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Items: 1 to 20 of 29

1.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
2.
Interferon-Inducible GTPase 1 Impedes the Dimerization of Rabies Virus Phosphoprotein and Restricts Viral Replication
Bin Tian, Yueming Yuan, Yu Yang, Zhaochen Luo, Baokun Sui, Ming Zhou, Zhen F. Fu, Ling Zhao
J Virol. 2020 Nov; 94(21): e01203-20. Prepublished online 2020 Aug 12. Published online 2020 Oct 14. doi: 10.1128/JVI.01203-20
PMCID:
PMC7565619
AbstractArticlePDF–3.6M
3.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
4.
The Toxoplasma gondii rhoptry protein ROP18 is an Irga6‐specific kinase and regulated by the dense granule protein GRA7
Thomas Hermanns, Urs B. Müller, Stephanie Könen‐Waisman, Jonathan C. Howard, Tobias Steinfeldt
Cell Microbiol. 2016 Feb; 18(2): 244–259. Published online 2015 Oct 30. doi: 10.1111/cmi.12499
PMCID:
PMC5061101
AbstractArticlePDF–1.4M
5.
The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashion
Kathrin Schulte, Nikolaus Pawlowski, Katja Faelber, Chris Fröhlich, Jonathan Howard, Oliver Daumke
BMC Biol. 2016; 14: 14. Published online 2016 Mar 2. doi: 10.1186/s12915-016-0236-7
PMCID:
PMC4774019
AbstractArticlePDF–1.7M
6.
Identification of the Microsporidian Encephalitozoon cuniculi as a New Target of the IFNγ-Inducible IRG Resistance System
Marialice da Fonseca Ferreira-da-Silva, Helen Maria Springer-Frauenhoff, Wolfgang Bohne, Jonathan C. Howard
PLoS Pathog. 2014 Oct; 10(10): e1004449. Published online 2014 Oct 30. doi: 10.1371/journal.ppat.1004449
Correction in:
PLoS Pathog. 2014 Dec; 10(12): e1004590.
PMCID:
PMC4214799
AbstractArticlePDF–2.0M
7.
The Toxoplasma Pseudokinase ROP5 Is an Allosteric Inhibitor of the Immunity-related GTPases
Michael L. Reese, Niket Shah, John C. Boothroyd
J Biol Chem. 2014 Oct 3; 289(40): 27849–27858. Published online 2014 Aug 12. doi: 10.1074/jbc.M114.567057
PMCID:
PMC4183819
AbstractArticlePDF–3.9M
8.
Impact of lactobacilli on orally acquired listeriosis
Cristel Archambaud, Marie-Anne Nahori, Guillaume Soubigou, Christophe Bécavin, Laure Laval, Pierre Lechat, Tamara Smokvina, Philippe Langella, Marc Lecuit, Pascale Cossart
Proc Natl Acad Sci U S A. 2012 Oct 9; 109(41): 16684–16689. Published online 2012 Sep 24. doi: 10.1073/pnas.1212809109
PMCID:
PMC3478606
AbstractArticlePDF–772K
9.
A Toxoplasma gondii Pseudokinase Inhibits Host IRG Resistance Proteins
Martin C. Fleckenstein, Michael L. Reese, Stephanie Könen-Waisman, John C. Boothroyd, Jonathan C. Howard, Tobias Steinfeldt
PLoS Biol. 2012 Jul; 10(7): e1001358. Published online 2012 Jul 10. doi: 10.1371/journal.pbio.1001358
PMCID:
PMC3393671
AbstractArticlePDF–2.1M
10.
Gene expression profiling at early organogenesis reveals both common and diverse mechanisms in foregut patterning
Henrik Fagman, Elena Amendola, Luca Parrillo, Pietro Zoppoli, Pina Marotta, Marzia Scarfò, Pasquale De Luca, Denise Pires de Carvalho, Michele Ceccarelli, Mario De Felice, Roberto Di Lauro
Dev Biol. 2011 Nov 15; 359(2): 163–175. doi: 10.1016/j.ydbio.2011.08.015
PMCID:
PMC3206993
AbstractArticle
11.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
12.
Immunity-related GTPase M (IRGM) Proteins Influence the Localization of Guanylate-binding Protein 2 (GBP2) by Modulating Macroautophagy
Maria K. Traver, Stanley C. Henry, Viviana Cantillana, Tim Oliver, Julia P. Hunn, Jonathan C. Howard, Sandra Beer, Klaus Pfeffer, Jörn Coers, Gregory A. Taylor
J Biol Chem. 2011 Sep 2; 286(35): 30471–30480. Published online 2011 Jul 12. doi: 10.1074/jbc.M111.251967
Correction in:
J Biol Chem. 2013 Apr 19; 288(16): 11504.
PMCID:
PMC3162407
AbstractArticlePDF–3.5M
13.
The IFN-γ-Inducible GTPase, Irga6, Protects Mice against Toxoplasma gondii but Not against Plasmodium berghei and Some Other Intracellular Pathogens
Oliver Liesenfeld, Iana Parvanova, Jens Zerrahn, Seong-Ji Han, Frederik Heinrich, Melba Muñoz, Frank Kaiser, Toni Aebischer, Thorsten Buch, Ari Waisman, Gaby Reichmann, Olaf Utermöhlen, Esther von Stebut, Friederike D. von Loewenich, Christian Bogdan, Sabine Specht, Michael Saeftel, Achim Hoerauf, Maria M. Mota, Stephanie Könen-Waisman, Stefan H. E. Kaufmann, Jonathan C. Howard
PLoS One. 2011; 6(6): e20568. Published online 2011 Jun 17. doi: 10.1371/journal.pone.0020568
PMCID:
PMC3117789
AbstractArticlePDF–501K
14.
The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii
Nikolaus Pawlowski, Aliaksandr Khaminets, Julia P Hunn, Natasa Papic, Andreas Schmidt, Revathy C Uthaiah, Rita Lange, Gabriela Vopper, Sascha Martens, Eva Wolf, Jonathan C Howard
BMC Biol. 2011; 9: 7. Published online 2011 Jan 28. doi: 10.1186/1741-7007-9-7
PMCID:
PMC3042988
AbstractArticlePDF–3.4M
15.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
16.
Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii
Tobias Steinfeldt, Stephanie Könen-Waisman, Lan Tong, Nikolaus Pawlowski, Tobias Lamkemeyer, L. David Sibley, Julia P. Hunn, Jonathan C. Howard
PLoS Biol. 2010 Dec; 8(12): e1000576. Published online 2010 Dec 21. doi: 10.1371/journal.pbio.1000576
Correction in:
PLoS Biol. 2015 Jul; 13(7): e1002199.
PMCID:
PMC3006384
AbstractArticlePDF–955K
17.
A Dedicated Promoter Drives Constitutive Expression of the Cell-Autonomous Immune Resistance GTPase, Irga6 (IIGP1) in Mouse Liver
Jia Zeng, Iana Angelova Parvanova, Jonathan C. Howard
PLoS One. 2009; 4(8): e6787. Published online 2009 Aug 26. doi: 10.1371/journal.pone.0006787
PMCID:
PMC2848866
AbstractArticlePDF–781K
18.
IFN-γ-Inducible Irga6 Mediates Host Resistance against Chlamydia trachomatis via Autophagy
Munir A. Al-Zeer, Hesham M. Al-Younes, Peter R. Braun, Jens Zerrahn, Thomas F. Meyer
PLoS One. 2009; 4(2): e4588. Published online 2009 Feb 26. doi: 10.1371/journal.pone.0004588
PMCID:
PMC2643846
AbstractArticlePDF–2.1M
19.
Inactive and Active States of the Interferon-inducible Resistance GTPase, Irga6, in Vivo
Natasa Papic, Julia P. Hunn, Nikolaus Pawlowski, Jens Zerrahn, Jonathan C. Howard
J Biol Chem. 2008 Nov 14; 283(46): 32143–32151. doi: 10.1074/jbc.M804846200
PMCID:
PMC2581590
AbstractArticlePDF–1.3M
20.
Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii
Julia P Hunn, Stephanie Koenen-Waisman, Natasa Papic, Nina Schroeder, Nikolaus Pawlowski, Rita Lange, Frank Kaiser, Jens Zerrahn, Sascha Martens, Jonathan C Howard
EMBO J. 2008 Oct 8; 27(19): 2495–2509. Published online 2008 Sep 4. doi: 10.1038/emboj.2008.176
PMCID:
PMC2532785
AbstractArticlePDF–1.6M

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