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Items: 1 to 20 of 22

1.
Bromodomain protein BRDT directs ΔNp63 function and super-enhancer activity in a subset of esophageal squamous cell carcinomas
Xin Wang, Ana P. Kutschat, Moyuru Yamada, Evangelos Prokakis, Patricia Böttcher, Koji Tanaka, Yuichiro Doki, Feda H. Hamdan, Steven A. Johnsen
Cell Death Differ. 2021 Jul; 28(7): 2207–2220. Published online 2021 Mar 3. doi: 10.1038/s41418-021-00751-w
PMCID:
PMC8257622
AbstractArticlePDF–3.7M
2.
Discovery and characterization of bromodomain 2–specific inhibitors of BRDT
Zhifeng Yu, Angela F. Ku, Justin L. Anglin, Rajesh Sharma, Melek Nihan Ucisik, John C. Faver, Feng Li, Pranavanand Nyshadham, Nicholas Simmons, Kiran L. Sharma, Sureshbabu Nagarajan, Kevin Riehle, Gundeep Kaur, Banumathi Sankaran, Marta Storl-Desmond, Stephen S. Palmer, Damian W. Young, Choel Kim, Martin M. Matzuk
Proc Natl Acad Sci U S A. 2021 Mar 2; 118(9): e2021102118. Published online 2021 Feb 26. doi: 10.1073/pnas.2021102118
PMCID:
PMC7936271
AbstractArticlePDF–2.3M
3.
BRDT is a novel regulator of eIF4EBP1 in renal cell carcinoma
Pei Wan, Zhilin Chen, Weifeng Zhong, Huiming Jiang, Zhicheng Huang, Dong Peng, Qiang He, Nanhui Chen
Oncol Rep. 2020 Dec; 44(6): 2475–2486. Published online 2020 Oct 8. doi: 10.3892/or.2020.7796
PMCID:
PMC7610328
AbstractArticlePDF–982K
4.
Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity
Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller
Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119
PMCID:
PMC6942044
AbstractArticlePDF–10M
5.
Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development
Pu Wang, Feng Yan, Zhijun Li, Yanbao Yu, Scott E. Parnell, Yue Xiong
J Clin Invest. 2019 Oct 1; 129(10): 4393–4407. Published online 2019 Sep 9. doi: 10.1172/JCI129107
PMCID:
PMC6763242
AbstractArticlePDF–12M
6.
Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains
Jean-Philippe Lambert, Sarah Picaud, Takao Fujisawa, Huayun Hou, Pavel Savitsky, Liis Uusküla-Reimand, Gagan D. Gupta, Hala Abdouni, Zhen-Yuan Lin, Monika Tucholska, James D.R. Knight, Beatriz Gonzalez-Badillo, Nicole St-Denis, Joseph A. Newman, Manuel Stucki, Laurence Pelletier, Nuno Bandeira, Michael D. Wilson, Panagis Filippakopoulos, Anne-Claude Gingras
Mol Cell. 2019 Feb 7; 73(3): 621–638.e17. doi: 10.1016/j.molcel.2018.11.006
PMCID:
PMC6375729
AbstractArticlePDF–10M
7.
FBP1 loss contributes to BET inhibitors resistance by undermining c-Myc expression in pancreatic ductal adenocarcinoma
Bo Wang, Ping Fan, Jingyuan Zhao, Heyu Wu, Xin Jin, Heshui Wu
J Exp Clin Cancer Res. 2018; 37: 224. Published online 2018 Sep 10. doi: 10.1186/s13046-018-0888-y
PMCID:
PMC6131902
AbstractArticlePDF–5.7M
8.
Metabolically-derived lysine acylations and neighboring modifications tune BET bromodomain binding to histone H4
Michael D. Olp, Nan Zhu, Brian C. Smith
Biochemistry. Author manuscript; available in PMC 2018 Oct 17.
Published in final edited form as: Biochemistry. 2017 Oct 17; 56(41): 5485–5495. Published online 2017 Oct 5. doi: 10.1021/acs.biochem.7b00595
PMCID:
PMC5970795
AbstractArticlePDF–1.0M
9.
Whole-exome sequencing identified a homozygous BRDT mutation in a patient with acephalic spermatozoa
Lin Li, Yanwei Sha, Xi Wang, Ping Li, Jing Wang, Kehkooi Kee, Binbin Wang
Oncotarget. 2017 Mar 21; 8(12): 19914–19922. Published online 2017 Feb 10. doi: 10.18632/oncotarget.15251
PMCID:
PMC5386733
AbstractArticlePDF–2.3M
10.
The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis
Giorgio Oliviero, Nayla Munawar, Ariane Watson, Gundula Streubel, Gwendolyn Manning, Vivian Bardwell, Adrian P. Bracken, Gerard Cagney
Sci Rep. 2015; 5: 18388. Published online 2015 Dec 21. doi: 10.1038/srep18388
PMCID:
PMC4685312
AbstractArticlePDF–1.5M
11.
Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage
Romain Drissi, Marie-Line Dubois, Mélanie Douziech, François-Michel Boisvert
Mol Cell Proteomics. 2015 Jul; 14(7): 2002–2013. Published online 2015 May 11. doi: 10.1074/mcp.M115.048991
PMCID:
PMC4587322
AbstractArticlePDF–3.0M
12.
Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination
Fade Gong, Li-Ya Chiu, Ben Cox, François Aymard, Thomas Clouaire, Justin W. Leung, Michael Cammarata, Mercedes Perez, Poonam Agarwal, Jennifer S. Brodbelt, Gaëlle Legube, Kyle M. Miller
Genes Dev. 2015 Jan 15; 29(2): 197–211. doi: 10.1101/gad.252189.114
PMCID:
PMC4298138
AbstractArticlePDF–2.5M
13.
E2F6 Associates with BRG1 in Transcriptional Regulation
Janet Y. Leung, Joseph R. Nevins
PLoS One. 2012; 7(10): e47967. Published online 2012 Oct 17. doi: 10.1371/journal.pone.0047967
PMCID:
PMC3474740
AbstractArticlePDF–647K
14.
Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family
Panagis Filippakopoulos, Sarah Picaud, Maria Mangos, Tracy Keates, Jean-Philippe Lambert, Dalia Barsyte-Lovejoy, Ildiko Felletar, Rudolf Volkmer, Susanne Müller, Tony Pawson, Anne-Claude Gingras, Cheryl H. Arrowsmith, Stefan Knapp
Cell. 2012 Mar 30; 149(1): 214–231. doi: 10.1016/j.cell.2012.02.013
PMCID:
PMC3326523
AbstractArticlePDF–2.8M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M
17.
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
Dwayne A. Bisgrove, Tokameh Mahmoudi, Peter Henklein, Eric Verdin
Proc Natl Acad Sci U S A. 2007 Aug 21; 104(34): 13690–13695. Published online 2007 Aug 9. doi: 10.1073/pnas.0705053104
PMCID:
PMC1959443
AbstractArticlePDF–460K
18.
Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano
Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406
PMCID:
PMC1356129
AbstractArticlePDF–438K
19.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
20.
DNA Cloning Using In Vitro Site-Specific Recombination
James L. Hartley, Gary F. Temple, Michael A. Brasch
Genome Res. 2000 Nov; 10(11): 1788–1795. doi: 10.1101/gr.143000
PMCID:
PMC310948
AbstractArticlePDF–1.7M

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