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Select item 61886691.

Dynamic acetylation of cytosolic phosphoenolpyruvate carboxykinase toggles enzyme activity between gluconeogenic and anaplerotic reactions

Pedro Latorre-Muro, Josue Baeza, Eric A. Armstrong, Ramón Hurtado-Guerrero, Francisco Corzana, Lindsay E. Wu, David A. Sinclair, Pascual López-Buesa, José A. Carrodeguas, John M. Denu

Mol Cell. Author manuscript; available in PMC 2019 Sep 6.

Published in final edited form as: Mol Cell. 2018 Sep 6; 71(5): 718–732.e9. doi: 10.1016/j.molcel.2018.07.031

PMCID:: PMC6188669

Abstract Article PDF–3.4M

Select item 60394912.

Adolescent alcohol exposure epigenetically regulates CREB signaling in the adult amygdala

Huaibo Zhang, Evan J. Kyzar, John Peyton Bohnsack, Dadasaheb M. Kokare, Tara Teppen, Subhash C. Pandey

Sci Rep. 2018; 8: 10376. Published online 2018 Jul 10. doi: 10.1038/s41598-018-28415-9

PMCID:: PMC6039491

Abstract Article PDF–2.3M

Select item 60294513.

p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis

He Huang, Shuang Tang, Ming Ji, Zhanyun Tang, Miho Shimada, Xiaojing Liu, Shankang Qi, Jason W. Locasale, Robert G. Roeder, Yingming Zhao, Xiaoling Li

Mol Cell. Author manuscript; available in PMC 2019 May 17.

Published in final edited form as: Mol Cell. 2018 May 17; 70(4): 663–678.e6. doi: 10.1016/j.molcel.2018.04.011

Correction in:: Mol Cell. 2018 Jun 7; 70(5): 984.

PMCID:: PMC6029451

Abstract Article PDF–2.0M

Select item 53864654.

Opposite effects of HDAC5 and p300 on MRTF-A-related neuronal apoptosis during ischemia/reperfusion injury in rats

Na Li, Qiong Yuan, Xiao-Lu Cao, Ying Zhang, Zhen-Li Min, Shi-Qiang Xu, Zhi-Jun Yu, Jing Cheng, Chunxiang Zhang, Xia-Min Hu

Cell Death Dis. 2017 Feb; 8(2): e2624. Published online 2017 Feb 23. doi: 10.1038/cddis.2017.16

PMCID:: PMC5386465

Abstract Article PDF–1.9M

Select item 48504245.

Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters

Afsaneh Goudarzi, Di Zhang, He Huang, Sophie Barral, Oh Kwang Kwon, Shankang Qi, Zhanyun Tang, Thierry Buchou, Anne-Laure Vitte, Tieming He, Zhongyi Cheng, Emilie Montellier, Jonathan Gaucher, Sandrine Curtet, Alexandra Debernardi, Guillaume Charbonnier, Denis Puthier, Carlo Petosa, Daniel Panne, Sophie Rousseaux, Robert G. Roeder, Yingming Zhao, Saadi Khochbin

Mol Cell. 2016 Apr 21; 62(2): 169–180. doi: 10.1016/j.molcel.2016.03.014

PMCID:: PMC4850424

Abstract Article

Select item 48135756.

p300/β-Catenin Interactions Regulate Adult Progenitor Cell Differentiation Downstream of WNT5a/Protein Kinase C (PKC)

Megan E. Rieger, Beiyun Zhou, Nicola Solomon, Mitsuhiro Sunohara, Changgong Li, Cu Nguyen, Yixin Liu, Jie-hong Pan, Parviz Minoo, Edward D. Crandall, Steven L. Brody, Michael Kahn, Zea Borok

J Biol Chem. 2016 Mar 18; 291(12): 6569–6582. Published online 2016 Feb 1. doi: 10.1074/jbc.M115.706416

PMCID:: PMC4813575

Abstract Article PDF–2.3M

Select item 46530747.

PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection

Yong Zhang, Dailing Mao, William T Roswit, Xiaohua Jin, Anand C Patel, Dhara A Patel, Eugene Agapov, Zhepeng Wang, Rose M Tidwell, Jeffrey J Atkinson, Guangming Huang, Ronald McCarthy, Jinsheng Yu, Nadezhda E Yun, Slobodan Paessler, T Glen Lawson, Natalie S Omattage, Tom J Brett, Michael J Holtzman

Nat Immunol. 2015; 16(12): 1215–1227. Published online 2015 Dec 1. doi: 10.1038/ni.3279

PMCID:: PMC4653074

Abstract Article PDF–2.9M

Select item 45012628.

Intracellular Crotonyl-CoA Stimulates Transcription Through p300-Catalyzed Histone Crotonylation

Benjamin R. Sabari, Zhanyun Tang, He Huang, Vladimir Yong-Gonzalez, Henrik Molina, Ha Eun Kong, Lunzhi Dai, Miho Shimada, Justin R. Cross, Yingming Zhao, Robert G. Roeder, C. David Allis

Mol Cell. Author manuscript; available in PMC 2016 Apr 16.

Published in final edited form as: Mol Cell. 2015 Apr 16; 58(2): 203–215. Published online 2015 Mar 26. doi: 10.1016/j.molcel.2015.02.029

Correction in:: Mol Cell. 2018 Feb 1; 69(3): 533.

PMCID:: PMC4501262

Abstract Article PDF–1.5M

Select item 42742489.

Epigenetic Regulation of Genes that Modulate Chronic Stress-induced Visceral Pain in the Peripheral Nervous System

Shuangsong Hong, Gen Zheng, John W. Wiley

Gastroenterology. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Gastroenterology. 2015 Jan; 148(1): 148–157.e7. Published online 2014 Sep 28. doi: 10.1053/j.gastro.2014.09.032

PMCID:: PMC4274248

Abstract Article PDF–607K

Select item 415552710.

P300-dependent STAT3 acetylation is necessary for angiotensin II-induced pro-fibrotic responses in renal tubular epithelial cells

Jun Ni, Yang Shen, Zhen Wang, De-cui Shao, Jia Liu, Ya-li Kong, Lan-jun Fu, Li Zhou, Hong Xue, Yu Huang, Wei Zhang, Chen Yu, Li-min Lu

Acta Pharmacol Sin. 2014 Sep; 35(9): 1157–1166. Published online 2014 Aug 4. doi: 10.1038/aps.2014.54

PMCID:: PMC4155527

Abstract Article PDF–1.6M

Select item 414093411.

New Role for Kruppel-like Factor 14 as a Transcriptional Activator Involved in the Generation of Signaling Lipids

Thiago M. de Assuncao, Gwen Lomberk, Sheng Cao, Usman Yaqoob, Angela Mathison, Douglas A. Simonetto, Robert C. Huebert, Raul A. Urrutia, Vijay H. Shah

J Biol Chem. 2014 May 30; 289(22): 15798–15809. Published online 2014 Apr 23. doi: 10.1074/jbc.M113.544346

PMCID:: PMC4140934

Abstract Article PDF–2.3M

Select item 411776412.

CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis

Ornella Cazzalini, Sabrina Sommatis, Micol Tillhon, Ilaria Dutto, Angela Bachi, Alexander Rapp, Tiziana Nardo, A. Ivana Scovassi, Daniela Necchi, M. Cristina Cardoso, Lucia A. Stivala, Ennio Prosperi

Nucleic Acids Res. 2014 Sep 1; 42(13): 8433–8448. Published online 2014 Jun 17. doi: 10.1093/nar/gku533

PMCID:: PMC4117764

Abstract Article PDF–7.4M

Select item 410806213.

High glucose induces Smad activation via the transcriptional coregulator p300 and contributes to cardiac fibrosis and hypertrophy

Antoinette Bugyei-Twum, Andrew Advani, Suzanne L Advani, Yuan Zhang, Kerri Thai, Darren J Kelly, Kim A Connelly

Cardiovasc Diabetol. 2014; 13: 89. Published online 2014 May 5. doi: 10.1186/1475-2840-13-89

PMCID:: PMC4108062

Abstract Article PDF–2.1M

Select item 406515314.

Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis

Sara L. Lewandowski, Harish P. Janardhan, Kevin M. Smee, Marcos Bachman, Zheng Sun, Mitchell A. Lazar, Chinmay M. Trivedi

Hum Mol Genet. 2014 Jul 15; 23(14): 3801–3809. Published online 2014 Feb 23. doi: 10.1093/hmg/ddu093

PMCID:: PMC4065153

Abstract Article PDF–884K

Select item 401290815.

Krüppel-like factor 4 interacts with p300 to activate mitofusin 2 gene expression induced by all-trans retinoic acid in VSMCs

Rui Zhang, Mei Han, Bin Zheng, Ying-jie Li, Ya-nan Shu, Jin-kun Wen

Acta Pharmacol Sin. 2010 Oct; 31(10): 1293–1302. Published online 2010 Aug 16. doi: 10.1038/aps.2010.96

PMCID:: PMC4012908

Abstract Article PDF–1.0M

Select item 400130716.

Sublytic C5b-9 triggers glomerular mesangial cell apoptosis via XAF1 gene activation mediated by p300-dependent IRF-1 acetylation

W Qiu, J Zhou, G Zhu, D Zhao, F He, J Zhang, Y Lu, T Yu, L Liu, Y Wang

Cell Death Dis. 2014 Apr; 5(4): e1176. Published online 2014 Apr 17. doi: 10.1038/cddis.2014.153

PMCID:: PMC4001307

Abstract Article PDF–4.9M

Select item 391150917.

p300-Dependent Acetylation of Activating Transcription Factor 5 Enhances C/EBPβ Transactivation of C/EBPα during 3T3-L1 Differentiation

Yue Zhao, Ya-Dong Zhang, You-You Zhang, Shu-Wen Qian, Zhi-Chun Zhang, Shu-Fen Li, Liang Guo, Yuan Liu, Bo Wen, Qun-Ying Lei, Qi-Qun Tang, Xi Li

Mol Cell Biol. 2014 Feb; 34(3): 315–324. doi: 10.1128/MCB.00956-13

PMCID:: PMC3911509

Abstract Article PDF–2.3M

Select item 385794618.

Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance

Casey Cook, Yari Carlomagno, Tania F. Gendron, Judy Dunmore, Kristyn Scheffel, Caroline Stetler, Mary Davis, Dennis Dickson, Matthew Jarpe, Michael DeTure, Leonard Petrucelli

Hum Mol Genet. 2014 Jan 1; 23(1): 104–116. Published online 2013 Aug 19. doi: 10.1093/hmg/ddt402

PMCID:: PMC3857946

Abstract Article PDF–1010K

Select item 372821919.

Synchronous Recruitment of Epigenetic Modifiers to Endotoxin Synergistically Activated Tnf-α Gene in Acute Kidney Injury

Karol Bomsztyk, Steve Flanagin, Daniel Mar, Michal Mikula, Ali Johnson, Richard Zager, Oleg Denisenko

PLoS One. 2013; 8(7): e70322. Published online 2013 Jul 30. doi: 10.1371/journal.pone.0070322

PMCID:: PMC3728219

Abstract Article PDF–2.1M

Select item 372338920.

TGF-β Induces Acetylation of Chromatin and of Ets-1 to Alleviate Repression of miR-192 in Diabetic Nephropathy

Mitsuo Kato, Varun Dang, Mei Wang, Jung Tak Park, Supriya Deshpande, Swati Kadam, Armen Mardiros, Yumei Zhan, Peter Oettgen, Sumanth Putta, Hang Yuan, Linda Lanting, Rama Natarajan

Sci Signal. Author manuscript; available in PMC 2014 Jun 4.

Published in final edited form as: Sci Signal. 2013 Jun 4; 6(278): ra43. Published online 2013 Jun 4. doi: 10.1126/scisignal.2003389