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Select item 111418681.

Lack of SPNS1 results in accumulation of lysolipids and lysosomal storage disease in mouse models

Hoa T.T. Ha, SiYi Liu, Xuan T.A. Nguyen, Linh K. Vo, Nancy C.P. Leong, Dat T. Nguyen, Shivaranjani Balamurugan, Pei Yen Lim, YaJun Wu, Eunju Seong, Toan Q. Nguyen, Jeongah Oh, Markus R. Wenk, Amaury Cazenave-Gassiot, Zuhal Yapici, Wei-Yi Ong, Margit Burmeister, Long N. Nguyen

JCI Insight. 2024 Apr 22; 9(8): e175462. Published online 2024 Mar 7. doi: 10.1172/jci.insight.175462

PMCID:: PMC11141868

Abstract Article PDF–2.8M

Select item 110146572.

A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis

Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina

J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787

PMCID:: PMC11014657

Abstract Article PDF–16M

Select item 108354613.

IGF2BP1/IMP1 Deletion Enhances a Facultative Stem Cell State via Regulation of MAP1LC3B

Louis R. Parham, Patrick A. Williams, Kay Katada, Shaneice K. Nettleford, Priya Chatterji, Kofi K. Acheampong, Charles H. Danan, Xianghui Ma, Lauren A. Simon, Kaitlyn E. Naughton, Rei Mizuno, Tatiana Karakasheva, Emily A. McMillan, Kelly A. Whelan, Donita C. Brady, Sydney M. Shaffer, Kathryn E. Hamilton

Cell Mol Gastroenterol Hepatol. 2024; 17(3): 439–451. Published online 2023 Dec 9. doi: 10.1016/j.jcmgh.2023.12.001

PMCID:: PMC10835461

Abstract Article PDF–3.1M

Select item 108125504.

ADP-Ribosylation Factor-Interacting Protein 2 Acts as a Novel Regulator of Mitophagy and Autophagy in Podocytes in Diabetic Nephropathy

Haihua Guo, Manuel Rogg, Julia Keller, Ann-Kathrin Scherzinger, Julia Jäckel, Charlotte Meyer, Alena Sammarco, Martin Helmstädter, Oliver Gorka, Olaf Groß, Christoph Schell, Wibke Bechtel-Walz

Antioxidants (Basel) 2024 Jan; 13(1): 81. Published online 2024 Jan 8. doi: 10.3390/antiox13010081

PMCID:: PMC10812550

Abstract Article PDF–25M

Select item 106860415.

LC3B is Lipidated to Large Lipid Droplets During Prolonged Starvation for Noncanonical Autophagy

Mohyeddine Omrane, Kalthoum Ben M’Barek, Alexandre Santinho, Nathan Nguyen, Shanta Nag, Thomas Melia, Abdou Rachid Thiam

Dev Cell. Author manuscript; available in PMC 2024 Jul 24.

Published in final edited form as: Dev Cell. 2023 Jul 24; 58(14): 1266–1281.e7. Published online 2023 Jun 13. doi: 10.1016/j.devcel.2023.05.009

PMCID:: PMC10686041

Abstract Article PDF–1.7M

Select item 105896736.

Impairment of serine transport across the blood–brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction

Inna Radzishevsky, Maali Odeh, Oded Bodner, Salman Zubedat, Lihi Shaulov, Maxim Litvak, Kayoko Esaki, Takeo Yoshikawa, Bella Agranovich, Wen-Hong Li, Alex Radzishevsky, Eyal Gottlieb, Avi Avital, Herman Wolosker

Proc Natl Acad Sci U S A. 2023 Oct 17; 120(42): e2302780120. Published online 2023 Oct 9. doi: 10.1073/pnas.2302780120

PMCID:: PMC10589673

Abstract Article PDF–6.8M

Select item 100954607.

Transcriptomic Changes Predict Metabolic Alterations in LC3 Associated Phagocytosis in Aged Mice

Anuradha Dhingra, John W. Tobias, Nancy J. Philp, Kathleen Boesze-Battaglia

Int J Mol Sci. 2023 Apr; 24(7): 6716. Published online 2023 Apr 4. doi: 10.3390/ijms24076716

PMCID:: PMC10095460

Abstract Article PDF–7.2M

Select item 100463258.

Immunoexpression Pattern of Autophagy Markers in Developing and Postnatal Kidneys of Dab1^−/−(yotari) Mice

Mirko Maglica, Nela Kelam, Ejazul Haque, Ilija Perutina, Anita Racetin, Natalija Filipović, Yu Katsuyama, Katarina Vukojević

Biomolecules. 2023 Mar; 13(3): 402. Published online 2023 Feb 21. doi: 10.3390/biom13030402

PMCID:: PMC10046325

Abstract Article PDF–72M

Select item 100013729.

Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in ACTN2

Sophie Broadway-Stringer, He Jiang, Kirsty Wadmore, Charlotte Hooper, Gillian Douglas, Violetta Steeples, Amar J. Azad, Evie Singer, Jasmeet S. Reyat, Frantisek Galatik, Elisabeth Ehler, Pauline Bennett, Jacinta I. Kalisch-Smith, Duncan B. Sparrow, Benjamin Davies, Kristina Djinovic-Carugo, Mathias Gautel, Hugh Watkins, Katja Gehmlich

Cells. 2023 Mar; 12(5): 721. Published online 2023 Feb 24. doi: 10.3390/cells12050721

PMCID:: PMC10001372

Abstract Article PDF–2.7M

Select item 952999010.

RIPOR2-mediated autophagy dysfunction is critical for aminoglycoside-induced hearing loss

Jinan Li, Chang Liu, Ulrich Müller, Bo Zhao

Dev Cell. Author manuscript; available in PMC 2023 Sep 26.

Published in final edited form as: Dev Cell. 2022 Sep 26; 57(18): 2204–2220.e6. Published online 2022 Sep 15. doi: 10.1016/j.devcel.2022.08.011

PMCID:: PMC9529990

Abstract Article PDF–4.4M

Select item 943472411.

Ambra1 deficiency impairs mitophagy in skeletal muscle

Lisa Gambarotto, Samuele Metti, Martina Chrisam, Cristina Cerqua, Patrizia Sabatelli, Andrea Armani, Carlo Zanon, Marianna Spizzotin, Silvia Castagnaro, Flavie Strappazzon, Paolo Grumati, Matilde Cescon, Paola Braghetta, Eva Trevisson, Francesco Cecconi, Paolo Bonaldo

J Cachexia Sarcopenia Muscle. 2022 Aug; 13(4): 2211–2224. Published online 2022 May 20. doi: 10.1002/jcsm.13010

PMCID:: PMC9434724

Abstract Article PDF–9.7M

Select item 919678212.

Increased alveolar epithelial TRAF6 via autophagy-dependent TRIM37 degradation mediates particulate matter-induced lung metastasis

Jiajun Liu, Shumin Li, Xuefeng Fei, Xi Nan, Yingying Shen, Huiqing Xiu, Stephania A. Cormier, Chaojie Lu, Chuqi Guo, Shibo Wang, Zhijian Cai, Pingli Wang

Autophagy. 2022; 18(5): 971–989. Published online 2021 Sep 15. doi: 10.1080/15548627.2021.1965421

PMCID:: PMC9196782

Abstract Article PDF–5.3M

Select item 899311913.

Mutation of SLC7A14 causes auditory neuropathy and retinitis pigmentosa mediated by lysosomal dysfunction

Kimberlee P. Giffen, Yi Li, Huizhan Liu, Xiao-Chang Zhao, Chang-Jun Zhang, Ren-Juan Shen, Tianying Wang, Amanda Janesick, Bo-Bei Chen, Shu-Sheng Gong, Bechara Kachar, Zi-Bing Jin, David Z. He

Sci Adv. 2022 Apr; 8(14): eabk0942. Published online 2022 Apr 8. doi: 10.1126/sciadv.abk0942

PMCID:: PMC8993119

Abstract Article PDF–6.6M

Select item 872660814.

CREG1 promotes lysosomal biogenesis and function

Jie Liu, Yanmei Qi, Joshua Chao, Pranav Sathuvalli, Leonard Y. Lee, Shaohua Li

Autophagy. 2021; 17(12): 4249–4265. Published online 2021 May 8. doi: 10.1080/15548627.2021.1909997

PMCID:: PMC8726608

Abstract Article PDF–9.2M

Select item 863232215.

BNIP3-dependent mitophagy promotes cytosolic localization of LC3B and metabolic homeostasis in the liver

Maya Z. Springer, Logan P. Poole, Lauren E. Drake, Althea Bock-Hughes, Michelle L Boland, Alexandra G. Smith, John Hart, Aparajita H. Chourasia, Ivan Liu, Grazyna Bozek, Kay F Macleod

Autophagy. 2021; 17(11): 3530–3546. Published online 2021 Feb 8. doi: 10.1080/15548627.2021.1877469