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Select item 86945901.

Endosomal sorting drives the formation of axonal prion protein endoggresomes

Romain Chassefeyre, Tai Chaiamarit, Adriaan Verhelle, Sammy Weiser Novak, Leonardo R. Andrade, André D. G. Leitão, Uri Manor, Sandra E. Encalada

Sci Adv. 2021 Dec; 7(52): eabg3693. Published online 2021 Dec 22. doi: 10.1126/sciadv.abg3693

PMCID:: PMC8694590

Abstract Article PDF–13M

Select item 85213122.

The glycine arginine‐rich domain of the RNA‐binding protein nucleolin regulates its subcellular localization

Ella Doron‐Mandel, Indrek Koppel, Ofri Abraham, Ida Rishal, Terika P Smith, Courtney N Buchanan, Pabitra K Sahoo, Jan Kadlec, Juan A Oses‐Prieto, Riki Kawaguchi, Stefanie Alber, Eitan Erez Zahavi, Pierluigi Di Matteo, Agostina Di Pizio, Didi‐Andreas Song, Nataliya Okladnikov, Dalia Gordon, Shifra Ben‐Dor, Rebecca Haffner‐Krausz, Giovanni Coppola, Alma L Burlingame, Pavel Jungwirth, Jeffery L Twiss, Mike Fainzilber

EMBO J. 2021 Oct 18; 40(20): e107158. Published online 2021 Sep 13. doi: 10.15252/embj.2020107158

PMCID:: PMC8521312

Abstract Article PDF–5.0M

Select item 79453323.

Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport

Xu-Qiao Chen, Utpal Das, Gooho Park, William C. Mobley

Alzheimers Res Ther. 2021; 13: 59. Published online 2021 Mar 10. doi: 10.1186/s13195-021-00796-6

PMCID:: PMC7945332

Abstract Article PDF–2.9M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74159915.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 73702306.

Drp1 overexpression induces desmin disassembling and drives kinesin-1 activation promoting mitochondrial trafficking in skeletal muscle

Matteo Giovarelli, Silvia Zecchini, Emanuele Martini, Massimiliano Garrè, Sara Barozzi, Michela Ripolone, Laura Napoli, Marco Coazzoli, Chiara Vantaggiato, Paulina Roux-Biejat, Davide Cervia, Claudia Moscheni, Cristiana Perrotta, Dario Parazzoli, Emilio Clementi, Clara De Palma

Cell Death Differ. 2020 Aug; 27(8): 2383–2401. Published online 2020 Feb 10. doi: 10.1038/s41418-020-0510-7

PMCID:: PMC7370230

Abstract Article PDF–7.5M

Select item 71884417.

Kinesin-1-mediated axonal transport of CB1 receptors is required for cannabinoid-dependent axonal growth and guidance

Trinidad M. M. Saez, Iván Fernandez Bessone, María S. Rodriguez, Matías Alloatti, María G. Otero, Lucas E. Cromberg, Victorio M. Pozo Devoto, Gonzalo Oubiña, Lucas Sosa, Mariano G. Buffone, Diego M. Gelman, Tomás L. Falzone

Development. 2020 Apr 15; 147(8): dev184069. Published online 2020 Apr 20. doi: 10.1242/dev.184069

PMCID:: PMC7188441

Abstract Article

Select item 70416768.

Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain

Min Lee, Yen-Chen Liu, Chen Chen, Chi-Huan Lu, Shao-Tzu Lu, Tzyy-Nan Huang, Meng-Tsung Hsu, Yi-Ping Hsueh, Pei-Lin Cheng

J Cell Biol. 2020 Feb 3; 219(2): e201903033. Published online 2020 Jan 7. doi: 10.1083/jcb.201903033

PMCID:: PMC7041676

Abstract Article PDF–5.4M

Select item 69939259.

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers

Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang

FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R

PMCID:: PMC6993925

Abstract Article

Select item 674078010.

Alzheimer's Presenilin 1 Mutations Impair Kinesin-Based Axonal Transport

Gustavo Pigino, Gerardo Morfini, Alejandra Pelsman, Mark P. Mattson, Scott T. Brady, Jorge Busciglio

J Neurosci. 2003 Jun 1; 23(11): 4499–4508. doi: 10.1523/JNEUROSCI.23-11-04499.2003

PMCID:: PMC6740780

Abstract Article PDF–383K

Select item 645167011.

DOC2B promotes insulin sensitivity in mice via a novel KLC1-dependent mechanism in skeletal muscle

Jing Zhang, Eunjin Oh, Karla E. Merz, Arianne Aslamy, Rajakrishnan Veluthakal, Vishal A. Salunkhe, Miwon Ahn, Ragadeepthi Tunduguru, Debbie C. Thurmond

Diabetologia. Author manuscript; available in PMC 2020 May 1.

Published in final edited form as: Diabetologia. 2019 May; 62(5): 845–859. Published online 2019 Feb 1. doi: 10.1007/s00125-019-4824-2

PMCID:: PMC6451670

Abstract Article PDF–1.4M

Select item 621465512.

Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors

Stefano Pernigo, Magda S Chegkazi, Yan Y Yip, Conor Treacy, Giulia Glorani, Kjetil Hansen, Argyris Politis, Soi Bui, Mark P Dodding, Roberto A Steiner

eLife. 2018; 7: e38362. Published online 2018 Oct 15. doi: 10.7554/eLife.38362

PMCID:: PMC6214655

Abstract Article PDF–5.1M

Select item 573930013.

Phosphorylation of KLC1 modifies interaction with JIP1 and abolishes the enhanced fast velocity of APP transport by kinesin-1

Kyoko Chiba, Ko-yi Chien, Yuriko Sobu, Saori Hata, Shun Kato, Tadashi Nakaya, Yasushi Okada, Angus C. Nairn, Masataka Kinjo, Hidenori Taru, Rong Wang, Toshiharu Suzuki

Mol Biol Cell. 2017 Dec 15; 28(26): 3857–3869. doi: 10.1091/mbc.E17-05-0303

PMCID:: PMC5739300

Abstract Article PDF–3.2M

Select item 564508214.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594