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Items: 1 to 20 of 80

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Sortilin deletion in the prefrontal cortex and hippocampus ameliorates depressive-like behaviors in mice via regulating ASM/ceramide signaling
Shu-jian Chen, Cong-cong Gao, Qun-yu Lv, Meng-qi Zhao, Xiao-ying Qin, Hong Liao
Acta Pharmacol Sin. 2022 Aug; 43(8): 1940–1954. Published online 2021 Dec 20. doi: 10.1038/s41401-021-00823-0
PMCID:
PMC9343424
AbstractArticlePDF–6.3M
3.
Sortilin enhances secretion of apolipoprotein(a) through effects on apolipoprotein B secretion and promotes uptake of lipoprotein(a)
Justin R. Clark, Matthew Gemin, Amer Youssef, Santica M. Marcovina, Annik Prat, Nabil G. Seidah, Robert A. Hegele, Michael B. Boffa, Marlys L. Koschinsky
J Lipid Res. 2022 Jun; 63(6): 100216. Published online 2022 Apr 22. doi: 10.1016/j.jlr.2022.100216
PMCID:
PMC9131257
AbstractArticlePDF–3.8M
4.
Targeting the ASMase/S1P pathway protects from sortilin-evoked vascular damage in hypertension
Paola Di Pietro, Albino Carrizzo, Eduardo Sommella, Marco Oliveti, Licia Iacoviello, Augusto Di Castelnuovo, Fausto Acernese, Antonio Damato, Massimiliano De Lucia, Fabrizio Merciai, Paola Iesu, Eleonora Venturini, Raffaele Izzo, Valentina Trimarco, Michele Ciccarelli, Giuseppe Giugliano, Roberto Carnevale, Vittoria Cammisotto, Serena Migliarino, Nicola Virtuoso, Andrea Strianese, Viviana Izzo, Pietro Campiglia, Elena Ciaglia, Bodo Levkau, Annibale A. Puca, Carmine Vecchione
J Clin Invest. 2022 Feb 1; 132(3): e146343. Published online 2022 Feb 1. doi: 10.1172/JCI146343
PMCID:
PMC8803332
AbstractArticlePDF–1.6M
5.
ApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling
Antonino Asaro, Rishabhdev Sinha, Magda Bakun, Oleksandra Kalnytska, Anne-Sophie Carlo-Spiewok, Tymon Rubel, Annemieke Rozeboom, Michal Dadlez, Bozena Kaminska, Eleonora Aronica, Anna R. Malik, Thomas E. Willnow
J Cell Sci. 2021 Oct 15; 134(20): jcs258894. Published online 2021 Oct 21. doi: 10.1242/jcs.258894
PMCID:
PMC8572006
AbstractArticle
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
Identification of Sortilin Alternatively Spliced Variants in Mouse 3T3L1 Adipocytes
Ashley Lui, Robert Sparks, Rekha Patel, Niketa A. Patel
Int J Mol Sci. 2021 Feb; 22(3): 983. Published online 2021 Jan 20. doi: 10.3390/ijms22030983
PMCID:
PMC7863940
AbstractArticlePDF–2.9M
8.
PCBP2 post‐transcriptionally regulates sortilin expression by binding to a C‐rich element in its 3′ UTR
Toshiki Yabe‐Wada, Caroline C. Philpott, Nobuyuki Onai
FEBS Open Bio. 2020 Mar; 10(3): 407–413. Published online 2020 Feb 3. doi: 10.1002/2211-5463.12794
PMCID:
PMC7050257
AbstractArticlePDF–1.0M
9.
PAK Kinases Target Sortilin and Modulate Its Sorting
Lone Tjener Pallesen, Camilla Gustafsen, Jacob Flyvholm Cramer, Steen Vang Petersen, Søren Skou Thirup, Peder Madsen, Claus Munck Petersen
Mol Cell Biol. 2020 Feb; 40(3): e00411-19. Prepublished online 2019 Nov 25. Published online 2020 Jan 16. doi: 10.1128/MCB.00411-19
PMCID:
PMC6965034
AbstractArticlePDF–2.1M
10.
The Loop Diuretic Bumetanide Blocks Posttraumatic p75NTR Upregulation and Rescues Injured Neurons
Anastasia Shulga, Ana Cathia Magalhães, Henri Autio, Stefan Plantman, Antonio di Lieto, Anders Nykjær, Thomas Carlstedt, Mårten Risling, Urmas Arumäe, Eero Castrén, Claudio Rivera
J Neurosci. 2012 Feb 1; 32(5): 1757–1770. doi: 10.1523/JNEUROSCI.3282-11.2012
PMCID:
PMC6703341
AbstractArticlePDF–3.2M
11.
WDFY4 is required for cross-presentation in response to viral and tumor antigens
Derek J. Theisen, Jesse T. Davidson, IV, Carlos G. Briseño, Marco Gargaro, Elvin J. Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R. Brickner, Wandy L. Beatty, Herbert W. Virgin, William E. Gillanders, Nima Mosammaparast, Michael S. Diamond, L. David Sibley, Wayne Yokoyama, Robert D. Schreiber, Theresa L. Murphy, Kenneth M. Murphy
Science. Author manuscript; available in PMC 2019 Jul 24.
Published in final edited form as: Science. 2018 Nov 9; 362(6415): 694–699. doi: 10.1126/science.aat5030
PMCID:
PMC6655551
AbstractArticlePDF–1020K
12.
Tlx1/3 and Ptf1a Control the Expression of Distinct Sets of Transmitter and Peptide Receptor Genes in the Developing Dorsal Spinal Cord
Zhen Guo, Congling Zhao, Menggui Huang, Tianwen Huang, Mingran Fan, Zhiqin Xie, Ying Chen, Xiaolin Zhao, Guannan Xia, Junlan Geng, Leping Cheng
J Neurosci. 2012 Jun 20; 32(25): 8509–8520. doi: 10.1523/JNEUROSCI.6301-11.2012
PMCID:
PMC6620993
AbstractArticlePDF–5.6M
13.
Sortilin and SorLA Display Distinct Roles in Processing and Trafficking of Amyloid Precursor Protein
Camilla Gustafsen, Simon Glerup, Lone Tjener Pallesen, Ditte Olsen, Olav M. Andersen, Anders Nykjær, Peder Madsen, Claus Munck Petersen
J Neurosci. 2013 Jan 2; 33(1): 64–71. doi: 10.1523/JNEUROSCI.2371-12.2013
PMCID:
PMC6618638
AbstractArticlePDF–1.9M
14.
Hepatocyte sortilin 1 knockout and treatment with a sortilin 1 inhibitor reduced plasma cholesterol in Western diet-fed mice
Cheng Chen, Jibiao Li, David J. Matye, Yifeng Wang, Tiangang Li
J Lipid Res. 2019 Mar; 60(3): 539–549. Published online 2019 Jan 22. doi: 10.1194/jlr.M089789
PMCID:
PMC6399493
AbstractArticlePDF–1.7M
15.
Parkin mediates the ubiquitination of VPS35 and modulates retromer-dependent endosomal sorting
Erin T Williams, Liliane Glauser, Elpida Tsika, Haisong Jiang, Shariful Islam, Darren J Moore
Hum Mol Genet. 2018 Sep 15; 27(18): 3189–3205. Published online 2018 Jun 11. doi: 10.1093/hmg/ddy224
PMCID:
PMC6121197
AbstractArticlePDF–2.4M
16.
Transcriptional control of intestinal cholesterol absorption, adipose energy expenditure and lipid handling by Sortilin
Sumihiko Hagita, Maximillian A. Rogers, Tan Pham, Jennifer R. Wen, Andrew K. Mlynarchik, Masanori Aikawa, Elena Aikawa
Sci Rep. 2018; 8: 9006. Published online 2018 Jun 13. doi: 10.1038/s41598-018-27416-y
PMCID:
PMC5998044
AbstractArticlePDF–2.2M
17.
Transient denervation of viable myocardium after myocardial infarction does not alter arrhythmia susceptibility
Diana C. Parrish, Samantha D. Francis Stuart, Antoinette Olivas, Lianguo Wang, Anders Nykjaer, Crystal M. Ripplinger, Beth A. Habecker
Am J Physiol Heart Circ Physiol. 2018 Mar 1; 314(3): H415–H423. Published online 2017 Nov 3. doi: 10.1152/ajpheart.00300.2017
PMCID:
PMC5899257
AbstractArticle
18.
Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release
Nadia Leloup, Philip Lössl, Dimphna H. Meijer, Martha Brennich, Albert J. R. Heck, Dominique M. E. Thies-Weesie, Bert J. C. Janssen
Nat Commun. 2017; 8: 1708. Published online 2017 Nov 22. doi: 10.1038/s41467-017-01485-5
PMCID:
PMC5700061
AbstractArticlePDF–2.6M
19.
Inhibition of insulin/PI3K/AKT signaling decreases adipose Sortilin 1 in mice and 3T3-L1 adipocytes
Jibiao Li, Cheng Chen, Yuan Li, David J. Matye, Yifeng Wang, Wen-Xing Ding, Tiangang Li
Biochim Biophys Acta. Author manuscript; available in PMC 2018 Nov 1.
Published in final edited form as: Biochim Biophys Acta. 2017 Nov; 1863(11): 2924–2933. Published online 2017 Aug 24. doi: 10.1016/j.bbadis.2017.08.012
PMCID:
PMC5659898
AbstractArticlePDF–3.2M
20.
Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations
Xiaolai Zhou, Lirong Sun, Oliver Bracko, Ji Whae Choi, Yan Jia, Alissa L. Nana, Owen Adam Brady, Jean C. Cruz Hernandez, Nozomi Nishimura, William W. Seeley, Fenghua Hu
Nat Commun. 2017; 8: 15277. Published online 2017 May 25. doi: 10.1038/ncomms15277
PMCID:
PMC5477518
AbstractArticlePDF–8.6M

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