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Select item 108295211.

GPAT1 Deficiency in Mice Modulates NASH Progression in a Model-Dependent Manner

Kathleen R. Smith, Wenshan Wang, Melissa R. Miller, Magalie Boucher, Jessica E. Reynold, Natalie A. Daurio, Dongmei Li, Dinesh Hirenallur-Shanthappa, Youngwook Ahn, David A. Beebe, Kenneth L. Kelly, Trenton T. Ross, Kendra K. Bence, Min Wan

Cell Mol Gastroenterol Hepatol. 2024; 17(2): 279–291. Published online 2023 Oct 14. doi: 10.1016/j.jcmgh.2023.10.002

PMCID:: PMC10829521

Abstract Article PDF–5.0M

Select item 107743622.

miR-195b is required for proper cellular homeostasis in the elderly

Maria del Mar Muñoz-Gallardo, Carlos Garcia-Padilla, Cristina Vicente-Garcia, Jaime Carvajal, Amelia Arenega, Diego Franco

Sci Rep. 2024; 14: 810. Published online 2024 Jan 8. doi: 10.1038/s41598-024-51256-8

PMCID:: PMC10774362

Abstract Article PDF–3.7M

Select item 103218623.

Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease

Zixi Wang, Shijia Zhu, Yuemeng Jia, Yunguan Wang, Naoto Kubota, Naoto Fujiwara, Ruth Gordillo, Cheryl Lewis, Min Zhu, Tripti Sharma, Lin Li, Qiyu Zeng, Yu-Hsuan Lin, Meng-Hsiung Hsieh, Purva Gopal, Tao Wang, Matt Hoare, Peter Campbell, Yujin Hoshida, Hao Zhu

Cell. Author manuscript; available in PMC 2024 Apr 27.

Published in final edited form as: Cell. 2023 Apr 27; 186(9): 1968–1984.e20. Published online 2023 Apr 10. doi: 10.1016/j.cell.2023.03.014

PMCID:: PMC10321862

Abstract Article PDF–4.6M

Select item 93864644.

The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation

Ziyi Song, Alus M. Xiaoli, Youlei Li, Gerile Siqin, Tian Wu, Randy Strich, Jeffrey E. Pessin, Fajun Yang

Mol Metab. 2022 Oct; 64: 101548. Published online 2022 Jul 19. doi: 10.1016/j.molmet.2022.101548

PMCID:: PMC9386464

Abstract Article PDF–6.6M

Select item 75830335.

GPAT Gene Silencing in Muscle Reduces Diacylglycerols Content and Improves Insulin Action in Diet-Induced Insulin Resistance

Iwona Kojta, Piotr Zabielski, Kamila Roszczyc-Owsiejczuk, Monika Imierska, Emilia Sokołowska, Agnieszka Błachnio-Zabielska

Int J Mol Sci. 2020 Oct; 21(19): 7369. Published online 2020 Oct 6. doi: 10.3390/ijms21197369

PMCID:: PMC7583033

Abstract Article PDF–3.8M

Select item 73684946.

The sperm associated antigen 6 interactome and its role in spermatogenesis

Yunhao Liu, Ling Zhang, Wei Li, Yuhong Li, Junpin Liu, Shiyang Zhang, Guanglun Pin, Shizhen Song, Pierre F Ray, Christophe Arnoult, Chunghee Cho, Balbina Garcia-Reyes, Uwe Knippschild, Jerome F. Strauss, III, Zhibing Zhang

Reproduction. Author manuscript; available in PMC 2020 Jul 18.

Published in final edited form as: Reproduction. 2019 Aug; 158(2): 181–197. doi: 10.1530/REP-18-0522

PMCID:: PMC7368494

Abstract Article PDF–1.8M

Select item 63692967.

Thioesterase superfamily member 2 promotes hepatic insulin resistance in the setting of glycerol-3-phosphate acyltransferase 1–induced steatosis

Veronika Tillander, Akihiro Miniami, Michele Alves-Bezerra, Rosalind A. Coleman, David E. Cohen

J Biol Chem. 2019 Feb 8; 294(6): 2009–2020. Published online 2018 Dec 6. doi: 10.1074/jbc.RA118.005184

PMCID:: PMC6369296

Abstract Article PDF–2.9M

Select item 50452008.

Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury

Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa

PLoS Genet. 2016 Sep; 12(9): e1006355. Published online 2016 Sep 30. doi: 10.1371/journal.pgen.1006355

PMCID:: PMC5045200

Abstract Article PDF–2.9M

Select item 48239289.

Glycerol-3-phosphate acyltransferase-1 upregulation by O-GlcNAcylation of Sp1 protects against hypoxia-induced mouse embryonic stem cell apoptosis via mTOR activation

H J Lee, J M Ryu, Y H Jung, K H Lee, D I Kim, H J Han

Cell Death Dis. 2016 Mar; 7(3): e2158. Published online 2016 Mar 24. doi: 10.1038/cddis.2015.410

PMCID:: PMC4823928

Abstract Article PDF–4.4M

Select item 476699010.

SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression

Laurent Vergnes, Robert G. Chin, Thomas de Aguiar Vallim, Loren G. Fong, Timothy F. Osborne, Stephen G. Young, Karen Reue

J Lipid Res. 2016 Mar; 57(3): 410–421. doi: 10.1194/jlr.M064022

PMCID:: PMC4766990

Abstract Article PDF–1.7M

Select item 465317511.

Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity

Tatiana L. Fonseca, Gustavo W. Fernandes, Elizabeth A. McAninch, Barbara M. L. C. Bocco, Sherine M. Abdalla, Miriam O. Ribeiro, Petra Mohácsik, Csaba Fekete, Daofeng Li, Xiaoyun Xing, Ting Wang, Balázs Gereben, Antonio C. Bianco

Proc Natl Acad Sci U S A. 2015 Nov 10; 112(45): 14018–14023. Published online 2015 Oct 27. doi: 10.1073/pnas.1508943112

PMCID:: PMC4653175

Abstract Article PDF–1.0M

Select item 416930512.

Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential for murine CD4⁺ T cell metabolic activation

Robert Faris, Yang-Yi Fan, Alejandra DeAngulo, Robert S. Chapkin, Linda A. deGraffenried, Christopher A. Jolly

Biochim Biophys Acta. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: Biochim Biophys Acta. 2014 Oct; 1842(10): 1475–1482. Published online 2014 Jul 24. doi: 10.1016/j.bbalip.2014.07.009

PMCID:: PMC4169305

Abstract Article PDF–1.5M

Select item 412157913.

Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor

Chongben Zhang, Daniel E. Cooper, Trisha J. Grevengoed, Lei O. Li, Eric L. Klett, James M. Eaton, Thurl E. Harris, Rosalind A. Coleman

Am J Physiol Endocrinol Metab. 2014 Aug 1; 307(3): E305–E315. Published online 2014 Jun 17. doi: 10.1152/ajpendo.00034.2014

PMCID:: PMC4121579

Abstract Article

Select item 407349414.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Abstract Article PDF–2.1M

Select item 377972515.

Glycerol-3-phosphate Acyltransferase (GPAT)-1, but Not GPAT4, Incorporates Newly Synthesized Fatty Acids into Triacylglycerol and Diminishes Fatty Acid Oxidation

Angela A. Wendel, Daniel E. Cooper, Olga R. Ilkayeva, Deborah M. Muoio, Rosalind A. Coleman

J Biol Chem. 2013 Sep 20; 288(38): 27299–27306. Published online 2013 Aug 1. doi: 10.1074/jbc.M113.485219

PMCID:: PMC3779725

Abstract Article PDF–782K

Select item 376483616.

Hypoxia-inducible Factor-2α-dependent Hypoxic Induction of Wnt10b Expression in Adipogenic Cells

Young-Kwon Park, Bongju Park, Seongyeol Lee, Kang Choi, Yunwon Moon, Hyunsung Park

J Biol Chem. 2013 Sep 6; 288(36): 26311–26322. Published online 2013 Jul 30. doi: 10.1074/jbc.M113.500835

PMCID:: PMC3764836

Abstract Article PDF–3.4M

Select item 364029117.

Mice Deficient in Glycerol-3-Phosphate Acyltransferase-1 Have a Reduced Susceptibility to Liver Cancer

Jessica M. Ellis, David S. Paul, Michael A. Depetrillo, Bhanu P. Singh, David E. Malarkey, Rosalind A. Coleman

Toxicol Pathol. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: Toxicol Pathol. 2012 Apr; 40(3): 513–521. Published online 2012 Jan 3. doi: 10.1177/0192623311432298

PMCID:: PMC3640291

Abstract Article PDF–3.4M

Select item 344789918.

Role of DNA Methylation in the Regulation of Lipogenic Glycerol-3-Phosphate Acyltransferase 1 Gene Expression in the Mouse Neonatal Liver

Tatsuya Ehara, Yasutomi Kamei, Mayumi Takahashi, Xunmei Yuan, Sayaka Kanai, Erina Tamura, Miyako Tanaka, Tomomi Yamazaki, Shinji Miura, Osamu Ezaki, Takayoshi Suganami, Masaki Okano, Yoshihiro Ogawa

Diabetes. 2012 Oct; 61(10): 2442–2450. Published online 2012 Sep 13. doi: 10.2337/db11-1834

PMCID:: PMC3447899

Abstract Article PDF–1.5M

Select item 328555919.

Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition

Tal M. Lewin, Hendrik de Jong, Nicole J. M. Schwerbrock, Linda E. Hammond, Steven M. Watkins, Terry P. Combs, Rosalind A. Coleman

Biochim Biophys Acta. Author manuscript; available in PMC 2012 Feb 23.

Published in final edited form as: Biochim Biophys Acta. 2008 Jun-Jul; 1781(6-7): 352–358. Published online 2008 May 15. doi: 10.1016/j.bbalip.2008.05.001