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Select item 111057701.

Bardet–Biedl Syndrome proteins regulate cilia disassembly during tissue maturation

Sarita Rani Patnaik, Viola Kretschmer, Lena Brücker, Sandra Schneider, Ann-Kathrin Volz, Liliana del Rocio Oancea-Castillo, Helen Louise May-Simera

Cell Mol Life Sci. 2019 Feb; 76(4): 757–775. Published online 2018 Nov 16. doi: 10.1007/s00018-018-2966-x

PMCID:: PMC11105770

Abstract Article PDF–3.0M

Select item 104316852.

An adhesion signaling axis involving Dystroglycan, β1-Integrin, and Cas adaptor proteins regulates the establishment of the cortical glial scaffold

Wenny Wong, Jason A. Estep, Alyssa M. Treptow, Niloofar Rajabli, Jennifer N. Jahncke, Teresa Ubina, Kevin M. Wright, Martin M. Riccomagno

PLoS Biol. 2023 Aug; 21(8): e3002212. Published online 2023 Aug 4. doi: 10.1371/journal.pbio.3002212

PMCID:: PMC10431685

Abstract Article PDF–12M

Select item 92529103.

The scaffold protein NEDD9 is necessary for leukemia-cell migration and disease progression in a mouse model of chronic lymphocytic leukemia

Lisa Rusyn, Sebastian Reinartz, Anastasia Nikiforov, Nelly Mikhael, Alexander vom Stein, Viktoria Kohlhas, Johannes Bloehdorn, Stephan Stilgenbauer, Philipp Lohneis, Reinhard Buettner, Sandra Robrecht, Kirsten Fischer, Christian Pallasch, Michael Hallek, Phuong-Hien Nguyen, Tamina Seeger-Nukpezah

Leukemia. 2022; 36(7): 1794–1805. Published online 2022 May 6. doi: 10.1038/s41375-022-01586-1

PMCID:: PMC9252910

Abstract Article PDF–4.9M

Select item 83132394.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 82777485.

Nedd9 restrains autophagy to limit growth of early stage non-small cell lung cancer

Alexander Y. Deneka, Meghan C. Kopp, Anna S. Nikonova, Anna V. Gaponova, Anna A. Kiseleva, Harvey H. Hensley, Douglas B. Flieder, Ilya G. Serebriiskii, Erica A. Golemis

Cancer Res. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Cancer Res. 2021 Jul 1; 81(13): 3717–3726. Published online 2021 May 18. doi: 10.1158/0008-5472.CAN-20-3626

PMCID:: PMC8277748

Abstract Article PDF–1.1M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 63514997.

A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis

Matthew R. Jones, Salma Dilai, Arun Lingampally, Cho-Ming Chao, Soula Danopoulos, Gianni Carraro, Regina Mukhametshina, Jochen Wilhelm, Eveline Baumgart-Vogt, Denise Al Alam, Chengshui Chen, Parviz Minoo, Jin San Zhang, Saverio Bellusci

Front Genet. 2018; 9: 746. Published online 2019 Jan 23. doi: 10.3389/fgene.2018.00746

PMCID:: PMC6351499

Abstract Article PDF–5.6M

Select item 62230258.

NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension

Andriy O. Samokhin, Thomas Stephens, Bradley M. Wertheim, Rui-Sheng Wang, Sara O. Vargas, Lai-Ming Yung, Minwei Cao, Marcel Brown, Elena Arons, Paul B. Dieffenbach, Jason G. Fewell, Majed Matar, Frederick P. Bowman, Kathleen J. Haley, George A. Alba, Stefano M. Marino, Rahul Kumar, Ivan O. Rosas, Aaron B. Waxman, William M. Oldham, Dinesh Khanna, Brian B. Graham, Sachiko Seo, Vadim N. Gladyshev, Paul B. Yu, Laura E. Fredenburgh, Joseph Loscalzo, Jane A. Leopold, Bradley A. Maron

Sci Transl Med. Author manuscript; available in PMC 2018 Dec 13.

Published in final edited form as: Sci Transl Med. 2018 Jun 13; 10(445): eaap7294. doi: 10.1126/scitranslmed.aap7294

PMCID:: PMC6223025

Abstract Article PDF–2.3M

Select item 59025489.

Cas Adaptor Proteins Coordinate Sensory Axon Fasciculation

Tyler A. Vahedi-Hunter, Jason A. Estep, Kylee A. Rosette, Michael L. Rutlin, Kevin M. Wright, Martin M. Riccomagno

Sci Rep. 2018; 8: 5996. Published online 2018 Apr 16. doi: 10.1038/s41598-018-24261-x

PMCID:: PMC5902548

Abstract Article PDF–4.6M

Select item 530821810.

The Proximal Signaling Network of the BCR-ABL1 Oncogene Shows a Modular Organization

Björn Titz, Tracey Low, Evangelia Komisopoulou, Sharon S Chen, Liudmilla Rubbi, Thomas G Graeber

Oncogene. Author manuscript; available in PMC 2017 Feb 14.

Published in final edited form as: Oncogene. 2010 Nov 4; 29(44): 5895–5910. Published online 2010 Aug 9. doi: 10.1038/onc.2010.331

PMCID:: PMC5308218

Abstract Article PDF–3.8M

Select item 512103311.

Actin polymerization‐dependent activation of Cas‐L promotes immunological synapse stability

Luís C Santos, David A Blair, Sudha Kumari, Michael Cammer, Thomas Iskratsch, Olivier Herbin, Konstantina Alexandropoulos, Michael L Dustin, Michael P Sheetz

Immunol Cell Biol. 2016 Nov-Dec; 94(10): 981–993. Published online 2016 Nov 1. doi: 10.1038/icb.2016.61

PMCID:: PMC5121033

Abstract Article PDF–2.6M

Select item 491897912.

Identification of Nedd9 as a TGF-β-Smad2/3 Target Gene Involved in RANKL-Induced Osteoclastogenesis by Comprehensive Analysis

Yasunori Omata, Shinya Nakamura, Takuma Koyama, Tetsuro Yasui, Jun Hirose, Naohiro Izawa, Takumi Matsumoto, Yuuki Imai, Sachiko Seo, Mineo Kurokawa, Shuichi Tsutsumi, Yuho Kadono, Chikao Morimoto, Hiroyuki Aburatani, Takeshi Miyamoto, Sakae Tanaka

PLoS One. 2016; 11(6): e0157992. Published online 2016 Jun 23. doi: 10.1371/journal.pone.0157992

PMCID:: PMC4918979

Abstract Article PDF–6.2M

Select item 436224213.

CRK proteins selectively regulate T cell migration into inflamed tissues

Yanping Huang, Fiona Clarke, Mobin Karimi, Nathan H. Roy, Edward K. Williamson, Mariko Okumura, Kazuhiro Mochizuki, Emily J.H. Chen, Tae-Ju Park, Gudrun F. Debes, Yi Zhang, Tom Curran, Taku Kambayashi, Janis K. Burkhardt

J Clin Invest. 2015 Mar 2; 125(3): 1019–1032. Published online 2015 Jan 26. doi: 10.1172/JCI77278

PMCID:: PMC4362242

Abstract Article PDF–2.9M

Select item 427437514.

A complex RARE is required for the majority of Nedd9 embryonic expression

Danielle C. Knutson, Margaret Clagett-Dame

Transgenic Res. 2015; 24(1): 123–134. Published online 2014 Aug 14. doi: 10.1007/s11248-014-9825-9

PMCID:: PMC4274375

Abstract Article PDF–2.5M

Select item 415673615.

Nedd9 restrains renal cystogenesis in Pkd1^−/− mice

Anna S. Nikonova, Olga V. Plotnikova, Victoria Serzhanova, Andrey Efimov, Igor Bogush, Kathy Q. Cai, Harvey H. Hensley, Brian L. Egleston, Andres Klein-Szanto, Tamina Seeger-Nukpezah, Erica A. Golemis

Proc Natl Acad Sci U S A. 2014 Sep 2; 111(35): 12859–12864. Published online 2014 Aug 19. doi: 10.1073/pnas.1405362111

PMCID:: PMC4156736

Abstract Article PDF–1.3M

Select item 415564816.

Src Kinase Determines the Dynamic Exchange of the Docking Protein NEDD9 (Neural Precursor Cell Expressed Developmentally Down-regulated Gene 9) at Focal Adhesions

Peta Bradbury, Cuc T. Bach, Andre Paul, Geraldine M. O'Neill

J Biol Chem. 2014 Sep 5; 289(36): 24792–24800. Published online 2014 Jul 24. doi: 10.1074/jbc.M113.544106

PMCID:: PMC4155648

Abstract Article PDF–2.4M

Select item 402095217.

“NEDD9 Regulates Actin Dynamics through Cortactin Deacetylation in an AURKA/HDAC6-dependent Manner”

Varvara K. Kozyreva, Sarah L. McLaughlin, Ryan H. Livengood, Robin A. Calkins, Laura C. Kelley, Anuradha Rajulapati, Ryan J. Ice, Matthew B. Smolkin, Scott A. Weed, Elena N. Pugacheva

Mol Cancer Res. Author manuscript; available in PMC 2015 May 1.

Published in final edited form as: Mol Cancer Res. 2014 May; 12(5): 681–693. Published online 2014 Feb 26. doi: 10.1158/1541-7786.MCR-13-0654

PMCID:: PMC4020952

Abstract Article PDF–666K

Select item 398802318.

Cas Adaptor Proteins Organize the Retinal Ganglion Cell Layer Downstream of Integrin Signaling

Martin M. Riccomagno, Lu O. Sun, Colleen M. Brady, Konstantina Alexandropoulos, Sachiko Seo, Mineo Kurokawa, Alex L. Kolodkin

Neuron. Author manuscript; available in PMC 2014 Aug 19.

Published in final edited form as: Neuron. 2014 Feb 19; 81(4): 779–786. doi: 10.1016/j.neuron.2014.01.036

PMCID:: PMC3988023

Abstract Article PDF–2.7M

Select item 370637519.

Tyrosine Y189 in the Substrate Domain of the Adhesion Docking Protein NEDD9 Is Conserved with p130Cas Y253 and Regulates NEDD9-Mediated Migration and Focal Adhesion Dynamics

Jaime B. Baquiran, Peta Bradbury, Geraldine M. O'Neill

PLoS One. 2013; 8(7): e69304. Published online 2013 Jul 9. doi: 10.1371/journal.pone.0069304

PMCID:: PMC3706375

Abstract Article PDF–2.1M

Select item 362899620.

A requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 mice

Joy L. Little, Victoria Serzhanova, Eugene Izumchenko, Brian L. Egleston, Erica Parise, Andres J. Klein-Szanto, Grace Loudon, Maria Shubina, Sachiko Seo, Mineo Kurokawa, Michael F. Ochs, Erica A. Golemis

Oncogene. Author manuscript; available in PMC 2014 Jul 23.

Published in final edited form as: Oncogene. 2014 Jan 23; 33(4): 411–420. Published online 2013 Jan 14. doi: 10.1038/onc.2012.607

PMCID:: PMC3628996

Abstract Article PDF–3.0M

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