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Select item 115396191.

SARS-CoV-2 nucleocapsid protein interaction with YBX1 displays oncolytic properties through PKM mRNA destabilization

Xin Chen, Baohong Jiang, Yu Gu, Zhaoyang Yue, Ying Liu, Zhiwei Lei, Ge Yang, Minhua Deng, Xuelong Zhang, Zhen Luo, Yongkui Li, Qiwei Zhang, Xuepei Zhang, Jianguo Wu, Chunyu Huang, Pan Pan, Fangjian Zhou, Ning Wang

Mol Cancer. 2024; 23: 248. Published online 2024 Nov 6. doi: 10.1186/s12943-024-02153-1

PMCID:: PMC11539619

Abstract Article PDF–11M

Select item 114472562.

Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure

Andrew R. M. Michael, Bruno C. Amaral, Kallie L. Ball, Kristen H. Eiriksson, David C. Schriemer

Nat Commun. 2024; 15: 8537. Published online 2024 Oct 2. doi: 10.1038/s41467-024-52844-y

PMCID:: PMC11447256

Abstract Article PDF–2.8M

Select item 113735993.

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway

Elena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, Tatiana Varanita, Magdalena Bachmann, Margherita Festa, Daniele Bonesso, Mireia Perez-Verdaguer, Andrea Carrer, Angelo Velle, Roberta Peruzzo, Silvia Muccioli, Davide Doni, Luigi Leanza, Paola Costantini, Frank Stein, Mandy Rettel, Antonio Felipe, Michael J. Edwards, Erich Gulbins, Laura Cendron, Chiara Romualdi, Vanessa Checchetto, Ildiko Szabo

Sci Adv. 2024 Sep 6; 10(36): eadn9361. Published online 2024 Sep 4. doi: 10.1126/sciadv.adn9361

PMCID:: PMC11373599

Abstract Article PDF–11M

Select item 113691744.

Proteome-scale characterisation of motif-based interactome rewiring by disease mutations

Johanna Kliche, Leandro Simonetti, Izabella Krystkowiak, Hanna Kuss, Marcel Diallo, Emma Rask, Jakob Nilsson, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2024 Sep; 20(9): 1025–1048. Published online 2024 Jul 15. doi: 10.1038/s44320-024-00055-4

PMCID:: PMC11369174

Abstract Article PDF–2.7M

Select item 113113715.

The Aryl Hydrocarbon Receptor Regulates Invasiveness and Motility in Acute Myeloid Leukemia Cells through Expressional Regulation of Non-Muscle Myosin Heavy Chain IIA

Fengjiao Chang, Lele Wang, Youngjoon Kim, Minkyoung Kim, Sunwoo Lee, Sang-woo Lee

Int J Mol Sci. 2024 Aug; 25(15): 8147. Published online 2024 Jul 26. doi: 10.3390/ijms25158147

PMCID:: PMC11311371

Abstract Article PDF–3.2M

Select item 112969146.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 112099357.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111881838.

A novel role for KIFC1-MYH9 interaction in triple-negative breast cancer aggressiveness and racial disparity

Chakravarthy Garlapati, Shriya Joshi, Chunhua Yang, Darshan Shimoga Chandrashekar, Padmashree Rida, Ritu Aneja

Cell Commun Signal. 2024; 22: 312. Published online 2024 Jun 6. doi: 10.1186/s12964-024-01664-0

PMCID:: PMC11188183

Abstract Article PDF–12M

Select item 109495989.

TMEM120B strengthens breast cancer cell stemness and accelerates chemotherapy resistance via β1-integrin/FAK-TAZ-mTOR signaling axis by binding to MYH9

Ran Hu, Yu Cao, Yuanyuan Wang, Tingting Zhao, Kaibo Yang, Mingwei Fan, Mengyao Guan, Yuekang Hou, Jiao Ying, Xiaowen Ma, Ning Deng, Xun Sun, Yong Zhang, Xiupeng Zhang

Breast Cancer Res. 2024; 26: 48. Published online 2024 Mar 19. doi: 10.1186/s13058-024-01802-z

PMCID:: PMC10949598

Abstract Article PDF–16M

Select item 1078754210.

Chromatin accessibility complex subunit 1 enhances tumor growth by regulating the oncogenic transcription of YAP in breast and cervical cancer

Shasha Li, Lulu Wang, Jing Shi, Yi Chen, Ang Xiao, Bingyue Huo, Wenjing Tian, Shilu Zhang, Gang Yang, Wensheng Gong, Huixia Zhang

PeerJ. 2024; 12: e16752. Published online 2024 Jan 10. doi: 10.7717/peerj.16752

PMCID:: PMC10787542

Abstract Article PDF–13M

Select item 1077075511.

Effects of specific disease mutations in non-muscle myosin 2A on its structure and function

David Casas-Mao, Glenn Carrington, Marta Giralt Pujol, Michelle Peckham

J Biol Chem. 2024 Jan; 300(1): 105514. Published online 2023 Nov 30. doi: 10.1016/j.jbc.2023.105514

PMCID:: PMC10770755

Abstract Article PDF–3.9M

Select item 1076495812.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 1064152413.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 1061767314.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 1051509215.

St3gal1 and βII-spectrin pathways control CAR-T cell migration to target tumor sites

Yeonsun Hong, Brandon L. Walling, Hye-Ran Kim, William S. Serratelli, John R. Lozada, Cooper J. Sailer, Andrea M. Amitrano, Kihong Lim, Raj Kumar Mongre, Kyun-Do Kim, Tara Capece, Elena B. Lomakina, Nicholas S. Reilly, Kevin Vo, Scott A. Gerber, Tan-Chi Fan, Alice Lin-Tsing Yu, Patrick W. Oakes, Richard E. Waugh, Chang-Duk Jun, Patrick M. Reagan, Minsoo Kim

Nat Immunol. Author manuscript; available in PMC 2023 Sep 22.

Published in final edited form as: Nat Immunol. 2023 Jun; 24(6): 1007–1019. Published online 2023 Apr 17. doi: 10.1038/s41590-023-01498-x

PMCID:: PMC10515092

Abstract Article PDF–4.3M

Select item 1050093816.

SARS-CoV-2 viral genes Nsp6, Nsp8, and M compromise cellular ATP levels to impair survival and function of human pluripotent stem cell-derived cardiomyocytes

Juli Liu, Shiyong Wu, Yucheng Zhang, Cheng Wang, Sheng Liu, Jun Wan, Lei Yang

Stem Cell Res Ther. 2023; 14: 249. Published online 2023 Sep 13. doi: 10.1186/s13287-023-03485-3

PMCID:: PMC10500938

Abstract Article PDF–5.0M

Select item 1048031717.

A brain specific alternatively spliced isoform of nonmuscle myosin IIA lacks its mechanoenzymatic activities

Samprita Das, Ditipriya Mallick, Sourav Sarkar, Neil Billington, James R. Sellers, Siddhartha S. Jana

J Biol Chem. 2023 Sep; 299(9): 105143. Published online 2023 Aug 9. doi: 10.1016/j.jbc.2023.105143

PMCID:: PMC10480317

Abstract Article PDF–2.2M

Select item 1046271118.

SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication

Augusto C. Montezano, Livia L. Camargo, Sheon Mary, Karla B Neves, Francisco J Rios, Ross Stein, Rheure A. Lopes, Wendy Beattie, Jacqueline Thomson, Vanessa Herder, Agnieszka M. Szemiel, Steven McFarlane, Massimo Palmarini, Rhian M. Touyz

Sci Rep. 2023; 13: 14086. Published online 2023 Aug 28. doi: 10.1038/s41598-023-41115-3

PMCID:: PMC10462711

Abstract Article PDF–1.3M

Select item 1046073219.

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4

Wenhu Chen, Liqiang Hu, Xuemei Lu, Xiaofei Wang, Changan Zhao, Chen Guo, Xiaoyan Li, Yuqin Ding, Hongguang Zhao, Dongdong Tong, Lifang Wang, Chen Huang

Breast Cancer Res Treat. 2023; 201(3): 353–366. Published online 2023 Jul 11. doi: 10.1007/s10549-023-07028-5

PMCID:: PMC10460732

Abstract Article PDF–5.6M

Select item 1028411720.

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry

Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2023 Jun 21.

Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986

PMCID:: PMC10284117

Abstract Article PDF–2.5M

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