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Select item 109457071.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 105411742.

The chemorepellent, SLIT2, bolsters innate immunity against Staphylococcus aureus

Vikrant K Bhosle, Chunxiang Sun, Sajedabanu Patel, Tse Wing Winnie Ho, Johannes Westman, Dustin A Ammendolia, Fatemeh Mirshafiei Langari, Noah Fine, Nicole Toepfner, Zhubing Li, Manraj Sharma, Judah Glogauer, Mariana I Capurro, Nicola L Jones, Jason T Maynes, Warren L Lee, Michael Glogauer, Sergio Grinstein, Lisa A Robinson

eLife. 2023; 12: e87392. Published online 2023 Sep 29. doi: 10.7554/eLife.87392

PMCID:: PMC10541174

Abstract Article PDF–2.1M

Select item 102794723.

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways

Julie K. Monda, Xuezhen Ge, Moritz Hunkeler, Katherine A. Donovan, Michelle W. Ma, Cyrus Y. Jin, Marilyn Leonard, Eric S. Fischer, Eric J. Bennett

Cell Rep. Author manuscript; available in PMC 2023 Jun 19.

Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112496. Published online 2023 May 9. doi: 10.1016/j.celrep.2023.112496

PMCID:: PMC10279472

Abstract Article PDF–2.9M

Select item 101645644.

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing

Yingxiao Chen, Yanping Li, Roselyn S Dai, Jonathan C Savage, Ujwal Shinde, John Klimek, Larry L David, Emma A Young, Markus Hafner, Rosalie C Sears, Xiao-Xin Sun, Mu-Shui Dai

Nucleic Acids Res. 2023 May 8; 51(8): 3934–3949. Published online 2023 Mar 13. doi: 10.1093/nar/gkad140

PMCID:: PMC10164564

Abstract Article PDF–3.8M

Select item 99995165.

Bone marrow mesenchymal stem cell-derived exosomal microRNA-382 promotes osteogenesis in osteoblast via regulation of SLIT2

Hairong Su, Yulan Yang, Wanchun Lv, Xiaoli Li, Binxiu Zhao

J Orthop Surg Res. 2023; 18: 185. Published online 2023 Mar 10. doi: 10.1186/s13018-023-03667-y

PMCID:: PMC9999516

Abstract Article PDF–4.4M

Select item 96776756.

SLIT2 promoter hypermethylation predicts disease progression in chronic myeloid leukemia

De-long Wu, Yun Wang, Ting-juan Zhang, Ming-qiang Chu, Zi-jun Xu, Qian Yuan, Ji-chun Ma, Jiang Lin, Jun Qian, Jing-dong Zhou

Eur J Med Res. 2022; 27: 259. Published online 2022 Nov 21. doi: 10.1186/s40001-022-00899-2

PMCID:: PMC9677675

Abstract Article PDF–2.7M

Select item 95699557.

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation

Yulemi Gonzalez Quesada, Luc DesGroseillers

Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588

PMCID:: PMC9569955

Abstract Article PDF–2.1M

Select item 92612618.

The Role of Slit-2 in Gestational Diabetes Mellitus and Its Effect on Pregnancy Outcome

Yan Wang, Shihua Zhao, Wei Peng, Ying Chen, Jingwei Chi, Kui Che, Yangang Wang

Front Endocrinol (Lausanne) 2022; 13: 889505. Published online 2022 Jun 23. doi: 10.3389/fendo.2022.889505

PMCID:: PMC9261261

Abstract Article PDF–1.0M

Select item 91197369.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 910523510.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 876688911.

DUCTULAR REACTION PROMOTES INTRAHEPATIC ANGIOGENESIS VIA SLIT2-ROBO1 SIGNALING

Mar Coll, Silvia Ariño, Celia Mártinez-Sánchez, Ester Garcia-Pras, Javier Gallego, Anna Moles, Beatriz Aguilar-Bravo, Delia Blaya, Julia Vallverdú, Teresa Rubio-Tomás, Juan Jose Lozano, Elisa Pose, Isabel Graupera, Andrea Fernández-Vidal, Albert Pol, Ramón Bataller, Jian-Guo Geng, Pere Ginès, Mercedes Fernandez, Pau Sancho-Bru

Hepatology. Author manuscript; available in PMC 2023 Feb 1.

Published in final edited form as: Hepatology. 2022 Feb; 75(2): 353–368. Published online 2021 Dec 15. doi: 10.1002/hep.32140

PMCID:: PMC8766889

Abstract Article PDF–2.4M

Select item 863174212.

Slit2 inhibits breast cancer metastasis by activating M1-like phagocytic and anti-fibrotic macrophages

Dinesh K. Ahirwar, Manish Charan, Sanjay Mishra, Ajeet K. Verma, Konstantin Shilo, Bhuvaneswari Ramaswamy, Ramesh K. Ganju

Cancer Res. Author manuscript; available in PMC 2022 Apr 15.

Published in final edited form as: Cancer Res. 2021 Oct 15; 81(20): 5255–5267. Published online 2021 Aug 16. doi: 10.1158/0008-5472.CAN-20-3909

PMCID:: PMC8631742

Abstract Article PDF–2.3M

Select item 858149213.

Slit2-Mediated Metabolic Reprogramming in Bone Marrow-Derived Macrophages Enhances Antitumor Immunity

Kirti Kaul, Martin Benej, Sanjay Mishra, Dinesh K. Ahirwar, Marshleen Yadav, Kristin I. Stanford, Naduparambil K. Jacob, Nicholas C. Denko, Ramesh K. Ganju

Front Immunol. 2021; 12: 753477. Published online 2021 Oct 28. doi: 10.3389/fimmu.2021.753477

PMCID:: PMC8581492

Abstract Article PDF–2.5M

Select item 855290714.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 851385315.

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari

PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412

PMCID:: PMC8513853

Abstract Article PDF–4.1M

Select item 837635716.

Expression of the axon guidance factor Slit2 and its receptor Robo1 in patients with Hirschsprung disease: An observational study

Meng Kong, Tao Zhou, Bo Xiang

Medicine (Baltimore) 2021 Aug 20; 100(33): e26981. Published online 2021 Aug 20. doi: 10.1097/MD.0000000000026981

PMCID:: PMC8376357

Abstract Article PDF–717K

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 808882818.

Tumoural activation of TLR3-SLIT2 axis in endothelium drives metastasis

Bernardo Tavora, Tobias Mederer, Kai Wessel, Simon Ruffing, Mahan Sadjadi, Marc Missmahl, Benjamin N. Ostendorf, Xuhang Liu, Ji-Young Kim, Olav Olsen, Alana L. Welm, Hani Goodarzi, Sohail F. Tavazoie

Nature. Author manuscript; available in PMC 2021 May 2.

Published in final edited form as: Nature. 2020 Oct; 586(7828): 299–304. Published online 2020 Sep 30. doi: 10.1038/s41586-020-2774-y

PMCID:: PMC8088828

Abstract Article PDF–4.3M

Select item 787873319.

The neurorepellent, Slit2, prevents macrophage lipid loading by inhibiting CD36-dependent binding and internalization of oxidized low-density lipoprotein

Bushra Yusuf, Ilya Mukovozov, Sajedabanu Patel, Yi-Wei Huang, Guang Ying Liu, Emily C. Reddy, Marko Skrtic, Michael Glogauer, Lisa A. Robinson

Sci Rep. 2021; 11: 3614. Published online 2021 Feb 11. doi: 10.1038/s41598-021-83046-x

PMCID:: PMC7878733

Abstract Article PDF–2.8M

Select item 783558620.

Crosstalk between the activated Slit2–Robo1 pathway and TGF‐β1 signalling promotes cardiac fibrosis

Yunqi Liu, Ziwei Yin, Xueqin Xu, Chen Liu, Xiaoying Duan, Qinlan Song, Ying Tuo, Cuiping Wang, Jing Yang, Shengli Yin

ESC Heart Fail. 2021 Feb; 8(1): 447–460. Published online 2020 Nov 24. doi: 10.1002/ehf2.13095

PMCID:: PMC7835586

Abstract Article PDF–34M

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