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Items: 1 to 20 of 62

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Depletion of G9A attenuates imiquimod-induced psoriatic dermatitis via targeting EDAR-NF-κB signaling in keratinocyte
Zhiqin Fang, Yutong Wang, Bo Huang, Xiang Chen, Rundong Jiang, Mingzhu Yin
Cell Death Dis. 2023 Sep; 14(9): 627. Published online 2023 Sep 22. doi: 10.1038/s41419-023-06134-y
PMCID:
PMC10517171
AbstractArticlePDF–9.7M
3.
Ectodysplasin signaling via Xedar is required for mammary gland morphogenesis
Abigail R. Wark, Daniel Aldea, Reiko R. Tomizawa, Blerina Kokalari, Bailey Warder, Yana G. Kamberov
J Invest Dermatol. Author manuscript; available in PMC 2024 Aug 1.
Published in final edited form as: J Invest Dermatol. 2023 Aug; 143(8): 1529–1537.e2. Published online 2023 Feb 18. doi: 10.1016/j.jid.2023.02.007
PMCID:
PMC10363239
AbstractArticlePDF–1.0M
4.
A Foxo1-Klf2-S1pr1-Gnai1-Rac1 signaling axis is a critical mediator of Ostm1 regulatory network in T lymphopoiesis
Marie S. Mutabaruka, Monica Pata, Jean Vacher
iScience. 2022 Apr 15; 25(4): 104160. Published online 2022 Mar 25. doi: 10.1016/j.isci.2022.104160
PMCID:
PMC9010627
AbstractArticlePDF–5.7M
5.
The EDA-deficient mouse has Zymbal's gland hypoplasia and acute otitis externa
Jorge del-Pozo, Denis J. Headon, James D. Glover, Ali Azar, Sonia Schuepbach-Mallepell, Mahmood F. Bhutta, Jon Riddell, Scott Maxwell, Elspeth Milne, Pascal Schneider, Michael Cheeseman
Dis Model Mech. 2022 Mar 1; 15(3): dmm049034. Published online 2022 Mar 30. doi: 10.1242/dmm.049034
PMCID:
PMC8990926
AbstractArticle
6.
Limb development genes underlie variation in human fingerprint patterns
Jinxi Li, James D. Glover, Haiguo Zhang, Meifang Peng, Jingze Tan, Chandana Basu Mallick, Dan Hou, Yajun Yang, Sijie Wu, Yu Liu, Qianqian Peng, Shijie C. Zheng, Edie I. Crosse, Alexander Medvinsky, Richard A. Anderson, Helen Brown, Ziyu Yuan, Shen Zhou, Yanqing Xu, John P. Kemp, Yvonne Y.W. Ho, Danuta Z. Loesch, Lizhong Wang, Yingxiang Li, Senwei Tang, Xiaoli Wu, Robin G. Walters, Kuang Lin, Ruogu Meng, Jun Lv, Jonathan M. Chernus, Katherine Neiswanger, Eleanor Feingold, David M. Evans, Sarah E. Medland, Nicholas G. Martin, Seth M. Weinberg, Mary L. Marazita, Gang Chen, Zhengming Chen, Yong Zhou, Michael Cheeseman, Lan Wang, Li Jin, Denis J. Headon, Sijia Wang
Cell. 2022 Jan 6; 185(1): 95–112.e18. doi: 10.1016/j.cell.2021.12.008
PMCID:
PMC8740935
AbstractArticle
7.
Lhx2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth
Philip Tomann, Ralf Paus, Sarah E. Millar, Claus Scheidereit, Ruth Schmidt-Ullrich
Development. 2016 May 1; 143(9): 1512–1522. Published online 2016 May 3. doi: 10.1242/dev.130898
PMCID:
PMC6514410
AbstractArticle
8.
Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling
Youngwook Ahn, Carrie Sims, Jennifer M. Logue, Scott D. Weatherbee, Robb Krumlauf
Development. 2013 Feb 1; 140(3): 583–593. Published online 2013 Jan 4. doi: 10.1242/dev.085118
PMCID:
PMC6514302
AbstractArticle
9.
Edar is a downstream target of beta-catenin and drives collagen accumulation in the mouse prostate
Kyle A. Wegner, Vatsal Mehta, Jeanette A. Johansson, Brett R. Mueller, Kimberly P. Keil, Lisa L. Abler, Paul C. Marker, M. Mark Taketo, Denis J. Headon, Chad M. Vezina
Biol Open. 2019 Mar 15; 8(3): bio037945. Published online 2019 Feb 11. doi: 10.1242/bio.037945
PMCID:
PMC6451354
AbstractArticlePDF–1.4M
10.
Modeling Edar expression reveals the hidden dynamics of tooth signaling center patterning
Alexa Sadier, Monika Twarogowska, Klara Steklikova, Luke Hayden, Anne Lambert, Pascal Schneider, Vincent Laudet, Maria Hovorakova, Vincent Calvez, Sophie Pantalacci
PLoS Biol. 2019 Feb; 17(2): e3000064. Published online 2019 Feb 7. doi: 10.1371/journal.pbio.3000064
PMCID:
PMC6382175
AbstractArticlePDF–3.4M
11.
The Ectodysplasin receptor EDAR acts as a tumor suppressor in melanoma by conditionally inducing cell death
Jonathan Vial, Amélie Royet, Philippe Cassier, Antonin Tortereau, Sarah Dinvaut, Denis Maillet, Lise Gratadou-Hupon, Marion Creveaux, Alexa Sadier, Garance Tondeur, Sophie Léon, Lauriane Depaepe, Sophie Pantalacci, Arnaud de la Fouchardière, Olivier Micheau, Stéphane Dalle, Vincent Laudet, Patrick Mehlen, Marie Castets
Cell Death Differ. 2019 Mar; 26(3): 443–454. Published online 2018 May 31. doi: 10.1038/s41418-018-0128-1
PMCID:
PMC6370843
AbstractArticlePDF–2.0M
12.
Dermal Condensate Niche Fate Specification Occurs Prior to Formation and Is Placode Progenitor Dependent
Ka-Wai Mok, Nivedita Saxena, Nicholas Heitman, Laura Grisanti, Devika Srivastava, Mauro Muraro, Tina Jacob, Rachel Sennett, Zichen Wang, Yutao Su, Lu M. Yang, Avi Ma’ayan, David M. Ornitz, Maria Kasper, Michael Rendl
Dev Cell. Author manuscript; available in PMC 2020 Jan 7.
Published in final edited form as: Dev Cell. 2019 Jan 7; 48(1): 32–48.e5. Published online 2018 Dec 27. doi: 10.1016/j.devcel.2018.11.034
PMCID:
PMC6370312
AbstractArticlePDF–4.9M
13.
Single-cell analysis reveals a hair follicle dermal niche molecular differentiation trajectory that begins prior to morphogenesis
Khusali Gupta, Jonathan Levinsohn, George Linderman, Demeng Chen, Thomas Yang Sun, Danni Dong, M. Mark Taketo, Marcus Bosenberg, Yuval Kluger, Keith Choate, Peggy Myung
Dev Cell. Author manuscript; available in PMC 2020 Jan 7.
Published in final edited form as: Dev Cell. 2019 Jan 7; 48(1): 17–31.e6. Published online 2018 Dec 27. doi: 10.1016/j.devcel.2018.11.032
PMCID:
PMC6361530
AbstractArticlePDF–2.8M
14.
Single cell and open chromatin analysis reveals molecular origin of epidermal cells of the skin
Xiying Fan, Dongmei Wang, Jeremy Evan Burgmaier, Yudong Teng, Rose-Anne Romano, Satrajit Sinha, Rui Yi
Dev Cell. Author manuscript; available in PMC 2019 Oct 8.
Published in final edited form as: Dev Cell. 2018 Oct 8; 47(1): 21–37.e5. Published online 2018 Sep 13. doi: 10.1016/j.devcel.2018.08.010
Correction in:
Dev Cell. 2018 Oct 8; 47(1): 133.
PMCID:
PMC6177292
AbstractArticlePDF–4.4M
15.
Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation
Leah C Biggs, Otto JM Mäkelä, Satu-Marja Myllymäki, Rishi Das Roy, Katja Närhi, Johanna Pispa, Tuija Mustonen, Marja L Mikkola
eLife. 2018; 7: e36468. Published online 2018 Jul 31. doi: 10.7554/eLife.36468
PMCID:
PMC6107334
AbstractArticlePDF–8.7M
16.
The Impact of the Eda Pathway on Tooth Root Development
J.M. Fons Romero, H. Star, R. Lav, S. Watkins, M. Harrison, M. Hovorakova, D. Headon, A.S. Tucker
J Dent Res. 2017 Oct; 96(11): 1290–1297. Published online 2017 Aug 16. doi: 10.1177/0022034517725692
PMCID:
PMC5613883
AbstractArticlePDF–1.0M
17.
Ectodysplasin target gene Fgf20 regulates mammary bud growth and ductal invasion and branching during puberty
Teresa Elo, Päivi H. Lindfors, Qiang Lan, Maria Voutilainen, Ewelina Trela, Claes Ohlsson, Sung-Ho Huh, David M. Ornitz, Matti Poutanen, Beatrice A. Howard, Marja L. Mikkola
Sci Rep. 2017; 7: 5049. Published online 2017 Jul 11. doi: 10.1038/s41598-017-04637-1
PMCID:
PMC5505952
AbstractArticlePDF–6.1M
18.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
19.
Ectodysplasin signalling deficiency in mouse models of hypohidrotic ectodermal dysplasia leads to middle ear and nasal pathology
Ali Azar, Chiara Piccinelli, Helen Brown, Denis Headon, Michael Cheeseman
Hum Mol Genet. 2016 Aug 15; 25(16): 3564–3577. Published online 2016 Jul 4. doi: 10.1093/hmg/ddw202
PMCID:
PMC5179950
AbstractArticlePDF–2.1M
20.
Ectodysplasin A Pathway Contributes to Human and Murine Skin Repair
Clare L. Garcin, Kenneth M. Huttner, Neil Kirby, Pascal Schneider, Matthew J. Hardman
J Invest Dermatol. 2016 May; 136(5): 1022–1030. doi: 10.1016/j.jid.2015.09.002
PMCID:
PMC4967474
AbstractArticle

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