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Select item 112908531.

Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling

Kaleeckal G. Harikumar, Peishen Zhao, Brian P. Cary, Xiaomeng Xu, Aditya J. Desai, Maoqing Dong, Jesse I. Mobbs, Chirine Toufaily, Sebastian G. B. Furness, Arthur Christopoulos, Matthew J. Belousoff, Denise Wootten, Patrick M. Sexton, Laurence J. Miller

PLoS Biol. 2024 Jul; 22(7): e3002673. Published online 2024 Jul 31. doi: 10.1371/journal.pbio.3002673

PMCID:: PMC11290853

Abstract Article PDF–3.4M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 67197003.

MOLECULAR CLONING OF THE HUMAN BRAIN AND GASTRIC CHOLECYSTOKININ RECEPTOR: STRUCTURE, FUNCTIONAL EXPRESSION AND CHROMOSOMAL LOCALIZATION

Joseph R. Pisegna, Andreas de Weerth, Konrad Huppi, Stephen A. Wank

Biochem Biophys Res Commun. Author manuscript; available in PMC 2019 Sep 3.

Published in final edited form as: Biochem Biophys Res Commun. 1992 Nov 30; 189(1): 296–303. doi: 10.1016/0006-291x(92)91557-7

PMCID:: PMC6719700

Abstract Article PDF–1.3M

Select item 60972854.

Low serum gastrin associated with ER⁺ breast cancer development via inactivation of CCKBR/ERK/P65 signaling

Li-Li Meng, Jing-Long Wang, Shu-Ping Xu, Li-Dong Zu, Zhao-Wen Yan, Jian-Bing Zhang, Ya-Qin Han, Guo-Hui Fu

BMC Cancer. 2018; 18: 824. Published online 2018 Aug 16. doi: 10.1186/s12885-018-4717-7

PMCID:: PMC6097285

Abstract Article PDF–9.8M

Select item 57753875.

Expression of the Cholecystokinin-B Receptor in Neoplastic Gastric Cells

Patricia Mjønes, Ivar S. Nordrum, Øystein Sørdal, Liv Sagatun, Reidar Fossmark, Arne Sandvik, Helge L. Waldum

Horm Cancer. 2018 Feb; 9(1): 40–54. Published online 2017 Oct 4. doi: 10.1007/s12672-017-0311-8

PMCID:: PMC5775387

Abstract Article PDF–3.0M

Select item 55316116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 53717307.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 49825988.

MiR-148a Functions as a Tumor Suppressor by Targeting CCK-BR via Inactivating STAT3 and Akt in Human Gastric Cancer

Beiqin Yu, Xin Lv, Liping Su, Jianfang Li, Yingyan Yu, Qinlong Gu, Min Yan, Zhenggang Zhu, Bingya Liu

PLoS One. 2016; 11(8): e0158961. Published online 2016 Aug 12. doi: 10.1371/journal.pone.0158961

PMCID:: PMC4982598

Abstract Article PDF–8.7M

Select item 49247389.

Assessment of cholecystokinin 2 receptor (CCK2R) in neoplastic tissue

Jyoti Roy, Karson S. Putt, Domenico Coppola, Marino E. Leon, Farah K. Khalil, Barbara A. Centeno, Noel Clark, Valerie E. Stark, David L. Morse, Philip S. Low

Oncotarget. 2016 Mar 22; 7(12): 14605–14615. Published online 2016 Feb 20. doi: 10.18632/oncotarget.7522

PMCID:: PMC4924738

Abstract Article PDF–3.3M

Select item 478320710.

A Common CCK-B Receptor Intronic Variant in Pancreatic Adenocarcinoma in a Hungarian Cohort

Anita Balázs, Balázs Csaba Németh, Balázs Ördög, Eszter Hegyi, István Hritz, László Czakó, József Czimmer, Szilárd Gódi, Adrienn Csiszkó, Zoltán Rakonczay, Jr., Andrea Párniczky, Ferenc Izbéki, Adrienn Halász, Zsuzsanna Kahán, Péter Hegyi, Miklós Sahin-Tóth

Pancreas. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Pancreas. 2016 May; 45(4): 541–545. doi: 10.1097/MPA.0000000000000539

PMCID:: PMC4783207

Abstract Article PDF–960K

Select item 472790011.

Variants near CCK receptors are associated with electrophysiological responses to prepulse startle stimuli in a Mexican American cohort

Trina M. Norden-Krichmar, Ian R. Gizer, Evelyn Phillips, Kirk C. Wilhelmsen, Nicholas J. Schork, Cindy L. Ehlers

Twin Res Hum Genet. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: Twin Res Hum Genet. 2015 Dec; 18(6): 727–737. Published online 2015 Nov 26. doi: 10.1017/thg.2015.77

PMCID:: PMC4727900

Abstract Article PDF–912K

Select item 472701512.

Coexpression of cholecystokinin-B/gastrin receptor and gastrin gene in human gastric tissues and gastric cancer cell line

Jian-Jiang Zhou, Man-Ling Chen, Qun-Zhou Zhang, Jian-Kun Hu, Wen-Ling Wang

World J Gastroenterol. 2004 Mar 15; 10(6): 791–794. Published online 2004 Mar 15. doi: 10.3748/wjg.v10.i6.791

PMCID:: PMC4727015

Abstract Article PDF–104K

Select item 439832013.

Functional Synergy between Cholecystokinin Receptors CCKAR and CCKBR in Mammalian Brain Development

Sayoko Nishimura, Kaya Bilgüvar, Keiko Ishigame, Nenad Sestan, Murat Günel, Angeliki Louvi

PLoS One. 2015; 10(4): e0124295. Published online 2015 Apr 15. doi: 10.1371/journal.pone.0124295

PMCID:: PMC4398320

Abstract Article PDF–29M

Select item 432654914.

DISTRIBUTION OF CCK-B RECEPTOR GENOTYPE BETWEEN PANCREATIC CANCER PATIENTS AND CONTROLS AND ITS IMPACT ON SURVIVAL

Jill P. Smith, David C. Whitcomb, Gail L. Matters, Randall E. Brand, Jiangang Liao, Yu-Jing Huang, Marsha L. Frazier

Pancreas. Author manuscript; available in PMC 2016 Mar 1.

Published in final edited form as: Pancreas. 2015 Mar; 44(2): 236–242. doi: 10.1097/MPA.0000000000000263

PMCID:: PMC4326549

Abstract Article PDF–436K

Select item 426658815.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 407399016.

Cholecystokinin and pancreatic cancer: the chicken or the egg?

Jill P. Smith, Travis E. Solomon

Am J Physiol Gastrointest Liver Physiol. 2014 Jan 15; 306(2): G91–G101. Published online 2013 Oct 31. doi: 10.1152/ajpgi.00301.2013

PMCID:: PMC4073990

Abstract Article

Select item 395169117.

Prefrontal Cortical Circuit for Depression- and Anxiety-Related Behaviors Mediated by Cholecystokinin: Role of ΔFosB

Vincent Vialou, Rosemary C. Bagot, Michael E. Cahill, Deveroux Ferguson, Alfred J. Robison, David M. Dietz, Barbara Fallon, Michelle Mazei-Robison, Stacy M. Ku, Eileen Harrigan, Catherine A. Winstanley, Tej Joshi, Jian Feng, Olivier Berton, Eric J. Nestler

J Neurosci. 2014 Mar 12; 34(11): 3878–3887. doi: 10.1523/JNEUROSCI.1787-13.2014

PMCID:: PMC3951691

Abstract Article PDF–1.4M

Select item 390477318.

Somatic Mutations in CCK2R Alter Receptor Activity that Promote Oncogenic Phenotypes

Melinda D. Willard, Mary E. Lajiness, Isabella H. Wulur, Bo Feng, Michelle L. Swearingen, Mark T. Uhlik, Kenneth W. Kinzler, Victor E. Velculescu, Tobias Sjöblom, Sanford D. Markowitz, Steven M. Powell, Bert Vogelstein, Thomas D. Barber

Mol Cancer Res. Author manuscript; available in PMC 2014 Jan 28.

Published in final edited form as: Mol Cancer Res. 2012 Jun; 10(6): 739–749. Published online 2012 Apr 19. doi: 10.1158/1541-7786.MCR-11-0483

PMCID:: PMC3904773

Abstract Article PDF–2.6M

Select item 341237819.

Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity

Marija Usenovic, Adam L. Knight, Arpita Ray, Victoria Wong, Kevin R. Brown, Guy A. Caldwell, Kim A. Caldwell, Igor Stagljar, Dimitri Krainc

Hum Mol Genet. 2012 Sep 1; 21(17): 3785–3794. Published online 2012 May 29. doi: 10.1093/hmg/dds206

PMCID:: PMC3412378

Abstract Article PDF–534K

Select item 337816720.

Downregulation of the CCK-B receptor in pancreatic cancer cells blocks proliferation and promotes apoptosis

Kristin K. Fino, Gail L. Matters, Christopher O. McGovern, Evan L. Gilius, Jill P. Smith

Am J Physiol Gastrointest Liver Physiol. 2012 Jun 1; 302(11): G1244–G1252. Published online 2012 Mar 22. doi: 10.1152/ajpgi.00460.2011

PMCID:: PMC3378167

Abstract Article

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