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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108474602.

GITRL impairs hepatocyte repopulation by liver progenitor cells to aggravate inflammation and fibrosis by GITR⁺CD8⁺ T lymphocytes in CDE Mice

Li Li, Yu He, Kai Liu, Lin Liu, Shan Shan, Helin Liu, Jiangbo Ren, Shujie Sun, Min Wang, Jidong Jia, Ping Wang

Cell Death Dis. 2024 Feb; 15(2): 114. Published online 2024 Feb 6. doi: 10.1038/s41419-024-06506-y

PMCID:: PMC10847460

Abstract Article PDF–6.8M

Select item 86096623.

Identification of Glucocorticoid-Induced TNF Receptor-Related Protein Ligand on Keratinocytes: Ligation by GITR Induces Keratinocyte Chemokine Production and Augments T-Cell Proliferation

Aideen M. Byrne, Elena Goleva, Donald Y.M. Leung

J Invest Dermatol. Author manuscript; available in PMC 2021 Nov 23.

Published in final edited form as: J Invest Dermatol. 2009 Dec; 129(12): 2784–2794. Published online 2009 Jun 18. doi: 10.1038/jid.2009.163

PMCID:: PMC8609662

Abstract Article PDF–1.6M

Select item 79255574.

Structures of mouse and human GITR–GITRL complexes reveal unique TNF superfamily interactions

Feng Wang, Bryant Chau, Sean M. West, Christopher R. Kimberlin, Fei Cao, Flavio Schwarz, Barbara Aguilar, Minhua Han, Winse Morishige, Christine Bee, Gavin Dollinger, Arvind Rajpal, Pavel Strop

Nat Commun. 2021; 12: 1378. Published online 2021 Mar 2. doi: 10.1038/s41467-021-21563-z

PMCID:: PMC7925557

Abstract Article PDF–2.3M

Select item 78692535.

GITRL on dendritic cells aggravates house dust mite-induced airway inflammation and airway hyperresponsiveness by modulating CD4⁺ T cell differentiation

Yaping Wang, Kou Liao, Bo Liu, Chao Niu, Wenjing Zou, Lili Yang, Ting Wang, Daiyin Tian, Zhengxiu Luo, Jihong Dai, Qubei Li, Enmei Liu, Caihui Gong, Zhou Fu, Ying Li, Fengxia Ding

Respir Res. 2021; 22: 46. Published online 2021 Feb 8. doi: 10.1186/s12931-020-01583-x

PMCID:: PMC7869253

Abstract Article PDF–9.6M

Select item 63315666.

Mature IgD^low/- B cells maintain tolerance by promoting regulatory T cell homeostasis

Avijit Ray, Mohamed I. Khalil, Kirthi L. Pulakanti, Robert T. Burns, Cody J. Gurski, Sreemanti Basu, Demin Wang, Sridhar Rao, Bonnie N. Dittel

Nat Commun. 2019; 10: 190. Published online 2019 Jan 14. doi: 10.1038/s41467-018-08122-9

PMCID:: PMC6331566

Abstract Article PDF–3.0M

Select item 44322817.

Macrophage-T Cell Interactions Mediate Neuropathic Pain through the Glucocorticoid-induced Tumor Necrosis Factor Ligand System

Yuka Kobayashi, Norikazu Kiguchi, Yohji Fukazawa, Fumihiro Saika, Takehiko Maeda, Shiroh Kishioka

J Biol Chem. 2015 May 15; 290(20): 12603–12613. Published online 2015 Mar 18. doi: 10.1074/jbc.M115.636506

PMCID:: PMC4432281

Abstract Article PDF–3.8M

Select item 41408018.

Increased Antigen Presentation but Impaired T Cells Priming after Upregulation of Interferon-Beta Induced by Lipopolysaccharides Is Mediated by Upregulation of B7H1 and GITRL

Fang Wang, Yan Yan Wang, Juan Li, Xiang You, Xin Hui Qiu, Yi Nan Wang, Feng Guang Gao

PLoS One. 2014; 9(8): e105636. Published online 2014 Aug 21. doi: 10.1371/journal.pone.0105636

Correction in:: PLoS One. 2014; 9(9): e108120.

PMCID:: PMC4140801

Abstract Article PDF–1.3M

Select item 39649559.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 386882610.

Glucocorticoid-induced TNF receptor family-related protein ligand regulates the migration of monocytes to the inflamed intestine

Gongxian Liao, Boaz van Driel, Erica Magelky, Michael S. O'Keeffe, Rene de Waal Malefyt, Pablo Engel, Roland W. Herzog, Emiko Mizoguchi, Atul K. Bhan, Cox Terhorst

FASEB J. 2014 Jan; 28(1): 474–484. doi: 10.1096/fj.13-236505

PMCID:: PMC3868826

Abstract Article

Select item 340737011.

Th2 responses to helminth parasites can be therapeutically enhanced by, but are not dependent upon, GITR-GITRL co-stimulation in vivo¹

Nienke van der Werf, Stephen A. Redpath, Alexander T. Phythian-Adams, Miyuki Azuma, Judith E. Allen, Rick M. Maizels, Andrew S. MacDonald, Matthew D. Taylor

J Immunol. Author manuscript; available in PMC 2012 Jul 28.

Published in final edited form as: J Immunol. 2011 Aug 1; 187(3): 1411–1420. Published online 2011 Jun 24. doi: 10.4049/jimmunol.1100834

PMCID:: PMC3407370

Abstract Article PDF–1.0M

Select item 331174312.

A Novel IL-10-Independent Regulatory Role for B Cells in Suppressing Autoimmunity by Maintenance of Regulatory T Cells via GITRL

Avijit Ray, Sreemanti Basu, Calvin Williams, Nita Salzman, Bonnie N. Dittel

J Immunol. Author manuscript; available in PMC 2013 Apr 1.

Published in final edited form as: J Immunol. 2012 Apr 1; 188(7): 3188–3198. Published online 2012 Feb 24. doi: 10.4049/jimmunol.1103354

PMCID:: PMC3311743

Abstract Article PDF–2.0M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 305533914.

Neutralization of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Reduces Spinal Cord Injury Damage in Mice

Giuseppina Cantarella, Giulia Di Benedetto, Mimmo Scollo, Irene Paterniti, Salvatore Cuzzocrea, Paolo Bosco, Giuseppe Nocentini, Carlo Riccardi, Renato Bernardini

Neuropsychopharmacology. 2010 May; 35(6): 1302–1314. Published online 2010 Jan 27. doi: 10.1038/npp.2009.234

Correction in:: Neuropsychopharmacology. 2024 May; 49(6): 1061–1062.

PMCID:: PMC3055339

Abstract Article PDF–1.0M

Select item 302253415.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 293558416.

Blockade of GITR–GITRL interaction maintains Treg function to prolong allograft survival

James I. Kim, Samsher B. Sonawane, Major K. Lee, Seoung-Hoon Lee, Patrick E. Duff, Daniel J. Moore, Matthew R. O’Connor, Moh-Moh Lian, Shaoping Deng, Yongwon Choi, Heidi Yeh, Andrew J. Caton, James F. Markmann

Eur J Immunol. Author manuscript; available in PMC 2010 Sep 8.

Published in final edited form as: Eur J Immunol. 2010 May; 40(5): 1369–1374. doi: 10.1002/eji.200940046

PMCID:: PMC2935584

Abstract Article PDF–157K

Select item 282272017.

Localized expression of GITR-L in the tumor microenvironment promotes CD8⁺ T cell dependent anti-tumor immunity

John S. Cho, Jeffrey V. Hsu, Sherie L. Morrison

Cancer Immunol Immunother. 2009 Jul; 58(7): 1057–1069. Published online 2008 Nov 19. doi: 10.1007/s00262-008-0622-2

PMCID:: PMC2822720

Abstract Article PDF–753K

Select item 277564018.

Key Role of the GITR/GITRLigand Pathway in the Development of Murine Autoimmune Diabetes: A Potential Therapeutic Target

Sylvaine You, Lynn Poulton, Steve Cobbold, Chih-Pin Liu, Michael Rosenzweig, Douglas Ringler, Wen-Hui Lee, Berta Segovia, Jean-François Bach, Herman Waldmann, Lucienne Chatenoud

PLoS One. 2009; 4(11): e7848. Published online 2009 Nov 20. doi: 10.1371/journal.pone.0007848

PMCID:: PMC2775640

Abstract Article PDF–1004K

Select item 272952619.

Enhancement of T-cell-mediated anti-tumour immunity via the ectopically expressed glucocorticoid-induced tumour necrosis factor receptor-related receptor ligand (GITRL) on tumours

Jinhua Piao, Yosuke Kamimura, Hideyuki Iwai, Yujia Cao, Keisuke Kikuchi, Masaaki Hashiguchi, Taro Masunaga, Hongsi Jiang, Kouichi Tamura, Shimon Sakaguchi, Miyuki Azuma

Immunology. 2009 Aug; 127(4): 489–499. doi: 10.1111/j.1365-2567.2008.03036.x

PMCID:: PMC2729526

Abstract Article PDF–562K

Select item 267281520.

1.8 Å structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells

Kausik Chattopadhyay, Udupi A. Ramagopal, Stanley G. Nathenson, Steven C. Almo

Acta Crystallogr D Biol Crystallogr. 2009 May 1; 65(Pt 5): 434–439. Published online 2009 Apr 18. doi: 10.1107/S0907444909005721

PMCID:: PMC2672815

Abstract Article PDF–707K

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