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Items: 1 to 20 of 27

1.
Induction of zinc finger protein RNF6 auto-ubiquitination for the treatment of myeloma and chronic myeloid leukemia
Haixia Zhuang, Ying Ren, Chenyu Mao, Yueya Zhong, Zubin Zhang, Biyin Cao, Yuming Zhang, Jinqi Huang, Guoqiang Xu, Zhenqian Huang, Yujia Xu, Xinliang Mao
J Biol Chem. 2022 Sep; 298(9): 102314. Published online 2022 Aug 1. doi: 10.1016/j.jbc.2022.102314
PMCID:
PMC9436814
AbstractArticlePDF–3.8M
2.
Regulation of p27 (Kip1) by Ubiquitin E3 Ligase RNF6
Dhanraj Deshmukh, Jin Xu, Xi Yang, Hermela Shimelis, Shengyun Fang, Yun Qiu
Pharmaceutics. 2022 Apr; 14(4): 802. Published online 2022 Apr 6. doi: 10.3390/pharmaceutics14040802
PMCID:
PMC9029106
AbstractArticlePDF–3.0M
3.
RING-Finger Protein 6 promotes Drug Resistance in Retinoblastoma via JAK2/STAT3 Signaling Pathway
Yong Chai, Shoufeng Jiao, Xin Peng, Qiang Gan, Leifeng Chen, Xiaolu Hu, Liang Hao, Shouhua Zhang, Qiang Tao
Pathol Oncol Res. 2022; 28: 1610273. Published online 2022 Mar 18. doi: 10.3389/pore.2022.1610273
PMCID:
PMC8971205
AbstractArticlePDF–1.4M
4.
RNF6 promotes the migration and invasion of breast cancer by promoting the ubiquitination and degradation of MST1
Yajuan Huang, Yufeng Zou, Zhigang Jie
Exp Ther Med. 2022 Feb; 23(2): 118. Published online 2021 Dec 6. doi: 10.3892/etm.2021.11041
Correction in:
Exp Ther Med. 2022 May; 23(5): 326.
PMCID:
PMC8713179
AbstractArticlePDF–5.1M
5.
RING-finger protein 6 promotes colorectal tumorigenesis by transcriptionally activating SF3B2
Hui Xu, Chi Chun Wong, Weilin Li, Yunfei Zhou, Yan Li, Lifu Wang, Lei Liu, Jun Yu
Oncogene. 2021; 40(47): 6513–6526. Published online 2021 Oct 5. doi: 10.1038/s41388-021-01872-9
PMCID:
PMC8616760
AbstractArticlePDF–6.6M
6.
Knockdown of RNF6 inhibits HeLa cervical cancer cell growth via suppression of MAPK/ERK signaling
Kang Zhu, He Bai, Mingzhu Mu, Yuanyuan Xue, Zhao Duan
FEBS Open Bio. 2021 Jul; 11(7): 2041–2049. Published online 2021 Jun 18. doi: 10.1002/2211-5463.13216
PMCID:
PMC8255836
AbstractArticlePDF–3.0M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Rajat Gupta, Kumar Somyajit, Takeo Narita, Elina Maskey, Andre Stanlie, Magdalena Kremer, Dimitris Typas, Michael Lammers, Niels Mailand, Andre Nussenzweig, Jiri Lukas, Chunaram Choudhary
Cell. Author manuscript; available in PMC 2021 May 10.
Published in final edited form as: Cell. 2018 May 3; 173(4): 972–988.e23. Published online 2018 Apr 12. doi: 10.1016/j.cell.2018.03.050
PMCID:
PMC8108093
AbstractArticlePDF–3.5M
9.
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination
Ying Ren, Xin Xu, Chen-yu Mao, Kun-kun Han, Yu-jia Xu, Bi-yin Cao, Zu-bin Zhang, Gautam Sethi, Xiao-wen Tang, Xin-liang Mao
Acta Pharmacol Sin. 2020 Mar; 41(3): 394–403. Published online 2019 Oct 23. doi: 10.1038/s41401-019-0309-6
PMCID:
PMC7470801
AbstractArticlePDF–2.7M
10.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
11.
Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers
Joseph Rosenbluh, Johnathan Mercer, Yashaswi Shrestha, Rachel Oliver, Pablo Tamayo, John G. Doench, Itay Tirosh, Federica Piccioni, Ella Hartenian, Heiko Horn, Lola Fagbami, David E. Root, Jacob Jaffe, Kasper Lage, Jesse S. Boehm, William C. Hahn
Cell Syst. Author manuscript; available in PMC 2017 Sep 28.
Published in final edited form as: Cell Syst. 2016 Sep 28; 3(3): 302–316.e4. doi: 10.1016/j.cels.2016.09.001
PMCID:
PMC5455996
AbstractArticlePDF–3.1M
12.
Ring finger protein 6 promotes breast cancer cell proliferation by stabilizing estrogen receptor alpha
Yuanying Zeng, Xin Xu, Siyu Wang, Zubin Zhang, Yan Liu, Kunkun Han, Biyin Cao, Xinliang Mao
Oncotarget. 2017 Mar 21; 8(12): 20103–20112. Published online 2017 Feb 16. doi: 10.18632/oncotarget.15384
PMCID:
PMC5386747
AbstractArticlePDF–4.1M
13.
Establishment of a Wheat Cell-Free Synthesized Protein Array Containing 250 Human and Mouse E3 Ubiquitin Ligases to Identify Novel Interaction between E3 Ligases and Substrate Proteins
Hirotaka Takahashi, Atsushi Uematsu, Satoshi Yamanaka, Mei Imamura, Tatsuro Nakajima, Kousuke Doi, Saki Yasuoka, Chikako Takahashi, Hiroyuki Takeda, Tatsuya Sawasaki
PLoS One. 2016; 11(6): e0156718. Published online 2016 Jun 1. doi: 10.1371/journal.pone.0156718
PMCID:
PMC4889105
AbstractArticlePDF–3.3M
14.
Widespread expansion of protein interaction capabilities by alternative splicing
Xinping Yang, Jasmin Coulombe-Huntington, Shuli Kang, Gloria M. Sheynkman, Tong Hao, Aaron Richardson, Song Sun, Fan Yang, Yun A. Shen, Ryan R. Murray, Kerstin Spirohn, Bridget E. Begg, Miquel Duran-Frigola, Andrew MacWilliams, Samuel J. Pevzner, Quan Zhong, Shelly A. Wanamaker, Stanley Tam, Lila Ghamsari, Nidhi Sahni, Song Yi, Maria D. Rodriguez, Dawit Balcha, Guihong Tan, Michael Costanzo, Brenda Andrews, Charles Boone, Xianghong J. Zhou, Kourosh Salehi-Ashtiani, Benoit Charloteaux, Alyce A. Chen, Michael A. Calderwood, Patrick Aloy, Frederick P. Roth, David E. Hill, Lilia M. Iakoucheva, Yu Xia, Marc Vidal
Cell. Author manuscript; available in PMC 2017 Feb 11.
Published in final edited form as: Cell. 2016 Feb 11; 164(4): 805–817. doi: 10.1016/j.cell.2016.01.029
PMCID:
PMC4882190
AbstractArticlePDF–1.9M
15.
The Ring Finger Protein RNF6 Induces Leukemia Cell Proliferation as a Direct Target of Pre-B-cell Leukemia Homeobox 1
Xin Xu, Kunkun Han, Xiaowen Tang, Yuanying Zeng, Xu Lin, Yun Zhao, Zubin Zhang, Biyin Cao, Depei Wu, Xinliang Mao
J Biol Chem. 2016 Apr 29; 291(18): 9617–9628. Published online 2016 Mar 12. doi: 10.1074/jbc.M115.701979
PMCID:
PMC4850299
AbstractArticlePDF–2.1M
16.
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium, South Asian Type 2 Diabetes (SAT2D) Consortium, Mexican American Type 2 Diabetes (MAT2D) Consortium, Type 2 Diabetes Genetic Exploration by Next-generation sequencing in multi-Ethnic Samples (T2D-GENES) Consortium
Nat Genet. Author manuscript; available in PMC 2014 Sep 1.
Published in final edited form as: Nat Genet. 2014 Mar; 46(3): 234–244. Published online 2014 Feb 9. doi: 10.1038/ng.2897
PMCID:
PMC3969612
AbstractArticlePDF–725K
17.
A Comprehensive Genetic Association Study of Alzheimer Disease in African Americans
Dr. Mark W. Logue, Messr. Matthew Schu, Messr. Badri N. Vardarajan, Ms Jacki Buros, Dr. Robert C. Green, Dr. Rodney C. P. Go, Dr. Patrick Griffith, Dr. Thomas O. Obisesan, Dr. Rhonna Shatz, Dr. Amy Borenstein, Dr. L. Adrienne Cupples, Dr. Kathryn L. Lunetta, Dr. M. Daniele Fallin, Dr. Clinton T. Baldwin, Dr. Lindsay A. Farrer
Arch Neurol. Author manuscript; available in PMC 2012 May 21.
Published in final edited form as: Arch Neurol. 2011 Dec; 68(12): 1569–1579. doi: 10.1001/archneurol.2011.646
PMCID:
PMC3356921
AbstractArticlePDF–1.4M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination
Kexin Xu, Hermela Shimelis, Douglas E. Linn, Richeng Jiang, Xi Yang, Feng Sun, Zhiyong Guo, Hege Chen, Wei Li, Hegang Chen, Xiangtian Kong, Jonathan Melamed, Shengyun Fang, Zhen Xiao, Timothy D. Veenstra, Yun Qiu
Cancer Cell. Author manuscript; available in PMC 2010 Apr 7.
Published in final edited form as: Cancer Cell. 2009 Apr 7; 15(4): 270–282. doi: 10.1016/j.ccr.2009.02.021
PMCID:
PMC2848969
AbstractArticlePDF–2.6M
20.
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network
Gabriel Markson, Christina Kiel, Russell Hyde, Stephanie Brown, Panagoula Charalabous, Anja Bremm, Jennifer Semple, Jonathan Woodsmith, Simon Duley, Kourosh Salehi-Ashtiani, Marc Vidal, David Komander, Luis Serrano, Paul Lehner, Christopher M. Sanderson
Genome Res. 2009 Oct; 19(10): 1905–1911. doi: 10.1101/gr.093963.109
PMCID:
PMC2765280
AbstractArticlePDF–425K

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