARNT in skeletal muscle limits muscle regeneration in aging
Yori Endo, Kodi Baldino, Bin Li, Yuteng Zhang, Dharaniya Sakthivel, Michael MacArthur, Adriana C. Panayi, Peter Kip, Daniel J. Spencer, Ravi Jasuja, Debalina Bagchi, Shalender Bhasin, Kristo Nuutila, Ronald L. Neppl, Amy J. Wagers, Indranil Sinha
FASEB J. 2020 Dec; 34(12): 16086–16104. Published online 2020 Oct 8. doi: 10.1096/fj.202000761RR
PMCID:
PMC7756517
AbstractArticlePDF–2.1M
10.
Dissociation of the AhR/ARNT complex by TGF-β/Smad signaling represses CYP1A1 gene expression and inhibits benze[a]pyrene-mediated cytotoxicity
Naoko Nakano, Nobuo Sakata, Yuki Katsu, Daiki Nochise, Erika Sato, Yuta Takahashi, Saori Yamaguchi, Yoko Haga, Souichi Ikeno, Mitsuyoshi Motizuki, Keigo Sano, Kohei Yamasaki, Keiji Miyazawa, Susumu Itoh
J Biol Chem. 2020 Jul 3; 295(27): 9033–9051. Published online 2020 May 14. doi: 10.1074/jbc.RA120.013596
PMCID:
PMC7335805
AbstractArticlePDF–4.4M
11.
Targeting glutamine metabolism slows soft tissue sarcoma growth
Pearl Lee, Dania Malik, Nicholas Perkons, Peiwei Huangyang, Sanika Khare, Seth Rhoades, Yao-Yu Gong, Michelle Burrows, Jennifer M. Finan, Itzhak Nissim, Terence P. F. Gade, Aalim M. Weljie, M. Celeste Simon
Nat Commun. 2020; 11: 498. Published online 2020 Jan 24. doi: 10.1038/s41467-020-14374-1
Correction in:
Nat Commun. 2024; 15: 7524.
PMCID:
PMC6981153
AbstractArticlePDF–4.5M
12.
Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis
Christopher Scott, Rebecca Stokes, Kuan Minn Cha, Andrew Clouston, Mohammed Eslam, Mayda Metwally, Michael M. Swarbrick, Jacob George, Jenny E. Gunton
PLoS One. 2019; 14(12): e0225332. Published online 2019 Dec 4. doi: 10.1371/journal.pone.0225332
PMCID:
PMC6892561
AbstractArticlePDF–3.4M
13.
The Loss of ARNT/HIF1β in Male Pancreatic β-Cells Is Protective Against High-Fat Diet–Induced Diabetes
Monica Hoang, Sabina Paglialunga, Eric Bombardier, A Russell Tupling, Jamie W Joseph
Endocrinology. 2019 Dec; 160(12): 2825–2836. Published online 2019 Oct 3. doi: 10.1210/en.2018-00936
PMCID:
PMC6846328
AbstractArticle
14.
Leishmania Infection Induces Macrophage Vascular Endothelial Growth Factor A Production in an ARNT/HIF-Dependent Manner
Tiffany Weinkopff, Hayden Roys, Anne Bowlin, Phillip Scott
Infect Immun. 2019 Nov; 87(11): e00088-19. Prepublished online 2019 Aug 26. Published online 2019 Oct 18. doi: 10.1128/IAI.00088-19
Correction in:
Infect Immun. 2022 Apr; 90(4): e00019-22.
PMCID:
PMC6803331
AbstractArticlePDF–1.0M
15.
Synergistic effects of genetic beta cell dysfunction and maternal glucose intolerance on offspring metabolic phenotype in mice
S. M. Lau, S. Lin, R. A. Stokes, K. Cheng, P. A. Baldock, R. F. Enriquez, M. McLean, N. W. Cheung, A. Sainsbury, F. J. Gonzalez, H. Herzog, J. E. Gunton
Diabetologia. Author manuscript; available in PMC 2019 Jun 26.
Published in final edited form as: Diabetologia. 2011 Apr; 54(4): 910–921. Published online 2010 Dec 22. doi: 10.1007/s00125-010-1998-z
PMCID:
PMC6594150
AbstractArticlePDF–886K
16.
Deletion of ARNT/HIF1β in pancreatic beta cells does not impair glucose homeostasis in mice, but is associated with defective glucose sensing ex vivo
Renjitha Pillai, Sabina Paglialunga, Monica Hoang, Katelyn Cousteils, Kacey J. Prentice, Eric Bombardier, Mei Huang, Frank J. Gonzalez, A. Russell Tupling, Michael B. Wheeler, Jamie W. Joseph
Diabetologia. Author manuscript; available in PMC 2019 Jan 18.
Published in final edited form as: Diabetologia. 2015 Dec; 58(12): 2832–2842. Published online 2015 Sep 26. doi: 10.1007/s00125-015-3768-4
PMCID:
PMC6338330
AbstractArticlePDF–895K
17.
Molecular Characterization of the Murine Hif-1α Locus
Gang Luo, Yi-Zhong Gu, Sanjay Jain, William K. Chan, Kristen M. Carr, John B. Hogenesch, Christopher A. Bradfield
Gene Expr. 1997; 6(5): 287–299. Published online 2018 Sep 21.
PMCID:
PMC6148284
AbstractArticlePDF–3.0M
18.
Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure
Björn Tampe, Désirée Tampe, Gunsmaa Nyamsuren, Friederike Klöpper, Gregor Rapp, Anne Kauffels, Thomas Lorf, Elisabeth M. Zeisberg, Gerhard A. Müller, Raghu Kalluri, Samy Hakroush, Michael Zeisberg
J Clin Invest. 2018 Jul 2; 128(7): 3053–3070. Published online 2018 Jun 11. doi: 10.1172/JCI89632
PMCID:
PMC6025987
AbstractArticlePDF–36M
19.
Aryl Hydrocarbon Receptor Nuclear Translocator in Vascular Smooth Muscle Cells Is Required for Optimal Peripheral Perfusion Recovery
Anna Henry Borton, Bryan L. Benson, Lee E. Neilson, Ashley Saunders, M. Amer Alaiti, Alex Y. Huang, Mukesh K. Jain, Aaron Proweller, Diana L. Ramirez‐Bergeron
J Am Heart Assoc. 2018 Jun 5; 7(11): e009205. Published online 2018 Jun 1. doi: 10.1161/JAHA.118.009205
PMCID:
PMC6015385
AbstractArticlePDF–3.2M
20.
Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development
Xiaomin Su, Chenglei Wu, Xiaoying Ye, Ming Zeng, Zhujun Zhang, Yongzhe Che, Yuan Zhang, Lin Liu, Yushuang Lin, Rongcun Yang
Cell Death Dis. 2018 Mar; 9(3): 302. Published online 2018 Feb 21. doi: 10.1038/s41419-018-0370-y
PMCID:
PMC5833458
AbstractArticlePDF–2.3M

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