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Select item 112415201.

In Silico Electrophysiological Investigation of Transient Receptor Potential Melastatin-4 Ion Channel Biophysics to Study Detrusor Overactivity

Chitaranjan Mahapatra, Ravindra Thakkar

Int J Mol Sci. 2024 Jul; 25(13): 6875. Published online 2024 Jun 22. doi: 10.3390/ijms25136875

PMCID:: PMC11241520

Abstract Article PDF–4.3M

Select item 106355912.

Plasma Membrane Channel TRPM4 Mediates Immunogenic Therapy-induced Necrosis

Santanu Ghosh, Rachel Yang, Darjan Duraki, Junyao Zhu, Ji Eun Kim, Musarrat Jabeen, Chengjian Mao, Xinyi Dai, Mara R. Livezey, Matthew W. Boudreau, Ben H. Park, Erik R. Nelson, Paul J. Hergenrother, David J. Shapiro

Cancer Res. Author manuscript; available in PMC 2024 Mar 15.

Published in final edited form as: Cancer Res. 2023 Sep 15; 83(18): 3115–3130. doi: 10.1158/0008-5472.CAN-23-0157

PMCID:: PMC10635591

Abstract Article PDF–2.0M

Select item 104425223.

Knockdown of the TRPM4 channel alters cardiac electrophysiology and hemodynamics in a sex‐ and age‐dependent manner in mice

Prakash Arullampalam, Maria C. Essers, Mey Boukenna, Sabrina Guichard, Jean‐Sébastien Rougier, Hugues Abriel

Physiol Rep. 2023 Aug; 11(16): e15783. Published online 2023 Aug 21. doi: 10.14814/phy2.15783

PMCID:: PMC10442522

Abstract Article PDF–6.9M

Select item 101345454.

TRPM4 regulates hilar mossy cell loss in temporal lobe epilepsy

Laura Mundrucz, Angéla Kecskés, Nóra Henn-Mike, Péter Kóbor, Péter Buzás, Rudi Vennekens, Miklós Kecskés

BMC Biol. 2023; 21: 96. Published online 2023 Apr 26. doi: 10.1186/s12915-023-01604-3

PMCID:: PMC10134545

Abstract Article PDF–5.3M

Select item 100735135.

Defining the role of TRPM4 in broadly responsive taste receptor cells

Debarghya Dutta Banik, Kathryn F. Medler

Front Cell Neurosci. 2023; 17: 1148995. Published online 2023 Mar 22. doi: 10.3389/fncel.2023.1148995

PMCID:: PMC10073513

Abstract Article PDF–2.7M

Select item 99459776.

Faulty TRPM4 channels underlie age-dependent cerebral vascular dysfunction in Gould syndrome

Evan Yamasaki, Sher Ali, Alfredo Sanchez Solano, Pratish Thakore, Megan Smith, Xiaowei Wang, Cassandre Labelle-Dumais, Douglas B. Gould, Scott Earley

Proc Natl Acad Sci U S A. 2023 Jan 31; 120(5): e2217327120. Published online 2023 Jan 24. doi: 10.1073/pnas.2217327120

PMCID:: PMC9945977

Abstract Article PDF–2.7M

Select item 96324387.

Gain-of-function of TRPM4 predisposes mice to psoriasiform dermatitis

Daisuke Yamada, Simon Vu, Xuesong Wu, Zhenrui Shi, Desiree Morris, Joshua D. Bloomstein, Mindy Huynh, Jie Zheng, Samuel T. Hwang

Front Immunol. 2022; 13: 1025499. Published online 2022 Oct 20. doi: 10.3389/fimmu.2022.1025499

PMCID:: PMC9632438

Abstract Article PDF–8.1M

Select item 94382808.

Flufenamic acid improves survival and neurologic outcome after successful cardiopulmonary resuscitation in mice

Jiancong Chen, Yuan Chang, Juan Zhu, Yuqin Peng, Zheqi Li, Kunxue Zhang, Yuzhen Zhang, Chuman Lin, Zhenzhou Lin, Suyue Pan, Kaibin Huang

J Neuroinflammation. 2022; 19: 214. Published online 2022 Sep 1. doi: 10.1186/s12974-022-02571-2

PMCID:: PMC9438280

Abstract Article PDF–13M

Select item 90084869.

Emergent Temporal Signaling in Human Trabecular Meshwork Cells: Role of TRPV4-TRPM4 Interactions

Oleg Yarishkin, Tam T. T. Phuong, Felix Vazquez-Chona, Jacques Bertrand, Joseph van Battenburg-Sherwood, Sarah N. Redmon, Christopher N. Rudzitis, Monika Lakk, Jackson M. Baumann, Marc Freichel, Eun-Mi Hwang, Darryl Overby, David Križaj

Front Immunol. 2022; 13: 805076. Published online 2022 Mar 31. doi: 10.3389/fimmu.2022.805076

PMCID:: PMC9008486

Abstract Article PDF–5.0M

Select item 899478310.

A glibenclamide-sensitive TRPM4-mediated component of CA1 excitatory postsynaptic potentials appears in experimental autoimmune encephalomyelitis

Brenna C. Fearey, Lars Binkle, Daniel Mensching, Christian Schulze, Christian Lohr, Manuel A. Friese, Thomas G. Oertner, Christine E. Gee

Sci Rep. 2022; 12: 6000. Published online 2022 Apr 9. doi: 10.1038/s41598-022-09875-6

PMCID:: PMC8994783

Abstract Article PDF–2.5M

Select item 860791111.

TRPM4 Contributes to Subthreshold Membrane Potential Oscillations in Multiple Mouse Pacemaker Neurons

Keyong Li, Yingtang Shi, Elizabeth C. Gonye, Douglas A. Bayliss

eNeuro. 2021 Nov-Dec; 8(6): ENEURO.0212-21.2021. Prepublished online 2021 Nov 2. Published online 2021 Nov 12. doi: 10.1523/ENEURO.0212-21.2021

PMCID:: PMC8607911

Abstract Article PDF–2.9M

Select item 853429312.

HIV-1 Vpr-Induced Proinflammatory Response and Apoptosis Are Mediated through the Sur1-Trpm4 Channel in Astrocytes

Ge Li, Tapas Makar, Volodymyr Gerzanich, Sudhakar Kalakonda, Svetlana Ivanova, Edna F. R. Pereira, Sanketh Andharvarapu, Jiantao Zhang, J. Marc Simard, Richard Y. Zhao

mBio. 2020 Nov-Dec; 11(6): e02939-20. Published online 2020 Dec 8. doi: 10.1128/mBio.02939-20

PMCID:: PMC8534293

Abstract Article PDF–3.1M

Select item 849230813.

Attenuation of cerebral edema facilitates recovery of glymphatic system function after status epilepticus

Kewei Liu, Juan Zhu, Yuan Chang, Zhenzhou Lin, Zhu Shi, Xing Li, Xing Chen, Chuman Lin, Suyue Pan, Kaibin Huang

JCI Insight. 2021 Sep 8; 6(17): e151835. Published online 2021 Sep 8. doi: 10.1172/jci.insight.151835

PMCID:: PMC8492308

Abstract Article PDF–5.0M

Select item 837120614.

TRPM4 links calcium signaling to membrane potential in pancreatic acinar cells

Gyula Diszházi, Zsuzsanna É. Magyar, Erika Lisztes, Edit Tóth-Molnár, Péter P. Nánási, Rudi Vennekens, Balázs I. Tóth, János Almássy

J Biol Chem. 2021 Sep; 297(3): 101015. Published online 2021 Jul 27. doi: 10.1016/j.jbc.2021.101015

PMCID:: PMC8371206

Abstract Article PDF–1.0M

Select item 824513315.

The Ca²⁺-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy

Yang Guo, Ze-Yan Yu, Jianxin Wu, Hutao Gong, Scott Kesteven, Siiri E Iismaa, Andrea Y Chan, Sara Holman, Silvia Pinto, Andy Pironet, Charles D Cox, Robert M Graham, Rudi Vennekens, Michael P Feneley, Boris Martinac

eLife. 2021; 10: e66582. Published online 2021 Jun 30. doi: 10.7554/eLife.66582