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Items: 1 to 20 of 27

1.
The RabGEF ALS2 is a hypoxia inducible target associated with the acquisition of aggressive traits in tumor cells
Solange Rivas, Patricio Silva, Montserrat Reyes, Hugo Sepúlveda, Luis Solano, Juan Acuña, Marisol Guerrero, Manuel Varas-Godoy, Andrew F. G. Quest, Martín Montecino, Vicente A. Torres
Sci Rep. 2020; 10: 22302. Published online 2020 Dec 18. doi: 10.1038/s41598-020-79270-6
PMCID:
PMC7749157
AbstractArticlePDF–2.4M
2.
Absence of alsin function leads to corticospinal motor neuron vulnerability via novel disease mechanisms
Mukesh Gautam, Javier H. Jara, Gabriella Sekerkova, Marina V. Yasvoina, Marco Martina, P. Hande Özdinler
Hum Mol Genet. 2016 Mar 15; 25(6): 1074–1087. Published online 2016 Jan 10. doi: 10.1093/hmg/ddv631
PMCID:
PMC4764190
AbstractArticlePDF–2.4M
3.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
4.
Different Human Copper-Zinc Superoxide Dismutase Mutants, SOD1G93A and SOD1H46R, Exert Distinct Harmful Effects on Gross Phenotype in Mice
Lei Pan, Yasuhiro Yoshii, Asako Otomo, Haruko Ogawa, Yasuo Iwasaki, Hui-Fang Shang, Shinji Hadano
PLoS One. 2012; 7(3): e33409. Published online 2012 Mar 16. doi: 10.1371/journal.pone.0033409
PMCID:
PMC3306410
AbstractArticlePDF–801K
5.
Alsin and SOD1G93A Proteins Regulate Endosomal Reactive Oxygen Species Production by Glial Cells and Proinflammatory Pathways Responsible for Neurotoxicity
Qiang Li, Netanya Y. Spencer, Nicholas J. Pantazis, John F. Engelhardt
J Biol Chem. 2011 Nov 18; 286(46): 40151–40162. Published online 2011 Sep 20. doi: 10.1074/jbc.M111.279711
PMCID:
PMC3220533
AbstractArticlePDF–3.1M
6.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
7.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
8.
Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1H46R-Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking
Shinji Hadano, Asako Otomo, Ryota Kunita, Kyoko Suzuki-Utsunomiya, Akira Akatsuka, Masato Koike, Masashi Aoki, Yasuo Uchiyama, Yasuto Itoyama, Joh-E Ikeda
PLoS One. 2010; 5(3): e9805. Published online 2010 Mar 22. doi: 10.1371/journal.pone.0009805
PMCID:
PMC2842444
AbstractArticlePDF–8.9M
9.
Regulation of endosomal motility and degradation by amyotrophic lateral sclerosis 2/alsin
Chen Lai, Chengsong Xie, Hoon Shim, Jayanth Chandran, Brian W Howell, Huaibin Cai
Mol Brain. 2009; 2: 23. Published online 2009 Jul 24. doi: 10.1186/1756-6606-2-23
PMCID:
PMC2724476
AbstractArticlePDF–2.3M
10.
Amyotrophic Lateral Sclerosis 2-Deficiency Leads to Neuronal Degeneration in Amyotrophic Lateral Sclerosis through Altered AMPA Receptor Trafficking
Chen Lai, Chengsong Xie, Stefanie G. McCormack, Hsueh-Cheng Chiang, Marta K. Michalak, Xian Lin, Jayanth Chandran, Hoon Shim, Mika Shimoji, Mark R. Cookson, Richard L. Huganir, Jeffrey D. Rothstein, Donald L. Price, Philip C. Wong, Lee J. Martin, J. Julius Zhu, Huaibin Cai
J Neurosci. 2006 Nov 8; 26(45): 11798–11806. doi: 10.1523/JNEUROSCI.2084-06.2006
PMCID:
PMC2556290
AbstractArticlePDF–672K
11.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
12.
Deficiency in the ALS2 gene does not affect the motor neuron degeneration in SOD1G93A transgenic mice
Xian Lin, Hoon Shim, Huaibin Cai
Neurobiol Aging. Author manuscript; available in PMC 2008 Jun 9.
Published in final edited form as: Neurobiol Aging. 2007 Oct; 28(10): 1628–1630. Published online 2006 Sep 12. doi: 10.1016/j.neurobiolaging.2006.07.014
PMCID:
PMC2423343
AbstractArticlePDF–401K
13.
Loss of ALS2 Function Is Insufficient to Trigger Motor Neuron Degeneration in Knock-Out Mice But Predisposes Neurons to Oxidative Stress
Huaibin Cai, Xian Lin, Chengsong Xie, Fiona M. Laird, Chen Lai, Hongjin Wen, Hsueh-Cheng Chiang, Hoon Shim, Mohamed H. Farah, Ahmet Hoke, Donald L. Price, Philip C. Wong
J Neurosci. 2005 Aug 17; 25(33): 7567–7574. doi: 10.1523/JNEUROSCI.1645-05.2005
PMCID:
PMC2364727
AbstractArticlePDF–558K
14.
Alsin and the Molecular Pathways of Amyotrophic Lateral Sclerosis
Jayanth Chandran, Jinhui Ding, Huaibin Cai
Mol Neurobiol. Author manuscript; available in PMC 2008 May 2.
Published in final edited form as: Mol Neurobiol. 2007 Dec; 36(3): 224–231. Published online 2007 Jul 10. doi: 10.1007/s12035-007-0034-x
PMCID:
PMC2364715
AbstractArticlePDF–469K
15.
Mice deficient in the ALS2 gene exhibit lymphopenia and abnormal hematopietic function
Elizabeth A. Erie, Hoon Shim, Aleah L. Smith, Xian Lin, Keyvan Keyvanfar, Chengsong Xie, Jichun Chen, Huaibin Cai
J Neuroimmunol. Author manuscript; available in PMC 2007 Feb 9.
Published in final edited form as: J Neuroimmunol. 2007 Jan; 182(1-2): 226–231. Published online 2006 Dec 6. doi: 10.1016/j.jneuroim.2006.10.019
PMCID:
PMC1796843
AbstractArticlePDF–644K
16.
Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo
Alexei V. Evsikov, Joel H. Graber, J. Michael Brockman, Aleš Hampl, Andrea E. Holbrook, Priyam Singh, John J. Eppig, Davor Solter, Barbara B. Knowles
Genes Dev. 2006 Oct 1; 20(19): 2713–2727. doi: 10.1101/gad.1471006
PMCID:
PMC1578697
AbstractArticlePDF–1.7M
17.
Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities
R. S. Devon, P. C. Orban, K. Gerrow, M. A. Barbieri, C. Schwab, L. P. Cao, J. R. Helm, N. Bissada, R. Cruz-Aguado, T.-L. Davidson, J. Witmer, M. Metzler, C. K. Lam, W. Tetzlaff, E. M. Simpson, J. M. McCaffery, A. E. El-Husseini, B. R. Leavitt, M. R. Hayden
Proc Natl Acad Sci U S A. 2006 Jun 20; 103(25): 9595–9600. Published online 2006 Jun 12. doi: 10.1073/pnas.0510197103
PMCID:
PMC1480452
AbstractArticlePDF–1.1M
18.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K
19.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
20.
Construction of Long-Transcript Enriched cDNA Libraries from Submicrogram Amounts of Total RNAs by a Universal PCR Amplification Method
Yulan Piao, Naomi T. Ko, Meng K. Lim, Minoru S.H. Ko
Genome Res. 2001 Sep; 11(9): 1553–1558. doi: 10.1101/gr.185501
PMCID:
PMC311119
AbstractArticlePDF–743K

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