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Select item 110950801.

MHC class II antigen presentation by tumoral lymphatics is required for tumor specific signature and suppressive functions of Tregs

Anastasia O. Gkountidi, Laure Garnier, Juan Dubrot, Julien Angelillo, Guillaume Harlé, Dale Brighouse, Ludovic J. Wrobel, Robert Pick, Christoph Scheiermann, Melody A. Swartz, Stéphanie Hugues

Cancer Immunol Res. Author manuscript; available in PMC 2024 May 15.

Published in final edited form as: Cancer Immunol Res. 2021 Jul; 9(7): 748–764. Published online 2021 May 5. doi: 10.1158/2326-6066.CIR-20-0784

PMCID:: PMC11095080

Abstract Article PDF–3.0M

Select item 110250162.

Bone marrow plasma cells require P2rX4 to sense extracellular ATP

Masaki Ishikawa, Zainul S. Hasanali, Yongge Zhao, Arundhoti Das, Marieke Lavaert, Carly J. Roman, Jennifer Londregan, David Allman, Avinash Bhandoola

Nature. Author manuscript; available in PMC 2024 Apr 18.

Published in final edited form as: Nature. 2024 Feb; 626(8001): 1102–1107. Published online 2024 Feb 14. doi: 10.1038/s41586-024-07047-2

PMCID:: PMC11025016

Abstract Article PDF–5.5M

Select item 108808163.

Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer

Maria Zagorulya, Leon Yim, Duncan M. Morgan, Austin Edwards, Elen Torres-Mejia, Noor Momin, Chloe V. McCreery, Izabella L. Zamora, Brendan L. Horton, James G. Fox, K. Dane Wittrup, J. Christopher Love, Stefani Spranger

Immunity. Author manuscript; available in PMC 2024 Feb 21.

Published in final edited form as: Immunity. 2023 Feb 14; 56(2): 386–405.e10. Published online 2023 Feb 2. doi: 10.1016/j.immuni.2023.01.010

PMCID:: PMC10880816

Abstract Article PDF–3.2M

Select item 108797144.

Dendritic cells overcome Cre/Lox induced gene deficiency by siphoning cytosolic material from surrounding cells

Christopher H. Herbst, Aurélie Bouteau, Evelin J. Menykő, Zhen Qin, Ervin Gyenge, Qingtai Su, Vincent Cooper, Neil A. Mabbott, Botond Z. Igyártó

iScience. 2024 Mar 15; 27(3): 109119. Published online 2024 Feb 6. doi: 10.1016/j.isci.2024.109119

PMCID:: PMC10879714

Abstract Article PDF–5.1M

Select item 108523435.

Expression of MHC II in DRG neurons attenuates paclitaxel-induced cold hypersensitivity in male and female mice

Emily E. Whitaker, Neal E. Mecum, Riley C. Cott, Diana J. Goode

PLoS One. 2024; 19(2): e0298396. Published online 2024 Feb 8. doi: 10.1371/journal.pone.0298396

PMCID:: PMC10852343

Abstract Article PDF–4.5M

Select item 108367696.

NLGN4X TCR transgenic T cells to treat gliomas

Christoper Krämer, Michael Kilian, Yu-Chan Chih, Alexandros Kourtesakis, Dirk C Hoffmann, Tamara Boschert, Philipp Koopmann, Khwab Sanghvi, Alice De Roia, Stefanie Jung, Kristine Jähne, Bryan Day, Lenny D Shultz, Miriam Ratliff, Richard Harbottle, Edward W Green, Rainer Will, Wolfgang Wick, Michael Platten, Lukas Bunse

Neuro Oncol. 2024 Feb; 26(2): 266–278. Published online 2023 Sep 16. doi: 10.1093/neuonc/noad172

PMCID:: PMC10836769

Abstract Article PDF–3.4M

Select item 107621547.

MCT1-governed pyruvate metabolism is essential for antibody class-switch recombination through H3K27 acetylation

Wenna Chi, Na Kang, Linlin Sheng, Sichen Liu, Lei Tao, Xizhi Cao, Ye Liu, Can Zhu, Yuming Zhang, Bolong Wu, Ruiqun Chen, Lili Cheng, Jing Wang, Xiaolin Sun, Xiaohui Liu, Haiteng Deng, Jinliang Yang, Zhanguo Li, Wanli Liu, Ligong Chen

Nat Commun. 2024; 15: 163. Published online 2024 Jan 2. doi: 10.1038/s41467-023-44540-0

PMCID:: PMC10762154

Abstract Article PDF–3.1M

Select item 106429518.

Multimodal control of dendritic cell functions by nociceptors

Pavel Hanč, Rodrigo J. Gonzalez, Irina B. Mazo, Yidi Wang, Talley Lambert, Gloria Ortiz, Evan W. Miller, Ulrich H. von Andrian

Science. Author manuscript; available in PMC 2023 Nov 13.

Published in final edited form as: Science. 2023 Mar 31; 379(6639): eabm5658. Published online 2023 Mar 31. doi: 10.1126/science.abm5658

PMCID:: PMC10642951

Abstract Article PDF–2.7M

Select item 106235819.

I-A^g7 β56/57 polymorphisms regulate non-cognate negative selection to CD4 T cell orchestrators of type-1 diabetes

Brian D. Stadinski, Sarah B. Cleveland, Michael A. Brehm, Dale L. Greiner, Priya G. Huseby, Eric S. Huseby

Nat Immunol. Author manuscript; available in PMC 2023 Nov 3.

Published in final edited form as: Nat Immunol. 2023 Apr; 24(4): 652–663. Published online 2023 Feb 20. doi: 10.1038/s41590-023-01441-0

PMCID:: PMC10623581

Abstract Article PDF–4.1M

Select item 1053878710.

Interactions between B cells and T follicular regulatory cells enhance susceptibility to Brucella infection independent of the anti-Brucella humoral response

Alexis S. Dadelahi, Mostafa F. N. Abushahba, Bárbara Ponzilacqua-Silva, Catherine A. Chambers, Charles R. Moley, Carolyn A. Lacey, Alexander L. Dent, Jerod A. Skyberg

PLoS Pathog. 2023 Sep; 19(9): e1011672. Published online 2023 Sep 18. doi: 10.1371/journal.ppat.1011672

PMCID:: PMC10538787

Abstract Article PDF–2.7M

Select item 1053037211.

Intestinal Microbiota Controls Graft-versus-Host Disease Independent of Donor-Host Genetic Disparity

Motoko Koyama, Daniel S Hippe, Sujatha Srinivasan, Sean C Proll, Oriana Miltiadous, Naisi Li, Ping Zhang, Kathleen S Ensbey, Noah G Hoffman, Christine R Schmidt, Albert C Yeh, Simone A Minnie, Susan M Strenk, Tina L Fiedler, Namita Hattangady, Jacob Kowalsky, Willian M Grady, Mariapia A Degli-Esposti, Antiopi Varelias, Andrew D Clouston, Marcel R M van den Brink, Neelendu Dey, Timothy W Randolph, Kate A Markey, David N Fredricks, Geoffrey R Hill

Immunity. Author manuscript; available in PMC 2024 Aug 8.

Published in final edited form as: Immunity. 2023 Aug 8; 56(8): 1876–1893.e8. Published online 2023 Jul 21. doi: 10.1016/j.immuni.2023.06.024

PMCID:: PMC10530372

Abstract Article PDF–1.7M

Select item 1047627912.

Gut microbiota regulates blood‐cerebrospinal fluid barrier function and Aβ pathology

Junhua Xie, Arnout Bruggeman, Clint De Nolf, Charysse Vandendriessche, Griet Van Imschoot, Elien Van Wonterghem, Lars Vereecke, Roosmarijn E Vandenbroucke

EMBO J. 2023 Sep; 42(17): e111515. Published online 2023 Jul 10. doi: 10.15252/embj.2022111515

PMCID:: PMC10476279

Abstract Article PDF–20M

Select item 1039867113.

Two structurally defined Aβ polymorphs promote different pathological changes in susceptible mice

Ruben Gomez‐Gutierrez, Ujjayini Ghosh, Wai‐Ming Yau, Nazaret Gamez, Katherine Do, Carlos Kramm, Hamid Shirani, Laura Vegas‐Gomez, Jonathan Schulz, Ines Moreno‐Gonzalez, Antonia Gutierrez, K Peter R Nilsson, Robert Tycko, Claudio Soto, Rodrigo Morales

EMBO Rep. 2023 Aug; 24(8): e57003. Published online 2023 Jul 10. doi: 10.15252/embr.202357003

PMCID:: PMC10398671

Abstract Article PDF–4.4M

Select item 1029321414.

Border-associated macrophages mediate the neuroinflammatory response in an alpha-synuclein model of Parkinson disease

A. M. Schonhoff, D. A. Figge, G. P. Williams, A. Jurkuvenaite, N. J. Gallups, G. M. Childers, J. M. Webster, D. G. Standaert, J. E. Goldman, A. S. Harms

Nat Commun. 2023; 14: 3754. Published online 2023 Jun 26. doi: 10.1038/s41467-023-39060-w

PMCID:: PMC10293214

Abstract Article PDF–11M

Select item 1028107615.

T helper 1 effector memory CD4⁺ T cells protect the skin from poxvirus infection

Jake C. Harbour, Mahmoud Abdelbary, John B. Schell, Samantha P. Fancher, Jack J. McLean, Taylen J. Nappi, Susan Liu, Timothy J. Nice, Zheng Xia, Klaus Früh, Jeffrey C. Nolz

Cell Rep. Author manuscript; available in PMC 2023 Jun 20.

Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112407. Published online 2023 Apr 21. doi: 10.1016/j.celrep.2023.112407

PMCID:: PMC10281076

Abstract Article PDF–3.6M

Select item 1024258416.

Simultaneous evaluation of treatment efficacy and toxicity for bispecific T-cell engager therapeutics in a humanized mouse model

Jiwon Yang, Jing Jiao, Kyle M. Draheim, Guoxiang Yang, Hongyuan Yang, Li-Chin Yao, Leonard D. Shultz, Dale L. Greiner, Deepa Rajagopal, Sandrine Vessillier, Curtis C. Maier, Sunish Mohanan, Danying Cai, Mingshan Cheng, Michael A. Brehm, James G. Keck

FASEB J. Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: FASEB J. 2023 Jun; 37(6): e22995. doi: 10.1096/fj.202300040R

PMCID:: PMC10242584

Abstract Article PDF–1.6M

Select item 1015691317.

CARD 19, a novel regulator of the TAK1/NF-κB pathway in self-reactive B cells

Yongwei Zheng, Mei Yu, Yuhong Chen, Liquan Xue, Wen Zhu, Guoping Fu, Stephan W Morris, Renren Wen, Demin Wang

J Immunol. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: J Immunol. 2023 May 1; 210(9): 1222–1235. doi: 10.4049/jimmunol.2200639

PMCID:: PMC10156913

Abstract Article PDF–4.9M

Select item 994689718.

Prolidase Deficiency Causes Spontaneous T Cell Activation and Lupus-like Autoimmunity

Rose Hodgson, Tanya L. Crockford, Aneesha Bhandari, Jessica D. Kepple, Jennifer Back, Eleanor Cawthorne, Lucie Abeler-Dörner, Adam G. Laing, Simon Clare, Anneliese Speak, David J. Adams, Gordon Dougan, Adrian C. Hayday, Mukta Deobagkar-Lele, Richard J. Cornall, Katherine R. Bull

J Immunol. 2023 Mar 1; 210(5): 547–557. Published online 2023 Jan 11. doi: 10.4049/jimmunol.2200212

PMCID:: PMC9946897

Abstract Article PDF–1.5M

Select item 992795019.

Intestinal epithelial HDAC3 and MHC class II coordinate microbiota-specific immunity

Emily M. Eshleman, Tzu-Yu Shao, Vivienne Woo, Taylor Rice, Laura Engleman, Bailey J. Didriksen, Jordan Whitt, David B. Haslam, Sing Sing Way, Theresa Alenghat

J Clin Invest. 2023 Feb 15; 133(4): e162190. Published online 2023 Feb 15. doi: 10.1172/JCI162190

PMCID:: PMC9927950

Abstract Article PDF–4.5M

Select item 976094820.

Citrullinated glucose-regulated protein 78 is a candidate target for melanoma immunotherapy

Victoria Anne Brentville, Peter Symonds, JiaXin Chua, Anne Skinner, Ian Daniels, Katherine Wendy Cook, Sasa Koncarevic, Roxana Martinez-Pinna, Sabaria Shah, Ruhul Hasan Choudhury, Poonam Vaghela, Daisy Weston, Abdullah Al-Omari, James Davis, Lindy G. Durrant

Front Immunol. 2022; 13: 1066185. Published online 2022 Dec 5. doi: 10.3389/fimmu.2022.1066185

PMCID:: PMC9760948

Abstract Article PDF–2.4M

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