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Items: 1 to 20 of 37

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Cyb5r3 activation rescues secondary failure to sulfonylurea but not β-cell dedifferentiation
Hitoshi Watanabe, Shun-ichiro Asahara, Jinsook Son, Wendy M. McKimpson, Rafael de Cabo, Domenico Accili
PLoS One. 2024; 19(2): e0297555. Published online 2024 Feb 9. doi: 10.1371/journal.pone.0297555
PMCID:
PMC10857566
AbstractArticlePDF–1.8M
3.
CYB5R3 functions as a tumor suppressor by inducing ER stress-mediated apoptosis in lung cancer cells via the PERK-ATF4 and IRE1α-JNK pathways
Joo-Young Im, Soo Jin Kim, Jong-Lyul Park, Tae-Hee Han, Woo-il Kim, Inhyub Kim, Bomin Ko, So-Young Chun, Mi-Jung Kang, Bo-Kyung Kim, Sol A. Jeon, Seon-Kyu Kim, Incheol Ryu, Seon-Young Kim, Ki-Hoan Nam, Inah Hwang, Hyun Seung Ban, Misun Won
Exp Mol Med. 2024 Feb; 56(1): 235–249. Published online 2024 Jan 22. doi: 10.1038/s12276-024-01155-9
PMCID:
PMC10834511
AbstractArticlePDF–5.2M
4.
Bedding as a variable affecting fasting blood glucose and vascular physiology in mice
Timothy M. Sveeggen, Brant E. Isakson, Adam C. Straub, Pooneh Bagher
Am J Physiol Heart Circ Physiol. 2023 Aug 1; 325(2): H338–H345. Published online 2023 Jun 30. doi: 10.1152/ajpheart.00168.2023
PMCID:
PMC10435074
AbstractArticle
5.
CYB5R3 in type II alveolar epithelial cells protects against lung fibrosis by suppressing TGF-β1 signaling
Marta Bueno, Jazmin Calyeca, Timur Khaliullin, Megan P. Miller, Diana Alvarez, Lorena Rosas, Judith Brands, Christian Baker, Amro Nasser, Stephanie Shulkowski, August Mathien, Nneoma Uzoukwu, John Sembrat, Brenton G. Mays, Kaitlin Fiedler, Scott A. Hahn, Sonia R. Salvatore, Francisco J. Schopfer, Mauricio Rojas, Peter Sandner, Adam C. Straub, Ana L. Mora
JCI Insight. 2023 Mar 8; 8(5): e161487. Published online 2023 Mar 8. doi: 10.1172/jci.insight.161487
PMCID:
PMC10077481
AbstractArticlePDF–12M
6.
The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3
Ryosuke Ishimura, Afnan H. El-Gowily, Daisuke Noshiro, Satoko Komatsu-Hirota, Yasuko Ono, Mayumi Shindo, Tomohisa Hatta, Manabu Abe, Takefumi Uemura, Hyeon-Cheol Lee-Okada, Tarek M. Mohamed, Takehiko Yokomizo, Takashi Ueno, Kenji Sakimura, Tohru Natsume, Hiroyuki Sorimachi, Toshifumi Inada, Satoshi Waguri, Nobuo N. Noda, Masaaki Komatsu
Nat Commun. 2022; 13: 7857. Published online 2022 Dec 21. doi: 10.1038/s41467-022-35501-0
PMCID:
PMC9772183
AbstractArticlePDF–4.1M
7.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
8.
Loss of cardiomyocyte CYB5R3 impairs redox equilibrium and causes sudden cardiac death
Nolan T. Carew, Heidi M. Schmidt, Shuai Yuan, Joseph C. Galley, Robert Hall, Helene M. Altmann, Scott A. Hahn, Megan P. Miller, Katherine C. Wood, Bethann Gabris, Margaret C. Stapleton, Sean Hartwick, Marco Fazzari, Yijen L. Wu, Mohamed Trebak, Brett A. Kaufman, Charles F. McTiernan, Francisco J. Schopfer, Placido Navas, Patrick H. Thibodeau, Dennis M. McNamara, Guy Salama, Adam C. Straub
J Clin Invest. 2022 Sep 15; 132(18): e147120. Published online 2022 Sep 15. doi: 10.1172/JCI147120
PMCID:
PMC9479700
AbstractArticlePDF–15M
9.
Smooth muscle cell CYB5R3 preserves cardiac and vascular function under chronic hypoxic stress
Brittany G. Durgin, Katherine C. Wood, Scott A. Hahn, Brenda McMahon, Jeffrey J. Baust, Adam C. Straub
J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Jan 1.
Published in final edited form as: J Mol Cell Cardiol. 2022 Jan; 162: 72–80. Published online 2021 Sep 15. doi: 10.1016/j.yjmcc.2021.09.005
PMCID:
PMC8766905
AbstractArticlePDF–1.4M
10.
Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation
Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley
Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h
PMCID:
PMC8763317
AbstractArticle
11.
Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation
Shuai Yuan, Scott A. Hahn, Megan P. Miller, Subramaniam Sanker, Michael J. Calderon, Mara Sullivan, Atinuke M. Dosunmu-Ogunbi, Marco Fazzari, Yao Li, Michael Reynolds, Katherine C. Wood, Claudette M. St Croix, Donna Stolz, Eugenia Cifuentes-Pagano, Placido Navas, Sruti Shiva, Francisco J. Schopfer, Patrick J. Pagano, Adam C. Straub
Redox Biol. 2021 Nov; 47: 102166. Published online 2021 Oct 14. doi: 10.1016/j.redox.2021.102166
PMCID:
PMC8577475
AbstractArticlePDF–7.8M
12.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
13.
GGPP depletion initiates metaflammation through disequilibrating CYB5R3-dependent eicosanoid metabolism
Lisha Wei, Yan-Yan Zheng, Jie Sun, Pei Wang, Tao Tao, Yeqiong Li, Xin Chen, Yongjuan Sang, Danyang Chong, Wei Zhao, Yuwei Zhou, Ye Wang, Zhihui Jiang, Tiantian Qiu, Chao-Jun Li, Min-Sheng Zhu, Xuena Zhang
J Biol Chem. 2020 Nov 20; 295(47): 15988–16001. Published online 2020 Sep 10. doi: 10.1074/jbc.RA120.015020
PMCID:
PMC7681012
AbstractArticlePDF–3.6M
14.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
15.
Mitochondrial adaptations in liver and skeletal muscle to pro-longevity nutritional and genetic interventions: the crosstalk between calorie restriction and CYB5R3 overexpression in transgenic mice
Sandra Rodríguez-López, Sara López-Bellón, José A. González-Reyes, M. Isabel Burón, Rafael de Cabo, José M. Villalba
GeroScience. 2020 Jun; 42(3): 977–994. Published online 2020 Apr 22. doi: 10.1007/s11357-020-00187-z
PMCID:
PMC7286989
AbstractArticlePDF–1.1M
16.
Cyb5r3 links FoxO1-dependent mitochondrial dysfunction with β-cell failure
Jason Fan, Wen Du, Ja Young Kim-Muller, Jinsook Son, Taiyi Kuo, Delfina Larrea, Christian Garcia, Takumi Kitamoto, Michael J. Kraakman, Edward Owusu-Ansah, Vincenzo Cirulli, Domenico Accili
Mol Metab. 2020 Apr; 34: 97–111. Published online 2020 Feb 4. doi: 10.1016/j.molmet.2019.12.008
PMCID:
PMC7031142
AbstractArticlePDF–4.5M
17.
Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers
Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang
FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R
PMCID:
PMC6993925
AbstractArticle
18.
Loss of smooth muscle CYB5R3 amplifies angiotensin II–induced hypertension by increasing sGC heme oxidation
Brittany G. Durgin, Scott A. Hahn, Heidi M. Schmidt, Megan P. Miller, Neha Hafeez, Ilka Mathar, Daniel Freitag, Peter Sandner, Adam C. Straub
JCI Insight. 2019 Oct 3; 4(19): e129183. Published online 2019 Oct 3. doi: 10.1172/jci.insight.129183
PMCID:
PMC6795404
AbstractArticlePDF–3.0M
19.
LINC00116 codes for a mitochondrial peptide linking respiration and lipid metabolism
Anastasia Chugunova, Elizaveta Loseva, Pavel Mazin, Aleksandra Mitina, Tsimafei Navalayeu, Dmitry Bilan, Polina Vishnyakova, Maria Marey, Anna Golovina, Marina Serebryakova, Philipp Pletnev, Maria Rubtsova, Waltraud Mair, Anna Vanyushkina, Philipp Khaitovich, Vsevolod Belousov, Mikhail Vysokikh, Petr Sergiev, Olga Dontsova
Proc Natl Acad Sci U S A. 2019 Mar 12; 116(11): 4940–4945. Published online 2019 Feb 22. doi: 10.1073/pnas.1809105116
PMCID:
PMC6421467
AbstractArticlePDF–1.5M
20.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M

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