PMC Links for GEO Profiles (Select 124520678) - PMC

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 85215614.

CRISPR/Cas9-mediated knockout of PIM3 suppresses tumorigenesis and cancer cell stemness in human hepatoblastoma cells

Raoud Marayati, Laura L. Stafman, Adele P. Williams, Laura V. Bownes, Colin H. Quinn, Hooper R. Markert, Juliet L. Easlick, Jerry E. Stewart, David K. Crossman, Elizabeth Mroczek-Musulman, Elizabeth A. Beierle

Cancer Gene Ther. Author manuscript; available in PMC 2022 May 19.

Published in final edited form as: Cancer Gene Ther. 2022 May; 29(5): 558–572. Published online 2021 Apr 16. doi: 10.1038/s41417-021-00334-4

PMCID:: PMC8521561

Abstract Article PDF–1.8M

Select item 75668815.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 74273276.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 73959167.

High Expression of NEK2 and PIM1, but Not PIM3, Is Linked to an Aggressive Phenotype of Bronchopulmonary Neuroendocrine Neoplasms

Ewelina Motylewska, Marcin Braun, Henryk Stępień

Endocr Pathol. 2020; 31(3): 264–273. Published online 2020 Jun 5. doi: 10.1007/s12022-020-09629-y

PMCID:: PMC7395916

Abstract Article PDF–5.1M

Select item 73220678.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 64790529.

PIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation

Kei Miyakawa, Satoko Matsunaga, Masaru Yokoyama, Masako Nomaguchi, Yayoi Kimura, Mayuko Nishi, Hirokazu Kimura, Hironori Sato, Hisashi Hirano, Tomohiko Tamura, Hirofumi Akari, Tomoyuki Miura, Akio Adachi, Tatsuya Sawasaki, Naoki Yamamoto, Akihide Ryo

Nat Commun. 2019; 10: 1844. Published online 2019 Apr 23. doi: 10.1038/s41467-019-09867-7

PMCID:: PMC6479052

Abstract Article PDF–1.8M

Select item 570101310.

mTORC1 suppresses PIM3 expression via miR-33 encoded by the SREBP loci

Ilana Kelsey, Marie Zbinden, Vanessa Byles, Margaret Torrence, Brendan D. Manning

Sci Rep. 2017; 7: 16112. Published online 2017 Nov 23. doi: 10.1038/s41598-017-16398-y

PMCID:: PMC5701013

Abstract Article PDF–2.2M

Select item 534238911.

PIM kinases as therapeutic targets against advanced melanoma

Batool Shannan, Andrea Watters, Quan Chen, Stefan Mollin, Markus Dörr, Eric Meggers, Xiaowei Xu, Phyllis A. Gimotty, Michela Perego, Ling Li, Joseph Benci, Clemens Krepler, Patricia Brafford, Jie Zhang, Zhi Wei, Gao Zhang, Qin Liu, Xiangfan Yin, Katherine L. Nathanson, Meenhard Herlyn, Adina Vultur

Oncotarget. 2016 Aug 23; 7(34): 54897–54912. Published online 2016 Jul 19. doi: 10.18632/oncotarget.10703

PMCID:: PMC5342389

Abstract Article PDF–8.2M

Select item 510837012.

Pim-3 is a Critical Risk Factor in Development and Prognosis of Prostate Cancer

Yanchun Qu, Changwen Zhang, E Du, Andi Wang, Yuming Yang, Jianing Guo, Aixiang Wang, Zhihong Zhang, Yong Xu

Med Sci Monit. 2016; 22: 4254–4260. Published online 2016 Nov 9. doi: 10.12659/MSM.898223

PMCID:: PMC5108370

Abstract Article PDF–445K

Select item 446784613.

Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts

Niina M. Santio, Sini K. Eerola, Ilkka Paatero, Jari Yli-Kauhaluoma, Fabrice Anizon, Pascale Moreau, Johanna Tuomela, Pirkko Härkönen, Päivi J. Koskinen

PLoS One. 2015; 10(6): e0130340. Published online 2015 Jun 15. doi: 10.1371/journal.pone.0130340

PMCID:: PMC4467846

Abstract Article PDF–13M

Select item 422670014.

The PIM family of oncoproteins: Small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets

Kumar Saurabh, Michael T. Scherzer, Parag P. Shah, Alice S. Mims, William W. Lockwood, Andrew S. Kraft, Levi J. Beverly

Oncotarget. 2014 Sep; 5(18): 8503–8514. Published online 2014 Aug 13. doi: 10.18632/oncotarget.2330

PMCID:: PMC4226700

Abstract Article PDF–5.4M

Select item 389478615.

Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

Mikko Taipale, Irina Krykbaeva, Martina Koeva, Can Kayatekin, Kenneth D. Westover, Georgios I. Karras, Susan Lindquist

Cell. Author manuscript; available in PMC 2014 Jan 17.

Published in final edited form as: Cell. 2012 Aug 31; 150(5): 987–1001. doi: 10.1016/j.cell.2012.06.047

PMCID:: PMC3894786

Abstract Article PDF–5.0M

Select item 388763216.

Pim Protein Kinase-3 Is Regulated by TNF-α and Promotes Endothelial Cell Sprouting

Handong Yang, Yinfang Wang, Hang Qian, Peng Zhang, Congxin Huang

Mol Cells. 2011 Sep 30; 32(3): 235–241. doi: 10.1007/s10059-011-1026-z

PMCID:: PMC3887632

Abstract Article PDF–753K

Select item 381356517.

Inhibition of oncogenic Pim-3 kinase modulates transformed growth and chemosensitizes pancreatic cancer cells to gemcitabine

Dapeng Xu, Michael G. Cobb, Lily Gavilano, Sam M. Witherspoon, Daniel Williams, Catherine D. White, Pietro Taverna, Brian K. Bednarski, Hong Jin Kim, Albert S. Baldwin, Antonio T. Baines

Cancer Biol Ther. 2013 Jun 1; 14(6): 492–501. Published online 2013 Apr 10. doi: 10.4161/cbt.24343

PMCID:: PMC3813565

Abstract Article PDF–2.0M

Select item 356152918.

Proviral Integration Site for Moloney Murine Leukemia Virus (PIM) Kinases Promote Human T Helper 1 Cell Differentiation

Johanna Tahvanainen, Minna K. Kyläniemi, Kartiek Kanduri, Bhawna Gupta, Hanna Lähteenmäki, Teemu Kallonen, Anna Rajavuori, Omid Rasool, Päivi J. Koskinen, Kanury V. S. Rao, Harri Lähdesmäki, Riitta Lahesmaa

J Biol Chem. 2013 Feb 1; 288(5): 3048–3058. Published online 2012 Dec 3. doi: 10.1074/jbc.M112.361709

PMCID:: PMC3561529

Abstract Article PDF–1.3M

Select item 324820419.

The direct Myc target Pim3 cooperates with other Pim kinases in supporting viability of Myc-induced B-cell lymphomas

Linus Plym Forshell, Yongmei Li, Tacha Zi Plym Forshell, Martina Rudelius, Lisa Nilsson, Ulrich Keller, Jonas Nilsson

Oncotarget. 2011 Jun; 2(6): 448–460. Published online 2011 Jun 5. doi: 10.18632/oncotarget.283

PMCID:: PMC3248204

Abstract Article PDF–1.8M

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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