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Select item 105456331.

Choroid plexus mis-splicing and altered cerebrospinal fluid composition in myotonic dystrophy type 1

Curtis A Nutter, Benjamin M Kidd, Helmut A Carter, Johanna I Hamel, Philip M Mackie, Nayha Kumbkarni, Mackenzie L Davenport, Dana M Tuyn, Adithya Gopinath, Peter D Creigh, Łukasz J Sznajder, Eric T Wang, Laura P W Ranum, Habibeh Khoshbouei, John W Day, Jacinda B Sampson, Stefan Prokop, Maurice S Swanson

Brain. 2023 Oct; 146(10): 4217–4232. Published online 2023 May 5. doi: 10.1093/brain/awad148

PMCID:: PMC10545633

Abstract Article PDF–1.5M

Select item 103003002.

Reprogramming astrocytic NDRG2/NF-κB/C3 signaling restores the diabetes-associated cognitive dysfunction

Tao Jiang, Yansong Li, Shuxuan He, Ning Huang, Mengyu Du, Qian Zhai, Kairui Pu, Meiyan Wu, Chaoying Yan, Zhi Ma, Qiang Wang

eBioMedicine. 2023 Jul; 93: 104653. Published online 2023 Jun 15. doi: 10.1016/j.ebiom.2023.104653

PMCID:: PMC10300300

Abstract Article PDF–4.3M

Select item 100749643.

ROS promote hyper-methylation of NDRG2 promoters in a DNMTS-dependent manner: Contributes to the progression of renal fibrosis

Yanfang Zhao, Xiaoting Fan, Qimeng Wang, Junhui Zhen, Xia Li, Ping Zhou, Yating Lang, Qinghao Sheng, Tingwei Zhang, Tongtong Huang, Yucheng Zhao, Zhimei Lv, Rong Wang

Redox Biol. 2023 Jun; 62: 102674. Published online 2023 Mar 21. doi: 10.1016/j.redox.2023.102674

PMCID:: PMC10074964

Abstract Article PDF–23M

Select item 97935554.

Lactate attenuates astrocytic inflammation by inhibiting ubiquitination and degradation of NDRG2 under oxygen–glucose deprivation conditions

Jinying Xu, Tong Ji, Guichen Li, Haiying Zhang, Yangyang Zheng, Meiying Li, Jie Ma, Yulin Li, Guangfan Chi

J Neuroinflammation. 2022; 19: 314. Published online 2022 Dec 26. doi: 10.1186/s12974-022-02678-6

PMCID:: PMC9793555

Abstract Article PDF–4.6M

Select item 97118615.

Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration

Flavia Roşianu, Simeon R Mihaylov, Noreen Eder, Antonie Martiniuc, Suzanne Claxton, Helen R Flynn, Shamsinar Jalal, Marie-Charlotte Domart, Lucy Collinson, Mark Skehel, Ambrosius P Snijders, Matthias Krause, Sharon A Tooze, Sila K Ultanir

Life Sci Alliance. 2023 Feb; 6(2): e202201712. Published online 2022 Nov 29. doi: 10.26508/lsa.202201712

PMCID:: PMC9711861

Abstract Article PDF–10M

Select item 96038606.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 88065487.

Transcription factor Krüppel-like factor 5-regulated N-myc downstream-regulated gene 2 reduces IL-1β-induced chondrocyte inflammatory injury and extracellular matrix degradation

Xiaoliang Mei, Hao Din, Jianning Zhao, Jian Tong, Wei Zhu

Bioengineered. 2021; 12(1): 7020–7032. Published online 2021 Sep 23. doi: 10.1080/21655979.2021.1971483

PMCID:: PMC8806548

Abstract Article PDF–3.8M

Select item 83132398.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79387709.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 758188510.

NDRG2 regulates adherens junction integrity to restrict colitis and tumourigenesis

Mengying Wei, Yongzheng Ma, Liangliang Shen, Yuqiao Xu, Lijun Liu, Xin Bu, Zhihao Guo, Hongyan Qin, Zengshan Li, Zhe Wang, Kaichun Wu, Libo Yao, Jipeng Li, Jian Zhang

EBioMedicine. 2020 Nov; 61: 103068. Published online 2020 Oct 21. doi: 10.1016/j.ebiom.2020.103068

PMCID:: PMC7581885

Abstract Article PDF–7.8M

Select item 745360011.

NDRG2 attenuates ischemia-induced astrocyte necroptosis via the repression of RIPK1

Jie Zhu, Li-Kun Yang, Qiu-Hong Wang, Wei Lin, Yi Feng, Ye-Ping Xu, Wei-Liang Chen, Kun Xiong, Yu-Hai Wang

Mol Med Rep. 2020 Oct; 22(4): 3103–3110. Published online 2020 Aug 7. doi: 10.3892/mmr.2020.11421

PMCID:: PMC7453600

Abstract Article PDF–1.2M

Select item 706774012.

NDRG2 Protects the Brain from Excitotoxicity by Facilitating Interstitial Glutamate Uptake

Anqi Yin, Hang Guo, Liang Tao, Guohong Cai, Yazhou Wang, Libo Yao, Lize Xiong, Jian Zhang, Yan Li

Transl Stroke Res. 2020; 11(2): 214–227. Published online 2019 Jun 27. doi: 10.1007/s12975-019-00708-9

PMCID:: PMC7067740

Abstract Article PDF–5.3M

Select item 697761813.

N-myc Downstream-Regulated Gene 2 (NDRG2) Promotes Bone Morphogenetic Protein 2 (BMP2)-Induced Osteoblastic Differentiation and Calcification by Janus Kinase 3 (JAK3)/Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathway

SunYu Chen, JianKun Wang, Chao Cai, Xiaoyan Xie

Med Sci Monit. 2020; 26: e918541-1–e918541-9. Published online 2020 Jan 8. doi: 10.12659/MSM.918541

Correction in:: Med Sci Monit. 2021; 27: e935672-1.

PMCID:: PMC6977618

Abstract Article PDF–2.7M

Select item 660900114.

The Serine/Threonine Kinase Ndr2 Controls Integrin Trafficking and Integrin-Dependent Neurite Growth

Kati Rehberg, Stefanie Kliche, Deniz A. Madencioglu, Marlen Thiere, Bettina Müller, Bernhard Manuel Meineke, Christian Freund, Eike Budinger, Oliver Stork

J Neurosci. 2014 Apr 9; 34(15): 5342–5354. doi: 10.1523/JNEUROSCI.2728-13.2014

PMCID:: PMC6609001

Abstract Article PDF–4.8M

Select item 653744315.

MicroRNA suppression of stress-responsive NDRG2 during dexamethasone treatment in skeletal muscle cells

Bilal A. Mir, Rabia Islam, Ming Kalanon, Aaron P. Russell, Victoria C. Foletta

BMC Mol Cell Biol. 2019; 20: 12. Published online 2019 May 28. doi: 10.1186/s12860-019-0194-3

PMCID:: PMC6537443

Abstract Article PDF–1.3M

Select item 649271416.

The pathological roles of NDRG2 in Alzheimer's disease, a study using animal models and APPwt‐overexpressed cells

Xian‐Fang Rong, Ying‐Ni Sun, Dong‐Mei Liu, Hua‐Jing Yin, Ying Peng, Shao‐Feng Xu, Ling Wang, Xiao‐Liang Wang

CNS Neurosci Ther. 2017 Aug; 23(8): 667–679. Published online 2017 Jul 2. doi: 10.1111/cns.12716

PMCID:: PMC6492714

Abstract Article PDF–1.3M

Select item 636512017.

NDR2 promotes the antiviral immune response via facilitating TRIM25-mediated RIG-I activation in macrophages

Zhiyong Liu, Cheng Wu, Yueyun Pan, Huan Liu, Xiumei Wang, Yuting Yang, Meidi Gu, Yuanyuan Zhang, Xiaojian Wang

Sci Adv. 2019 Feb; 5(2): eaav0163. Published online 2019 Feb 6. doi: 10.1126/sciadv.aav0163

PMCID:: PMC6365120

Abstract Article PDF–9.7M

Select item 629034518.

Filamin A Phosphorylation at Serine 2152 by the Serine/Threonine Kinase Ndr2 Controls TCR-Induced LFA-1 Activation in T Cells

Natalie Waldt, Anke Seifert, Yunus Emre Demiray, Eric Devroe, Benjamin E. Turk, Peter Reichardt, Charlie Mix, Annegret Reinhold, Christian Freund, Andreas J. Müller, Burkhart Schraven, Oliver Stork, Stefanie Kliche

Front Immunol. 2018; 9: 2852. Published online 2018 Dec 4. doi: 10.3389/fimmu.2018.02852

PMCID:: PMC6290345

Abstract Article PDF–2.8M

Select item 610560319.

Ndr kinases regulate retinal interneuron proliferation and homeostasis

Hélène Léger, Evelyn Santana, N. Adrian Leu, Eliot T. Smith, William A. Beltran, Gustavo D. Aguirre, Francis C. Luca

Sci Rep. 2018; 8: 12544. Published online 2018 Aug 22. doi: 10.1038/s41598-018-30492-9

PMCID:: PMC6105603

Abstract Article PDF–2.8M

Select item 583355720.

Loss of NDRG2 in liver microenvironment inhibits cancer liver metastasis by regulating tumor associate macrophages polarization

Mengyang Li, Xiaofeng Lai, Ying Zhao, Yuan Zhang, Minghui Li, Danxiu Li, Jing Kong, Yong Zhang, Pengyu Jing, Huichen Li, Hongyan Qin, Liangliang Shen, Libo Yao, Jipeng Li, Kefeng Dou, Jian Zhang

Cell Death Dis. 2018 Feb; 9(2): 248. Published online 2018 Feb 14. doi: 10.1038/s41419-018-0284-8

PMCID:: PMC5833557

Abstract Article PDF–3.1M

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