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Select item 110871211.

Aberrant expression of thyroidal hormone receptor α exasperating mitochondrial dysfunction induced sarcopenia in aged mice

Yunlu Sheng, Xiaoxia Zhu, Lijun Wei, Yuxin Zou, Xinyu Qi, Runqing Shi, Wenli Xu, Xiaodong Wang, Guoxian Ding, Yu Duan

Aging (Albany NY) 2024 Apr 30; 16(8): 7141–7152. Published online 2024 Apr 18. doi: 10.18632/aging.205748

PMCID:: PMC11087121

Abstract Article PDF–1.9M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 100817113.

Morphological and Functional Colonic Defects Caused by a Mutated Thyroid Hormone Receptor α

Minjun Kim, Michael Kruhlak, Victoria Hoffmann, Patricia Zerfas, Kevin Bishop, Woo Kyung Lee Doolittle, Elijah F. Edmondson, Yuelin Jack Zhu, Sheue-yann Cheng

Thyroid. February 2023; 33(2): 239–250. Published online 2023 Feb 14. doi: 10.1089/thy.2022.0336

PMCID:: PMC10081711

Abstract Article PDF–1.4M

Select item 97181184.

Regulation of the THRA gene, encoding the thyroid hormone nuclear receptor TRα1, in intestinal lesions

Maria Virginia Giolito, Théo La Rosa, Diana Farhat, Serguei Bodoirat, Gabriela D. A. Guardia, Claire Domon‐Dell, Pedro A. F. Galante, Jean‐Noel Freund, Michelina Plateroti

Mol Oncol. 2022 Dec; 16(22): 3975–3993. Published online 2022 Oct 10. doi: 10.1002/1878-0261.13298

PMCID:: PMC9718118

Abstract Article PDF–2.2M

Select item 96837935.

Brown adipocytes local response to thyroid hormone is required for adaptive thermogenesis in adult male mice

Yanis Zekri, Romain Guyot, Inés Garteizgogeascoa Suñer, Laurence Canaple, Amandine Gautier Stein, Justine Vily Petit, Denise Aubert, Sabine Richard, Frédéric Flamant, Karine Gauthier

eLife. 2022; 11: e81996. Published online 2022 Nov 14. doi: 10.7554/eLife.81996

PMCID:: PMC9683793

Abstract Article PDF–5.9M

Select item 96056926.

Little skate genome provides insights into genetic programs essential for limb-based locomotion

DongAhn Yoo, Junhee Park, Chul Lee, Injun Song, Young Ho Lee, Tery Yun, Hyemin Lee, Adriana Heguy, Jae Yong Han, Jeremy S Dasen, Heebal Kim, Myungin Baek

eLife. 2022; 11: e78345. Published online 2022 Oct 26. doi: 10.7554/eLife.78345

PMCID:: PMC9605692

Abstract Article PDF–8.4M

Select item 88894377.

Thyroid hormone regulates glutamine metabolism and anaplerotic fluxes by inducing mitochondrial glutamate aminotransferase GPT2

Annunziata Gaetana Cicatiello, Serena Sagliocchi, Annarita Nappi, Emery Di Cicco, Caterina Miro, Melania Murolo, Mariano Stornaiuolo, Monica Dentice

Cell Rep. 2022 Feb 22; 38(8): 110409. Published online 2022 Feb 22. doi: 10.1016/j.celrep.2022.110409

Correction in:: Cell Rep. 2022 Mar 22; 38(12): 110562.

PMCID:: PMC8889437

Abstract Article

Select item 86777878.

Thyroid hormone receptor alpha sumoylation modulates white adipose tissue stores

Yan-Yun Liu, Jingjing Jiang, Sujie Ke, Anna Milanesi, Kiyomi Abe, Gilberto Gastelum, Jianrong Li, Gregory A. Brent

Sci Rep. 2021; 11: 24105. Published online 2021 Dec 16. doi: 10.1038/s41598-021-03491-6

PMCID:: PMC8677787

Abstract Article PDF–6.0M

Select item 84463389.

ACAA2 is a Ligand-dependent Coactivator for Thyroid Hormone Receptor β1

Wesley Wang, Dolena Ledee

Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Oct 22.

Published in final edited form as: Biochem Biophys Res Commun. 2021 Oct 22; 576: 15–21. Published online 2021 Aug 28. doi: 10.1016/j.bbrc.2021.08.073

PMCID:: PMC8446338

Abstract Article PDF–830K

Select item 842773510.

Thyroid Hormone Receptor α Regulates Autophagy, Mitochondrial Biogenesis, and Fatty Acid Use in Skeletal Muscle

Jin Zhou, Karine Gauthier, Jia Pei Ho, Andrea Lim, Xu-Guang Zhu, Cho Rong Han, Rohit Anthony Sinha, Sheue-Yann Cheng, Paul Michael Yen

Endocrinology. 2021 Sep; 162(9): bqab112. Published online 2021 Jun 4. doi: 10.1210/endocr/bqab112

PMCID:: PMC8427735

Abstract Article

Select item 834971411.

Thyroid Hormone Receptor α1 Mutants Impair B Lymphocyte Development in a Mouse Model

Sunmi Park, Xuguang Zhu, Minjun Kim, Li Zhao, Sheue-Yann Cheng

Thyroid. June 2021; 31(6): 994–1002. Published online 2021 Jun 8. doi: 10.1089/thy.2019.0782

PMCID:: PMC8349714

Abstract Article PDF–748K

Select item 831323912.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 826556613.

The Type 3 Deiodinase Is a Critical Modulator of Thyroid Hormone Sensitivity in the Fetal Brain

Maria Elena Martinez, Arturo Hernandez

Front Neurosci. 2021; 15: 703730. Published online 2021 Jun 29. doi: 10.3389/fnins.2021.703730

PMCID:: PMC8265566

Abstract Article PDF–8.3M

Select item 793877014.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 790728615.

Persistent COUP-TFII expression underlies the myopathy and impaired muscle regeneration observed in resistance to thyroid hormone-alpha

Paola Aguiari, Yan-Yun Liu, Astgik Petrosyan, Sheue-yann Cheng, Gregory A. Brent, Laura Perin, Anna Milanesi

Sci Rep. 2021; 11: 4601. Published online 2021 Feb 25. doi: 10.1038/s41598-021-84080-5

PMCID:: PMC7907286

Abstract Article PDF–7.3M

Select item 785228216.

Exacerbated age-related hearing loss in mice lacking the p43 mitochondrial T3 receptor

Corentin Affortit, François Casas, Sabine Ladrech, Jean-Charles Ceccato, Jérôme Bourien, Carolanne Coyat, Jean-Luc Puel, Marc Lenoir, Jing Wang

BMC Biol. 2021; 19: 18. Published online 2021 Feb 1. doi: 10.1186/s12915-021-00953-1

PMCID:: PMC7852282

Abstract Article PDF–5.4M

Select item 758297917.

Transient Changes of Metabolism at the Pronuclear Stage in Mice Influences Skeletal Muscle Phenotype in Adulthood

Christelle Bertrand-Gaday, Martine Letheule, Emilie Blanchet, Barbara Vernus, Laurence Pessemesse, Amélie Bonnet-Garnier, Anne Bonnieu, François Casas

Int J Mol Sci. 2020 Oct; 21(19): 7203. Published online 2020 Sep 29. doi: 10.3390/ijms21197203

PMCID:: PMC7582979

Abstract Article PDF–3.0M

Select item 741589018.

A Direct Comparison of Thyroid Hormone Receptor Protein Levels in Mice Provides Unexpected Insights into Thyroid Hormone Action

Svetlana Minakhina, Sanya Bansal, Alice Zhang, Michael Brotherton, Rucha Janodia, Vanessa De Oliveira, Srikanth Tadepalli, Fredric E. Wondisford

Thyroid. August 2020; 30(8): 1193–1204. Published online 2020 Aug 7. doi: 10.1089/thy.2019.0763

PMCID:: PMC7415890

Abstract Article PDF–667K

Select item 739585219.

In vitro and in vivo roles of glucocorticoid and vitamin D receptors in the control of neonatal cardiomyocyte proliferative potential

Stephen Cutie, Alexander Y. Payumo, Dominic Lunn, Guo N. Huang

J Mol Cell Cardiol. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: J Mol Cell Cardiol. 2020 May; 142: 126–134. Published online 2020 Apr 11. doi: 10.1016/j.yjmcc.2020.04.013

PMCID:: PMC7395852

Abstract Article PDF–2.1M

Select item 727447720.

Multiple mechanisms regulate H3 acetylation of enhancers in response to thyroid hormone

Stine M. Præstholm, Majken S. Siersbæk, Ronni Nielsen, Xuguang Zhu, Anthony N. Hollenberg, Sheue-yann Cheng, Lars Grøntved

PLoS Genet. 2020 May; 16(5): e1008770. Published online 2020 May 26. doi: 10.1371/journal.pgen.1008770

PMCID:: PMC7274477

Abstract Article PDF–3.6M

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