PMC Links for GEO Profiles (Select 125712656) - PMC

Result Filters

Links from GEO Profiles

Items: 1 to 20 of 137

<< First< Prev

Page of 7

Select item 114618551.

Transcriptional coactivator MED15 is required for beta cell maturation

Alex Z. Kadhim, Ben Vanderkruk, Samantha Mar, Meixia Dan, Katarina Zosel, Eric E. Xu, Rachel J. Spencer, Shugo Sasaki, Xuanjin Cheng, Shannon L. J. Sproul, Thilo Speckmann, Cuilan Nian, Robyn Cullen, Rocky Shi, Dan S. Luciani, Bradford G. Hoffman, Stefan Taubert, Francis C. Lynn

Nat Commun. 2024; 15: 8711. Published online 2024 Oct 8. doi: 10.1038/s41467-024-52801-9

PMCID:: PMC11461855

Abstract Article PDF–4.7M

Select item 112693032.

MicroRNA-7 regulates endocrine progenitor delamination and endocrine cell mass in developing pancreatic islets

Eva Kane, Tracy C.S. Mak, Mathieu Latreille

iScience. 2024 Jul 19; 27(7): 110332. Published online 2024 Jun 20. doi: 10.1016/j.isci.2024.110332

PMCID:: PMC11269303

Abstract Article PDF–5.7M

Select item 109453493.

NPC1 is required for postnatal islet β cell differentiation by maintaining mitochondria turnover

Bei Liu, Duanyi Hua, Linyan Shen, Tingting Li, Zheying Tao, Chenyang Fu, Zhongzheng Tang, Jie Yang, Li Zhang, Aifang Nie, Yiran Jiang, Jiqiu Wang, Yang Li, Yanyun Gu, Guang Ning

Theranostics. 2024; 14(5): 2058–2074. Published online 2024 Feb 24. doi: 10.7150/thno.90946

PMCID:: PMC10945349

Abstract Article PDF–9.7M

Select item 104824294.

Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation

Wilma Tixi, Maricela Maldonado, Ya-Ting Chang, Amy Chiu, Wilson Yeung, Nazia Parveen, Michael S Nelson, Ryan Hart, Shihao Wang, Wu Jih Hsu, Patrick Fueger, Janel L Kopp, Mark O Huising, Sangeeta Dhawan, Hung Ping Shih

eLife. 2023; 12: e90006. Published online 2023 Aug 23. doi: 10.7554/eLife.90006

PMCID:: PMC10482429

Abstract Article PDF–26M

Select item 104484745.

The SSBP3 co-regulator is required for glucose homeostasis, pancreatic islet architecture, and beta-cell identity

Eliana Toren, Jessica D. Kepple, Kristen V. Coutinho, Samuel O. Poole, Iztiba M. Deeba, Tanya H. Pierre, Yanping Liu, Maigen M. Bethea, Chad S. Hunter

Mol Metab. 2023 Oct; 76: 101785. Published online 2023 Aug 1. doi: 10.1016/j.molmet.2023.101785

PMCID:: PMC10448474

Abstract Article PDF–4.8M

Select item 103931936.

Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain

Vladimir Abarinov, Joshua A. Levine, Angela J. Churchill, Bryce Hopwood, Cailin S. Deiter, Michelle A. Guney, Kristen L. Wells, Jessica M. Schrunk, Yuchun Guo, Jennifer Hammelman, David K. Gifford, Mark A. Magnuson, Hynek Wichterle, Lori Sussel

Genes Dev. 2023 Jun 1; 37(11-12): 490–504. doi: 10.1101/gad.350569.123

PMCID:: PMC10393193

Abstract Article PDF–22M

Select item 101304877.

DNA Methylation–Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic β-Cell Heterogeneity

Nazia Parveen, Jean Kimi Wang, Supriyo Bhattacharya, Janielle Cuala, Mohan Singh Rajkumar, Alexandra E. Butler, Xiwei Wu, Hung-Ping Shih, Senta K. Georgia, Sangeeta Dhawan

Diabetes. 2023 May; 72(5): 575–589. Published online 2023 Jan 6. doi: 10.2337/db22-0506

Correction in:: Diabetes. 2023 Dec; 72(12): 1882.

PMCID:: PMC10130487

Abstract Article PDF–1.8M

Select item 98012198.

Inhibition of stearoyl-CoA desaturase 1 in the mouse impairs pancreatic islet morphogenesis and promotes loss of β-cell identity and α-cell expansion in the mature pancreas

Aneta M. Dobosz, Justyna Janikiewicz, Ewelina Krogulec, Anna Dziewulska, Anna Ajduk, Marcin Szpila, Hanna Nieznańska, Andrzej A. Szczepankiewicz, Dorota Wypych, Agnieszka Dobrzyn

Mol Metab. 2023 Jan; 67: 101659. Published online 2022 Dec 15. doi: 10.1016/j.molmet.2022.101659

PMCID:: PMC9801219

Abstract Article PDF–3.9M

Select item 94823369.

Focal adhesion kinase-mediated signaling controls the onset of pancreatic cell differentiation

Uylissa A. Rodriguez, Shakti Dahiya, Michelle L. Raymond, Chenxi Gao, Christina P. Martins-Cargill, Jon D. Piganelli, George K. Gittes, Jing Hu, Farzad Esni

Development. 2022 Sep 1; 149(17): dev200761. Published online 2022 Sep 9. doi: 10.1242/dev.200761

PMCID:: PMC9482336

Abstract Article

Select item 938722210.

MafB Maintains β-Cell Identity under MafA-Deficient Conditions

Zhaobin Deng, Akihiro Kuno, Masami Ojima, Satoru Takahashi

Mol Cell Biol. 2022 Aug; 42(8): e00541-21. Published online 2022 Jul 11. doi: 10.1128/mcb.00541-21

PMCID:: PMC9387222

Abstract Article PDF–3.3M

Select item 917449411.

Mafa-dependent GABAergic activity promotes mouse neonatal apneas

Laure Lecoin, Bowen Dempsey, Alexandra Garancher, Steeve Bourane, Pierre-Louis Ruffault, Marie-Pierre Morin-Surun, Nathalie Rocques, Martyn Goulding, Alain Eychène, Celio Pouponnot, Gilles Fortin, Jean Champagnat

Nat Commun. 2022; 13: 3284. Published online 2022 Jun 7. doi: 10.1038/s41467-022-30825-3

PMCID:: PMC9174494

Abstract Article PDF–3.2M

Select item 884512612.

Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males

Emily M. Walker, Jeeyeon Cha, Xin Tong, Min Guo, Jin-Hua Liu, Sophia Yu, Donato Iacovazzo, Franck Mauvais-Jarvis, Sarah E. Flanagan, Márta Korbonits, John Stafford, David A. Jacobson, Roland Stein

Cell Rep. Author manuscript; available in PMC 2022 Feb 15.

Published in final edited form as: Cell Rep. 2021 Oct 12; 37(2): 109813. doi: 10.1016/j.celrep.2021.109813

PMCID:: PMC8845126

Abstract Article PDF–2.8M

Select item 856590413.

Astrocytes contribute to pain gating in the spinal cord

Qian Xu, Neil C. Ford, Shaoqiu He, Qian Huang, Michael Anderson, Zhiyong Chen, Fei Yang, LaTasha K. Crawford, Michael J. Caterina, Yun Guan, Xinzhong Dong

Sci Adv. 2021 Nov; 7(45): eabi6287. Published online 2021 Nov 3. doi: 10.1126/sciadv.abi6287

PMCID:: PMC8565904

Abstract Article PDF–8.5M

Select item 851452314.

In vivo evaluation of GG2–GG1/A2 element activity in the insulin promoter region using the CRISPR–Cas9 system

Hirofumi Noguchi, Chika Miyagi-Shiohira, Takao Kinjo, Issei Saitoh, Masami Watanabe

Sci Rep. 2021; 11: 20290. Published online 2021 Oct 13. doi: 10.1038/s41598-021-99808-6

PMCID:: PMC8514523

Abstract Article PDF–3.5M

Select item 826883715.

NEUROD1 Is Required for the Early α and β Endocrine Differentiation in the Pancreas

Romana Bohuslavova, Ondrej Smolik, Jessica Malfatti, Zuzana Berkova, Zaneta Novakova, Frantisek Saudek, Gabriela Pavlinkova

Int J Mol Sci. 2021 Jul; 22(13): 6713. Published online 2021 Jun 23. doi: 10.3390/ijms22136713

PMCID:: PMC8268837

Abstract Article PDF–4.9M

Select item 825156216.

Insights into the etiology and physiopathology of MODY5/HNF1B pancreatic phenotype with a mouse model of the human disease

Evans Quilichini, Mélanie Fabre, Christoffer Nord, Thassadite Dirami, Axelle Le Marec, Silvia Cereghini, Raymond C Pasek, Maureen Gannon, Ulf Ahlgren, Cécile Haumaitre

J Pathol. 2021 May; 254(1): 31–45. Published online 2021 Mar 18. doi: 10.1002/path.5629

PMCID:: PMC8251562

Abstract Article PDF–46M

Select item 812647817.

Selective disruption of trigeminal sensory neurogenesis and differentiation in a mouse model of 22q11.2 deletion syndrome

Beverly A. Karpinski, Thomas M. Maynard, Corey A. Bryan, Gelila Yitsege, Anelia Horvath, Norman H. Lee, Sally A. Moody, Anthony-Samuel LaMantia

Dis Model Mech. 2022 Feb 1; 15(2): dmm047357. Published online 2021 May 4. doi: 10.1242/dmm.047357

PMCID:: PMC8126478

Abstract Article

Select item 805218618.

Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene

Ildem Akerman, Miguel Angel Maestro, Elisa De Franco, Vanessa Grau, Sarah Flanagan, Javier García-Hurtado, Gerhard Mittler, Philippe Ravassard, Lorenzo Piemonti, Sian Ellard, Andrew T. Hattersley, Jorge Ferrer

Cell Rep. 2021 Apr 13; 35(2): 108981. Published online 2021 Apr 13. doi: 10.1016/j.celrep.2021.108981

PMCID:: PMC8052186

Abstract Article

Select item 772079119.

A specialized niche in the pancreatic microenvironment promotes endocrine differentiation

Corinna Cozzitorto, Laura Mueller, Silvia Ruzittu, Nancy Mah, David Willnow, Jean-Francois Darrigrand, Heather Wilson, Daniel Khosravinia, Amir-Ala Mahmoud, Maurizio Risolino, Licia Selleri, Francesca M. Spagnoli

Dev Cell. Author manuscript; available in PMC 2021 Oct 26.

Published in final edited form as: Dev Cell. 2020 Oct 26; 55(2): 150–162.e6. Published online 2020 Aug 27. doi: 10.1016/j.devcel.2020.08.003

PMCID:: PMC7720791

Abstract Article PDF–2.7M

Select item 748040420.

A nutrient sensing transition at birth triggers glucose-responsive insulin secretion

Aharon Helman, Andrew L. Cangelosi, Jeffrey C. Davis, Quan Pham, Arielle Rothman, Aubrey L. Faust, Juerg R. Straubhaar, David M. Sabatini, Douglas A. Melton

Cell Metab. Author manuscript; available in PMC 2021 May 5.

Published in final edited form as: Cell Metab. 2020 May 5; 31(5): 1004–1016.e5. doi: 10.1016/j.cmet.2020.04.004