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Select item 77806421.

UBXN2A regulates nicotinic receptor degradation by modulating the E3 ligase activity of CHIP

Yanfen Teng, Khosrow Rezvani, Mariella De Biasi

Biochem Pharmacol. Author manuscript; available in PMC 2021 Jan 4.

Published in final edited form as: Biochem Pharmacol. 2015 Oct 15; 97(4): 518–530. Published online 2015 Aug 8. doi: 10.1016/j.bcp.2015.08.084

PMCID:: PMC7780642

Abstract Article PDF–1.5M

Select item 69461842.

2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

Soojay Banerjee, Alberto Bartesaghi, Alan Merk, Prashant Rao, Stacie L. Bulfer, Yongzhao Yan, Neal Green, Barbara Mroczkowski, R. Jeffrey Neitz, Peter Wipf, Veronica Falconieri, Raymond J. Deshaies, Jacqueline L. S. Milne, Donna Huryn, Michelle Arkin, Sriram Subramaniam

Science. Author manuscript; available in PMC 2020 Jan 7.

Published in final edited form as: Science. 2016 Feb 19; 351(6275): 871–875. Published online 2016 Jan 28. doi: 10.1126/science.aad7974

PMCID:: PMC6946184

Abstract Article PDF–2.4M

Select item 55956733.

The valosin‐containing protein is a novel repressor of cardiomyocyte hypertrophy induced by pressure overload

Ning Zhou, Ben Ma, Shaunrick Stoll, Tristan T. Hays, Hongyu Qiu

Aging Cell. 2017 Oct; 16(5): 1168–1179. Published online 2017 Aug 11. doi: 10.1111/acel.12653

PMCID:: PMC5595673

Abstract Article PDF–1.9M

Select item 55922444.

Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5

Joshua E. Flack, Juliusz Mieszczanek, Nikola Novcic, Mariann Bienz

Mol Cell. 2017 Jul 20; 67(2): 181–193.e5. doi: 10.1016/j.molcel.2017.06.009

PMCID:: PMC5592244

Abstract Article

Select item 52423755.

VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy

Chrisovalantis Papadopoulos, Philipp Kirchner, Monika Bug, Daniel Grum, Lisa Koerver, Nina Schulze, Robert Poehler, Alina Dressler, Sven Fengler, Khalid Arhzaouy, Vanda Lux, Michael Ehrmann, Conrad C Weihl, Hemmo Meyer

EMBO J. 2017 Jan 17; 36(2): 135–150. Published online 2016 Oct 17. doi: 10.15252/embj.201695148

PMCID:: PMC5242375

Abstract Article PDF–10M

Select item 48027256.

Valosin-containing protein is a key mediator between autophagic cell death and apoptosis in adult hippocampal neural stem cells following insulin withdrawal

Bo Kyoung Yeo, Caroline Jeeyeon Hong, Kyung Min Chung, Hanwoong Woo, Kyungchan Kim, Seonghee Jung, Eun-Kyoung Kim, Seong-Woon Yu

Mol Brain. 2016; 9: 31. Published online 2016 Mar 22. doi: 10.1186/s13041-016-0212-8

PMCID:: PMC4802725

Abstract Article PDF–2.0M

Select item 47430007.

Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression

André Franz, Paul A. Pirson, Domenic Pilger, Swagata Halder, Divya Achuthankutty, Hamid Kashkar, Kristijan Ramadan, Thorsten Hoppe

Nat Commun. 2016; 7: 10612. Published online 2016 Feb 4. doi: 10.1038/ncomms10612

Correction in:: Nat Commun. 2016; 7: 11593.

PMCID:: PMC4743000

Abstract Article PDF–3.6M

Select item 46380458.

Interacting Network of the Gap Junction (GJ) Protein Connexin43 (Cx43) is Modulated by Ischemia and Reperfusion in the Heart

Tania Martins-Marques, Sandra Isabel Anjo, Paulo Pereira, Bruno Manadas, Henrique Girão

Mol Cell Proteomics. 2015 Nov; 14(11): 3040–3055. Published online 2015 Aug 27. doi: 10.1074/mcp.M115.052894

PMCID:: PMC4638045

Abstract Article PDF–2.5M

Select item 43867069.

Rare Manifestation of a c.290 C>T, p.Gly97Glu VCP Mutation

Nivedita U. Jerath, Cameron D. Crockett, Steven A. Moore, Michael E. Shy, Conrad C. Weihl, Tsui-Fen Chou, Tiffany Grider, Michael A. Gonzalez, Stephan Zuchner, Andrea Swenson

Case Rep Genet. 2015; 2015: 239167. Published online 2015 Mar 23. doi: 10.1155/2015/239167

PMCID:: PMC4386706

Abstract Article PDF–2.0M

Select item 420846210.

A novel mutation in VCP causes Charcot–Marie–Tooth Type 2 disease

Michael A. Gonzalez, Shawna M. Feely, Fiorella Speziani, Alleene V. Strickland, Matt Danzi, Chelsea Bacon, Youjin Lee, Tsui-Fen Chou, Susan H. Blanton, Conrad C. Weihl, Stephan Zuchner, Michael E. Shy

Brain. 2014 Nov; 137(11): 2897–2902. Published online 2014 Aug 14. doi: 10.1093/brain/awu224

PMCID:: PMC4208462

Abstract Article PDF–511K

Select item 415568911.

Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion

Sushant Bhatnagar, Mufaddal S. Soni, Lindsay S. Wrighton, Alexander S. Hebert, Amber S. Zhou, Pradyut K. Paul, Trillian Gregg, Mary E. Rabaglia, Mark P. Keller, Joshua J. Coon, Alan D. Attie

J Biol Chem. 2014 Sep 5; 289(36): 25276–25286. Published online 2014 Jul 7. doi: 10.1074/jbc.M114.575985

PMCID:: PMC4155689

Abstract Article PDF–1.1M

Select item 384311412.

Pathogenic VCP Mutations Induce Mitochondrial Uncoupling and Reduced ATP Levels

Fernando Bartolome, Hsiu-Chuan Wu, Victoria S. Burchell, Elisavet Preza, Selina Wray, Colin J. Mahoney, Nick C. Fox, Andrea Calvo, Antonio Canosa, Cristina Moglia, Jessica Mandrioli, Adriano Chiò, Richard W. Orrell, Henry Houlden, John Hardy, Andrey Y. Abramov, Helene Plun-Favreau

Neuron. 2013 Apr 10; 78(1): 57–64. doi: 10.1016/j.neuron.2013.02.028

PMCID:: PMC3843114

Abstract Article

Select item 382919113.

Caveolin-1 Interacts with Derlin-1 and Promotes Ubiquitination and Degradation of Cyclooxygenase-2 via Collaboration with p97 Complex

Shu-Fen Chen, Chun-Hu Wu, Yen-Ming Lee, Kabik Tam, Yi-Chen Tsai, Jun-Yang Liou, Song-Kun Shyue

J Biol Chem. 2013 Nov 15; 288(46): 33462–33469. Published online 2013 Oct 2. doi: 10.1074/jbc.M113.521799

PMCID:: PMC3829191

Abstract Article PDF–2.9M

Select item 381102214.

Isolation of Mammalian 26S Proteasomes and p97/VCP Complexes Using the Ubiquitin-like Domain from HHR23B Reveals Novel Proteasome-Associated Proteins

Henrike C. Besche, Wilhelm Haas, Steven P. Gygi, Alfred L. Goldberg

Biochemistry. Author manuscript; available in PMC 2013 Oct 29.

Published in final edited form as: Biochemistry. 2009 Mar 24; 48(11): 10.1021/bi802198q. doi: 10.1021/bi802198q

PMCID:: PMC3811022

Abstract Article PDF–3.7M

Select item 377350515.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561