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Items: 1 to 20 of 23

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Dysregulated ceramides metabolism by fatty acid 2-hydroxylase exposes a metabolic vulnerability to target cancer metastasis
Xuantong Zhou, Furong Huang, Gang Ma, Wenqing Wei, Nan Wu, Zhihua Liu
Signal Transduct Target Ther. 2022; 7: 370. Published online 2022 Oct 24. doi: 10.1038/s41392-022-01199-1
PMCID:
PMC9588768
AbstractArticlePDF–7.6M
3.
Age-Dependent Increase in Schmidt-Lanterman Incisures and a Cadm4-Associated Membrane Skeletal Complex in Fatty Acid 2-hydroxylase Deficient Mice: a Mouse Model of Spastic Paraplegia SPG35
Silvia Jordans, Robert Hardt, Ivonne Becker, Dominic Winter, Lihua Wang-Eckhardt, Matthias Eckhardt
Mol Neurobiol. 2022; 59(7): 3969–3979. Published online 2022 Apr 20. doi: 10.1007/s12035-022-02832-4
PMCID:
PMC9167166
AbstractArticlePDF–4.8M
4.
Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075
Yudong Ji, Zhenlong Luo, Hong Gao, Felipe Castellani Gomes Dos Reis, Gautam Bandyopadhyay, Zhongmou Jin, Kameswari Ananthakrishnan Manda, Roi Isaac, Meixiang Yang, Wenxian Fu, Wei Ying, Jerrold M. Olefsky
Nat Metab. Author manuscript; available in PMC 2022 Mar 6.
Published in final edited form as: Nat Metab. 2021 Sep; 3(9): 1163–1174. Published online 2021 Sep 6. doi: 10.1038/s42255-021-00444-1
PMCID:
PMC8460610
AbstractArticlePDF–2.8M
5.
ACAA2 is a Ligand-dependent Coactivator for Thyroid Hormone Receptor β1
Wesley Wang, Dolena Ledee
Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Oct 22.
Published in final edited form as: Biochem Biophys Res Commun. 2021 Oct 22; 576: 15–21. Published online 2021 Aug 28. doi: 10.1016/j.bbrc.2021.08.073
PMCID:
PMC8446338
AbstractArticlePDF–830K
6.
Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation
Miriam Wedel, Franziska Fröb, Olga Elsesser, Marie-Theres Wittmann, D Chichung Lie, André Reis, Michael Wegner
Nucleic Acids Res. 2020 May 21; 48(9): 4839–4857. Published online 2020 Apr 8. doi: 10.1093/nar/gkaa218
PMCID:
PMC7229849
AbstractArticlePDF–36M
7.
Absence of 2-Hydroxylated Sphingolipids Is Compatible with Normal Neural Development But Causes Late-Onset Axon and Myelin Sheath Degeneration
Inge Zöller, Marion Meixner, Dieter Hartmann, Heinrich Büssow, Rainer Meyer, Volkmar Gieselmann, Matthias Eckhardt
J Neurosci. 2008 Sep 24; 28(39): 9741–9754. doi: 10.1523/JNEUROSCI.0458-08.2008
PMCID:
PMC6671223
AbstractArticlePDF–1.2M
8.
Elovl4 and Fa2h expression during rat spermatogenesis: a link to the very-long-chain PUFAs typical of germ cell sphingolipids
Florencia X. Santiago Valtierra, Daniel A. Peñalva, Jessica M. Luquez, Natalia E. Furland, Claudia Vásquez, Juan G. Reyes, Marta I. Aveldaño, Gerardo M. Oresti
J Lipid Res. 2018 Jul; 59(7): 1175–1189. Published online 2018 May 3. doi: 10.1194/jlr.M081885
PMCID:
PMC6027906
AbstractArticlePDF–2.3M
9.
Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function
Andrew J. Kennedy, Elizabeth J. Rahn, Brynna S. Paulukaitis, Katherine E. Savell, Holly B. Kordasiewicz, Jing Wang, John W. Lewis, Jessica Posey, Sarah K. Strange, Mikael C. Guzman-Karlsson, Scott E. Phillips, Kyle Decker, S. Timothy Motley, Eric E. Swayze, David J. Ecker, Todd P. Michael, Jeremy J. Day, J. David Sweatt
Cell Rep. Author manuscript; available in PMC 2017 Dec 1.
Published in final edited form as: Cell Rep. 2016 Sep 6; 16(10): 2666–2685. Published online 2016 Aug 25. doi: 10.1016/j.celrep.2016.08.004
PMCID:
PMC5710002
AbstractArticlePDF–1.4M
10.
Diastereomer-specific quantification of bioactive hexosylceramides from bacteria and mammals
Johanna von Gerichten, Kerstin Schlosser, Dominic Lamprecht, Ivan Morace, Matthias Eckhardt, Dagmar Wachten, Richard Jennemann, Hermann-Josef Gröne, Matthias Mack, Roger Sandhoff
J Lipid Res. 2017 Jun; 58(6): 1247–1258. Published online 2017 Apr 3. doi: 10.1194/jlr.D076190
PMCID:
PMC5454501
AbstractArticlePDF–1.4M
11.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
12.
Stereospecificity of fatty acid 2-hydroxylase and differential functions of 2-hydroxy fatty acid enantiomers
Lin Guo, Xu Zhang, Dequan Zhou, Adewole L. Okunade, Xiong Su
J Lipid Res. 2012 Jul; 53(7): 1327–1335. doi: 10.1194/jlr.M025742
PMCID:
PMC3371244
AbstractArticlePDF–880K
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
Normal Fur Development and Sebum Production Depends on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands
Helena Maier, Marion Meixner, Dieter Hartmann, Roger Sandhoff, Lihua Wang-Eckhardt, Inge Zöller, Volkmar Gieselmann, Matthias Eckhardt
J Biol Chem. 2011 Jul 22; 286(29): 25922–25934. Published online 2011 May 31. doi: 10.1074/jbc.M111.231977
PMCID:
PMC3138264
AbstractArticlePDF–6.6M
15.
Central nervous system dysfunction in a mouse model of FA2H deficiency
Kathleen A. Potter, Michael J. Kern, George Fullbright, Jacek Bielawski, Steven S. Scherer, Sabrina W. Yum, Jian J. Li, Hua Cheng, Xianlin Han, Jagadish Kummetha Venkata, P. Akbar Ali Khan, Bärbel Rohrer, Hiroko Hama
Glia. Author manuscript; available in PMC 2012 Jul 1.
Published in final edited form as: Glia. 2011 Jul; 59(7): 1009–1021. Published online 2011 Apr 13. doi: 10.1002/glia.21172
PMCID:
PMC3094470
AbstractArticlePDF–1.5M
16.
Myelination in the absence of UDP-galactose:ceramide galactosyl-transferase and fatty acid 2 -hydroxylase
Marion Meixner, Julia Jungnickel, Claudia Grothe, Volkmar Gieselmann, Matthias Eckhardt
BMC Neurosci. 2011; 12: 22. Published online 2011 Mar 2. doi: 10.1186/1471-2202-12-22
PMCID:
PMC3053264
AbstractArticlePDF–778K
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
Fatty Acid 2-Hydroxylase Mediates Diffusional Mobility of Raft-associated Lipids, GLUT4 Level, and Lipogenesis in 3T3-L1 Adipocytes
Lin Guo, Dequan Zhou, Kenneth M. Pryse, Adewole L. Okunade, Xiong Su
J Biol Chem. 2010 Aug 13; 285(33): 25438–25447. Published online 2010 Jun 2. doi: 10.1074/jbc.M110.119933
PMCID:
PMC2919107
AbstractArticlePDF–1.4M
19.
A mammalian fatty acid hydroxylase responsible for the formation of α-hydroxylated galactosylceramide in myelin
Matthias Eckhardt, Afshin Yaghootfam, Simon N. Fewou, Inge Zöller, Volkmar Gieselmann
Biochem J. 2005 May 15; 388(Pt 1): 245–254. Prepublished online 2005 Jan 20. Published online 2005 May 10. doi: 10.1042/BJ20041451
PMCID:
PMC1186713
AbstractArticlePDF–857K
20.
Construction of Long-Transcript Enriched cDNA Libraries from Submicrogram Amounts of Total RNAs by a Universal PCR Amplification Method
Yulan Piao, Naomi T. Ko, Meng K. Lim, Minoru S.H. Ko
Genome Res. 2001 Sep; 11(9): 1553–1558. doi: 10.1101/gr.185501
PMCID:
PMC311119
AbstractArticlePDF–743K

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