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Items: 1 to 20 of 28

1.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
2.
Genetic Analysis of Hyperpolarization‐Activated Cyclic Nucleotide‐Gated Cation Channels in Sudden Unexpected Death in Epilepsy Cases
Emily Tu, Louise Waterhouse, Johan Duflou, Richard D. Bagnall, Christopher Semsarian
Brain Pathol. 2011 Nov; 21(6): 692–698. Published online 2011 Aug 16. doi: 10.1111/j.1750-3639.2011.00500.x
PMCID:
PMC8094053
AbstractArticlePDF–332K
3.
Recessive Loss-of-Function Mutation in the Pacemaker HCN2 Channel Causing Increased Neuronal Excitability in a Patient with Idiopathic Generalized Epilepsy
Jacopo C. DiFrancesco, Andrea Barbuti, Raffaella Milanesi, Stefania Coco, Annalisa Bucchi, Georgia Bottelli, Carlo Ferrarese, Silvana Franceschetti, Benedetta Terragni, Mirko Baruscotti, Dario DiFrancesco
J Neurosci. 2011 Nov 30; 31(48): 17327–17337. doi: 10.1523/JNEUROSCI.3727-11.2011
PMCID:
PMC6623833
AbstractArticlePDF–2.6M
4.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
5.
Mechanism for the inhibition of the cAMP dependence of HCN ion channels by the auxiliary subunit TRIP8b
John R. Bankston, Hannah A. DeBerg, Stefan Stoll, William N. Zagotta
J Biol Chem. 2017 Oct 27; 292(43): 17794–17803. Published online 2017 Sep 1. doi: 10.1074/jbc.M117.800722
PMCID:
PMC5663879
AbstractArticlePDF–1.5M
6.
HCN2/SkM1 Gene Transfer Into Canine Left Bundle Branch Induces Stable, Autonomically Responsive Biological Pacing at Physiological Heart Rates
Gerard J. J. Boink, Lian Duan, Bruce D. Nearing, Iryna N. Shlapakova, Eugene A. Sosunov, Evgeny P. Anyukhovsky, Eugene Bobkov, Yelena Kryukova, Nazira Ozgen, Peter Danilo, Jr, Ira S. Cohen, Richard L. Verrier, Richard B. Robinson, Michael R. Rosen
J Am Coll Cardiol. Author manuscript; available in PMC 2017 Jun 29.
Published in final edited form as: J Am Coll Cardiol. 2013 Mar 19; 61(11): 1192–1201. Published online 2013 Feb 6. doi: 10.1016/j.jacc.2012.12.031
PMCID:
PMC5490253
AbstractArticlePDF–1.1M
7.
Identification of methylated genes in salivary gland adenoid cystic carcinoma xenografts using global demethylation and methylation microarray screening
SHIZHANG LING, ELENI M. RETTIG, MARIETTA TAN, XIAOFEI CHANG, ZHIMING WANG, MARIANA BRAIT, JUSTIN A. BISHOP, ELANA J. FERTIG, MICHAEL CONSIDINE, MICHAEL J. WICK, PATRICK K. HA
Int J Oncol. 2016 Jul; 49(1): 225–234. Published online 2016 May 18. doi: 10.3892/ijo.2016.3532
PMCID:
PMC4902070
AbstractArticlePDF–496K
8.
Autism-Associated SHANK3 Haploinsufficiency Causes Ih-Channelopathy in Human Neurons
Fei Yi, Tamas Danko, Salome Calado Botelho, Christopher Patzke, ChangHui Pak, Marius Wernig, Thomas C. Südhof
Science. Author manuscript; available in PMC 2016 Jun 10.
Published in final edited form as: Science. 2016 May 6; 352(6286): aaf2669. Published online 2016 Mar 10. doi: 10.1126/science.aaf2669
PMCID:
PMC4901875
AbstractArticlePDF–1.9M
9.
Molecular Mapping of Sinoatrial Node HCN Channel Expression in the Human Heart
Ning Li, Thomas A. Csepe, Brian J. Hansen, Halina Dobrzynski, Robert S.D. Higgins, Ahmet Kilic, Peter J. Mohler, Paul M.L. Janssen, Michael R. Rosen, Brandon J. Biesiadecki, Vadim V. Fedorov
Circ Arrhythm Electrophysiol. Author manuscript; available in PMC 2016 Oct 1.
Published in final edited form as: Circ Arrhythm Electrophysiol. 2015 Oct; 8(5): 1219–1227. Published online 2015 Aug 24. doi: 10.1161/CIRCEP.115.003070
PMCID:
PMC4618238
AbstractArticlePDF–2.1M
10.
Isoform dependent regulation of human HCN channels by cholesterol
Oliver Fürst, Nazzareno D’Avanzo
Sci Rep. 2015; 5: 14270. Published online 2015 Sep 25. doi: 10.1038/srep14270
PMCID:
PMC4585891
AbstractArticlePDF–1.5M
11.
Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation
YAO-DONG LI, YI-FAN HONG, YUEERGULI YUSUFUAJI, BAO-PENG TANG, XIAN-HUI ZHOU, GUO-JUN XU, JIN-XIN LI, LIN SUN, JIANG-HUA ZHANG, QIANG XIN, JIAN XIONG, YU-TONG JI, YU ZHANG
Mol Med Rep. 2015 Sep; 12(3): 3243–3248. Published online 2015 May 25. doi: 10.3892/mmr.2015.3831
PMCID:
PMC4526032
AbstractArticlePDF–587K
12.
Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function
Andrea Saponaro, Sofia R. Pauleta, Francesca Cantini, Manolis Matzapetakis, Christian Hammann, Chiara Donadoni, Lei Hu, Gerhard Thiel, Lucia Banci, Bina Santoro, Anna Moroni
Proc Natl Acad Sci U S A. 2014 Oct 7; 111(40): 14577–14582. Published online 2014 Sep 2. doi: 10.1073/pnas.1410389111
PMCID:
PMC4210022
AbstractArticlePDF–1.0M
13.
Novel HCN2 Mutation Contributes to Febrile Seizures by Shifting the Channel's Kinetics in a Temperature-Dependent Manner
Yuki Nakamura, Xiuyu Shi, Tomohiro Numata, Yasuo Mori, Ryuji Inoue, Christoph Lossin, Tallie Z. Baram, Shinichi Hirose
PLoS One. 2013; 8(12): e80376. Published online 2013 Dec 4. doi: 10.1371/journal.pone.0080376
PMCID:
PMC3851455
AbstractArticlePDF–703K
14.
Augmented Currents of an HCN2 Variant in Patients with Febrile Seizure Syndromes
Leanne M. Dibbens, Christopher A. Reid, Bree Hodgson, Evan A. Thomas, Alison M. Phillips, Elena Gazina, Brett A. Cromer, Alison L. Clarke, Tallie Z. Baram, Ingrid E. Scheffer, Samuel F. Berkovic, Steven Petrou
Ann Neurol. Author manuscript; available in PMC 2012 Jun 26.
Published in final edited form as: Ann Neurol. 2010 Apr; 67(4): 542–546. doi: 10.1002/ana.21909
PMCID:
PMC3383007
AbstractArticlePDF–510K
15.
Tetramerization Dynamics of C-terminal Domain Underlies Isoform-specific cAMP Gating in Hyperpolarization-activated Cyclic Nucleotide-gated Channels
Marco Lolicato, Marco Nardini, Sabrina Gazzarrini, Stefan Möller, Daniela Bertinetti, Friedrich W. Herberg, Martino Bolognesi, Holger Martin, Marina Fasolini, Jay A. Bertrand, Cristina Arrigoni, Gerhard Thiel, Anna Moroni
J Biol Chem. 2011 Dec 30; 286(52): 44811–44820. Published online 2011 Oct 17. doi: 10.1074/jbc.M111.297606
PMCID:
PMC3247997
AbstractArticlePDF–1.5M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
Enhanced Expression of a Specific Hyperpolarization-Activated Cyclic Nucleotide-Gated Cation Channel (HCN) in Surviving Dentate Gyrus Granule Cells of Human and Experimental Epileptic Hippocampus
Roland A. Bender, Sheila V. Soleymani, Amy L. Brewster, Snow T. Nguyen, Heinz Beck, Gary W. Mathern, Tallie Z. Baram
J Neurosci. 2003 Jul 30; 23(17): 6826–6836. doi: 10.1523/JNEUROSCI.23-17-06826.2003
PMCID:
PMC3100807
AbstractArticlePDF–637K
18.
Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study
Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators
Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452
PMCID:
PMC2945168
AbstractArticlePDF–153K
19.
Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip
Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani
Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014
PMCID:
PMC2775832
AbstractArticlePDF–2.8M
20.
Mutation analysis of the hyperpolarization-activated cyclic nucleotide-gated channels HCN1 and HCN2 in idiopathic generalized epilepsy
Bin Tang, Thomas Sander, Kimberley B. Craven, Anne Hempelmann, Andrew Escayg
Neurobiol Dis. Author manuscript; available in PMC 2009 Jul 13.
Published in final edited form as: Neurobiol Dis. 2008 Jan; 29(1): 59–70. Published online 2007 Aug 24. doi: 10.1016/j.nbd.2007.08.006
PMCID:
PMC2709210
AbstractArticlePDF–1.2M

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