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Select item 113342221.

linc-ADAIN, a human adipose lincRNA, regulates adipogenesis by modulating KLF5 and IL-8 mRNA stability

Marcella E. O’Reilly, Sebastian Ho, Johana Coronel, Lucie Zhu, Wen Liu, Chenyi Xue, Eunyoung Kim, Esther Cynn, Caio V. Matias, Rajesh Kumar Soni, Chen Wang, Iuliana Ionita-Laza, Robert C. Bauer, Leila Ross, Yiying Zhang, Silvia Corvera, Susan K. Fried, Muredach P. Reilly

Cell Rep. Author manuscript; available in PMC 2024 Aug 20.

Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114240. Published online 2024 May 14. doi: 10.1016/j.celrep.2024.114240

PMCID:: PMC11334222

Abstract Article PDF–2.6M

Select item 111914622.

KLF5 inhibits the migration and invasion in cervical cancer cell lines by regulating SNAI1

Xinjian Qu, Chang Xu, Wenbo Yang, Qianqian Li, Simei Tu, Chenghai Gao

Cancer Biomark. 2024; 39(3): 231–243. Prepublished online 2023 Dec 28. Published online 2024 Mar 14. doi: 10.3233/CBM-230175

PMCID:: PMC11191462

Abstract Article PDF–1.7M

Select item 111157493.

Essential role of KLF5 transcription factor in cell proliferation and differentiation and its implications for human diseases

Jin-Tang Dong, Ceshi Chen

Cell Mol Life Sci. 2009 Aug; 66(16): 2691–2706. Published online 2009 May 16. doi: 10.1007/s00018-009-0045-z

PMCID:: PMC11115749

Abstract Article PDF–371K

Select item 110908554.

Abrogation of KLF5 sensitizes BRCA1-proficient pancreatic cancer to PARP inhibition : KLF5 mediates sensitivity to PARP in BRCA1-proficient PDAC

Zheng Zhang, Yuxin Liu, Yaolin Xu, Zijin Xu, Jinbin Jia, Yun Jin, Wenquan Wang, Liang Liu

Acta Biochim Biophys Sin (Shanghai) 2024 Apr 25; 56(4): 576–585. Published online 2024 Mar 4. doi: 10.3724/abbs.2023288

PMCID:: PMC11090855

Abstract Article PDF–2.0M

Select item 110208075.

KLF5 promotes the ossification process of ligamentum flavum by transcriptionally activating CX43

Hubing Guo, Lingxia Yang, Jin Liu, Liqi Chen, Yufeng Huang, Jinsong Li

J Orthop Surg Res. 2024; 19: 244. Published online 2024 Apr 16. doi: 10.1186/s13018-024-04702-2

PMCID:: PMC11020807

Abstract Article PDF–5.9M

Select item 110103596.

Depression of LncRNA DANCR alleviates tubular injury in diabetic nephropathy by regulating KLF5 through sponge miR-214-5p

Yongling Kuang, Juan Yang, Meimei Sun, Tingting Rui, Zhenhua Yang, Meihua Shi

BMC Nephrol. 2024; 25: 130. Published online 2024 Apr 12. doi: 10.1186/s12882-024-03562-6

PMCID:: PMC11010359

Abstract Article PDF–1.4M

Select item 106251207.

KLF5 Promotes Tumor Progression and Parp Inhibitor Resistance in Ovarian Cancer

Yong Wu, Siyu Chen, Yang Shao, Ying Su, Qin Li, Jiangchun Wu, Jun Zhu, Hao Wen, Yan Huang, Zhong Zheng, Xiaojun Chen, Xingzhu Ju, Shenglin Huang, Xiaohua Wu, Zhixiang Hu

Adv Sci (Weinh) 2023 Nov; 10(31): 2304638. Published online 2023 Sep 13. doi: 10.1002/advs.202304638

PMCID:: PMC10625120

Abstract Article PDF–4.3M

Select item 105658768.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 101543569.

KLF5 and p53 comprise an incoherent feed-forward loop directing cell-fate decisions following stress

Yizeng Yang, Dharmendra Bhargava, Xiao Chen, Taicheng Zhou, Gizem Dursuk, Wenpeng Jiang, Jinshen Wang, Zhen Zong, Sharyn I. Katz, Gwen A. Lomberk, Raul A. Urrutia, Jonathan P. Katz

Cell Death Dis. 2023 May; 14(5): 299. Published online 2023 May 2. doi: 10.1038/s41419-023-05731-1

PMCID:: PMC10154356

Abstract Article PDF–2.2M

Select item 1009276910.

Targeting the KLF5-EphA2 axis can restrain cancer stemness and overcome chemoresistance in basal-like breast cancer

Ping Zhao, Jian Sun, Xinwei Huang, Xiangwu Zhang, Xin Liu, Rong Liu, Guangshi Du, Wenqiang Gan, Chuanyu Yang, Yiyin Tang, Ceshi Chen, Dewei Jiang

Int J Biol Sci. 2023; 19(6): 1861–1874. Published online 2023 Mar 21. doi: 10.7150/ijbs.82567

PMCID:: PMC10092769

Abstract Article PDF–6.7M

Select item 983700611.

Tyrosine kinase SRC-induced YAP1-KLF5 module regulates cancer stemness and metastasis in triple-negative breast cancer

Hailin Zou, Juan Luo, Yibo Guo, Tongyu Tong, Yuchen Liu, Yun Chen, Yunjun Xiao, Liping Ye, Chengming Zhu, Liang Deng, Bo Wang, Yihang Pan, Peng Li

Cell Mol Life Sci. 2023 Feb; 80(2): 41. Published online 2023 Jan 12. doi: 10.1007/s00018-023-04688-w

PMCID:: PMC9837006

Abstract Article PDF–16M

Select item 935847412.

A WWP2–PTEN–KLF5 signaling axis regulates odontoblast differentiation and dentinogenesis in mice

Jing Fu, Xiaobo Zhang, Huiwen Zheng, Guobin Yang, Zhi Chen, Guohua Yuan

J Biol Chem. 2022 Aug; 298(8): 102220. Published online 2022 Jul 1. doi: 10.1016/j.jbc.2022.102220

PMCID:: PMC9358474

Abstract Article PDF–3.7M

Select item 917763713.

YB-1 is a positive regulator of KLF5 transcription factor in basal-like breast cancer

Dewei Jiang, Ting Qiu, Junjiang Peng, Siyuan Li, Tala, Wenlong Ren, Chuanyu Yang, Yi Wen, Chuan-Huizi Chen, Jian Sun, Yingying Wu, Rong Liu, Jun Zhou, Kongming Wu, Wen Liu, Xiaoyun Mao, Zhongmei Zhou, Ceshi Chen

Cell Death Differ. 2022 Jun; 29(6): 1283–1295. Published online 2022 Jan 13. doi: 10.1038/s41418-021-00920-x

PMCID:: PMC9177637

Abstract Article PDF–8.5M

Select item 908612614.

Krüppel-Like Factor 5 regulates CFTR expression through repression by maintaining chromatin architecture coupled with direct enhancer activation

Alekh Paranjapye, Monali NandyMazumdar, Ann Harris

J Mol Biol. Author manuscript; available in PMC 2023 May 30.

Published in final edited form as: J Mol Biol. 2022 May 30; 434(10): 167561. Published online 2022 Mar 24. doi: 10.1016/j.jmb.2022.167561

PMCID:: PMC9086126

Abstract Article PDF–1.6M

Select item 902719315.

A New Hypothetical Concept in Metabolic Understanding of Cardiac Fibrosis: Glycolysis Combined with TGF-β and KLF5 Signaling

Thanachai Methatham, Ryozo Nagai, Kenichi Aizawa

Int J Mol Sci. 2022 Apr; 23(8): 4302. Published online 2022 Apr 13. doi: 10.3390/ijms23084302

PMCID:: PMC9027193

Abstract Article PDF–772K

Select item 901855716.

Ketogenesis attenuates KLF5-dependent production of CXCL12 to overcome the immunosuppressive tumor microenvironment in colorectal cancer

Ruozheng Wei, Yuning Zhou, Chang Li, Piotr Rychahou, Shulin Zhang, William B. Titlow, Greg Bauman, Yuanyuan Wu, Jinpeng Liu, Chi Wang, Heidi L. Weiss, B. Mark Evers, Qingding Wang

Cancer Res. Author manuscript; available in PMC 2022 Oct 15.

Published in final edited form as: Cancer Res. 2022 Apr 15; 82(8): 1575–1588. doi: 10.1158/0008-5472.CAN-21-2778

PMCID:: PMC9018557

Abstract Article PDF–2.5M

Select item 898007017.

KLF5 inhibition overcomes oxaliplatin resistance in patient-derived colorectal cancer organoids by restoring apoptotic response

Xiaohui Shen, Yuchen Zhang, Zhuoqing Xu, Han Gao, Wenqing Feng, Wenchang Li, Yiming Miao, Zifeng Xu, Yaping Zong, Jingkun Zhao, Aiguo Lu

Cell Death Dis. 2022 Apr; 13(4): 303. Published online 2022 Apr 5. doi: 10.1038/s41419-022-04773-1

PMCID:: PMC8980070

Abstract Article PDF–6.0M

Select item 897399418.

Krüppel-like factor 5 -mediated Sirtuin6 promotes osteogenic differentiation and inhibits inflammatory injury of lipopolysaccharide-induced periodontal membrane stem cells by inhibiting nuclear factor kappa-B pathway

Chanxiu Li, Feng Xiao, Yunsheng Wen, Jian Wu, Nannan Huang

Bioengineered. 2022; 13(3): 6966–6977. Published online 2022 Mar 7. doi: 10.1080/21655979.2022.2036915

PMCID:: PMC8973994

Abstract Article PDF–2.7M

Select item 893524019.

Histone Deacetylase Inhibitors (HDACi) Promote KLF5 Ubiquitination and Degradation in Basal-like Breast Cancer

Yanjie Kong, Wenlong Ren, Huan Fang, Naseer Ali Shah, Yujie Shi, Dingyun You, Chengang Zhou, Dewei Jiang, Chuanyu Yang, Huichun Liang, Wenjin Liu, Luzhen Wang, Wenqiang Gan, Xing Wan, Fubing Li, Zhen Li, Ceshi Chen, Ni Xie

Int J Biol Sci. 2022; 18(5): 2104–2115. Published online 2022 Feb 28. doi: 10.7150/ijbs.65322

PMCID:: PMC8935240

Abstract Article PDF–2.1M

Select item 882889520.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

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