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Items: 1 to 20 of 29

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
3.
The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery
Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane
Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054
PMCID:
PMC9015699
AbstractArticlePDF–3.3M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
Schwann-Cell-Specific Deletion of Phosphatidylinositol 4-Kinase Alpha Causes Aberrant Myelination
Alejandro Alvarez-Prats, Ivana Bjelobaba, Zane Aldworth, Takashi Baba, Daniel Abebe, Yeun Ju Kim, Stanko S. Stojilkovic, Mark Stopfer, Tamas Balla
Cell Rep. Author manuscript; available in PMC 2020 Jun 3.
Published in final edited form as: Cell Rep. 2018 Jun 5; 23(10): 2881–2890. doi: 10.1016/j.celrep.2018.05.019
PMCID:
PMC7268203
AbstractArticlePDF–1.8M
6.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
AbstractArticlePDF–7.7M
7.
A Forward Genetic Screen Targeting the Endothelium Reveals a Regulatory Role for the Lipid Kinase Pi4ka in Myelo- and Erythropoiesis
Safiyyah Ziyad, Jesse D. Riordan, Ann M. Cavanaugh, Trent Su, Gloria E. Hernandez, Georg Hilfenhaus, Marco Morselli, Kristine Huynh, Kevin Wang, Jau-Nian Chen, Adam J. Dupuy, M. Luisa Iruela-Arispe
Cell Rep. Author manuscript; available in PMC 2018 Feb 27.
Published in final edited form as: Cell Rep. 2018 Jan 30; 22(5): 1211–1224. doi: 10.1016/j.celrep.2018.01.017
PMCID:
PMC5828030
AbstractArticlePDF–1.3M
8.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
9.
Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling
Brent Wilkinson, Jing Li, Marcelo P. Coba
Sci Rep. 2017; 7: 5272. Published online 2017 Jul 13. doi: 10.1038/s41598-017-05588-3
PMCID:
PMC5509740
AbstractArticlePDF–4.6M
10.
Widespread and dynamic translational control of red blood cell development
Juan R. Alvarez-Dominguez, Xu Zhang, Wenqian Hu
Blood. 2017 Feb 2; 129(5): 619–629. Prepublished online 2016 Nov 29. doi: 10.1182/blood-2016-09-741835
PMCID:
PMC5290990
AbstractArticle
11.
Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles
Anja E. Eisenhardt, Adrian Sprenger, Michael Röring, Ricarda Herr, Florian Weinberg, Martin Köhler, Sandra Braun, Joachim Orth, Britta Diedrich, Ulrike Lanner, Natalja Tscherwinski, Simon Schuster, Nicolas Dumaz, Enrico Schmidt, Ralf Baumeister, Andreas Schlosser, Jörn Dengjel, Tilman Brummer
Oncotarget. 2016 May 3; 7(18): 26628–26652. Published online 2016 Mar 28. doi: 10.18632/oncotarget.8427
PMCID:
PMC5042004
AbstractArticlePDF–7.5M
12.
Mouse and Human CRKL Is Dosage Sensitive for Cardiac Outflow Tract Formation
Silvia E. Racedo, Donna M. McDonald-McGinn, Jonathan H. Chung, Elizabeth Goldmuntz, Elaine Zackai, Beverly S. Emanuel, Bin Zhou, Birgit Funke, Bernice E. Morrow
Am J Hum Genet. 2015 Feb 5; 96(2): 235–244. doi: 10.1016/j.ajhg.2014.12.025
PMCID:
PMC4320261
AbstractArticlePDF–1.3M
13.
The Machinery at Endoplasmic Reticulum-Plasma Membrane Contact Sites Contributes to Spatial Regulation of Multiple Legionella Effector Proteins
Andree Hubber, Kohei Arasaki, Fubito Nakatsu, Camille Hardiman, David Lambright, Pietro De Camilli, Hiroki Nagai, Craig R. Roy
PLoS Pathog. 2014 Jul; 10(7): e1004222. Published online 2014 Jul 3. doi: 10.1371/journal.ppat.1004222
PMCID:
PMC4081824
AbstractArticlePDF–4.9M
14.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
15.
Pharmacological and Genetic Targeting of the PI4KA Enzyme Reveals Its Important Role in Maintaining Plasma Membrane Phosphatidylinositol 4-Phosphate and Phosphatidylinositol 4,5-Bisphosphate Levels
Naveen Bojjireddy, Janos Botyanszki, Gerald Hammond, Donald Creech, Richard Peterson, Daniel C. Kemp, Mark Snead, Randy Brown, Alastair Morrison, Steve Wilson, Steve Harrison, Chris Moore, Tamas Balla
J Biol Chem. 2014 Feb 28; 289(9): 6120–6132. Published online 2014 Jan 10. doi: 10.1074/jbc.M113.531426
PMCID:
PMC3937678
AbstractArticlePDF–2.3M
16.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
17.
PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity
Fubito Nakatsu, Jeremy M. Baskin, Jeeyun Chung, Lukas B. Tanner, Guanghou Shui, Sang Yoon Lee, Michelle Pirruccello, Mingming Hao, Nicholas T. Ingolia, Markus R. Wenk, Pietro De Camilli
J Cell Biol. 2012 Dec 10; 199(6): 1003–1016. doi: 10.1083/jcb.201206095
PMCID:
PMC3518224
AbstractArticlePDF–3.4M
18.
Evaluation of Phosphatidylinositol-4-Kinase IIIα as a Hepatitis C Virus Drug Target
Frédéric H. Vaillancourt, Martine Brault, Louise Pilote, Nathalie Uyttersprot, Elias T. Gaillard, James H. Stoltz, Brian L. Knight, Lynn Pantages, Mary McFarland, Steffen Breitfelder, Tim T. Chiu, Louiza Mahrouche, Anne-Marie Faucher, Mireille Cartier, Michael G. Cordingley, Richard C. Bethell, Huiping Jiang, Peter W. White, George Kukolj
J Virol. 2012 Nov; 86(21): 11595–11607. doi: 10.1128/JVI.01320-12
PMCID:
PMC3486294
AbstractArticlePDF–3.1M
19.
Mapping the Nephronophthisis-Joubert-Meckel-Gruber Protein Network Reveals Ciliopathy Disease Genes and Pathways
Liyun Sang, Julie J. Miller, Kevin C. Corbit, Rachel H. Giles, Matthew J. Brauer, Edgar A. Otto, Lisa M. Baye, Xiaohui Wen, Suzie J. Scales, Mandy Kwong, Erik G. Huntzicker, Mindan K. Sfakianos, Wendy Sandoval, J. Fernando Bazan, Priya Kulkarni, Francesc R. Garcia-Gonzalo, Allen D. Seol, John F. O'Toole, Susanne Held, Heiko M. Reutter, William S. Lane, Muhammad Arshad Rafiq, Abdul Noor, Muhammad Ansar, Akella Radha Rama Devi, Val C. Sheffield, Diane C. Slusarski, John B. Vincent, Daniel A. Doherty, Friedhelm Hildebrandt, Jeremy F. Reiter, Peter K. Jackson
Cell. Author manuscript; available in PMC 2012 Jun 26.
Published in final edited form as: Cell. 2011 May 13; 145(4): 513–528. doi: 10.1016/j.cell.2011.04.019
PMCID:
PMC3383065
AbstractArticlePDF–2.0M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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