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Items: 1 to 20 of 257

1.
TACE inhibition: a promising therapeutic intervention against AATF‐mediated steatohepatitis to hepatocarcinogenesis
Akshatha N. Srinivas, Diwakar Suresh, Prashant M. Vishwanath, Suchitha Satish, Prasanna K. Santhekadur, Saisudha Koka, Divya P. Kumar
Mol Oncol. 2024 Aug; 18(8): 1940–1957. Published online 2024 Apr 1. doi: 10.1002/1878-0261.13646
PMCID:
PMC11306524
AbstractArticlePDF–12M
2.
Ectodomain shedding of PLA2R1 is mediated by the metalloproteases ADAM10 and ADAM17
Guillaume Dolla, Sarah Nicolas, Ligia Ramos dos Santos, Alexandre Bourgeois, Raphaëlle Pardossi-Piquard, Franck Bihl, Christelle Zaghrini, Joana Justino, Christine Payré, Pascal Mansuelle, Christoph Garbers, Pierre Ronco, Frédéric Checler, Gérard Lambeau, Agnès Petit-Paitel
J Biol Chem. 2024 Jul; 300(7): 107480. Published online 2024 Jun 17. doi: 10.1016/j.jbc.2024.107480
PMCID:
PMC11301074
AbstractArticlePDF–4.9M
3.
Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals
Fangfang Lu, Hongtu Zhao, Yaxin Dai, Yingdi Wang, Chia-Hsueh Lee, Matthew Freeman
Mol Cell. 2024 Jun 6; 84(11): 2152–2165.e5. doi: 10.1016/j.molcel.2024.04.025
PMCID:
PMC11248996
AbstractArticlePDF–6.6M
4.
Downregulation of the metalloproteinases ADAM10 or ADAM17 promotes osteoclast differentiation
Aaron Babendreyer, Julia Kieselhorst, Cindy Rinkens, Anastasia M. Lyashenko, Stefan Düsterhöft, Holger Jahr, Rogerio B. Craveiro, Michael Wolf, Andreas Ludwig
Cell Commun Signal. 2024; 22: 322. Published online 2024 Jun 11. doi: 10.1186/s12964-024-01690-y
PMCID:
PMC11167776
AbstractArticlePDF–11M
5.
Up‐regulated expression of ADAM17 in gastrointestinal stromal tumors: coexpression with EGFR and EGFR ligands
Motomichi Nakagawa, Kazuki Nabeshima, Shigeyuki Asano, Makoto Hamasaki, Noriko Uesugi, Hiroki Tani, Yuichi Yamashita, Hiroshi Iwasaki
Cancer Sci. 2009 Apr; 100(4): 654–662. Published online 2009 Mar 1. doi: 10.1111/j.1349-7006.2009.01089.x
PMCID:
PMC11158838
AbstractArticlePDF–2.1M
6.
The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9
Maria Dolores Gutiérrez-López, Alvaro Gilsanz, María Yáñez-Mó, Susana Ovalle, Esther M. Lafuente, Carmen Domínguez, Peter N. Monk, Isidoro González-Alvaro, Francisco Sánchez-Madrid, Carlos Cabañas
Cell Mol Life Sci. 2011 Oct; 68(19): 3275–3292. Published online 2011 Mar 2. doi: 10.1007/s00018-011-0639-0
PMCID:
PMC11115118
AbstractArticlePDF–1.0M
7.
Degradome of soluble ADAM10 and ADAM17 metalloproteases
Franka Scharfenberg, Andreas Helbig, Martin Sammel, Julia Benzel, Uwe Schlomann, Florian Peters, Rielana Wichert, Maximilian Bettendorff, Dirk Schmidt-Arras, Stefan Rose-John, Catherine Moali, Stefan F. Lichtenthaler, Claus U. Pietrzik, Jörg W. Bartsch, Andreas Tholey, Christoph Becker-Pauly
Cell Mol Life Sci. 2020 Jan; 77(2): 331–350. Published online 2019 Jun 17. doi: 10.1007/s00018-019-03184-4
PMCID:
PMC11105009
AbstractArticlePDF–2.2M
8.
Regulation of Mertk Surface Expression via ADAM17 and γ-Secretase Proteolytic Processing
Kevin C. Lahey, Christopher Varsanyi, Ziren Wang, Ahmed Aquib, Varsha Gadiyar, Alcina A. Rodrigues, Rachael Pulica, Samuel Desind, Viralkumar Davra, David C. Calianese, Dongfang Liu, Jong-Hyun Cho, Sergei V. Kotenko, Mariana S. De Lorenzo, Raymond B. Birge
Int J Mol Sci. 2024 Apr; 25(8): 4404. Published online 2024 Apr 17. doi: 10.3390/ijms25084404
PMCID:
PMC11050108
AbstractArticlePDF–5.9M
9.
The Important Role of Phosphatidylserine, ADAM17, TNF-Alpha, and Soluble MER on Efferocytosis Activity in Central Obesity
Chandra Agung Purnama, Anna Meiliana, Melisa Intan Barliana, Keri Lestari, Andi Wijaya
J Obes. 2024; 2024: 1424404. Published online 2024 Mar 20. doi: 10.1155/2024/1424404
PMCID:
PMC10977254
AbstractArticlePDF–782K
10.
Tumor-derived exosomal ADAM17 promotes pre-metastatic niche formation by enhancing vascular permeability in colorectal cancer
Keyu Li, Wenhua Xue, Zhihua Lu, Suo Wang, Jiayao Zheng, Kuangyi Lu, Ming Li, Yang Zong, Feng Xu, Jiamin Dai, Yang Yang, Jinbing Sun
J Exp Clin Cancer Res. 2024; 43: 59. Published online 2024 Feb 27. doi: 10.1186/s13046-024-02991-3
PMCID:
PMC10898123
AbstractArticlePDF–16M
11.
Expression of ADAM17 and its clinical value for patients with pernicious placenta previa: A retrospective study of 148 PPP patients underwent cesarean section
Xiutao Huang, Xingxing Wang, Xiang Xiao, Jin Li, Hang Yuan, Li Hou
Medicine (Baltimore) 2024 Feb 9; 103(6): e32848. Published online 2024 Feb 9. doi: 10.1097/MD.0000000000032848
PMCID:
PMC10860947
AbstractArticlePDF–532K
12.
m6A-modified HOXC10 promotes HNSCC progression via co-activation of ADAM17/EGFR and Wnt/β-catenin signaling
Yujuan Zhou, Qiang Huang, Chunping Wu, Ye Xu, Yang Guo, Xiaohui Yuan, Chengzhi Xu, Liang Zhou
Int J Oncol. 2024 Feb; 64(2): 10. Published online 2023 Dec 6. doi: 10.3892/ijo.2023.5598
PMCID:
PMC10734666
AbstractArticlePDF–13M
13.
Predictive Roles of ADAM17 in Patient Survival and Immune Cell Infiltration in Hepatocellular Carcinoma
Tianlong Ding, Yang Yu, Lei Gao, Lin Xiang, Bo Xu, Baohong Gu, Hao Chen
Int J Mol Sci. 2023 Dec; 24(23): 17069. Published online 2023 Dec 2. doi: 10.3390/ijms242317069
PMCID:
PMC10707406
AbstractArticlePDF–22M
14.
Genetic Predisposition to Elevated Levels of Circulating ADAM17 Is Associated with the Risk of Severe COVID-19
Mengyu Pan, Isabel Goncalves, Andreas Edsfeldt, Jiangming Sun, Per Swärd
Int J Mol Sci. 2023 Nov; 24(21): 15879. Published online 2023 Nov 1. doi: 10.3390/ijms242115879
PMCID:
PMC10647461
AbstractArticlePDF–763K
15.
ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways
Anzelika Rubina, Mihil Patel, Katie Nightingale, Martin Potts, Ceri A. Fielding, Simon Kollnberger, Betty Lau, Kristin Ladell, Kelly L. Miners, Jenna Nichols, Luis Nobre, Dawn Roberts, Terrence M. Trinca, Jason P. Twohig, Virginia-Maria Vlahava, Andrew J. Davison, David A. Price, Peter Tomasec, Gavin W. G. Wilkinson, Michael P. Weekes, Richard J. Stanton, Eddie C. Y. Wang
Proc Natl Acad Sci U S A. 2023 Aug 15; 120(33): e2303155120. Published online 2023 Aug 10. doi: 10.1073/pnas.2303155120
PMCID:
PMC10438378
AbstractArticlePDF–1.5M
16.
Ectodomain Shedding by ADAM17 Increases the Release of Soluble CD40 from Human Endothelial Cells under Pro-Inflammatory Conditions
Anton Klersy, Sören Meyer, Florian Leuschner, Thorsten Kessler, Markus Hecker, Andreas H. Wagner
Cells. 2023 Aug; 12(15): 1926. Published online 2023 Jul 25. doi: 10.3390/cells12151926
PMCID:
PMC10417149
AbstractArticlePDF–2.0M
17.
Investigation of CD56, ADAM17 and FGF21 Expressions in the Placentas of Preeclampsia Cases
Irem Darka Aslan, Gorker Sel, Figen Barut, Rabia Baser Acikgoz, Sibel Balci, Ulku Ozmen, Aykut Barut, Muge Harma, Mehmet Ibrahim Harma
Medicina (Kaunas) 2023 Jun; 59(6): 1145. Published online 2023 Jun 14. doi: 10.3390/medicina59061145
PMCID:
PMC10302637
AbstractArticlePDF–3.3M
18.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
19.
ADAM17 Confers Temozolomide Resistance in Human Glioblastoma Cells and miR-145 Regulates Its Expression
Jen-Tsung Yang, I-Neng Lee, Cheng Huang, Hsiu-Chen Huang, Yu-Ping Wu, Zhi-Yong Chong, Jui-Chieh Chen
Int J Mol Sci. 2023 May; 24(9): 7703. Published online 2023 Apr 22. doi: 10.3390/ijms24097703
PMCID:
PMC10178422
AbstractArticlePDF–5.8M
20.
ADAM10 and ADAM17, Major Regulators of Chronic Kidney Disease Induced Atherosclerosis?
Sanne L. Maas, Marjo M. P. C. Donners, Emiel P. C. van der Vorst
Int J Mol Sci. 2023 Apr; 24(8): 7309. Published online 2023 Apr 15. doi: 10.3390/ijms24087309
PMCID:
PMC10139114
AbstractArticlePDF–2.1M

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