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Items: 1 to 20 of 83

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Ncoa2 promotes CD8+ T cell-mediated anti-tumor immunity by stimulating T-cell activation via upregulation of PGC-1α critical for mitochondrial function: Noca2 in CD8+ T-cell activation and antitumor response
Xiancai Zhong, Hongmin Wu, Ching Ouyang, Wencan Zhang, Yun Shi, Yi-Chang Wang, David K. Ann, Yousang Gwack, Weirong Shang, Zuoming Sun
Cancer Immunol Res. Author manuscript; available in PMC 2024 Apr 4.
Published in final edited form as: Cancer Immunol Res. 2023 Oct 4; 11(10): 1414–1431. doi: 10.1158/2326-6066.CIR-23-0092
PMCID:
PMC10592187
AbstractArticlePDF–2.4M
3.
HEY1-NCOA2 expression modulates chondrogenic differentiation and induces mesenchymal chondrosarcoma in mice
Miwa Tanaka, Mizuki Homme, Yasuyo Teramura, Kohei Kumegawa, Yukari Yamazaki, Kyoko Yamashita, Motomi Osato, Reo Maruyama, Takuro Nakamura
JCI Insight. 2023 May 22; 8(10): e160279. Published online 2023 May 22. doi: 10.1172/jci.insight.160279
PMCID:
PMC10322689
AbstractArticlePDF–16M
4.
SRC2 controls CD4+ T cell activation via stimulating c-Myc-mediated upregulation of amino acid transporter Slc7a5
Wencan Zhang, Xu Cao, Xiancai Zhong, Hongmin Wu, Yun Shi, Mingye Feng, Yi-Chang Wang, David Ann, Yousang Gwack, Yate-Ching Yuan, Weirong Shang, Zuoming Sun
Proc Natl Acad Sci U S A. 2023 May 2; 120(18): e2221352120. Published online 2023 Apr 24. doi: 10.1073/pnas.2221352120
PMCID:
PMC10160970
AbstractArticlePDF–2.6M
5.
Hypothalamic steroid receptor coactivator-2 regulates adaptations to fasting and overnutrition
Yongjie Yang, Yanlin He, Hailan Liu, Wenjun Zhou, Chunmei Wang, Pingwen Xu, Xing Cai, Hesong Liu, Kaifan Yu, Zhou Pei, Ilirjana Hyseni, Makoto Fukuda, Qingchun Tong, Jianming Xu, Zheng Sun, Bert W. O’Malley, Yong Xu
Cell Rep. Author manuscript; available in PMC 2021 Dec 29.
Published in final edited form as: Cell Rep. 2021 Dec 7; 37(10): 110075. doi: 10.1016/j.celrep.2021.110075
PMCID:
PMC8715676
AbstractArticlePDF–1.5M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
Transcription cofactor GRIP1 differentially affects myeloid cell–driven neuroinflammation and response to IFN-β therapy
Sanda Mimouna, David A. Rollins, Gayathri Shibu, Bowranigan Tharmalingam, Dinesh K. Deochand, Xi Chen, David Oliver, Yurii Chinenov, Inez Rogatsky
J Exp Med. 2021 Jan 4; 218(1): e20192386. Published online 2020 Oct 12. doi: 10.1084/jem.20192386
Correction in:
J Exp Med. 2021 Jan 4; 218(1): jem.2019238611162020C.
PMCID:
PMC7555412
AbstractArticlePDF–5.7M
8.
SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα
Shoshana Naiman, Frank K. Huynh, Reuven Gil, Yair Glick, Yael Shahar, Noga Touitou, Liat Nahum, Matan Y. Avivi, Asael Roichman, Yariv Kanfi, Asaf A. Gertler, Tirza Doniger, Olga R. Ilkayeva, Ifat Abramovich, Orly Yaron, Batia Lerrer, Eyal Gottlieb, Robert A. Harris, Doron Gerber, Matthew D. Hirschey, Haim Y. Cohen
Cell Rep. Author manuscript; available in PMC 2020 Apr 18.
Published in final edited form as: Cell Rep. 2019 Dec 17; 29(12): 4127–4143.e8. doi: 10.1016/j.celrep.2019.11.067
PMCID:
PMC7165364
AbstractArticlePDF–2.3M
9.
SRC-1 Null Mice Exhibit Moderate Motor Dysfunction and Delayed Development of Cerebellar Purkinje Cells
Eijun Nishihara, Hiromi Yoshida-Komiya, Chi-Shing Chan, Lan Liao, Ronald L. Davis, Bert W. O'Malley, Jianming Xu
J Neurosci. 2003 Jan 1; 23(1): 213–222. doi: 10.1523/JNEUROSCI.23-01-00213.2003
PMCID:
PMC6742154
AbstractArticlePDF–641K
10.
Transient activation of AMPK preceding left ventricular pressure overload reduces adverse remodeling and preserves left ventricular function
Deok Hwa Nam, Eunah Kim, Ashley Benham, Hye-Kyung Park, Benjamin Soibam, George E. Taffet, Jason T. Kaelber, Ji Ho Suh, Heinrich Taegtmeyer, Mark L. Entman, Erin L. Reineke
FASEB J. 2019 Jan; 33(1): 711–721. Published online 2018 Jul 19. doi: 10.1096/fj.201800602R
PMCID:
PMC6355077
AbstractArticle
11.
Steroid receptor coactivator-2 (SRC-2) coordinates cardiomyocyte paracrine signaling to promote pressure overload–induced angiogenesis
Ji Ho Suh, Li Lai, Deokhwa Nam, Jong Kim, Juyeon Jo, George E. Taffet, Eunah Kim, Jason T. Kaelber, Hyun-Kyoung Lee, Mark L. Entman, John P. Cooke, Erin L. Reineke
J Biol Chem. 2017 Dec 29; 292(52): 21643–21652. Published online 2017 Nov 10. doi: 10.1074/jbc.M117.804740
PMCID:
PMC5766961
AbstractArticlePDF–2.4M
12.
Phylogenetic and expression analysis of the basic helix-loop-helix transcription factor gene family: genomic approach to cellular differentiation
Jeffrey D. Stevens, Eric H. Roalson, Michael K. Skinner
Differentiation. Author manuscript; available in PMC 2017 Dec 13.
Published in final edited form as: Differentiation. 2008 Nov; 76(9): 1006–1022. Published online 2008 Jun 4. doi: 10.1111/j.1432-0436.2008.00285.x
PMCID:
PMC5728086
AbstractArticlePDF–2.4M
13.
Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages
David A. Rollins, Joubert B. Kharlyngdoh, Maddalena Coppo, Bowranigan Tharmalingam, Sanda Mimouna, Ziyi Guo, Maria A. Sacta, Miles A. Pufall, Robert P. Fisher, Xiaoyu Hu, Yurii Chinenov, Inez Rogatsky
Nat Commun. 2017; 8: 1739. Published online 2017 Nov 23. doi: 10.1038/s41467-017-01569-2
PMCID:
PMC5700924
AbstractArticlePDF–2.4M
14.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
15.
SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer
Shruthy Suresh, Deniz Durakoglugil, Xiaorong Zhou, Bokai Zhu, Sarah A. Comerford, Chao Xing, Xian-Jin Xie, Brian York, Kathryn A. O’Donnell
PLoS Genet. 2017 Mar; 13(3): e1006650. Published online 2017 Mar 8. doi: 10.1371/journal.pgen.1006650
Correction in:
PLoS Genet. 2018 Apr; 14(4): e1007344.
PMCID:
PMC5362238
AbstractArticlePDF–3.3M
16.
Genetic and Environmental Models of Circadian Disruption Link SRC-2 Function to Hepatic Pathology
Tiffany Fleet, Erin Stashi, Bokai Zhu, Kimal Rajapakshe, Kathrina L. Marcelo, Nicole M. Kettner, Blythe K. Gorman, Cristian Coarfa, Loning Fu, Bert W. O’Malley, Brian York
J Biol Rhythms. Author manuscript; available in PMC 2017 Jan 20.
Published in final edited form as: J Biol Rhythms. 2016 Oct; 31(5): 443–460. Published online 2016 Jul 17. doi: 10.1177/0748730416657921
PMCID:
PMC5248931
AbstractArticlePDF–2.7M
17.
The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis
Maddalena Coppo, Yurii Chinenov, Maria A. Sacta, Inez Rogatsky
Nat Commun. 2016; 7: 12254. Published online 2016 Jul 28. doi: 10.1038/ncomms12254
PMCID:
PMC4974480
AbstractArticlePDF–1.4M
18.
Expression of the MOZ-TIF2 oncoprotein in mice represses senescence
Anne Largeot, Flor Maria Perez-Campo, Elli Marinopoulou, Michael Lie-a-Ling, Valerie Kouskoff, Georges Lacaud
Exp Hematol. 2016 Apr; 44(4): 231–237.e4. doi: 10.1016/j.exphem.2015.12.006
PMCID:
PMC4819447
AbstractArticle
19.
Coactivator-Dependent Oscillation of Chromatin Accessibility Dictates Circadian Gene Amplitude via REV-ERB Loading
Bokai Zhu, Leah A. Gates, Erin Stashi, Subhamoy Dasgupta, Naomi Gonzales, Adam Dean, Clifford C. Dacso, Brian York, Bert W. O’Malley
Mol Cell. Author manuscript; available in PMC 2016 Dec 3.
Published in final edited form as: Mol Cell. 2015 Dec 3; 60(5): 769–783. Published online 2015 Nov 21. doi: 10.1016/j.molcel.2015.10.024
PMCID:
PMC4671835
AbstractArticlePDF–3.4M
20.
SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis
Tiffany Fleet, Bin Zhang, Fumin Lin, Bokai Zhu, Subhamoy Dasgupta, Erin Stashi, Bryan Tackett, Sundararajah Thevananther, Kimal I. Rajapakshe, Naomi Gonzales, Adam Dean, Jianqiang Mao, Nikolai Timchenko, Anna Malovannaya, Jun Qin, Cristian Coarfa, Francesco DeMayo, Clifford C. Dacso, Charles E. Foulds, Bert W. O’Malley, Brian York
Proc Natl Acad Sci U S A. 2015 Nov 3; 112(44): E6068–E6077. Published online 2015 Oct 20. doi: 10.1073/pnas.1519073112
PMCID:
PMC4640775
AbstractArticlePDF–3.0M

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