U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 104

1.
MiR-106a-5p targets PFKFB3 and improves sepsis through regulating macrophage pyroptosis and inflammatory response
Yixin Chen, Ping Zhang, Fangwei Han, Yanying Zhou, Juexian Wei, Cailing Wang, Mingchuan Song, Shaopeng Lin, Yiming Xu, Xiaohui Chen
J Biol Chem. 2024 Jun; 300(6): 107334. Published online 2024 May 3. doi: 10.1016/j.jbc.2024.107334
PMCID:
PMC11190718
AbstractArticlePDF–6.2M
2.
Multi-omics and immunogenomics analysis revealed PFKFB3 as a targetable hallmark and mediates sunitinib resistance in papillary renal cell carcinoma: in silico study with laboratory verification
Zhongwen Lu, Yongsheng Pan, Songbo Wang, Jiajin Wu, Chenkui Miao, Zengjun Wang
Eur J Med Res. 2024; 29: 236. Published online 2024 Apr 15. doi: 10.1186/s40001-024-01808-5
PMCID:
PMC11017615
AbstractArticlePDF–12M
3.
Glycolytic enzyme PFKFB3 regulates sphingosine 1-phosphate receptor 1 in proangiogenic glomerular endothelial cells under diabetic condition
Baixue Yu, Kaiyuan Shen, Tingting Li, Jiawei Li, Mei Meng, Wenjie Liu, Qunye Tang, Tongyu Zhu, Xin Wang, Susan W. S. Leung, Yi Shi
Am J Physiol Cell Physiol. 2023 Nov 1; 325(5): C1354–C1368. Published online 2023 Oct 2. doi: 10.1152/ajpcell.00261.2023
PMCID:
PMC10861147
AbstractArticle
4.
Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis
Xin Tracy Liu, Yu Huang, Da Liu, Yingxin Celia Jiang, Min Zhao, Long Hoa Chung, Xingxing Daisy Han, Yinan Zhao, Jinbiao Chen, Paul Coleman, Ka Ka Ting, Collin Tran, Yingying Su, Claude Vincent Dennis, Atul Bhatnagar, Ken Liu, Anthony Simon Don, Mathew Alexander Vadas, Mark Douglas Gorrell, Shubiao Zhang, Michael Murray, Mary Meltem Kavurma, Geoffrey William McCaughan, Jennifer Ruth Gamble, Yanfei Qi
J Transl Med. 2024; 22: 43. Published online 2024 Jan 10. doi: 10.1186/s12967-023-04830-z
PMCID:
PMC10782643
AbstractArticlePDF–7.3M
5.
Glycolytic regulatory enzyme PFKFB3 as a prognostic and tumor microenvironment biomarker in human cancers
Qingen Da, Lei Huang, Can Huang, Zee Chen, Zhitong Jiang, Fang Huang, Tao Shen, Lu Sun, Zilong Yan, Xiaoqiang Ye, Jing Yi, Yu Huang, JingJing Da, Mingming Ren, Jikui Liu, Tao Wang, Zhen Han, Kunfu Ouyang
Aging (Albany NY) 2023 May 31; 15(10): 4533–4559. Published online 2023 May 30. doi: 10.18632/aging.204758
PMCID:
PMC10258027
AbstractArticlePDF–8.3M
6.
Deubiquitinase USP33 promotes the glycolysis and growth of osteosarcoma by modifying PFKFB3 ubiquitination and degradation
Bin Zhou, Nanye Wang, Qirui Chen, Juntao Ren, Xiaoling Fu, Xigao Cheng
Am J Cancer Res. 2023; 13(3): 922–935. Published online 2023 Mar 15.
PMCID:
PMC10077048
AbstractArticlePDF–2.6M
7.
Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation
Xiao Cheng, Xiupeng Jia, Chunnian Wang, Shangyan Zhou, Jiayi Chen, Lei Chen, Jinping Chen
World J Surg Oncol. 2023; 21: 112. Published online 2023 Mar 28. doi: 10.1186/s12957-023-02990-2
PMCID:
PMC10044395
AbstractArticlePDF–2.6M
8.
PFKFB3 overexpression in monocytes of patients with colon but not rectal cancer programs pro-tumor macrophages and is indicative for higher risk of tumor relapse
Irina Larionova, Marina Patysheva, Pavel Iamshchikov, Elena Kazakova, Anna Kazakova, Militsa Rakina, Evgeniya Grigoryeva, Anna Tarasova, Sergei Afanasiev, Natalia Bezgodova, Artem Kiselev, Alexey Dobrodeev, Dmitriy Kostromitskiy, Nadezhda Cherdyntseva, Julia Kzhyshkowska
Front Immunol. 2022; 13: 1080501. Published online 2023 Jan 17. doi: 10.3389/fimmu.2022.1080501
PMCID:
PMC9887047
AbstractArticlePDF–10M
9.
A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets
Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu
Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.
Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0
PMCID:
PMC9851973
AbstractArticlePDF–4.0M
10.
KLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells
Xinhua Zhang, Bin Zheng, Lingdan Zhao, Jiayi Shen, Zhan Yang, Yu Zhang, Ruirui Fan, Manli Zhang, Dong Ma, Lemin Zheng, Mingming Zhao, Huirong Liu, Jinkun Wen
Commun Biol. 2022; 5: 1332. Published online 2022 Dec 5. doi: 10.1038/s42003-022-04302-y
PMCID:
PMC9722670
AbstractArticlePDF–4.4M
11.
Increased stromal PFKFB3-mediated glycolysis in inflammatory bowel disease contributes to intestinal inflammation
Zhou Zhou, Leonie G. Plug, Thiago A. Patente, Eveline S. M. de Jonge-Muller, Amir Abou Elmagd, Andrea E. van der Meulen-de Jong, Bart Everts, Marieke C. Barnhoorn, Lukas J. A. C. Hawinkels
Front Immunol. 2022; 13: 966067. Published online 2022 Nov 2. doi: 10.3389/fimmu.2022.966067
PMCID:
PMC9670190
AbstractArticlePDF–16M
12.
SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis
Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han
Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6
PMCID:
PMC9523645
AbstractArticlePDF–3.9M
13.
PFKFB3 works on the FAK-STAT3-SOX2 axis to regulate the stemness in MPM
Sayantani Sarkar Bhattacharya, Prabhu Thirusangu, Ling Jin, Julie Staub, Viji Shridhar, Julian R. Molina
Br J Cancer. 2022 Oct 19; 127(7): 1352–1364. Published online 2022 Jul 6. doi: 10.1038/s41416-022-01867-7
PMCID:
PMC9519537
AbstractArticlePDF–4.8M
14.
PFKFB4 interacts with FBXO28 to promote HIF-1α signaling in glioblastoma
Emma Phillips, Jörg Balss, Frederic Bethke, Stefan Pusch, Stefan Christen, Thomas Hielscher, Martina Schnölzer, Michael N. C. Fletcher, Antje Habel, Claudia Tessmer, Lisa-Marie Brenner, Mona Göttmann, David Capper, Christel Herold-Mende, Andreas von Deimling, Sarah-Maria Fendt, Violaine Goidts
Oncogenesis. 2022 Dec; 11(1): 57. Published online 2022 Sep 17. doi: 10.1038/s41389-022-00433-3
PMCID:
PMC9482633
AbstractArticlePDF–3.4M
15.
PFKFB3 regulates cancer stemness through the hippo pathway in small cell lung carcinoma
Prabhu Thirusangu, Upasana Ray, Sayantani Sarkar Bhattacharya, Derek B. Oien, Ling Jin, Julie Staub, Nagarajan Kannan, Julian R. Molina, Viji Shridhar
Oncogene. 2022; 41(33): 4003–4017. Published online 2022 Jul 8. doi: 10.1038/s41388-022-02391-x
Correction in:
Oncogene. 2023; 42(1): 79–82.
PMCID:
PMC9374593
AbstractArticlePDF–8.1M
16.
Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner
Lucía García-Gutiérrez, Emma Fallahi, Nourhan Aboud, Niall Quinn, David Matallanas
Cell Death Dis. 2022 Aug; 13(8): 692. Published online 2022 Aug 8. doi: 10.1038/s41419-022-05147-3
PMCID:
PMC9360443
AbstractArticlePDF–5.8M
17.
Glycometabolic reprogramming-mediated proangiogenic phenotype enhancement of cancer-associated fibroblasts in oral squamous cell carcinoma: role of PGC-1α/PFKFB3 axis
Xiang Li, Erhui Jiang, Hui Zhao, Yang Chen, Yuming Xu, Chunyu Feng, Ji Li, Zhengjun Shang
Br J Cancer. 2022 Aug 1; 127(3): 449–461. Published online 2022 Apr 20. doi: 10.1038/s41416-022-01818-2
PMCID:
PMC9345921
AbstractArticlePDF–8.8M
18.
PFKFB3-mediated glycometabolism reprogramming modulates endothelial differentiation and angiogenic capacity of placenta-derived mesenchymal stem cells
Yang Zhang, Yanqi Zhong, Weifang Liu, Fanghui Zheng, Yin Zhao, Li Zou, Xiaoxia Liu
Stem Cell Res Ther. 2022; 13: 391. Published online 2022 Aug 2. doi: 10.1186/s13287-022-03089-3
PMCID:
PMC9344722
AbstractArticlePDF–6.1M
19.
Hyperglycemia induces miR-26-5p down-regulation to overexpress PFKFB3 and accelerate epithelial–mesenchymal transition in gastric cancer
Xiaobo He, Xiao Cheng, Jianfeng Ding, Maoming Xiong, Bo Chen, Guodong Cao
Bioengineered. 2022; 13(2): 2902–2917. Published online 2022 Jan 30. doi: 10.1080/21655979.2022.2026730
PMCID:
PMC8974024
AbstractArticlePDF–4.6M
20.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

You are here: NCBI > Literature > PubMed Central (PMC)
Support Center