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Select item 105057321.

Testis exposure to unopposed/elevated activin A in utero affects somatic and germ cells and alters steroid levels mimicking phthalate exposure

Penny A. F. Whiley, Michael C. M. Luu, Liza O’Donnell, David J. Handelsman, Kate L. Loveland

Front Endocrinol (Lausanne) 2023; 14: 1234712. Published online 2023 Sep 1. doi: 10.3389/fendo.2023.1234712

PMCID:: PMC10505732

Abstract Article PDF–9.9M

Select item 93277372.

Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice

Esteban Salazar-Petres, Daniela Pereira-Carvalho, Jorge Lopez-Tello, Amanda Nancy Sferruzzi-Perri

Biol Reprod. 2022 Jun; 106(6): 1292–1311. Published online 2022 Mar 16. doi: 10.1093/biolre/ioac056

PMCID:: PMC9327737

Abstract Article PDF–3.0M

Select item 79887753.

Pre-locus coeruleus neurons in rat and mouse

Silvia Gasparini, Jon M. Resch, Anuradha M. Gore, Lila Peltekian, Joel C. Geerling

Am J Physiol Regul Integr Comp Physiol. 2021 Mar 1; 320(3): R342–R361. Published online 2020 Dec 9. doi: 10.1152/ajpregu.00261.2020

PMCID:: PMC7988775

Abstract Article

Select item 65038514.

Cilia-associated oxysterols activate Smoothened

David R. Raleigh, Navdar Sever, Pervinder K. Choksi, Monika Abedin Sigg, Kelly M. Hines, Bonne M. Thompson, Daniel Elnatan, Priyadarshini Jaishankar, Paola Bisignano, Francesc R. Garcia-Gonzalo, Alexis Leigh Krup, Markus Eberl, Sunny Y. Wong, Adam R. Renslo, Michael Grabe, Jeffrey G. McDonald, Libin Xu, Philip A. Beachy, Jeremy F. Reiter

Mol Cell. Author manuscript; available in PMC 2019 May 7.

Published in final edited form as: Mol Cell. 2018 Oct 18; 72(2): 316–327.e5. doi: 10.1016/j.molcel.2018.08.034

PMCID:: PMC6503851

Abstract Article PDF–1.9M

Select item 64453565.

The Mother or the Fetus? 11β-Hydroxysteroid Dehydrogenase Type 2 Null Mice Provide Evidence for Direct Fetal Programming of Behavior by Endogenous Glucocorticoids

Megan C. Holmes, Christian T. Abrahamsen, Karen L. French, Janice M. Paterson, John J. Mullins, Jonathan R. Seckl

J Neurosci. 2006 Apr 5; 26(14): 3840–3844. doi: 10.1523/JNEUROSCI.4464-05.2006

PMCID:: PMC6445356

Abstract Article PDF–234K

Select item 64430406.

11ß-Hydroxysteroid Dehydrogenase Type 2 Protects the Neonatal Cerebellum From Deleterious Effects of Glucocorticoids

M. C. Holmes, M. Sangra, K. L. French, I. R. Whittle, J. Paterson, J. J. Mullins, J. R. Seckl

Neuroscience. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Neuroscience. 2006 Feb; 137(3): 865–873. Published online 2005 Nov 14. doi: 10.1016/j.neuroscience.2005.09.037

PMCID:: PMC6443040

Abstract Article PDF–1.9M

Select item 64351877.

Alterered Placental Function of 11β-HSD2 Knockout Mice

Caitlin S Wyrwoll, Jonathan R Seckl, Megan C Holmes

Endocrinology. Author manuscript; available in PMC 2019 Mar 26.

Published in final edited form as: Endocrinology. 2009 Mar; 150(3): 1287–1293. Published online 2008 Oct 9. doi: 10.1210/en.2008-1100

PMCID:: PMC6435187

Abstract Article PDF–954K

Select item 63690138.

Aldosterone-sensitive HSD2 neurons in mice

Silvia Gasparini, Jon M. Resch, Sowmya V. Narayan, Lila Peltekian, Gabrielle N. Iverson, Samyukta Karthik, Joel C. Geerling

Brain Struct Funct. Author manuscript; available in PMC 2020 Jan 1.

Published in final edited form as: Brain Struct Funct. 2019 Jan; 224(1): 387–417. Published online 2018 Oct 20. doi: 10.1007/s00429-018-1778-y

PMCID:: PMC6369013

Abstract Article PDF–3.8M

Select item 60786429.

Myeloid cells are capable of synthesizing aldosterone to exacerbate damage in muscular dystrophy

Jessica A. Chadwick, Sarah A. Swager, Jeovanna Lowe, Steven S. Welc, James G. Tidball, Celso E. Gomez-Sanchez, Elise P. Gomez-Sanchez, Jill A. Rafael-Fortney

Hum Mol Genet. 2016 Dec 1; 25(23): 5167–5177. Published online 2016 Oct 23. doi: 10.1093/hmg/ddw331

PMCID:: PMC6078642

Abstract Article PDF–668K

Select item 563745410.

Aldosterone-Sensing Neurons in the NTS Exhibit State-Dependent Pacemaker Activity and Drive Sodium Appetite via Synergy with Angiotensin II Signaling

Jon M. Resch, Henning Fenselau, Joseph C. Madara, Chen Wu, John N. Campbell, Anna Lyubetskaya, Brian A. Dawes, Linus T. Tsai, Monica M. Li, Yoav Livneh, Qingen Ke, Peter M. Kang, Géza Fejes-Tóth, Anikó Náray-Fejes-Tóth, Joel C. Geerling, Bradford B. Lowell

Neuron. Author manuscript; available in PMC 2018 Sep 27.

Published in final edited form as: Neuron. 2017 Sep 27; 96(1): 190–206.e7. doi: 10.1016/j.neuron.2017.09.014

PMCID:: PMC5637454

Abstract Article PDF–2.9M

Select item 541805211.

Rac1 GTPase regulates 11β hydroxysteroid dehydrogenase type 2 and fibrotic remodeling

Daniel Lavall, Pia Schuster, Nadine Jacobs, Andrey Kazakov, Michael Böhm, Ulrich Laufs

J Biol Chem. 2017 May 5; 292(18): 7542–7553. Published online 2017 Mar 20. doi: 10.1074/jbc.M116.764449

PMCID:: PMC5418052

Abstract Article PDF–2.3M

Select item 504200412.

Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles

Anja E. Eisenhardt, Adrian Sprenger, Michael Röring, Ricarda Herr, Florian Weinberg, Martin Köhler, Sandra Braun, Joachim Orth, Britta Diedrich, Ulrike Lanner, Natalja Tscherwinski, Simon Schuster, Nicolas Dumaz, Enrico Schmidt, Ralf Baumeister, Andreas Schlosser, Jörn Dengjel, Tilman Brummer

Oncotarget. 2016 May 3; 7(18): 26628–26652. Published online 2016 Mar 28. doi: 10.18632/oncotarget.8427

PMCID:: PMC5042004

Abstract Article PDF–7.5M

Select item 483039913.

Hsd11b2 HAPLOINSUFFICIENCY IN MICE CAUSES SALT-SENSITIVITY OF BLOOD PRESSURE

Matthew A. Bailey, Eilidh Craigie, Dawn E.W. Livingstone, Yuri V. Kotelevtsev, Emad A.S. Al-Dujaili, Christopher J. Kenyon, John J. Mullins

Hypertension. Author manuscript; available in PMC 2016 Apr 13.

Published in final edited form as: Hypertension. 2011 Mar; 57(3): 515–520. Published online 2011 Jan 31. doi: 10.1161/HYPERTENSIONAHA.110.163782

PMCID:: PMC4830399

Abstract Article PDF–589K

Select item 481977214.

Conditional Deletion of Hsd11b2 in the Brain Causes Salt Appetite and Hypertension

Louise C. Evans, Jessica R. Ivy, Caitlin Wyrwoll, Julie A. McNairn, Robert I. Menzies, Thorbjørn H. Christensen, Emad A.S. Al-Dujaili, Christopher J. Kenyon, John J. Mullins, Jonathan R. Seckl, Megan C. Holmes, Matthew A. Bailey

Circulation. 2016 Apr 5; 133(14): 1360–1370. Published online 2016 Apr 4. doi: 10.1161/CIRCULATIONAHA.115.019341

PMCID:: PMC4819772

Abstract Article PDF–863K

Select item 444426015.

Inhibition of 11β-Hydroxysteroid Dehydrogenase Type II Suppresses Lung Carcinogenesis by Blocking Tumor COX-2 Expression as Well as the ERK and mTOR Signaling Pathways

Jian Chang, Min Xue, Shilin Yang, Bing Yao, Bixiang Zhang, Xiaoping Chen, Ambra Pozzi, Ming-Zhi Zhang

PLoS One. 2015; 10(5): e0127030. Published online 2015 May 26. doi: 10.1371/journal.pone.0127030

PMCID:: PMC4444260

Abstract Article PDF–13M

Select item 418981916.

Genome-wide microarray comparison reveals downstream genes of Pax6 in the developing mouse cerebellum

Thomas J. Ha, Douglas J. Swanson, Roumyana Kirova, Joanna Yeung, Kunho Choi, Yiai Tong, Elissa J. Chesler, Daniel Goldowitz

Eur J Neurosci. Author manuscript; available in PMC 2014 Oct 8.

Published in final edited form as: Eur J Neurosci. 2012 Oct; 36(7): 2888–2898. Published online 2012 Jul 22. doi: 10.1111/j.1460-9568.2012.08221.x

PMCID:: PMC4189819

Abstract Article PDF–1.4M

Select item 397704217.

11β-hydroxysteroid dehydrogenase type 2 deficiency accelerates atherogenesis and causes pro-inflammatory changes in the endothelium in Apoe^−/− mice

Graeme A Deuchar, Danielle McLean, Patrick W.F. Hadoke, David G Brownstein, David J Webb, John J Mullins, Karen Chapman, Jonathan R Seckl, Yuri V Kotelevtsev

Endocrinology. Author manuscript; available in PMC 2014 Apr 7.

Published in final edited form as: Endocrinology. 2011 Jan; 152(1): 236–246. Published online 2010 Nov 24. doi: 10.1210/en.2010-0925

PMCID:: PMC3977042

Abstract Article PDF–4.9M

Select item 397704118.

Contribution of endogenous glucocorticoids and their intra-vascular metabolism by 11β-HSDs to post-angioplasty neointimal proliferation in mice

Javaid Iqbal, Linsay J Macdonald, Lucinda Low, Jonathan R. Seckl, Christopher W Yau, Brian R Walker, Patrick WF Hadoke

Endocrinology. Author manuscript; available in PMC 2014 Apr 7.

Published in final edited form as: Endocrinology. 2012 Dec; 153(12): 5896–5905. Published online 2012 Nov 2. doi: 10.1210/en.2012-1481

PMCID:: PMC3977041

Abstract Article PDF–1.1M

Select item 394491619.

Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20α-hydroxysteroid dehydrogenase in the mouse lung

Eric Boucher, Pierre R Provost, Yves Tremblay

BMC Res Notes. 2014; 7: 119. Published online 2014 Mar 1. doi: 10.1186/1756-0500-7-119

PMCID:: PMC3944916

Abstract Article PDF–844K

Select item 377807320.

Epithelial 11β-hydroxysteroid dehydrogenase type II deletion inhibits Apc^+/min mouse tumorigenesis via COX-2 pathway inhibition and induction of G1 cell cycle arrest

Li Jiang, Shilin Yang, Huiyong Yin, Xiaofeng Fan, Suwan Wang, Bing Yao, Ambra Pozzi, Xiaoping Chen, Raymond C Harris, Ming-Zhi Zhang

Mol Cancer Res. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Mol Cancer Res. 2013 Sep; 11(9): 1040–1050. Published online 2013 Jun 5. doi: 10.1158/1541-7786.MCR-13-0084-T

PMCID:: PMC3778073

Abstract Article PDF–2.2M

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