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Select item 101128971.

Frizzled 7 modulates goblet and Paneth cell fate, and maintains homeostasis in mouse intestine

Nai-Xin Gu, Yu-Ru Guo, Sey-En Lin, Yen-Hsin Wang, I.-Hsuan Lin, Yi-Fan Chen, Yun Yen

Development. 2023 Feb 15; 150(4): dev200932. Published online 2023 Feb 14. doi: 10.1242/dev.200932

PMCID:: PMC10112897

Abstract Article

Select item 100730082.

FZD2 regulates limb development by mediating β-catenin-dependent and -independent Wnt signaling pathways

Xuming Zhu, Mingang Xu, N. Adrian Leu, Edward E. Morrisey, Sarah E. Millar

Dis Model Mech. 2023 Mar 1; 16(3): dmm049876. Published online 2023 Mar 24. doi: 10.1242/dmm.049876

PMCID:: PMC10073008

Abstract Article

Select item 94819693.

Integrated analysis of Wnt signalling system component gene expression

Paula Murphy, Chris Armit, Bill Hill, Shanmugasundaram Venkataraman, Patrick Frankel, Richard A. Baldock, Duncan R. Davidson

Development. 2022 Aug 15; 149(16): dev200312. Published online 2022 Aug 15. doi: 10.1242/dev.200312

PMCID:: PMC9481969

Abstract Article

Select item 87427654.

A FZD7-specific Antibody–Drug Conjugate Induces Ovarian Tumor Regression in Preclinical Models

Myan Do, Christina C.N. Wu, Pooja R. Sonavane, Edwin F. Juarez, Stephen R. Adams, Jason Ross, Alessandra Rodriguez y Baena, Charmi Patel, Jill P. Mesirov, Dennis A. Carson, Sunil J. Advani, Karl Willert

Mol Cancer Ther. 2022 Jan 1; 21(1): 113–124. Published online 2021 Oct 19. doi: 10.1158/1535-7163.MCT-21-0548

PMCID:: PMC8742765

Abstract Article PDF–1.3M

Select item 79116715.

Extrinsic Regulators of mRNA Translation in Developing Brain: Story of WNTs

Yongkyu Park, Midori Lofton, Diana Li, Mladen-Roko Rasin

Cells. 2021 Feb; 10(2): 253. Published online 2021 Jan 28. doi: 10.3390/cells10020253

PMCID:: PMC7911671

Abstract Article PDF–5.1M

Select item 76452136.

Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis

Jiali Ru, Dianlei Guo, Jiaying Fan, Jiao Zhang, Rong Ju, Hong Ouyang, Lai Wei, Yizhi Liu, Chunqiao Liu

Invest Ophthalmol Vis Sci. 2020 Nov; 61(13): 6. Published online 2020 Nov 3. doi: 10.1167/iovs.61.13.6

PMCID:: PMC7645213

Abstract Article PDF–35M

Select item 75755937.

WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion

Irene Rodriguez-Hernandez, Oscar Maiques, Leonie Kohlhammer, Gaia Cantelli, Anna Perdrix-Rosell, Joanne Monger, Bruce Fanshawe, Victoria L. Bridgeman, Sophia N. Karagiannis, Rosa M. Penin, Joaquim Marcolval, Rosa M. Marti, Xavier Matias-Guiu, Gilbert O. Fruhwirth, Jose L. Orgaz, Ilaria Malanchi, Victoria Sanz-Moreno

Nat Commun. 2020; 11: 5315. Published online 2020 Oct 20. doi: 10.1038/s41467-020-18951-2

PMCID:: PMC7575593

Abstract Article PDF–6.7M

Select item 72978128.

Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening

Jiuann-Huey I. Lin, Timothy N. Feinstein, Anupma Jha, Jacob T. McCleary, Juan Xu, Angelo B. Arrigo, Grace Rong, Lindsey M. Maclay, Taylor Ridge, XinXiu Xu, Cecilia W. Lo

Commun Biol. 2020; 3: 312. Published online 2020 Jun 16. doi: 10.1038/s42003-020-1035-9

PMCID:: PMC7297812

Abstract Article PDF–9.8M

Select item 72251299.

Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk

SungKyoung Lee, Matthew J. Sears, Zijun Zhang, Hong Li, Imad Salhab, Philippe Krebs, Yi Xing, Hyun-Duck Nah, Trevor Williams, Russ P. Carstens

Development. 2020 Nov 1; 147(21): dev187369. Published online 2020 May 4. doi: 10.1242/dev.187369

PMCID:: PMC7225129

Abstract Article

Select item 646134910.

Molecular determinants of WNT9b responsiveness in nephron progenitor cells

Kyle K. Dickinson, Leah C. Hammond, Courtney M. Karner, Nicholas D. Hastie, Thomas J. Carroll, Paul Goodyer

PLoS One. 2019; 14(4): e0215139. Published online 2019 Apr 12. doi: 10.1371/journal.pone.0215139

PMCID:: PMC6461349

Abstract Article PDF–2.0M

Select item 643372111.

MicroRNA‐488 inhibits endometrial glandular epithelial cell proliferation, migration, and invasion in endometriosis mice via Wnt by inhibiting FZD7

Hui Zhu, Xi‐Xia Cao, Juan Liu, Hua Hua

J Cell Mol Med. 2019 Apr; 23(4): 2419–2430. Published online 2019 Feb 7. doi: 10.1111/jcmm.14078

PMCID:: PMC6433721

Abstract Article PDF–1.2M

Select item 628131912.

Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment

Lori L O'Brien, Alexander N Combes, Kieran M Short, Nils O Lindström, Peter H Whitney, Luise A Cullen-McEwen, Adler Ju, Ahmed Abdelhalim, Odyssé Michos, John F Bertram, Ian M Smyth, Melissa H Little, Andrew P McMahon

eLife. 2018; 7: e40392. Published online 2018 Dec 5. doi: 10.7554/eLife.40392

PMCID:: PMC6281319

Abstract Article PDF–11M

Select item 624031813.

Activation of Wnt signaling reduces ipsilaterally projecting retinal ganglion cells in pigmented retina

Lena Iwai-Takekoshi, Revathi Balasubramanian, Austen Sitko, Rehnuma Khan, Samuel Weinreb, Kiera Robinson, Carol Mason

Development. 2018 Nov 1; 145(21): dev163212. Published online 2018 Nov 2. doi: 10.1242/dev.163212

PMCID:: PMC6240318

Abstract Article

Select item 594645814.

Wnt Signaling Mediates LTP-Dependent Spine Plasticity and AMPAR Localization through Frizzled-7 Receptors

Faye McLeod, Alessandro Bossio, Aude Marzo, Lorenza Ciani, Sara Sibilla, Saad Hannan, Gemma A. Wilson, Ernest Palomer, Trevor G. Smart, Alasdair Gibb, Patricia C. Salinas

Cell Rep. 2018 Apr 24; 23(4): 1060–1071. Published online 2018 Apr 25. doi: 10.1016/j.celrep.2018.03.119