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Items: 1 to 20 of 241

1.
Low density lipoprotein receptor-related protein 1 couples β1 integrin activation to degradation
Lukasz Wujak, Ralph T. Böttcher, Oleg Pak, Helena Frey, Elie El Agha, Ying Chen, Sigrid Schmitt, Saverio Bellusci, Liliana Schaefer, Norbert ‎Weissmann, Reinhard Fässler, Malgorzata Wygrecka
Cell Mol Life Sci. 2018 May; 75(9): 1671–1685. Published online 2017 Nov 7. doi: 10.1007/s00018-017-2707-6
PMCID:
PMC11105666
AbstractArticlePDF–11M
2.
Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA
Simone Eggert, A. C. Gonzalez, C. Thomas, S. Schilling, S. M. Schwarz, C. Tischer, V. Adam, P. Strecker, V. Schmidt, T. E. Willnow, G. Hermey, C. U. Pietrzik, E. H. Koo, Stefan Kins
Cell Mol Life Sci. 2018 Jan; 75(2): 301–322. Published online 2017 Aug 10. doi: 10.1007/s00018-017-2625-7
PMCID:
PMC11105302
AbstractArticlePDF–6.9M
3.
ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells
Jiyeon Lee, Haeryung Lee, Hyein Lee, Miram Shin, Min-Gi Shin, Jinsoo Seo, Eun Jeong Lee, Sun Ah Park, Soochul Park
Nat Commun. 2023; 14: 8463. Published online 2023 Dec 20. doi: 10.1038/s41467-023-44319-3
Correction in:
Nat Commun. 2024; 15: 3062.
PMCID:
PMC10733300
AbstractArticlePDF–6.2M
4.
Jun-APOE-LRP1 axis promotes tumor metastasis in colorectal cancer
Lingyuan He, Mengchen Shi, Shuwei Ren, Jingdan Zhang, Yu Tian, Xiangling Yang, Huanliang Liu
Biomol Biomed. 2023 Dec 1; 23(6): 1026–1037. Published online 2023 Dec 1. doi: 10.17305/bb.2023.9248
PMCID:
PMC10655886
AbstractArticlePDF–3.0M
5.
The endocytic receptor protein LRP-1 modulate P-glycoprotein mediated drug resistance in MCF-7 cells
Aubery Henry, Marine Mauperin, Jerome Devy, Stephane Dedieu, Lise Chazee, Cathy Hachet, Christine Terryn, Laurent Duca, Laurent Martiny, Emmanuelle Devarenne-Charpentier, Hassan El Btaouri
PLoS One. 2023; 18(9): e0285834. Published online 2023 Sep 28. doi: 10.1371/journal.pone.0285834
PMCID:
PMC10538702
AbstractArticlePDF–2.1M
6.
Exome-wide analysis reveals role of LRP1 and additional novel loci in cognition
Shreya Chakraborty, Bratati Kahali
HGG Adv. 2023 Jul 13; 4(3): 100208. Published online 2023 May 20. doi: 10.1016/j.xhgg.2023.100208
PMCID:
PMC10248556
AbstractArticlePDF–3.8M
7.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
8.
Peripheral apolipoprotein E proteins and their binding to LRP1 antagonize Alzheimer’s disease pathogenesis in the brain during peripheral chronic inflammation
Hana Na, Jack B. Yang, Zhengrong Zhang, Qini Gan, Hua Tian, Ibraheem M. Rajab, Lawrence A. Potempa, Qiushan Tao, Wei Qiao Qiu
Neurobiol Aging. Author manuscript; available in PMC 2024 Jul 1.
Published in final edited form as: Neurobiol Aging. 2023 Jul; 127: 54–69. Published online 2023 Mar 7. doi: 10.1016/j.neurobiolaging.2023.02.013
PMCID:
PMC10198819
AbstractArticlePDF–3.2M
9.
Contribution of LRP1 in Human Congenital Heart Disease Correlates with Its Roles in the Outflow Tract and Atrioventricular Cushion Development
Angelo B. Arrigo, Wenjuan Zhu, Kylia A. Williams, Carla Guzman-Moreno, Cecilia Lo, Jiuann-Huey I. Lin
Genes (Basel) 2023 Apr; 14(4): 947. Published online 2023 Apr 21. doi: 10.3390/genes14040947
PMCID:
PMC10137934
AbstractArticlePDF–31M
10.
LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4
Hiroshi Oue, Yu Yamazaki, Wenhui Qiao, Chen Yuanxin, Yingxue Ren, Aishe Kurti, Francis Shue, Tammee M. Parsons, Ralph B. Perkerson, Keiji Kawatani, Ni Wang, Skylar C. Starling, Bhaskar Roy, Ioana-Emilia Mosneag, Tomonori Aikawa, Marie-Louise Holm, Chia-Chen Liu, Yasuteru Inoue, Patrick M. Sullivan, Yan W. Asmann, Betty Y.S. Kim, Guojun Bu, Takahisa Kanekiyo
JCI Insight. 2023 Apr 10; 8(7): e163822. Published online 2023 Apr 10. doi: 10.1172/jci.insight.163822
PMCID:
PMC10132158
AbstractArticlePDF–1.4M
11.
Low-density lipoprotein receptor–related protein 1 (LRP1) as an auxiliary host factor for RNA viruses
Stephanie Devignot, Tim Wai Sha, Thomas R Burkard, Patrick Schmerer, Astrid Hagelkruys, Ali Mirazimi, Ulrich Elling, Josef M Penninger, Friedemann Weber
Life Sci Alliance. 2023 Jul; 6(7): e202302005. Published online 2023 Apr 18. doi: 10.26508/lsa.202302005
PMCID:
PMC10114362
AbstractArticlePDF–2.8M
12.
Serum Exosomes From Epithelial Ovarian Cancer Patients Contain LRP1, Which Promotes the Migration of Epithelial Ovarian Cancer Cell
Wei Zhou, Jiachen Ma, Han Zhao, Qing Wang, Xiaoli Guo, Linna Chen, Zhonghui Cao, Jiahao Xu, Bei Zhang, Xueyan Zhou
Mol Cell Proteomics. 2023 Apr; 22(4): 100520. Published online 2023 Feb 25. doi: 10.1016/j.mcpro.2023.100520
PMCID:
PMC10113894
AbstractArticlePDF–5.1M
13.
Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption
Lingxin Zhu, Yi Tang, Xiao-Yan Li, Samuel A. Kerk, Costas A. Lyssiotis, Xiaoyue Sun, Zijun Wang, Jung-Sun Cho, Jun Ma, Stephen J. Weiss
J Cell Biol. 2023 Apr 3; 222(4): e202206121. Published online 2023 Mar 2. doi: 10.1083/jcb.202206121
PMCID:
PMC9998966
AbstractArticlePDF–10M
14.
LRP-1 Links Post-Translational Modifications to Efficient Presentation of Celiac Disease-Specific T Cell Antigens
Elise Loppinet, Harrison A. Besser, Agnele Sylvia Sewa, Fu-Chen Yang, Bana Jabri, Chaitan Khosla
Cell Chem Biol. Author manuscript; available in PMC 2024 Jan 19.
Published in final edited form as: Cell Chem Biol. 2023 Jan 19; 30(1): 55–68.e10. Published online 2023 Jan 5. doi: 10.1016/j.chembiol.2022.12.002
PMCID:
PMC9868102
AbstractArticlePDF–3.5M
15.
Characterization of interaction between blood coagulation factor VIII and LRP1 suggests dynamic binding by alternating complex contacts
Haarin Chun, James H. Kurasawa, Philip Olivares, Ekaterina S. Marakasova, Svetlana A. Shestopal, Gabriela U. Hassink, Elena Karnaukhova, Mary Migliorini, Juliet O. Obi, Ally K. Smith, Patrick L. Wintrode, Prasannavenkatesh Durai, Keunwan Park, Daniel Deredge, Dudley K. Strickland, Andrey G. Sarafanov
J Thromb Haemost. 2022 Oct; 20(10): 2255–2269. Published online 2022 Aug 4. doi: 10.1111/jth.15817
PMCID:
PMC9804390
AbstractArticlePDF–16M
16.
MT1-MMP Expression Levels and Catalytic Functions Dictate LDL Receptor-Related Protein-1 Ligand Internalization Capacity in U87 Glioblastoma Cells
Jonathan Pratt, Khadidja Haidara, Borhane Annabi
Int J Mol Sci. 2022 Nov; 23(22): 14214. Published online 2022 Nov 17. doi: 10.3390/ijms232214214
PMCID:
PMC9692856
AbstractArticlePDF–2.5M
17.
Multitarget Activities of Müller Glial Cells and Low-Density Lipoprotein Receptor-Related Protein 1 in Proliferative Retinopathies
María C. Sanchez, Gustavo A. Chiabrando
ASN Neuro. 2022 Jan-Dec; 14: 17590914221136365. Published online 2022 Oct 31. doi: 10.1177/17590914221136365
PMCID:
PMC9629547
AbstractArticlePDF–1.4M
18.
Heterozygous LRP1 deficiency causes developmental dysplasia of the hip by impairing triradiate chondrocytes differentiation due to inhibition of autophagy
Wenjin Yan, Liming Zheng, Xingquan Xu, Zheng Hao, Yibo Zhang, Jun Lu, Ziying Sun, Jin Dai, Dongquan Shi, Baosheng Guo, Qing Jiang
Proc Natl Acad Sci U S A. 2022 Sep 13; 119(37): e2203557119. Published online 2022 Sep 6. doi: 10.1073/pnas.2203557119
PMCID:
PMC9477389
AbstractArticlePDF–2.9M
19.
LRP1 is a neuronal receptor for α-synuclein uptake and spread
Kai Chen, Yuka A. Martens, Axel Meneses, Daniel H. Ryu, Wenyan Lu, Ana Caroline Raulin, Fuyao Li, Jing Zhao, Yixing Chen, Yunjung Jin, Cynthia Linares, Marshall Goodwin, Yonghe Li, Chia-Chen Liu, Takahisa Kanekiyo, David M. Holtzman, Todd E. Golde, Guojun Bu, Na Zhao
Mol Neurodegener. 2022; 17: 57. Published online 2022 Sep 2. doi: 10.1186/s13024-022-00560-w
PMCID:
PMC9438229
AbstractArticlePDF–6.0M
20.
Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1
Madeline M. Schwarz, David A. Price, Safder S. Ganaie, Annie Feng, Nawneet Mishra, Ryan M. Hoehl, Farheen Fatma, Sarah H. Stubbs, Sean P. J. Whelan, Xiaoxia Cui, Takeshi Egawa, Daisy W. Leung, Gaya K. Amarasinghe, Amy L. Hartman
Proc Natl Acad Sci U S A. 2022 Aug 16; 119(33): e2204706119. Published online 2022 Aug 8. doi: 10.1073/pnas.2204706119
PMCID:
PMC9388146
AbstractArticlePDF–2.1M

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