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Items: 1 to 20 of 24

1.
The AMPK-related kinase NUAK1 controls cortical axons branching by locally modulating mitochondrial metabolic functions
Marine Lanfranchi, Sozerko Yandiev, Géraldine Meyer-Dilhet, Salma Ellouze, Martijn Kerkhofs, Raphael Dos Reis, Audrey Garcia, Camille Blondet, Alizée Amar, Anita Kneppers, Hélène Polvèche, Damien Plassard, Marc Foretz, Benoit Viollet, Kei Sakamoto, Rémi Mounier, Cyril F. Bourgeois, Olivier Raineteau, Evelyne Goillot, Julien Courchet
Nat Commun. 2024; 15: 2487. Published online 2024 Mar 21. doi: 10.1038/s41467-024-46146-6
PMCID:
PMC10958033
AbstractArticlePDF–5.0M
2.
Enhanced Expression of ARK5 in Hepatic Stellate Cell and Hepatocyte Synergistically Promote Liver Fibrosis
Yang You, Chongqing Gao, Junru Wu, Hengdong Qu, Yang Xiao, Ziwei Kang, Jinying Li, Jian Hong
Int J Mol Sci. 2022 Nov; 23(21): 13084. Published online 2022 Oct 28. doi: 10.3390/ijms232113084
PMCID:
PMC9655442
AbstractArticlePDF–4.9M
3.
Loss of LKB1-NUAK1 signalling enhances NF-κB activity in a spheroid model of high-grade serous ovarian cancer
Adrian Buensuceso, Jamie Lee Fritz, Olga Collins, Yudith Ramos Valdés, Matthew J. Borrelli, Gabriel E. DiMattia, Trevor G. Shepherd
Sci Rep. 2022; 12: 3011. Published online 2022 Feb 22. doi: 10.1038/s41598-022-06796-2
PMCID:
PMC8863794
AbstractArticlePDF–8.5M
4.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
5.
High-throughput kinase inhibitor screening reveals roles for Aurora and Nuak kinases in neurite initiation and dendritic branching
Sara M. Blazejewski, Sarah A. Bennison, Xiaonan Liu, Kazuhito Toyo-oka
Sci Rep. 2021; 11: 8156. Published online 2021 Apr 14. doi: 10.1038/s41598-021-87521-3
PMCID:
PMC8047044
AbstractArticlePDF–3.7M
6.
STK11 is required for the normal program of ciliated cell differentiation in airways
Qiqi Chu, Changfu Yao, Xiangbing Qi, Barry Raymond Stripp, Nan Tang
Cell Discov. 2019; 5: 36. Published online 2019 Jul 16. doi: 10.1038/s41421-019-0104-z
PMCID:
PMC6796922
AbstractArticlePDF–4.6M
7.
Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility
Ana Angulo-Urarte, Pedro Casado, Sandra D. Castillo, Piotr Kobialka, Maria Paraskevi Kotini, Ana M. Figueiredo, Pau Castel, Vinothini Rajeeve, Maria Milà-Guasch, Jaime Millan, Cora Wiesner, Helena Serra, Laia Muixi, Oriol Casanovas, Francesc Viñals, Markus Affolter, Holger Gerhardt, Stephan Huveneers, Heinz-Georg Belting, Pedro R. Cutillas, Mariona Graupera
Nat Commun. 2018; 9: 4826. Published online 2018 Nov 16. doi: 10.1038/s41467-018-07172-3
PMCID:
PMC6240100
AbstractArticlePDF–7.8M
8.
Haploinsufficiency of autism spectrum disorder candidate gene NUAK1 impairs cortical development and behavior in mice
Virginie Courchet, Amanda J. Roberts, Géraldine Meyer-Dilhet, Peggy Del Carmine, Tommy L. Lewis, Jr, Franck Polleux, Julien Courchet
Nat Commun. 2018; 9: 4289. Published online 2018 Oct 16. doi: 10.1038/s41467-018-06584-5
PMCID:
PMC6191442
AbstractArticlePDF–7.3M
9.
Colorectal tumors require NUAK1 for protection from oxidative stress
Jennifer Port, Nathiya Muthalagu, Meera Raja, Fatih Ceteci, Tiziana Monteverde, Bjorn Kruspig, Ann Hedley, Gabriela Kalna, Sergio Lilla, Lisa Neilson, Martina Brucoli, Katarina Gyuraszova, Jacqueline Tait-Mulder, Mokdad Mezna, Silvija Svambaryte, Amy Bryson, David Sumpton, Allan McVie, Colin Nixon, Martin Drysdale, Hiroyasu Esumi, Graeme I. Murray, Owen J. Sansom, Sara R. Zanivan, Daniel J. Murphy
Cancer Discov. Author manuscript; available in PMC 2018 Nov 1.
Published in final edited form as: Cancer Discov. 2018 May; 8(5): 632–647. Published online 2018 Mar 2. doi: 10.1158/2159-8290.CD-17-0533
PMCID:
PMC5935231
AbstractArticlePDF–3.1M
10.
Reduction of Nuak1 decreases tau and reverses phenotypes in a tauopathy mouse model
Cristian A. Lasagna-Reeves, Maria de Haro, Shuang Hao, Jeehye Park, Maxime W.C. Rousseaux, Ismael Al-Ramahi, Paymaan Jafar-Nejad, Luis Vilanova-Velez, Lauren See, Antonia De Maio, Larissa Nitschke, Zhenyu Wu, Juan C. Troncoso, Thomas F. Westbrook, Jianrong Tang, Juan Botas, Huda.Y. Zoghbi
Neuron. Author manuscript; available in PMC 2017 Dec 27.
Published in final edited form as: Neuron. 2016 Oct 19; 92(2): 407–418. Published online 2016 Oct 6. doi: 10.1016/j.neuron.2016.09.022
PMCID:
PMC5745060
AbstractArticlePDF–1.6M
11.
Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle
Iori Sakakibara, Maud Wurmser, Matthieu Dos Santos, Marc Santolini, Serge Ducommun, Romain Davaze, Anthony Guernec, Kei Sakamoto, Pascal Maire
Skelet Muscle. 2016; 6(1): 30. Published online 2016 Sep 5. doi: 10.1186/s13395-016-0102-x
PMCID:
PMC5011358
AbstractArticlePDF–3.5M
12.
Role of miR-211 in Neuronal Differentiation and Viability: Implications to Pathogenesis of Alzheimer’s Disease
Chunying Fan, Qi Wu, Xiaoyang Ye, Hongxue Luo, Dongdong Yan, Yi Xiong, Haili Zhu, Yarui Diao, Wei Zhang, Jun Wan
Front Aging Neurosci. 2016; 8: 166. Published online 2016 Jul 8. doi: 10.3389/fnagi.2016.00166
PMCID:
PMC4937029
AbstractArticlePDF–3.5M
13.
Terminal axon branching is regulated by the LKB1-NUAK1 kinase pathway via presynaptic mitochondrial capture
Julien Courchet, Tommy Lewis, Jr., Sohyon Lee, Virginie Courchet, Deng-Yuan Liou, Shinichi Aizawa, Franck Polleux
Cell. Author manuscript; available in PMC 2014 Jun 20.
Published in final edited form as: Cell. 2013 Jun 20; 153(7): 1510–1525. doi: 10.1016/j.cell.2013.05.021
PMCID:
PMC3729210
AbstractArticlePDF–6.2M
14.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
15.
Muscle-specific Knock-out of NUAK Family SNF1-like Kinase 1 (NUAK1) Prevents High Fat Diet-induced Glucose Intolerance
Fumika Inazuka, Naoyuki Sugiyama, Masaru Tomita, Takaya Abe, Go Shioi, Hiroyasu Esumi
J Biol Chem. 2012 May 11; 287(20): 16379–16389. Published online 2012 Mar 14. doi: 10.1074/jbc.M111.302687
PMCID:
PMC3351321
AbstractArticlePDF–2.6M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
Lhx2 Is Required for Patterning and Expansion of a Distinct Progenitor Cell Population Committed to Eye Development
Anna-Carin Hägglund, Lina Dahl, Leif Carlsson
PLoS One. 2011; 6(8): e23387. Published online 2011 Aug 19. doi: 10.1371/journal.pone.0023387
PMCID:
PMC3158764
AbstractArticlePDF–993K
18.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
19.
Identification of Oscillatory Genes in Somitogenesis from Functional Genomic Analysis of a Human Mesenchymal Stem Cell Model
Dilusha A. William, Biagio Saitta, Joshua D. Gibson, Jeremy Traas, Vladimir Markov, Dorian M. Gonzalez, William Sewell, Douglas M. Anderson, Stephen C. Pratt, Eric F. Rappaport, Kenro Kusumi
Dev Biol. Author manuscript; available in PMC 2007 Jun 25.
Published in final edited form as: Dev Biol. 2007 May 1; 305(1): 172–186. Published online 2007 Feb 14. doi: 10.1016/j.ydbio.2007.02.007
PMCID:
PMC1899184
AbstractArticlePDF–4.8M
20.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K

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