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Items: 1 to 20 of 21

1.
Proteinase 3 depletion attenuates leukemia by promoting myeloid differentiation
Huan Liu, Lu Sun, Hongfei Zhao, Zihan Zhao, Shiyue Zhang, Shan Jiang, Tianran Cheng, Xiaohan Wang, Tong Wang, Ya Shao, Haiyan Zhu, Huijuan Han, Yigeng Cao, Erlie Jiang, Yihai Cao, Yuanfu Xu
Cell Death Differ. 2024 Jun; 31(6): 697–710. Published online 2024 Apr 8. doi: 10.1038/s41418-024-01288-4
PMCID:
PMC11165011
AbstractArticlePDF–5.2M
2.
Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks
Milas Ugur, R. Jacob Labios, Chloe Fenton, Konrad Knöpper, Katarzyna Jobin, Fabian Imdahl, Gosia Golda, Kathrin Hoh, Anika Grafen, Tsuneyasu Kaisho, Antoine-Emmanuel Saliba, Dominic Grün, Georg Gasteiger, Marc Bajénoff, Wolfgang Kastenmüller
Immunity. 2023 Aug 8; 56(8): 1778–1793.e10. doi: 10.1016/j.immuni.2023.06.020
PMCID:
PMC10433941
AbstractArticle
3.
Mice Deficient in the IL-1β Activation Genes Prtn3, Elane, and Casp1 Are Protected Against the Development of Obesity-Induced NAFLD
Andreea-Manuela Mirea, Rinke Stienstra, Thirumala-Devi Kanneganti, Cees J. Tack, Triantafyllos Chavakis, Erik J.M. Toonen, Leo A.B. Joosten
Inflammation. 2020; 43(3): 1054–1064. Published online 2020 Jan 30. doi: 10.1007/s10753-020-01190-4
PMCID:
PMC7280336
AbstractArticlePDF–2.9M
4.
Proteinase 3 Limits the Number of Hematopoietic Stem and Progenitor Cells in Murine Bone Marrow
Kutay Karatepe, Haiyan Zhu, Xiaoyu Zhang, Rongxia Guo, Hiroto Kambara, Fabien Loison, Peng Liu, Hongbo Yu, Qian Ren, Xiao Luo, John Manis, Tao Cheng, Fengxia Ma, Yuanfu Xu, Hongbo R. Luo
Stem Cell Reports. 2018 Nov 13; 11(5): 1092–1105. Published online 2018 Nov 1. doi: 10.1016/j.stemcr.2018.10.004
PMCID:
PMC6235012
AbstractArticlePDF–3.3M
5.
Activation of Proteinase 3 Contributes to Nonalcoholic Fatty Liver Disease and Insulin Resistance
Erik JM Toonen, Andreea-Manuela Mirea, Cees J Tack, Rinke Stienstra, Dov B Ballak, Janna A van Diepen, Anneke Hijmans, Triantafyllos Chavakis, Wim H Dokter, Christine TN Pham, Mihai G Netea, Charles A Dinarello, Leo AB Joosten
Mol Med. 2016; 22: 202–214. Published online 2016 May 24. doi: 10.2119/molmed.2016.00033
PMCID:
PMC5004724
AbstractArticlePDF–8.9M
6.
Neutrophil extracellular traps license macrophages and Th17 cells for cytokine production in atherosclerosis
Annika Warnatsch, Marianna Ioannou, Qian Wang, Venizelos Papayannopoulos
Science. Author manuscript; available in PMC 2016 May 3.
Published in final edited form as: Science. 2015 Jul 17; 349(6245): 316–320. Published online 2015 Jul 16. doi: 10.1126/science.aaa8064
PMCID:
PMC4854322
AbstractArticlePDF–4.9M
7.
Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis
Arnaud Millet, Katherine R. Martin, Francis Bonnefoy, Philippe Saas, Julie Mocek, Manal Alkan, Benjamin Terrier, Anja Kerstein, Nicola Tamassia, Senthil Kumaran Satyanarayanan, Amiram Ariel, Jean-Antoine Ribeil, Loïc Guillevin, Marco A. Cassatella, Antje Mueller, Nathalie Thieblemont, Peter Lamprecht, Luc Mouthon, Sylvain Perruche, Véronique Witko-Sarsat
J Clin Invest. 2015 Nov 2; 125(11): 4107–4121. Published online 2015 Oct 5. doi: 10.1172/JCI78182
PMCID:
PMC4639994
AbstractArticlePDF–4.3M
8.
Interferon Regulatory Factor 8 (IRF8) Interacts with the B Cell Lymphoma 6 (BCL6) Corepressor BCOR
Jeongheon Yoon, Xianxum Feng, Yong-Soo Kim, Dong-Mi Shin, Katerina Hatzi, Hongsheng Wang, Herbert C. Morse, III
J Biol Chem. 2014 Dec 5; 289(49): 34250–34257. Published online 2014 Oct 20. doi: 10.1074/jbc.M114.571182
PMCID:
PMC4256356
AbstractArticlePDF–1.2M
9.
PR3-ANCA: A Promising Biomarker in Primary Sclerosing Cholangitis (PSC)
Laura M. Stinton, Chelsea Bentow, Michael Mahler, Gary L. Norman, Bertus Eksteen, Andrew L. Mason, Gilaad G. Kaplan, Bjorn Lindkvist, Gideon M. Hirschfield, Piotr Milkiewicz, Angela Cheung, Harry L. A. Janssen, Marvin J. Fritzler
PLoS One. 2014; 9(11): e112877. Published online 2014 Nov 14. doi: 10.1371/journal.pone.0112877
PMCID:
PMC4232573
AbstractArticlePDF–363K
10.
Proteinase 3–dependent caspase-3 cleavage modulates neutrophil death and inflammation
Fabien Loison, Haiyan Zhu, Kutay Karatepe, Anongnard Kasorn, Peng Liu, Keqiang Ye, Jiaxi Zhou, Shannan Cao, Haiyan Gong, Dieter E. Jenne, Eileen Remold-O’Donnell, Yuanfu Xu, Hongbo R. Luo
J Clin Invest. 2014 Oct 1; 124(10): 4445–4458. Published online 2014 Sep 2. doi: 10.1172/JCI76246
PMCID:
PMC4191030
AbstractArticlePDF–3.9M
11.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
12.
Contradictory Functions (Activation/Termination) of Neutrophil Proteinase 3 Enzyme (PR3) in Interleukin-33 Biological Activity
Suyoung Bae, Taebong Kang, Jaewoo Hong, Siyoung Lee, Jida Choi, Hyunjhung Jhun, Areum Kwak, Kwangwon Hong, Eunsom Kim, Seunghyun Jo, Soohyun Kim
J Biol Chem. 2012 Mar 9; 287(11): 8205–8213. Published online 2012 Jan 23. doi: 10.1074/jbc.M111.295055
PMCID:
PMC3318695
AbstractArticlePDF–2.3M
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
TNF-α–dependent loss of IKKβ-deficient myeloid progenitors triggers a cytokine loop culminating in granulocytosis
Arun K. Mankan, Ozge Canli, Sarah Schwitalla, Paul Ziegler, Jurg Tschopp, Thomas Korn, Florian R. Greten
Proc Natl Acad Sci U S A. 2011 Apr 19; 108(16): 6567–6572. Published online 2011 Apr 4. doi: 10.1073/pnas.1018331108
PMCID:
PMC3080999
AbstractArticlePDF–978K
15.
Anti-PR3 immune responses induce segmental and necrotizing glomerulonephritis
V C Primo, S Marusic, C C Franklin, W H Goldmann, C G Achaval, R N Smith, M A Arnaout, B Nikolic
Clin Exp Immunol. 2010 Mar; 159(3): 327–337. doi: 10.1111/j.1365-2249.2009.04072.x
PMCID:
PMC2819498
AbstractArticlePDF–573K
16.
Structural Characterization of Mouse Neutrophil Serine Proteases and Identification of Their Substrate Specificities: RELEVANCE TO MOUSE MODELS OF HUMAN INFLAMMATORY DISEASES
Timofey Kalupov, Michèle Brillard-Bourdet, Sébastien Dadé, Hélène Serrano, Julien Wartelle, Nicolas Guyot, Luiz Juliano, Thierry Moreau, Azzaq Belaaouaj, Francis Gauthier
J Biol Chem. 2009 Dec 4; 284(49): 34084–34091. Published online 2009 Oct 15. doi: 10.1074/jbc.M109.042903
PMCID:
PMC2797179
AbstractArticlePDF–2.1M
17.
Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin
Kai Kessenbrock, Leopold Fröhlich, Michael Sixt, Tim Lämmermann, Heiko Pfister, Andrew Bateman, Azzaq Belaaouaj, Johannes Ring, Markus Ollert, Reinhard Fässler, Dieter E. Jenne
J Clin Invest. 2008 Jul 1; 118(7): 2438–2447. Published online 2008 Jun 20. doi: 10.1172/JCI34694
PMCID:
PMC2430496
AbstractArticlePDF–1.0M
18.
Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier
Lisa M. Sevilla, Rachida Nachat, Karen R. Groot, John F. Klement, Jouni Uitto, Philippe Djian, Arto Määttä, Fiona M. Watt
J Cell Biol. 2007 Dec 31; 179(7): 1599–1612. doi: 10.1083/jcb.200706187
PMCID:
PMC2373502
AbstractArticlePDF–5.1M
19.
Secretory Granule Proteases in Rat Mast Cells. Cloning of 10 Different Serine Proteases and a Carboxypeptidase A from Various Rat Mast Cell Populations
Claudia Lützelschwab, Gunnar Pejler, Maria Aveskogh, Lars Hellman
J Exp Med. 1997 Jan 6; 185(1): 13–30. doi: 10.1084/jem.185.1.13
PMCID:
PMC2196094
AbstractArticlePDF–731K
20.
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands
Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100
Correction in:
Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.
PMCID:
PMC283554
AbstractArticlePDF–481K

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