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Select item 102168011.

An XBP1s–PIM-2 positive feedback loop controls IL-15–mediated survival of natural killer cells

Shoubao Ma, Jingjing Han, Zhenlong Li, Sai Xiao, Jianying Zhang, Jiazhuo Yan, Tingting Tang, Tasha Barr, Andrew S. Kraft, Michael A. Caligiuri, Jianhua Yu

Sci Immunol. Author manuscript; available in PMC 2023 May 26.

Published in final edited form as: Sci Immunol. 2023 Mar 17; 8(81): eabn7993. Published online 2023 Mar 10. doi: 10.1126/sciimmunol.abn7993

PMCID:: PMC10216801

Abstract Article PDF–2.2M

Select item 94778452.

Phosphorylation of PFKFB4 by PIM2 promotes anaerobic glycolysis and cell proliferation in endometriosis

Chao Lu, Pengyun Qiao, Ruihai Fu, Yadi Wang, Jiayi Lu, Xi Ling, Lu Liu, Yujun Sun, Chune Ren, Zhenhai Yu

Cell Death Dis. 2022 Sep; 13(9): 790. Published online 2022 Sep 15. doi: 10.1038/s41419-022-05241-6

Correction in:: Cell Death Dis. 2024 Jul; 15(7): 469.

PMCID:: PMC9477845

Abstract Article PDF–12M

Select item 79438933.

PIM2‐mediated phosphorylation contributes to granulosa cell survival via resisting apoptosis during folliculogenesis

Lei Wang, Yaru Chen, Shang Wu, Ling Wang, Feng Tan, Fenge Li

Clin Transl Med. 2021 Mar; 11(3): e359. Published online 2021 Mar 9. doi: 10.1002/ctm2.359

PMCID:: PMC7943893

Article PDF–2.3M

Select item 75635064.

PIM1 Promotes Survival of Cardiomyocytes by Upregulating c-Kit Protein Expression

David E. Ebeid, Fareheh Firouzi, Carolina Y. Esquer, Julian M. Navarrete, Bingyan J. Wang, Natalie A. Gude, Mark A. Sussman

Cells. 2020 Sep; 9(9): 2001. Published online 2020 Aug 31. doi: 10.3390/cells9092001

PMCID:: PMC7563506

Abstract Article PDF–2.0M

Select item 67339495.

TRAF3 regulates the oncogenic proteins Pim2 and c-Myc to restrain survival in normal and malignant B cells

Amy L. Whillock, Nurbek Mambetsariev, Wai W. Lin, Laura L. Stunz, Gail A. Bishop

Sci Rep. 2019; 9: 12884. Published online 2019 Sep 9. doi: 10.1038/s41598-019-49390-9

Correction in:: Sci Rep. 2019; 9: 17502.

PMCID:: PMC6733949

Abstract Article PDF–2.1M

Select item 60259866.

PIM-2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity

Anusara Daenthanasanmak, Yongxia Wu, Supinya Iamsawat, Hung D. Nguyen, David Bastian, MengMeng Zhang, M. Hanief Sofi, Shilpak Chatterjee, Elizabeth G. Hill, Shikhar Mehrotra, Andrew S. Kraft, Xue-Zhong Yu

J Clin Invest. 2018 Jul 2; 128(7): 2787–2801. Published online 2018 May 21. doi: 10.1172/JCI95407

PMCID:: PMC6025986

Abstract Article PDF–6.3M

Select item 45364307.

Pim-2 Kinase Influences Regulatory T Cell Function and Stability by Mediating Foxp3 Protein N-terminal Phosphorylation

Guoping Deng, Yasuhiro Nagai, Yan Xiao, Zhiyuan Li, Shujia Dai, Takuya Ohtani, Alison Banham, Bin Li, Shiaw-Lin Wu, Wayne Hancock, Arabinda Samanta, Hongtao Zhang, Mark I. Greene

J Biol Chem. 2015 Aug 14; 290(33): 20211–20220. Published online 2015 May 18. doi: 10.1074/jbc.M115.638221

PMCID:: PMC4536430

Abstract Article PDF–1.8M

Select item 42547558.

Metabolic Dysfunction Consistent with Premature Aging Results from Deletion of Pim Kinases

Shabana Din, Mathias H Konstandin, Bevan Johnson, Jacqueline Emathinger, Mirko Völkers, Haruhiro Toko, Brett Collins, Lucy Ormachea, Kaitlen Samse, Dieter A Kubli, Andrea De La Torre, Andrew S Kraft, Asa B Gustafsson, Daniel P Kelly, Mark A Sussman

Circ Res. Author manuscript; available in PMC 2015 Jul 18.

Published in final edited form as: Circ Res. 2014 Jul 18; 115(3): 376–387. Published online 2014 Jun 10. doi: 10.1161/CIRCRESAHA.115.304441

PMCID:: PMC4254755

Abstract Article PDF–2.6M

Select item 40022209.

Inhibition of Pim2-prolonged skin allograft survival through the apoptosis regulation pathway

Hongtao Liu, Chao Zhang, Ting Liang, Jing Song, Jing Hao, Guihua Hou

Cell Mol Immunol. 2012 Nov; 9(6): 503–510. Published online 2012 Oct 22. doi: 10.1038/cmi.2012.41

PMCID:: PMC4002220

Abstract Article PDF–1.0M

Select item 366411710.

Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cells

Ningfei An, Ying-Wei Lin, Sandeep Mahajan, Joshua N. Kellner, Yong Wang, Zihai Li, Andrew S. Kraft, Yubin Kang

Stem Cells. Author manuscript; available in PMC 2014 Jun 1.

Published in final edited form as: Stem Cells. 2013 Jun; 31(6): 1202–1212. doi: 10.1002/stem.1369

PMCID:: PMC3664117

Abstract Article PDF–1.7M

Select item 361028311.

Abnormal hematopoietic phenotypes in Pim kinase triple knockout mice

Ningfei An, Andrew S Kraft, Yubin Kang

J Hematol Oncol. 2013; 6: 12. Published online 2013 Jan 29. doi: 10.1186/1756-8722-6-12

PMCID:: PMC3610283

Abstract Article PDF–1.0M

Select item 326086412.

RAG-induced DNA double-strand breaks signal through Pim2 to promote pre–B cell survival and limit proliferation

Jeffrey J. Bednarski, Andrew Nickless, Deepta Bhattacharya, Rupesh H. Amin, Mark S. Schlissel, Barry P. Sleckman

J Exp Med. 2012 Jan 16; 209(1): 11–17. doi: 10.1084/jem.20112078

PMCID:: PMC3260864

Abstract Article PDF–1.8M

Select item 325163413.

Pim kinase inhibitors sensitize prostate cancer cells to apoptosis triggered by Bcl-2 family inhibitor ABT-737

Jin H. Song, Andrew S. Kraft

Cancer Res. Author manuscript; available in PMC 2013 Jan 1.

Published in final edited form as: Cancer Res. 2012 Jan 1; 72(1): 294–303. Published online 2011 Nov 11. doi: 10.1158/0008-5472.CAN-11-3240

PMCID:: PMC3251634

Abstract Article PDF–1.9M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 317109315.

Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma

Jonathan H. Schatz, Elisa Oricchio, Andrew L. Wolfe, Man Jiang, Irina Linkov, Jocelyn Maragulia, Weiji Shi, Zhigang Zhang, Vinagolu K. Rajasekhar, Nen C. Pagano, John A. Porco, Jr., Julie Teruya-Feldstein, Neal Rosen, Andrew D. Zelenetz, Jerry Pelletier, Hans-Guido Wendel

J Exp Med. 2011 Aug 29; 208(9): 1799–1807. doi: 10.1084/jem.20110846

PMCID:: PMC3171093

Abstract Article PDF–2.5M

Select item 302102216.

The Pim protein kinases regulate energy metabolism and cell growth

Zanna Beharry, Sandeep Mahajan, Marina Zemskova, Ying-Wei Lin, Baby G. Tholanikunnel, Zuping Xia, Charles D. Smith, Andrew S. Kraft

Proc Natl Acad Sci U S A. 2011 Jan 11; 108(2): 528–533. Published online 2010 Dec 27. doi: 10.1073/pnas.1013214108

PMCID:: PMC3021022

Abstract Article PDF–951K

Select item 296726317.

Proviral integration site 2 is required for interleukin-6 expression induced by interleukin-1, tumour necrosis factor-α and lipopolysaccharide

Jianfei Yang, Xiang Li, Adedayo Hanidu, Tin M Htut, Rosemarie Sellati, Lian Wang, Huiping Jiang, Jun Li

Immunology. 2010 Oct; 131(2): 174–182. doi: 10.1111/j.1365-2567.2010.03286.x

PMCID:: PMC2967263

Abstract Article PDF–445K

Select item 294199618.

A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma

Ying-Wei Lin, Zanna M. Beharry, Elizabeth G. Hill, Jin H. Song, Wenxue Wang, Zuping Xia, Zhenhua Zhang, Peter D. Aplan, Jon C. Aster, Charles D. Smith, Andrew S. Kraft

Blood. 2010 Jan 28; 115(4): 824–833. Prepublished online 2009 Nov 23. doi: 10.1182/blood-2009-07-233445

PMCID:: PMC2941996

Abstract Article

Select item 274298419.

Ig?⁺ B cell development but not Ig? editing depends on NF-?B signals

Emmanuel Derudder, Emily J Cadera, J Christoph Vahl, Jing Wang, Casey J. Fox, Shan Zha, Geert van Loo, Manolis Pasparakis, Mark S Schlissel, Marc Schmidt-Supprian, Klaus Rajewsky

Nat Immunol. Author manuscript; available in PMC 2009 Dec 1.

Published in final edited form as: Nat Immunol. 2009 Jun; 10(6): 647–654. Published online 2009 May 3. doi: 10.1038/ni.1732

PMCID:: PMC2742984

Abstract Article PDF–706K

Select item 273716420.

Dissection of PIM serine/threonine kinases in FLT3-ITD–induced leukemogenesis reveals PIM1 as regulator of CXCL12–CXCR4-mediated homing and migration

Rebekka Grundler, Laurent Brault, Christelle Gasser, Alex N. Bullock, Tobias Dechow, Sabine Woetzel, Vanda Pogacic, Antonello Villa, Sabine Ehret, Georgina Berridge, Anke Spoo, Christine Dierks, Andrea Biondi, Stefan Knapp, Justus Duyster, Juerg Schwaller

J Exp Med. 2009 Aug 31; 206(9): 1957–1970. doi: 10.1084/jem.20082074