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Items: 1 to 20 of 59

1.
Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein
Xiao Tang, Yang Liu, Jinhui Wang, Teng Long, Bobo Wing Yee Mok, Yan Huang, Ziqing Peng, Qinyu Jia, Chengxi Liu, Pui-Kin So, Sirius Pui-Kam Tse, Cheuk Hei NG, Shiyi Liu, Fei Sun, Shaojun Tang, Zhong-Ping Yao, Honglin Chen, Yusong Guo
J Biol Chem. 2024 Jun; 300(6): 107390. Published online 2024 May 21. doi: 10.1016/j.jbc.2024.107390
PMCID:
PMC11237930
AbstractArticlePDF–3.8M
2.
MCM8 promotes gastric cancer progression through RPS15A and predicts poor prognosis
Lixian Ding, Mingjun Sun, Yanyan Sun, Jinxing Li, Zhicheng Zhang, Shuwei Dang, Jinning Zhang, Bang Yang, Youlin Dai, Qinghao Zhou, Dazhi Zhou, Encheng Li, Shuqi Peng, Guodong Li
Cancer Med. 2024 Jul; 13(13): e7424. Published online 2024 Jul 10. doi: 10.1002/cam4.7424
PMCID:
PMC11236911
AbstractArticlePDF–56M
3.
MCM8 promotes lung cancer progression through upregulating DNAJC10
Lei Cao, Hongsheng Liu, Zhijun Han, Cheng Huang, Chao Guo, Luo Zhao, Chao Gao, Yuan Xu, Guige Wang, Zhe Feng, Shanqing Li
J Cell Mol Med. 2024 Jun; 28(12): e18488. Published online 2024 Jun 21. doi: 10.1111/jcmm.18488
PMCID:
PMC11190951
AbstractArticlePDF–9.7M
4.
Mechanism of DNA unwinding by MCM8-9 in complex with HROB
Ananya Acharya, Hélène Bret, Jen-Wei Huang, Martin Mütze, Martin Göse, Vera Maria Kissling, Ralf Seidel, Alberto Ciccia, Raphaël Guérois, Petr Cejka
Nat Commun. 2024; 15: 3584. Published online 2024 Apr 27. doi: 10.1038/s41467-024-47936-8
PMCID:
PMC11055865
AbstractArticlePDF–4.9M
5.
Activity, substrate preference and structure of the HsMCM8/9 helicase
David R McKinzey, Chuxuan Li, Yang Gao, Michael A Trakselis
Nucleic Acids Res. 2023 Aug 11; 51(14): 7330–7341. Published online 2023 Jun 13. doi: 10.1093/nar/gkad508
PMCID:
PMC10415141
AbstractArticlePDF–1.8M
6.
Enhancer-driven transcription of MCM8 by E2F4 promotes ATR pathway activation and glioma stem cell characteristics
Yu-meng Sun, Yi-meng Zhang, Hai-liang Shi, Song Yang, Yin-long Zhao, Hong-jiang Liu, Chen Li, Hong-lei Liu, Ji-peng Yang, Jian Song, Guo-zhu Sun, Jian-kai Yang
Hereditas. 2023; 160: 29. Published online 2023 Jun 22. doi: 10.1186/s41065-023-00292-x
PMCID:
PMC10286446
AbstractArticlePDF–5.3M
7.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
8.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
9.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
10.
Knockdown of MCM8 functions as a strategy to inhibit the development and progression of osteosarcoma through regulating CTGF
Zhinan Ren, Jun Li, Shanwen Zhao, Qi Qiao, Runguang Li
Cell Death Dis. 2021 Apr; 12(4): 376. Published online 2021 Apr 7. doi: 10.1038/s41419-021-03621-y
PMCID:
PMC8027380
AbstractArticlePDF–3.4M
11.
Identification of mini‐chromosome maintenance 8 as a potential prognostic marker and its effects on proliferation and apoptosis in gastric cancer
Bin Huang, Minghe Lin, Lisha Lu, Wujin Chen, Jingzhuang Tan, Jinyan Zhao, Zhiyun Cao, Xiaoqin Zhu, Jiumao Lin
J Cell Mol Med. 2020 Dec; 24(24): 14415–14425. Published online 2020 Nov 6. doi: 10.1111/jcmm.16062
PMCID:
PMC7753872
AbstractArticlePDF–2.2M
12.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
13.
Germline biallelic Mcm8 variants are associated with early-onset Lynch-like syndrome
Mariano Golubicki, Laia Bonjoch, José G. Acuña-Ochoa, Marcos Díaz-Gay, Jenifer Muñoz, Miriam Cuatrecasas, Teresa Ocaña, Soledad Iseas, Guillermo Mendez, Daniel Cisterna, Stephanie A. Schubert, Maartje Nielsen, Tom van Wezel, Yael Goldberg, Eli Pikarsky, Juan Robbio, Enrique Roca, Antoni Castells, Francesc Balaguer, Marina Antelo, Sergi Castellví-Bel
JCI Insight. 2020 Sep 17; 5(18): e140698. Published online 2020 Sep 17. doi: 10.1172/jci.insight.140698
PMCID:
PMC7526538
AbstractArticlePDF–20M
14.
Two novel mutations in the MCM8 gene shared by two Chinese siblings with primary ovarian insufficiency and short stature
Fei Wang, Sheng Guo, Pin Li
Mol Genet Genomic Med. 2020 Sep; 8(9): e1396. Published online 2020 Jul 11. doi: 10.1002/mgg3.1396
PMCID:
PMC7507566
AbstractArticlePDF–1.2M
15.
MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage
Jen-Wei Huang, Ananya Acharya, Angelo Taglialatela, Tarun S. Nambiar, Raquel Cuella-Martin, Giuseppe Leuzzi, Samuel B. Hayward, Sarah A. Joseph, Gregory J. Brunette, Roopesh Anand, Rajesh K. Soni, Nathan L. Clark, Kara A. Bernstein, Petr Cejka, Alberto Ciccia
Nat Commun. 2020; 11: 2948. Published online 2020 Jun 11. doi: 10.1038/s41467-020-16718-3
PMCID:
PMC7290032
AbstractArticlePDF–3.0M
16.
Novel loss‐of‐function mutation in MCM8 causes premature ovarian insufficiency
Ya‐Xin Zhang, Wen‐Bin He, Wen‐Juan Xiao, Lan‐Lan Meng, Chen Tan, Juan Du, Guang‐Xiu Lu, Ge Lin, Yue‐Qiu Tan
Mol Genet Genomic Med. 2020 Apr; 8(4): e1165. Published online 2020 Feb 11. doi: 10.1002/mgg3.1165
PMCID:
PMC7196458
AbstractArticlePDF–838K
17.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
18.
Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity
Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller
Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119
PMCID:
PMC6942044
AbstractArticlePDF–10M
19.
Control of homologous recombination by the HROB–MCM8–MCM9 pathway
Nicole Hustedt, Yuichiro Saito, Michal Zimmermann, Alejandro Álvarez-Quilón, Dheva Setiaputra, Salomé Adam, Andrea McEwan, Jing Yi Yuan, Michele Olivieri, Yichao Zhao, Masato T. Kanemaki, Andrea Jurisicova, Daniel Durocher
Genes Dev. 2019 Oct 1; 33(19-20): 1397–1415. doi: 10.1101/gad.329508.119
PMCID:
PMC6771392
AbstractArticlePDF–6.3M
20.
Genome-wide investigation of the clinical significance and prospective molecular mechanism of minichromosome maintenance protein family genes in patients with Lung Adenocarcinoma
Kang Liu, Min Kang, Xiwen Liao, Rensheng Wang
PLoS One. 2019; 14(7): e0219467. Published online 2019 Jul 19. doi: 10.1371/journal.pone.0219467
PMCID:
PMC6641114
AbstractArticlePDF–9.2M

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