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Items: 1 to 20 of 57

1.
The W101C KCNJ5 Mutation Induces Slower Pacing by Constitutively Active GIRK Channels in hiPSC-Derived Cardiomyocytes
Anne Kayser, Sven Dittmann, Tomo Šarić, Giulia Mearini, Arie O. Verkerk, Eric Schulze-Bahr
Int J Mol Sci. 2023 Oct; 24(20): 15290. Published online 2023 Oct 18. doi: 10.3390/ijms242015290
PMCID:
PMC10607318
AbstractArticlePDF–2.2M
2.
Cardiovascular and metabolic characters of KCNJ5 somatic mutations in primary aldosteronism
Yi-Yao Chang, Bo-Ching Lee, Zheng-Wei Chen, Cheng-Hsuan Tsai, Chin-Chen Chang, Che-Wei Liao, Chien-Ting Pan, Kang-Yung Peng, Chia-Hung Chou, Ching-Chu Lu, Vin-Cent Wu, Chi-Sheng Hung, Yen-Hung Lin, TAIPAI study group
Front Endocrinol (Lausanne) 2023; 14: 1061704. Published online 2023 Mar 6. doi: 10.3389/fendo.2023.1061704
PMCID:
PMC10025475
AbstractArticlePDF–4.1M
3.
Histopathology and Genetic Causes of Primary Aldosteronism in Young Adults
Kazutaka Nanba, Jessica E Baker, Amy R Blinder, Nolan R Bick, Chia-Jen Liu, Jung Soo Lim, Heather Wachtel, Debbie L Cohen, Tracy Ann Williams, Martin Reincke, Melanie L Lyden, Irina Bancos, William F Young, Tobias Else, Thomas J Giordano, Aaron M Udager, William E Rainey
J Clin Endocrinol Metab. 2022 Sep; 107(9): 2473–2482. Published online 2022 Jul 2. doi: 10.1210/clinem/dgac408
PMCID:
PMC9761569
AbstractArticle
4.
Insight into the phospholipid binding preferences of Kir3.4
Pei Qiao, Samantha Schrecke, Jixing Lyu, Yun Zhu, Tianqi Zhang, Amanda Benavides, Arthur Laganowsky
Biochemistry. Author manuscript; available in PMC 2022 Oct 15.
Published in final edited form as: Biochemistry. 2021 Dec 21; 60(50): 3813–3821. Published online 2021 Nov 30. doi: 10.1021/acs.biochem.1c00615
PMCID:
PMC9569133
AbstractArticlePDF–1.1M
5.
Clinical Translationality of KCNJ5 Mutation in Aldosterone Producing Adenoma
Takumi Kitamoto, Tetsuo Nishikawa
Int J Mol Sci. 2022 Aug; 23(16): 9042. Published online 2022 Aug 12. doi: 10.3390/ijms23169042
PMCID:
PMC9409469
AbstractArticlePDF–1.0M
6.
KCNJ5 Somatic Mutation Is Associated With Higher Aortic Wall Thickness and Less Calcification in Patients With Aldosterone-Producing Adenoma
Bo-Ching Lee, Victor Jing-Wei Kang, Chien-Ting Pan, Jia-Zheng Huang, Yu-Li Lin, Yi-Yao Chang, Cheng-Hsuan Tsai, Chia-Hung Chou, Zheng-Wei Chen, Che-Wei Liao, Yu-Wei Chiu, Vin-Cent Wu, Chi-Sheng Hung, Chin-Chen Chang, Yen-Hung Lin
Front Endocrinol (Lausanne) 2022; 13: 830130. Published online 2022 Mar 2. doi: 10.3389/fendo.2022.830130
PMCID:
PMC8924484
AbstractArticlePDF–355K
7.
Human adrenal glomerulosa cells express K2P and GIRK potassium channels that are inhibited by ANG II and ACTH
John J. Enyeart, Judith A. Enyeart
Am J Physiol Cell Physiol. 2021 Jul 1; 321(1): C158–C175. Published online 2021 May 26. doi: 10.1152/ajpcell.00118.2021
PMCID:
PMC8321792
AbstractArticle
8.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
Nucleotide inhibition of the pancreatic ATP-sensitive K+ channel explored with patch-clamp fluorometry
Samuel G Usher, Frances M Ashcroft, Michael C Puljung
eLife. 2020; 9: e52775. Published online 2020 Jan 7. doi: 10.7554/eLife.52775
PMCID:
PMC7004565
AbstractArticlePDF–3.9M
11.
Tumor Cell Subtypes Based on the Intracellular Hormonal Activity in KCNJ5-Mutated Aldosterone-Producing Adenoma
Yuto Yamazaki, Kei Omata, Yuta Tezuka, Yoshikiyo Ono, Ryo Morimoto, Yuzu Adachi, Kazue Ise, Yasuhiro Nakamura, Celso E. Gomez-Sanchez, Yukiko Shibahara, Takumi Kitamoto, Tetsuo Nishikawa, Sadayoshi Ito, Fumitoshi Satoh, Hironobu Sasano
Hypertension. Author manuscript; available in PMC 2019 Sep 25.
Published in final edited form as: Hypertension. 2018 Sep; 72(3): 632–640. doi: 10.1161/HYPERTENSIONAHA.118.10907
PMCID:
PMC6759988
AbstractArticlePDF–1.4M
12.
18-Oxocortisol Synthesis in Aldosterone-Producing Adrenocortical Adenoma and Significance of KCNJ5 Mutation Status
Yuta Tezuka, Yuto Yamazaki, Masaaki Kitada, Ryo Morimoto, Masataka Kudo, Kazumasa Seiji, Kei Takase, Yoshihide Kawasaki, Koji Mitsuzuka, Akihiro Ito, Jun Nishikawa, Noriko Asai, Yasuhiro Nakamura, Celso E. Gomez-Sanchez, Sadayoshi Ito, Mari Dezawa, Hironobu Sasano, Fumitoshi Satoh
Hypertension. Author manuscript; available in PMC 2020 Jun 1.
Published in final edited form as: Hypertension. 2019 Jun; 73(6): 1283–1290. doi: 10.1161/HYPERTENSIONAHA.118.12064
PMCID:
PMC6758910
AbstractArticlePDF–488K
13.
PRIMARY ALDOSTERONISM: KCNJ5 MUTATIONS AND ADRENOCORTICAL CELL GROWTH
Yuhong Yang, Celso E. Gomez-Sanchez, Diana Jaquin, Elke Tatjana Aristizabal Prada, Lucie S. Meyer, Thomas Knösel, Holger Schneider, Felix Beuschlein, Martin Reincke, Tracy Ann Williams
Hypertension. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: Hypertension. 2019 Oct; 74(4): 809–816. Published online 2019 Aug 26. doi: 10.1161/HYPERTENSIONAHA.119.13476
PMCID:
PMC6739168
AbstractArticlePDF–1.4M
14.
A G-protein-activated inwardly rectifying K+ channel (GIRK4) from human hippocampus associates with other GIRK channels
A Spauschus, KU Lentes, E Wischmeyer, E Dissmann, C Karschin, A Karschin
J Neurosci. 1996 Feb 1; 16(3): 930–938. doi: 10.1523/JNEUROSCI.16-03-00930.1996
PMCID:
PMC6578796
AbstractPDF–2.4M
15.
CELLULAR AND GENETIC CAUSES OF IDIOPATHIC HYPERALDOSTERONISM
Kei Omata, Fumitoshi Satoh, Ryo Morimoto, Sadayoshi Ito, Yuto Yamazaki, Yasuhiro Nakamura, Sharath K. Anand, Zeng Guo, Michael Stowasser, Hironobu Sasano, Scott A. Tomlins, William E. Rainey
Hypertension. Author manuscript; available in PMC 2019 Oct 1.
Published in final edited form as: Hypertension. 2018 Oct; 72(4): 874–880. doi: 10.1161/HYPERTENSIONAHA.118.11086
PMCID:
PMC6207209
AbstractArticlePDF–573K
16.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
17.
Macrolides selectively inhibit mutant KCNJ5 potassium channels that cause aldosterone-producing adenoma
Ute I. Scholl, Laura Abriola, Chengbiao Zhang, Esther N. Reimer, Mark Plummer, Barbara I. Kazmierczak, Junhui Zhang, Denton Hoyer, Jane S. Merkel, Wenhui Wang, Richard P. Lifton
J Clin Invest. 2017 Jun 30; 127(7): 2739–2750. Published online 2017 Jun 12. doi: 10.1172/JCI91733
PMCID:
PMC5490757
AbstractArticlePDF–1.3M
18.
Somatic KCNJ5 mutation occurring early in adrenal development may cause a novel form of juvenile primary aldosteronism
Ai Tamura, Koshiro Nishimoto, Tsugio Seki, Yoko Matsuzawa, Jun Saito, Masao Omura, Celso E. Gomez-Sanchez, Kohzoh Makita, Seishi Matsui, Nobukazu Moriya, Atsushi Inoue, Maki Nagata, Hironobu Sasano, Yasuhiro Nakamura, Yuto Yamazaki, Yasuaki Kabe, Kuniaki Mukai, Takeo Kosaka, Mototsugu Oya, Sachiko Suematsu, Tetsuo Nishikawa
Mol Cell Endocrinol. Author manuscript; available in PMC 2018 Feb 5.
Published in final edited form as: Mol Cell Endocrinol. 2017 Feb 5; 441: 134–139. Published online 2016 Aug 8. doi: 10.1016/j.mce.2016.07.031
PMCID:
PMC5482904
AbstractArticlePDF–1.0M
19.
Arterial stiffness and blood pressure improvement in aldosterone-producing adenoma harboring KCNJ5 mutations after adrenalectomy
Chia-Hui Chang, Ya-Hui Hu, Yao-Chou Tsai, Che-Hsiung Wu, Shuo-Meng Wang, Lian-Yu Lin, Yen-Hung Lin, Fumitoshi Satoh, Kwan-Dun Wu, Vin-Cent Wu
Oncotarget. 2017 May 2; 8(18): 29984–29995. Published online 2017 Mar 16. doi: 10.18632/oncotarget.16269
PMCID:
PMC5444719
AbstractArticlePDF–4.7M
20.
Novel Insertion Mutation in KCNJ5 Channel Produces Constitutive Aldosterone Release From H295R Cells
Iris Hardege, Shengxin Xu, Richard D. Gordon, Andrew J. Thompson, Nichola Figg, Michael Stowasser, Ruth Murrell-Lagnado, Kevin M. O'Shaughnessy
Mol Endocrinol. 2015 Oct; 29(10): 1522–1530. Published online 2015 Sep 4. doi: 10.1210/me.2015-1195
PMCID:
PMC5414677
AbstractArticle

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