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Items: 1 to 20 of 52

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Interplay between PML NBs and HIRA for H3.3 dynamics following type I interferon stimulus
Constance Kleijwegt, Florent Bressac, Coline Seurre, Wilhelm Bouchereau, Camille Cohen, Pascale Texier, Thomas Simonet, Laurent Schaeffer, Patrick Lomonte, Armelle Corpet
eLife. 2023; 12: e80156. Published online 2023 May 25. doi: 10.7554/eLife.80156
PMCID:
PMC10212570
AbstractArticlePDF–7.7M
3.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
4.
The H3.3 chaperone Hira complex orchestrates oocyte developmental competence
Rowena Smith, Andrej Susor, Hao Ming, Janet Tait, Marco Conti, Zongliang Jiang, Chih-Jen Lin
Development. 2022 Mar 1; 149(5): dev200044. Published online 2022 Feb 28. doi: 10.1242/dev.200044
PMCID:
PMC8959146
AbstractArticle
5.
HIRA complex presets transcriptional potential through coordinating depositions of the histone variants H3.3 and H2A.Z on the poised genes in mESCs
Yang Yang, Liwei Zhang, Chaoyang Xiong, Jun Chen, Li Wang, Zengqi Wen, Juan Yu, Ping Chen, Yanhui Xu, Jingji Jin, Yong Cai, Guohong Li
Nucleic Acids Res. 2022 Jan 11; 50(1): 191–206. Published online 2021 Dec 10. doi: 10.1093/nar/gkab1221
PMCID:
PMC8754660
AbstractArticlePDF–6.2M
6.
The histone H3.3 chaperone HIRA restrains erythroid-biased differentiation of adult hematopoietic stem cells
Rebecca L. Murdaugh, Kevin A. Hoegenauer, Ayumi Kitano, Matthew V. Holt, Matthew C. Hill, Xiangguo Shi, Jonathan F. Tiessen, Richard Chapple, Tianyuan Hu, Yu-Jung Tseng, Angelique Lin, James F. Martin, Nicolas L. Young, Daisuke Nakada
Stem Cell Reports. 2021 Aug 10; 16(8): 2014–2028. Published online 2021 Jul 8. doi: 10.1016/j.stemcr.2021.06.009
PMCID:
PMC8365107
AbstractArticlePDF–2.3M
7.
ATRX promotes heterochromatin formation to protect cells from G-quadruplex DNA-mediated stress
Yu-Ching Teng, Aishwarya Sundaresan, Ryan O’Hara, Vincent U. Gant, Minhua Li, Sara Martire, Jane N. Warshaw, Amrita Basu, Laura A. Banaszynski
Nat Commun. 2021; 12: 3887. Published online 2021 Jun 23. doi: 10.1038/s41467-021-24206-5
PMCID:
PMC8222256
AbstractArticlePDF–2.5M
8.
Defective folate metabolism causes germline epigenetic instability and distinguishes Hira as a phenotype inheritance biomarker
Georgina E. T. Blake, Xiaohui Zhao, Hong wa Yung, Graham J. Burton, Anne C. Ferguson-Smith, Russell S. Hamilton, Erica D. Watson
Nat Commun. 2021; 12: 3714. Published online 2021 Jun 17. doi: 10.1038/s41467-021-24036-5
PMCID:
PMC8211854
AbstractArticlePDF–1.9M
9.
HIRA contributes to zygote formation in mice and is implicated in human 1PN zygote phenotype
Rowena Smith, Sue J Pickering, Anna Kopakaki, K J Thong, Richard A Anderson, Chih-Jen Lin
Reproduction. 2021 Jun 1; 161(6): 697–707. Published online 2021 Apr 8. doi: 10.1530/REP-20-0636
PMCID:
PMC8188263
AbstractArticlePDF–3.0M
10.
HIRA stabilizes skeletal muscle lineage identity
Joana Esteves de Lima, Reem Bou Akar, Léo Machado, Yuefeng Li, Bernadette Drayton-Libotte, F. Jeffrey Dilworth, Frédéric Relaix
Nat Commun. 2021; 12: 3450. Published online 2021 Jun 8. doi: 10.1038/s41467-021-23775-9
PMCID:
PMC8187366
AbstractArticlePDF–7.6M
11.
Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells
Samudyata, Paulo P. Amaral, Pär G. Engström, Samuel C. Robson, Michael L. Nielsen, Tony Kouzarides, Gonçalo Castelo-Branco
Exp Cell Res. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: Exp Cell Res. 2019 Aug 1; 381(1): 129–138. Published online 2019 May 9. doi: 10.1016/j.yexcr.2019.05.006
PMCID:
PMC6994247
AbstractArticlePDF–1.6M
12.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
13.
WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy
Meghna Kannan, Efil Bayam, Christel Wagner, Bruno Rinaldi, Perrine F. Kretz, Peggy Tilly, Marna Roos, Lara McGillewie, Séverine Bär, Shilpi Minocha, Claire Chevalier, Chrystelle Po, Sanger Mouse Genetics Project, Jamel Chelly, Jean-Louis Mandel, Renato Borgatti, Amélie Piton, Craig Kinnear, Ben Loos, David J. Adams, Yann Hérault, Stephan C. Collins, Sylvie Friant, Juliette D. Godin, Binnaz Yalcin
Proc Natl Acad Sci U S A. 2017 Oct 31; 114(44): E9308–E9317. Published online 2017 Oct 12. doi: 10.1073/pnas.1713625114
PMCID:
PMC5676932
AbstractArticlePDF–3.4M
14.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
15.
Histone chaperone HIRA regulates neural progenitor cell proliferation and neurogenesis via β-catenin
Yanxin Li, Jianwei Jiao
J Cell Biol. 2017 Jul 3; 216(7): 1975–1992. doi: 10.1083/jcb.201610014
PMCID:
PMC5496612
AbstractArticlePDF–3.6M
16.
Haploinsufficiency of the 22q11.2 microdeletion gene Mrpl40 disrupts short-term synaptic plasticity and working memory through dysregulation of mitochondrial calcium
P Devaraju, J Yu, D Eddins, M M Mellado-Lagarde, L R Earls, J J Westmoreland, G Quarato, D R Green, S S Zakharenko
Mol Psychiatry. 2017 Sep; 22(9): 1313–1326. Published online 2016 May 17. doi: 10.1038/mp.2016.75
PMCID:
PMC5114177
AbstractArticlePDF–963K
17.
HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3
Daniel Dilg, Rasha Noureldin M. Saleh, Sarah Elizabeth Lee Phelps, Yoann Rose, Laurent Dupays, Cian Murphy, Timothy Mohun, Robert H. Anderson, Peter J. Scambler, Ariane L. A. Chapgier
PLoS One. 2016; 11(8): e0161096. Published online 2016 Aug 12. doi: 10.1371/journal.pone.0161096
PMCID:
PMC4982693
AbstractArticlePDF–18M
18.
Cardiomyocyte-specific conditional knockout of the histone chaperone HIRA in mice results in hypertrophy, sarcolemmal damage and focal replacement fibrosis
Nicolas Valenzuela, Qiying Fan, Faisal Fa'ak, Benjamin Soibam, Harika Nagandla, Yu Liu, Robert J. Schwartz, Bradley K. McConnell, M. David Stewart
Dis Model Mech. 2016 Mar 1; 9(3): 335–345. doi: 10.1242/dmm.022889
PMCID:
PMC4833330
AbstractArticle
19.
Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks
Paulina A. Latos, Arnold R. Sienerth, Alexander Murray, Claire E. Senner, Masanaga Muto, Masahito Ikawa, David Oxley, Sarah Burge, Brian J. Cox, Myriam Hemberger
Genes Dev. 2015 Dec 1; 29(23): 2435–2448. doi: 10.1101/gad.268821.115
PMCID:
PMC4691948
AbstractArticlePDF–1.0M
20.
Continuous Histone Replacement by Hira Is Essential for Normal Transcriptional Regulation and De Novo DNA Methylation during Mouse Oogenesis
Buhe Nashun, Peter W.S. Hill, Sebastien A. Smallwood, Gopuraja Dharmalingam, Rachel Amouroux, Stephen J. Clark, Vineet Sharma, Elodie Ndjetehe, Pawel Pelczar, Richard J. Festenstein, Gavin Kelsey, Petra Hajkova
Mol Cell. 2015 Nov 19; 60(4): 611–625. doi: 10.1016/j.molcel.2015.10.010
PMCID:
PMC4672152
AbstractArticle

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