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Items: 1 to 20 of 52

1.
Interleukin-1 receptor accessory protein blockade limits the development of atherosclerosis and reduces plaque inflammation
Megan Mulholland, Marie A C Depuydt, Gabriel Jakobsson, Irena Ljungcrantz, Andrietta Grentzmann, Fong To, Eva Bengtsson, Elin Jaensson Gyllenbäck, Caitríona Grönberg, Sara Rattik, David Liberg, Alexandru Schiopu, Harry Björkbacka, Johan Kuiper, Ilze Bot, Bram Slütter, Daniel Engelbertsen
Cardiovasc Res. 2024 Apr; 120(6): 581–595. Published online 2024 Apr 2. doi: 10.1093/cvr/cvae046
PMCID:
PMC11074796
AbstractArticlePDF–4.6M
2.
Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma
Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn
Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255
PMCID:
PMC10916866
AbstractArticlePDF–4.7M
3.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
4.
IL1RAP expression and the enrichment of IL‐33 activation signatures in severe neutrophilic asthma
Yusef Eamon Badi, Barbora Salcman, Adam Taylor, Batika Rana, Nazanin Zounemat Kermani, John H. Riley, Sally Worsley, Sharon Mumby, Sven‐Eric Dahlen, David Cousins, Silvia Bulfone‐Paus, Karen Affleck, Kian Fan Chung, Stewart Bates, Ian M. Adcock
Allergy. 2023 Jan; 78(1): 156–167. Published online 2022 Aug 28. doi: 10.1111/all.15487
PMCID:
PMC10086999
AbstractArticlePDF–9.3M
5.
IL1RAP is expressed in several subtypes of pediatric acute lymphoblastic leukemia and can be used as a target to eliminate ETV6::RUNX1-positive leukemia cells in preclinical models
Helena Ågerstam, Henrik Lilljebjörn, Marianne Rissler, Carl Sandén1, Thoas Fioretos
Haematologica. 2023 Feb 1; 108(2): 599–604. Published online 2022 Oct 13. doi: 10.3324/haematol.2022.281059
PMCID:
PMC9890010
ArticlePDF–1.0M
6.
Chimeric antigen receptor T-cells targeting IL-1RAP: a promising new cellular immunotherapy to treat acute myeloid leukemia
Rim Trad, Walid Warda, Vincent Alcazer, Mathieu Neto da Rocha, Ana Berceanu, Clémentine Nicod, Rafik Haderbache, Xavier Roussel, Yohan Desbrosses, Etienne Daguindau, Florain Renosi, Christophe Roumier, Lucie Bouquet, Sabeha Biichle, Melanie Guiot, Evan Seffar, Denis Caillot, Stephane Depil, Eric Robinet, Yahya Salma, Eric Deconinck, Marina Deschamps, Christophe Ferrand
J Immunother Cancer. 2022; 10(7): e004222. Published online 2022 Jul 8. doi: 10.1136/jitc-2021-004222
PMCID:
PMC9272123
AbstractArticlePDF–7.4M
7.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
8.
Innate immune mediator, Interleukin-1 receptor accessory protein (IL1RAP), is expressed and pro-tumorigenic in pancreatic cancer
Yang Zhang, Xiaoyi Chen, Huamin Wang, Shanisha Gordon-Mitchell, Srabani Sahu, Tushar D. Bhagat, Gaurav Choudhary, Srinivas Aluri, Kith Pradhan, Plabani Sahu, Milagros Carbajal, Hui Zhang, Beamon Agarwal, Aditi Shastri, Robert Martell, Daniel Starczynowski, Ulrich Steidl, Anirban Maitra, Amit Verma
J Hematol Oncol. 2022; 15: 70. Published online 2022 May 23. doi: 10.1186/s13045-022-01286-4
Correction in:
J Hematol Oncol. 2022; 15: 100.
PMCID:
PMC9128118
AbstractArticlePDF–3.6M
9.
Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma
Hai-Feng Zhang, Christopher S. Hughes, Wei Li, Jian-Zhong He, Didier Surdez, Amal M. El-Naggar, Hongwei Cheng, Anna Prudova, Alberto Delaidelli, Gian Luca Negri, Xiaojun Li, Maj Sofie Ørum-Madsen, Michael M. Lizardo, Htoo Zarni Oo, Shane Colborne, Taras Shyp, Renata Scopim-Ribeiro, Colin A. Hammond, Anne-Chloe Dhez, Sofya Langman, Jonathan K.M. Lim, Sonia H.Y. Kung, Amy Li, Anne Steino, Mads Daugaard, Seth J. Parker, Ramon I. Klein Geltink, Rimas J. Orentas, Li-Yan Xu, Gregg B. Morin, Olivier Delattre, Dimiter S. Dimitrov, Poul H. Sorensen
Cancer Discov. 2021 Nov 1; 11(11): 2884–2903. Published online 2021 May 25. doi: 10.1158/2159-8290.CD-20-1690
PMCID:
PMC8563374
AbstractArticlePDF–8.9M
10.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
11.
The Potential Role of IL1RAP on Tumor Microenvironment-Related Inflammatory Factors in Stomach Adenocarcinoma
Qing Lv, Qinghua Xia, Anshu Li, Zhiyong Wang
Technol Cancer Res Treat. 2021; 20: 1533033821995282. Published online 2021 Feb 19. doi: 10.1177/1533033821995282
PMCID:
PMC7897808
AbstractArticlePDF–1.6M
12.
The Role of SNPs in IL1RL1 and IL1RAP Genes in Age-related Macular Degeneration Development and Treatment Efficacy
ALVITA VILKEVICIUTE, NERINGA BASTIKAITYTE, RUTA MOCKUTE, DZASTINA CEBATORIENE, LORESA KRIAUCIUNIENE, JURATE BALCIUNIENE, REDA ZEMAITIENE, RASA LIUTKEVICIENE
In Vivo. 2020 Sep-Oct; 34(5): 2443–2451. Published online 2020 Sep 3. doi: 10.21873/invivo.12059
PMCID:
PMC7652449
AbstractArticlePDF–155K
13.
IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease
Jesper Falkesgaard Højen, Marie Louise Vindvad Kristensen, Amy S. McKee, Megan Taylor Wade, Tania Azam, Lars P. Lunding, Dennis M. de Graaf, Benjamin J. Swartzwelter, Michael Wegmann, Martin Tolstrup, Karsten Beckman, Mayumi Fujita, Stephan Fischer, Charles A. Dinarello
Nat Immunol. Author manuscript; available in PMC 2020 Feb 19.
Published in final edited form as: Nat Immunol. 2019 Sep; 20(9): 1138–1149. Published online 2019 Aug 19. doi: 10.1038/s41590-019-0467-1
PMCID:
PMC6707854
AbstractArticlePDF–1.7M
14.
Interleukin-1 Receptor Accessory Protein Organizes Neuronal Synaptogenesis as a Cell Adhesion Molecule
Tomoyuki Yoshida, Tomoko Shiroshima, Sung-Jin Lee, Misato Yasumura, Takeshi Uemura, Xigui Chen, Yoichiro Iwakura, Masayoshi Mishina
J Neurosci. 2012 Feb 22; 32(8): 2588–2600. doi: 10.1523/JNEUROSCI.4637-11.2012
PMCID:
PMC6621890
AbstractArticlePDF–5.2M
15.
Association of IL1RAP-related genetic variation with cerebrospinal fluid concentration of Alzheimer-associated tau protein
Anna Zettergren, Kina Höglund, Silke Kern, Valgeir Thorvaldsson, Msc Johan Skoog, Oskar Hansson, Niels Andreasen, Nenad Bogdanovic, Kaj Blennow, Ingmar Skoog, Henrik Zetterberg
Sci Rep. 2019; 9: 2460. Published online 2019 Feb 21. doi: 10.1038/s41598-018-36650-3
PMCID:
PMC6385252
AbstractArticlePDF–1.0M
16.
Potential regulatory network in the PSG10P/miR‐19a‐3p/IL1RAP pathway is possibly involved in preeclampsia pathogenesis
Nan Wang, Ruizhen Li, Min Xue
J Cell Mol Med. 2019 Feb; 23(2): 852–864. Published online 2018 Oct 28. doi: 10.1111/jcmm.13985
PMCID:
PMC6349174
AbstractArticlePDF–2.4M
17.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
18.
IL1RAP potentiates multiple oncogenic signaling pathways in AML
Kelly Mitchell, Laura Barreyro, Tihomira I. Todorova, Samuel J. Taylor, Iléana Antony-Debré, Swathi-Rao Narayanagari, Luis A. Carvajal, Joana Leite, Zubair Piperdi, Gopichand Pendurti, Ioannis Mantzaris, Elisabeth Paietta, Amit Verma, Kira Gritsman, Ulrich Steidl
J Exp Med. 2018 Jun 4; 215(6): 1709–1727. doi: 10.1084/jem.20180147
PMCID:
PMC5987926
AbstractArticlePDF–2.6M
19.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
20.
Structural and Functional Attributes of the Interleukin-36 Receptor
Guanghui Yi, Joel A. Ybe, Siddhartha S. Saha, Gary Caviness, Ernest Raymond, Rajkumar Ganesan, M. Lamine Mbow, C. Cheng Kao
J Biol Chem. 2016 Aug 5; 291(32): 16597–16609. Published online 2016 Jun 15. doi: 10.1074/jbc.M116.723064
PMCID:
PMC4974375
AbstractArticlePDF–3.5M

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