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Items: 1 to 20 of 52

1.
Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis
Chao Lu, Pengyun Qiao, Ruihai Fu, Yadi Wang, Jiayi Lu, Xi Ling, Lu Liu, Yujun Sun, Chune Ren, Zhenhai Yu
Cell Death Dis. 2022 Sep; 13(9): 790. Published online 2022 Sep 15. doi: 10.1038/s41419-022-05241-6
Correction in:
Cell Death Dis. 2024 Jul; 15(7): 469.
PMCID:
PMC9477845
AbstractArticlePDF–12M
2.
HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis
Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai
Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4
PMCID:
PMC9338313
AbstractArticlePDF–2.8M
3.
Stabilization of PIM Kinases in Hypoxia Is Mediated by the Deubiquitinase USP28
Rachel K. Toth, Regina Solomon, Noel A. Warfel
Cells. 2022 Mar; 11(6): 1006. Published online 2022 Mar 16. doi: 10.3390/cells11061006
PMCID:
PMC8947361
AbstractArticlePDF–2.4M
4.
Turnover of the mTOR inhibitor, DEPTOR, and downstream AKT phosphorylation in multiple myeloma cells, is dependent on ERK1-mediated phosphorylation
Mario Vega, Yu Chen, Yijiang Shi, Joseph Gera, Alan Lichtenstein
J Biol Chem. 2022 Apr; 298(4): 101750. Published online 2022 Feb 23. doi: 10.1016/j.jbc.2022.101750
PMCID:
PMC8933699
AbstractArticlePDF–1.6M
5.
Long non-coding RNA SOX21-AS1 modulates lung cancer progress upon microRNA miR-24-3p/PIM2 axis
Fengfeng Wang, Tengfei Gu, Yao Chen, Yu Chen, Dan Xiong, Yehan Zhu
Bioengineered. 2021; 12(1): 6724–6737. Published online 2021 Sep 13. doi: 10.1080/21655979.2021.1955578
PMCID:
PMC8806559
AbstractArticlePDF–4.0M
6.
Positive regulation of PFKFB3 by PIM2 promotes glycolysis and paclitaxel resistance in breast cancer
Chao Lu, Pengyun Qiao, Yonghong Sun, Chune Ren, Zhenhai Yu
Clin Transl Med. 2021 Apr; 11(4): e400. Published online 2021 May 1. doi: 10.1002/ctm2.400
PMCID:
PMC8087946
AbstractArticlePDF–9.7M
7.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
8.
Fructose-1, 6-bisphosphatase 1 interacts with NF-κB p65 to regulate breast tumorigenesis via PIM2 induced phosphorylation
Chao Lu, Chune Ren, Tingting Yang, Yonghong Sun, Pengyun Qiao, Xue Han, Zhenhai Yu
Theranostics. 2020; 10(19): 8606–8618. Published online 2020 Jul 9. doi: 10.7150/thno.46861
PMCID:
PMC7392005
AbstractArticlePDF–2.7M
9.
PIM2 promotes hepatocellular carcinoma tumorigenesis and progression through activating NF-κB signaling pathway
Xuming Tang, Tingting Cao, Yun Zhu, Liyi Zhang, Jinna Chen, Tengfei Liu, Xiaoyan Ming, Shuo Fang, Yun-fei Yuan, Lingxi Jiang, Jian-Dong Huang, Xin-Yuan Guan
Cell Death Dis. 2020 Jul; 11(7): 510. Published online 2020 Jul 2. doi: 10.1038/s41419-020-2700-0
PMCID:
PMC7343807
AbstractArticlePDF–5.6M
10.
Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection
Wai Fook Leong, Vincent T. K. Chow
Cell Microbiol. 2006 Apr; 8(4): 565–580. Published online 2005 Nov 8. doi: 10.1111/j.1462-5822.2005.00644.x
PMCID:
PMC7162300
AbstractArticlePDF–345K
11.
Inhibition of PIM2 in liver cancer decreases tumor cell proliferation in vitro and in vivo primarily through the modulation of cell cycle progression
Pia Kronschnabl, Arnold Grünweller, Roland K. Hartmann, Achim Aigner, Ulrike Weirauch
Int J Oncol. 2020 Feb; 56(2): 448–459. Published online 2019 Dec 10. doi: 10.3892/ijo.2019.4936
PMCID:
PMC6959465
AbstractArticlePDF–1.4M
12.
TRAF3 regulates the oncogenic proteins Pim2 and c-Myc to restrain survival in normal and malignant B cells
Amy L. Whillock, Nurbek Mambetsariev, Wai W. Lin, Laura L. Stunz, Gail A. Bishop
Sci Rep. 2019; 9: 12884. Published online 2019 Sep 9. doi: 10.1038/s41598-019-49390-9
Correction in:
Sci Rep. 2019; 9: 17502.
PMCID:
PMC6733949
AbstractArticlePDF–2.1M
13.
PIM2-mediated phosphorylation of hexokinase 2 is critical for tumor growth and paclitaxel resistance in breast cancer
Tingting Yang, Chune Ren, Pengyun Qiao, Xue Han, Li Wang, Shijun Lv, Yonghong Sun, Zhijun Liu, Yu Du, Zhenhai Yu
Oncogene. 2018; 37(45): 5997–6009. Published online 2018 Jul 9. doi: 10.1038/s41388-018-0386-x
Correction in:
Oncogene. 2020; 39(3): 720–721.
PMCID:
PMC6224402
AbstractArticlePDF–3.6M
14.
CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia
Qing-Yun Wu, Yuan-Yuan Zhu, Yang Liu, Fang Wei, Yu-Xue Tong, Jiang Cao, Ping Zhou, Ming-Shan Niu, Zhen-Yu Li, Ling-Yu Zeng, Feng Li, Kai-Lin Xu
Cell Death Dis. 2018 Jul; 9(7): 774. Published online 2018 Jul 10. doi: 10.1038/s41419-018-0812-6
PMCID:
PMC6039501
AbstractArticlePDF–2.7M
15.
Microenvironment‐induced PIM kinases promote CXCR4‐triggered mTOR pathway required for chronic lymphocytic leukaemia cell migration
Emilia Białopiotrowicz, Patryk Górniak, Monika Noyszewska‐Kania, Bartosz Puła, Hanna Makuch‐Łasica, Grażyna Nowak, Aleksandra Bluszcz, Maciej Szydłowski, Ewa Jabłonska, Karolina Piechna, Tomasz Sewastianik, Anna Polak, Ewa Lech‐Marańda, Bożena K. Budziszewska, Maja Wasylecka‐Juszczyńska, Katarzyna Borg, Krzysztof Warzocha, Wojciech Czardybon, Michał Gałęzowski, Renata Windak, Krzysztof Brzózka, Przemysław Juszczyński
J Cell Mol Med. 2018 Jul; 22(7): 3548–3559. Published online 2018 Apr 17. doi: 10.1111/jcmm.13632
PMCID:
PMC6010703
AbstractArticlePDF–1.4M
16.
Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins
James E. Tomkins, Sybille Dihanich, Alexandra Beilina, Raffaele Ferrari, Nicolò Ilacqua, Mark R. Cookson, Patrick A. Lewis, Claudia Manzoni
Proteomics. 2018 May; 18(10): 1700444. Published online 2018 Apr 17. doi: 10.1002/pmic.201700444
PMCID:
PMC5992104
AbstractArticlePDF–1.2M
17.
PIM2 interacts with tristetraprolin and promotes breast cancer tumorigenesis
Chune Ren, Tingting Yang, Pengyun Qiao, Li Wang, Xue Han, Shijun Lv, Yonghong Sun, Zhijun Liu, Yu Du, Zhenhai Yu
Mol Oncol. 2018 May; 12(5): 690–704. Published online 2018 Apr 14. doi: 10.1002/1878-0261.12192
PMCID:
PMC5928357
AbstractArticlePDF–1.3M
18.
Role of PIM2 in allergic asthma
Wei Du, Tiantian Chen, Yingmeng Ni, Xiaoxia Hou, Youchao Yu, Qi Zhou, Fang Wu, Wei Tang, Guochao Shi
Mol Med Rep. 2017 Nov; 16(5): 7504–7512. Published online 2017 Sep 18. doi: 10.3892/mmr.2017.7499
PMCID:
PMC5865883
AbstractArticlePDF–1.3M
19.
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions
Kyuho Han, Edwin E. Jeng, Gaelen T. Hess, David W. Morgens, Amy Li, Michael C. Bassik
Nat Biotechnol. Author manuscript; available in PMC 2017 Sep 20.
Published in final edited form as: Nat Biotechnol. 2017 May; 35(5): 463–474. Published online 2017 Mar 20. doi: 10.1038/nbt.3834
PMCID:
PMC5557292
AbstractArticlePDF–3.4M
20.
PIM kinases as therapeutic targets against advanced melanoma
Batool Shannan, Andrea Watters, Quan Chen, Stefan Mollin, Markus Dörr, Eric Meggers, Xiaowei Xu, Phyllis A. Gimotty, Michela Perego, Ling Li, Joseph Benci, Clemens Krepler, Patricia Brafford, Jie Zhang, Zhi Wei, Gao Zhang, Qin Liu, Xiangfan Yin, Katherine L. Nathanson, Meenhard Herlyn, Adina Vultur
Oncotarget. 2016 Aug 23; 7(34): 54897–54912. Published online 2016 Jul 19. doi: 10.18632/oncotarget.10703
PMCID:
PMC5342389
AbstractArticlePDF–8.2M

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