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Select item 109332011.

Crosstalk between purinergic receptor P2Y₁₁ and chemokine receptor CXCR7 is regulated by CXCR4 in human macrophages

Dominik Klaver, Hubert Gander, Beatrice Frena, Marco Amato, Martin Thurnher

Cell Mol Life Sci. 2024 Dec; 81(1): 132. Published online 2024 Mar 13. doi: 10.1007/s00018-024-05158-7

PMCID:: PMC10933201

Abstract Article PDF–4.5M

Select item 106904702.

Systematic P2Y receptor survey identifies P2Y11 as modulator of immune responses and virus replication in macrophages

Line Lykke Andersen, Yiqi Huang, Christian Urban, Lila Oubraham, Elena Winheim, Che Stafford, Dennis Nagl, Fionan O'Duill, Thomas Ebert, Thomas Engleitner, Søren Riis Paludan, Anne Krug, Roland Rad, Veit Hornung, Andreas Pichlmair

EMBO J. 2023 Dec; 42(23): e113279. Published online 2023 Oct 26. doi: 10.15252/embj.2022113279

PMCID:: PMC10690470

Abstract Article PDF–2.0M

Select item 100736263.

P2Y₁₁/IL-1 receptor crosstalk controls macrophage inflammation: a novel target for anti-inflammatory strategies?

Dominik Klaver, Martin Thurnher

Purinergic Signal. 2023 Sep; 19(3): 501–511. Published online 2023 Apr 5. doi: 10.1007/s11302-023-09932-3

PMCID:: PMC10073626

Abstract Article PDF–929K

Select item 94764234.

The P2Y₁₁ receptor of human M2 macrophages activates canonical and IL-1 receptor signaling to translate the extracellular danger signal ATP into anti-inflammatory and pro-angiogenic responses

Dominik Klaver, Hubert Gander, Gabriele Dobler, Andrea Rahm, Martin Thurnher

Cell Mol Life Sci. 2022; 79(10): 519. Published online 2022 Sep 15. doi: 10.1007/s00018-022-04548-z

PMCID:: PMC9476423

Abstract Article PDF–2.3M

Select item 88267735.

The purinergic receptor P2Y11 choreographs the polarization, mitochondrial metabolism, and migration of T lymphocytes

Carola Ledderose, Sophie Bromberger, Christian J. Slubowski, Koichiro Sueyoshi, Dilan Aytan, Yong Shen, Wolfgang G. Junger

Sci Signal. Author manuscript; available in PMC 2022 Feb 9.

Published in final edited form as: Sci Signal. 2020 Sep 29; 13(651): eaba3300. Published online 2020 Sep 29. doi: 10.1126/scisignal.aba3300

PMCID:: PMC8826773

Abstract Article PDF–1.3M

Select item 87722876.

P2Y11 receptors support T cell activation by directing mitochondrial trafficking to the immune synapse

Carola Ledderose, Sophie Bromberger, Christian J. Slubowski, Koichiro Sueyoshi, Wolfgang G. Junger

J Leukoc Biol. Author manuscript; available in PMC 2022 Jan 20.

Published in final edited form as: J Leukoc Biol. 2021 Mar; 109(3): 497–508. Published online 2020 Jun 12. doi: 10.1002/JLB.2HI0520-191R

PMCID:: PMC8772287

Abstract Article PDF–2.1M

Select item 83613457.

High nocturnal sleep fragmentation is associated with low T lymphocyte P2Y₁₁ protein levels in narcolepsy type 1

Rannveig Viste, Marte K Viken, Benedicte A Lie, Hilde T Juvodden, Sebjørg E H Nordstrand, Per M Thorsby, Terje Rootwelt, Birgitte R Kornum, Stine Knudsen-Heier

Sleep. 2021 Aug; 44(8): zsab062. Published online 2021 Mar 12. doi: 10.1093/sleep/zsab062

PMCID:: PMC8361345

Abstract Article PDF–4.2M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 67781379.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 669555710.

The Human G Protein-Coupled ATP Receptor P2Y₁₁ Is Associated With IL-10 Driven Macrophage Differentiation

Georg Gruenbacher, Hubert Gander, Andrea Rahm, Gabriele Dobler, Astrid Drasche, Jakob Troppmair, Walter Nussbaumer, Martin Thurnher

Front Immunol. 2019; 10: 1870. Published online 2019 Aug 9. doi: 10.3389/fimmu.2019.01870

PMCID:: PMC6695557

Abstract Article PDF–3.0M

Select item 648412011.

Lipopolysaccharide suppresses T cells by generating extracellular ATP that impairs their mitochondrial function via P2Y11 receptors

Koichiro Sueyoshi, Carola Ledderose, Yong Shen, Albert H. Lee, Nathan I. Shapiro, Wolfgang G. Junger

J Biol Chem. 2019 Apr 19; 294(16): 6283–6293. Published online 2019 Feb 20. doi: 10.1074/jbc.RA118.007188

PMCID:: PMC6484120

Abstract Article PDF–2.0M

Select item 646186412.

LncRNAs-directed PTEN enzymatic switch governs epithelial–mesenchymal transition

Qingsong Hu, Chunlai Li, Shouyu Wang, Yajuan Li, Bo Wen, Yanyan Zhang, Ke Liang, Jun Yao, Youqiong Ye, Heidi Hsiao, Tina K. Nguyen, Peter K. Park, Sergey D. Egranov, David H. Hawke, Jeffrey R. Marks, Leng Han, Mien-Chie Hung, Bing Zhang, Chunru Lin, Liuqing Yang

Cell Res. 2019 Apr; 29(4): 286–304. Published online 2019 Jan 10. doi: 10.1038/s41422-018-0134-3

PMCID:: PMC6461864

Abstract Article PDF–11M

Select item 600248413.

Human P2Y₁₁ Expression Level Affects Human P2X7 Receptor-Mediated Cell Death

Karin Dreisig, Louise Sund, Maja Wallentin Dommer, Nikolaj Pagh Kristensen, Kim Boddum, Rannveig Viste, Simon Fredholm, Niels Odum, Marja Jäättelä, Søren Skov, Birgitte R. Kornum

Front Immunol. 2018; 9: 1159. Published online 2018 Jun 8. doi: 10.3389/fimmu.2018.01159

PMCID:: PMC6002484

Abstract Article PDF–2.1M

Select item 567858114.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 551490815.

Carcinoma-specific expression of P2Y₁₁ receptor and its contribution in ATP-induced purinergic signalling and cell migration in human hepatocellular carcinoma cells

Madiha Khalid, Lucie Brisson, Menahil Tariq, Yunjie Hao, Roseline Guibon, Gaëlle Fromont, Sharifah Alawieyah Syed Mortadza, Fatema Mousawi, Sobia Manzoor, Sébastien Roger, Lin-Hua Jiang

Oncotarget. 2017 Jun 6; 8(23): 37278–37290. Published online 2017 Mar 14. doi: 10.18632/oncotarget.16191

PMCID:: PMC5514908

Abstract Article PDF–4.2M

Select item 500933716.

Activation of P2X7 and P2Y11 purinergic receptors inhibits migration and normalizes tumor-derived endothelial cells via cAMP signaling

D. Avanzato, T. Genova, A. Fiorio Pla, M. Bernardini, S. Bianco, B. Bussolati, D. Mancardi, E. Giraudo, F. Maione, P. Cassoni, I. Castellano, L. Munaron

Sci Rep. 2016; 6: 32602. Published online 2016 Sep 2. doi: 10.1038/srep32602

Correction in:: Sci Rep. 2016; 6: 35897.

PMCID:: PMC5009337

Abstract Article PDF–2.0M

Select item 381431117.

Genome Wide Analysis of Narcolepsy in China Implicates Novel Immune Loci and Reveals Changes in Association Prior to Versus After the 2009 H1N1 Influenza Pandemic

Fang Han, Juliette Faraco, Xiao Song Dong, Hanna M. Ollila, Ling Lin, Jing Li, Pei An, Shan Wang, Ke Wei Jiang, Zhan Cheng Gao, Long Zhao, Han Yan, Ya Nan Liu, Qing Hua Li, Xiao Zhe Zhang, Yan Hu, Jing Yu Wang, Yun Hui Lu, Chang Jun Lu, Wei Zhou, Joachim Hallmayer, Yu Shu Huang, Kingman P. Strohl, Thomas Pollmächer, Emmanuel Mignot

PLoS Genet. 2013 Oct; 9(10): e1003880. Published online 2013 Oct 31. doi: 10.1371/journal.pgen.1003880

PMCID:: PMC3814311

Abstract Article PDF–580K

Select item 361844418.

Autocrine Regulation of Macrophage Activation via Exocytosis of ATP and Activation of P2Y11 Receptor

Hayato Sakaki, Mitsutoshi Tsukimoto, Hitoshi Harada, Yoshinori Moriyama, Shuji Kojima

PLoS One. 2013; 8(4): e59778. Published online 2013 Apr 5. doi: 10.1371/journal.pone.0059778

PMCID:: PMC3618444

Abstract Article PDF–1.6M

Select item 335059419.

Purinergic receptors expressed in human skeletal muscle fibres

A. Bornø, T. Ploug, L. T. Bune, J. B. Rosenmeier, P. Thaning

Purinergic Signal. 2012 Jun; 8(2): 255–264. Published online 2011 Nov 4. doi: 10.1007/s11302-011-9279-y

PMCID:: PMC3350594

Abstract Article PDF–419K

Select item 328827920.

TCRA, P2RY11, and CPT1B/CHKB associations in Chinese narcolepsy

Fang Han, Ling Lin, Jing Li, Adi Aran, Song X. Dong, Pei. An, Long Zhao, Qian Y. Li, Han Yan, Jie S. Wang, Hui Y. Gao, Mei Li, Zhan C. Gao, Kingman P. Strohl, Emmanuel Mignot

Sleep Med. Author manuscript; available in PMC 2013 Mar 1.

Published in final edited form as: Sleep Med. 2012 Mar; 13(3): 269–272. Published online 2011 Dec 15. doi: 10.1016/j.sleep.2011.06.020

PMCID:: PMC3288279

Abstract Article PDF–320K

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