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Select item 101573061.

The transcriptional regulator Sin3A balances IL‐17A and Foxp3 expression in primary CD4 T cells

Laura Perucho, Laura Icardi, Elisabetta Di Simone, Veronica Basso, Alessandra Agresti, Amaia Vilas Zornoza, Teresa Lozano, Felipe Prosper, Juan José Lasarte, Anna Mondino

EMBO Rep. 2023 May; 24(5): e55326. Published online 2023 Mar 16. doi: 10.15252/embr.202255326

PMCID:: PMC10157306

Abstract Article PDF–1.8M

Select item 99505222.

Telomeres cooperate in zygotic genome activation by affecting DUX4/Dux transcription

Xiaorui Zhang, Changquan Zhang, Di Zhou, Tianlei Zhang, Xueqin Chen, Jinlin Ren, Caixia He, Fei Meng, Qinwei Zhou, Qiaohui Yang, Congling Dai, Ge Lin, Sicong Zeng, Lizhi Leng

iScience. 2023 Mar 17; 26(3): 106158. Published online 2023 Feb 8. doi: 10.1016/j.isci.2023.106158

PMCID:: PMC9950522

Abstract Article PDF–3.7M

Select item 96300893.

An Overfeeding-Induced Obesity Mouse Model Reveals Necessity for Sin3a in Postnatal Peak β-Cell Mass Acquisition

Alberto Bartolomé, Yann Ravussin, Junjie Yu, Anthony W. Ferrante, Jr., Utpal B. Pajvani

Diabetes. 2022 Nov; 71(11): 2395–2401. Published online 2022 Aug 9. doi: 10.2337/db22-0306

PMCID:: PMC9630089

Abstract Article PDF–61M

Select item 83132394.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 82249325.

The Neuronal Transcription Factor Myt1L Interacts via a Conserved Motif with the PAH1 domain of Sin3 to Recruit the Sin3L/Rpd3L Histone Deacetylase Complex

Ryan Dale Marcum, Ishwar Radhakrishnan

FEBS Lett. Author manuscript; available in PMC 2021 Jun 24.

Published in final edited form as: FEBS Lett. 2020 Jul; 594(14): 2322–2330. Published online 2020 May 23. doi: 10.1002/1873-3468.13811

PMCID:: PMC8224932

Abstract Article PDF–1.6M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 72432927.

Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca²⁺ Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response

Xiaodun Yang, Sarah M. Graff, Cody N. Heiser, Kung-Hsien Ho, Bob Chen, Alan J. Simmons, Austin N. Southard-Smith, Gregory David, David A. Jacobson, Irina Kaverina, Christopher V.E. Wright, Ken S. Lau, Guoqiang Gu

Diabetes. 2020 Jun; 69(6): 1219–1231. Published online 2020 Apr 3. doi: 10.2337/db19-0721

PMCID:: PMC7243292

Abstract Article PDF–2.7M

Select item 71414068.

Transcriptional corepressor SIN3A regulates hippocampal synaptic plasticity via Homer1/mGluR5 signaling

Morgan Bridi, Hannah Schoch, Cédrick Florian, Shane G. Poplawski, Anamika Banerjee, Joshua D. Hawk, Giulia S. Porcari, Camille Lejards, Chang-Gyu Hahn, Karl-Peter Giese, Robbert Havekes, Nelson Spruston, Ted Abel

JCI Insight. 2020 Mar 12; 5(5): e92385. Published online 2020 Mar 12. doi: 10.1172/jci.insight.92385

PMCID:: PMC7141406

Abstract Article PDF–5.7M

Select item 69942479.

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells

Samudyata, Paulo P. Amaral, Pär G. Engström, Samuel C. Robson, Michael L. Nielsen, Tony Kouzarides, Gonçalo Castelo-Branco

Exp Cell Res. Author manuscript; available in PMC 2020 Aug 1.

Published in final edited form as: Exp Cell Res. 2019 Aug 1; 381(1): 129–138. Published online 2019 May 9. doi: 10.1016/j.yexcr.2019.05.006

PMCID:: PMC6994247

Abstract Article PDF–1.6M

Select item 690273010.

Sin3a regulates the developmental progression through morula-to-blastocyst transition via Hdac1

Panpan Zhao, Shuang Li, Huanan Wang, Yanna Dang, Lefeng Wang, Tong Liu, Shaohua Wang, Xinhong Li, Kun Zhang

FASEB J. 2019 Nov; 33(11): 12541–12553. Published online 2019 Aug 26. doi: 10.1096/fj.201901213R

PMCID:: PMC6902730

Abstract Article

Select item 629804011.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 623163812.

Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each

Afzal M. Dogar, Ramona Pauchard-Batschulat, Barbara Grisoni-Neupert, Larry Richman, Alexandra Paillusson, Sylvain Pradervand, Otto Hagenbüchle, Giovanna Ambrosini, Christoph D. Schmid, Philipp Bucher, Lukas C. Kühn

PLoS One. 2018; 13(11): e0206823. Published online 2018 Nov 12. doi: 10.1371/journal.pone.0206823

PMCID:: PMC6231638

Abstract Article PDF–3.8M

Select item 619715413.

microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function

Fanny Langlet, Marcel Tarbier, Rebecca A. Haeusler, Stefania Camastra, Eleuterio Ferrannini, Marc R. Friedländer, Domenico Accili

Mol Metab. 2018 Nov; 17: 49–60. Published online 2018 Aug 11. doi: 10.1016/j.molmet.2018.08.003

PMCID:: PMC6197154

Abstract Article PDF–2.3M

Select item 615860814.

Sin3a–Tet1 interaction activates gene transcription and is required for embryonic stem cell pluripotency

Fugui Zhu, Qianshu Zhu, Dan Ye, Qingquan Zhang, Yiwei Yang, Xudong Guo, Zhenping Liu, Zeyidan Jiapaer, Xiaoping Wan, Guiying Wang, Wen Chen, Songcheng Zhu, Cizhong Jiang, Weiyang Shi, Jiuhong Kang

Nucleic Acids Res. 2018 Jul 6; 46(12): 6026–6040. Published online 2018 May 4. doi: 10.1093/nar/gky347

PMCID:: PMC6158608

Abstract Article PDF–14M

Select item 611389015.

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1

Gina E. Elsen, Francesco Bedogni, Rebecca D. Hodge, Theo K. Bammler, James W. MacDonald, Susan Lindtner, John L. R. Rubenstein, Robert F. Hevner

Front Neurosci. 2018; 12: 571. Published online 2018 Aug 22. doi: 10.3389/fnins.2018.00571

PMCID:: PMC6113890

Abstract Article PDF–4.8M

Select item 607244116.

Loss of Fam60a, a Sin3a subunit, results in embryonic lethality and is associated with aberrant methylation at a subset of gene promoters

Ryo Nabeshima, Osamu Nishimura, Takako Maeda, Natsumi Shimizu, Takahiro Ide, Kenta Yashiro, Yasuo Sakai, Chikara Meno, Mitsutaka Kadota, Hidetaka Shiratori, Shigehiro Kuraku, Hiroshi Hamada

eLife. 2018; 7: e36435. Published online 2018 Aug 2. doi: 10.7554/eLife.36435

PMCID:: PMC6072441

Abstract Article PDF–5.6M

Select item 568784917.

Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling

Fanny Langlet, Rebecca A. Haeusler, Daniel Lindén, Elke Ericson, Tyrrell Norris, Anders Johansson, Joshua R. Cook, Kumiko Aizawa, Ling Wang, Christoph Buettner, Domenico Accili

Cell. Author manuscript; available in PMC 2018 Nov 2.

Published in final edited form as: Cell. 2017 Nov 2; 171(4): 824–835.e18. Published online 2017 Oct 19. doi: 10.1016/j.cell.2017.09.045

PMCID:: PMC5687849

Abstract Article PDF–2.5M

Select item 553876918.

Fam60a defines a variant Sin3a‐Hdac complex in embryonic stem cells required for self‐renewal

Gundula Streubel, Darren J Fitzpatrick, Giorgio Oliviero, Andrea Scelfo, Bruce Moran, Sudipto Das, Nayla Munawar, Ariane Watson, Kieran Wynne, Gian Luca Negri, Eugene T Dillon, SriGanesh Jammula, Karsten Hokamp, Darran P O'Connor, Diego Pasini, Gerard Cagney, Adrian P Bracken

EMBO J. 2017 Aug 1; 36(15): 2216–2232. Published online 2017 May 29. doi: 10.15252/embj.201696307

PMCID:: PMC5538769

Abstract Article PDF–1.1M

Select item 553692919.

Sin3a regulates epithelial progenitor cell fate during lung development

Changfu Yao, Gianni Carraro, Bindu Konda, Xiangrong Guan, Takako Mizuno, Norika Chiba, Matthew Kostelny, Adrianne Kurkciyan, Gregory David, Jonathan L. McQualter, Barry R. Stripp

Development. 2017 Jul 15; 144(14): 2618–2628. doi: 10.1242/dev.149708

PMCID:: PMC5536929

Abstract Article

Select item 532812220.

The Sin3a/HDAC corepressor complex functionally cooperates with Nanog to promote pluripotency

Arven Saunders, Xin Huang, Miguel Fidalgo, Michael H. Reimer, Jr, Francesco Faiola, Junjun Ding, Carlos Sánchez-Priego, Diana Guallar, Carmen Sáenz, Dan Li, Jianlong Wang

Cell Rep. Author manuscript; available in PMC 2017 Feb 27.

Published in final edited form as: Cell Rep. 2017 Feb 14; 18(7): 1713–1726. doi: 10.1016/j.celrep.2017.01.055

PMCID:: PMC5328122

Abstract Article PDF–2.5M

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