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Select item 81650301.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80459322.

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition

Yahya Benslimane, María Sánchez‐Osuna, Jasmin Coulombe‐Huntington, Thierry Bertomeu, Danielle Henry, Caroline Huard, Éric Bonneil, Pierre Thibault, Mike Tyers, Lea Harrington

Aging Cell. 2021 Apr; 20(4): e13331. Published online 2021 Mar 4. doi: 10.1111/acel.13331

PMCID:: PMC8045932

Abstract Article PDF–1.9M

Select item 78233643.

Lipid Profile of Activated Macrophages and Contribution of Group V Phospholipase A₂

Masaya Koganesawa, Munehiro Yamaguchi, Sachin K. Samuchiwal, Barbara Balestrieri

Biomolecules. 2021 Jan; 11(1): 25. Published online 2020 Dec 29. doi: 10.3390/biom11010025

PMCID:: PMC7823364

Abstract Article PDF–5.0M

Select item 72247014.

Degradation of Group V Secretory Phospholipase A₂ in Lung Endothelium is Mediated by Autophagy

Lucille N. Meliton, Xiangdong Zhu, Mary Brown, Yulia Epshtein, Takeshi Kawasaki, Eleftheria Letsiou, Steven M. Dudek

Microvasc Res. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: Microvasc Res. 2020 May; 129: 103954. Published online 2019 Nov 13. doi: 10.1016/j.mvr.2019.103954

PMCID:: PMC7224701

Abstract Article PDF–2.1M

Select item 42124095.

A Novel Genetic Approach to Investigate the Role of Plasma Secretory Phospholipase A2 (sPLA₂)-V Isoenzyme in Coronary Heart Disease: A Modified Mendelian Randomization Analysis Using PLA2G5 Expression Levels

Michael V. Holmes, Holly J. Exeter, Lasse Folkersen, Christopher P. Nelson, Montse Guardiola, Jackie A. Cooper, Reecha Sofat, S. Matthijs Boekholdt, Kay-Tee-Khaw, Ka-Wah Li, Andrew J. P. Smith, Ferdinand van’t Hooft, CARDIoGRAM, Per Eriksson, Anders Franco-Cereceda, Folkert W. Asselbergs, Jolanda M. A. Boer, N. Charlotte Onland-Moret, Marten Hofker, Jeanette Erdmann, Mika Kivimaki, Meena Kumari, Alex P. Reiner, Brendan J. Keating, Steve E. Humphries, Aroon D. Hingorani, Ziad Mallat, Nilesh J. Samani, Philippa J. Talmud

Circ Cardiovasc Genet. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Circ Cardiovasc Genet. 2014 Apr; 7(2): 144–150. Published online 2014 Feb 21. doi: 10.1161/CIRCGENETICS.113.000271

PMCID:: PMC4212409

Abstract Article PDF–562K

Select item 41634156.

The Step Further to Understand the Role of Cytosolic Phospholipase A₂ Alpha and Group X Secretory Phospholipase A₂ in Allergic Inflammation: Pilot Study

Ewa Pniewska, Milena Sokolowska, Izabela Kupryś-Lipińska, Monika Przybek, Piotr Kuna, Rafal Pawliczak

Biomed Res Int. 2014; 2014: 670814. Published online 2014 Aug 27. doi: 10.1155/2014/670814

PMCID:: PMC4163415

Abstract Article PDF–1.4M

Select item 40521567.

The (G>A) rs11573191 Polymorphism of PLA2G5 Gene Is Associated with Premature Coronary Artery Disease in the Mexican Mestizo Population: The Genetics of Atherosclerotic Disease Mexican Study

Gilberto Vargas-Alarcón, Carlos Posadas-Romero, Teresa Villarreal-Molina, Edith Alvarez-León, Javier Angeles-Martinez, María Elena Soto, Irma Monroy-Muñoz, Juan Gabriel Juárez, Carlos Jerges Sánchez-Ramírez, Julian Ramirez-Bello, Silvestre Ramírez-Fuentes, José Manuel Fragoso, José Manuel Rodríguez-Pérez

Biomed Res Int. 2014; 2014: 931361. Published online 2014 May 18. doi: 10.1155/2014/931361

PMCID:: PMC4052156

Abstract Article PDF–519K

Select item 39791388.

Endothelial protein C receptor-associated invasiveness of rheumatoid synovial fibroblasts is likely driven by group V secretory phospholipase A₂

Meilang Xue, Kaitlin Shen, Kelly McKelvey, Juan Li, Yee-Ka Agnes Chan, Vicky Hatzis, Lyn March, Christopher B Little, Michael Tonkin, Christopher J Jackson

Arthritis Res Ther. 2014; 16(1): R44. Published online 2014 Feb 5. doi: 10.1186/ar4473

PMCID:: PMC3979138

Abstract Article PDF–1.5M

Select item 39396999.

Group V secretory phospholipase A₂ is involved in macrophage activation and is sufficient for macrophage effector functions in allergic pulmonary inflammation

Shin Ohta, Mitsuru Imamura, Wei Xing, Joshua A. Boyce, Barbara Balestrieri

J Immunol. Author manuscript; available in PMC 2014 Jun 15.

Published in final edited form as: J Immunol. 2013 Jun 15; 190(12): 5927–5938. Published online 2013 May 6. doi: 10.4049/jimmunol.1203202

PMCID:: PMC3939699

Abstract Article PDF–1.7M

Select item 360634210.

Assessing Phospholipase A₂ Activity toward Cardiolipin by Mass Spectrometry

Yuan-Hao Hsu, Darren S. Dumlao, Jian Cao, Edward A. Dennis

PLoS One. 2013; 8(3): e59267. Published online 2013 Mar 22. doi: 10.1371/journal.pone.0059267

Correction in:: PLoS One. 2013; 8(6): 10.1371/annotation/47607b18-ed69-4a08-8619-60c39bd83a13.

PMCID:: PMC3606342

Abstract Article PDF–1002K

Select item 340187211.

Group V phospholipase A₂ increases pulmonary endothelial permeability through direct hydrolysis of the cell membrane

Nilda M. Muñoz, Anjali Desai, Lucille N. Meliton, Angelo Y. Meliton, Tingting Zhou, Alan R. Leff, Steven M. Dudek

Pulm Circ. 2012 Apr-Jun; 2(2): 182–192. doi: 10.4103/2045-8932.97604

PMCID:: PMC3401872

Abstract Article PDF–3.7M

Select item 323437512.

Biallelic Mutations in PLA2G5, Encoding Group V Phospholipase A₂, Cause Benign Fleck Retina

Panagiotis I. Sergouniotis, Alice E. Davidson, Donna S. Mackay, Eva Lenassi, Zheng Li, Anthony G. Robson, Xu Yang, Jaimie Hoh Kam, Timothy W. Isaacs, Graham E. Holder, Glen Jeffery, Jonathan A. Beck, Anthony T. Moore, Vincent Plagnol, Andrew R. Webster

Am J Hum Genet. 2011 Dec 9; 89(6): 782–791. doi: 10.1016/j.ajhg.2011.11.004

PMCID:: PMC3234375

Abstract Article PDF–1.2M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 309593714.

Group V Phospholipase A₂ Mediates Barrier Disruption of Human Pulmonary Endothelial Cells Caused by LPS In Vitro

Steven M. Dudek, Nilda M. Muñoz, Anjali Desai, Christopher M. Osan, Angelo Y. Meliton, Alan R. Leff

Am J Respir Cell Mol Biol. 2011 Mar; 44(3): 361–368. Published online 2010 May 6. doi: 10.1165/rcmb.2009-0446OC

PMCID:: PMC3095937

Abstract Article PDF–1.8M

Select item 305861415.

A novel anti-inflammatory role for secretory phospholipase A₂ in immune complex-mediated arthritis

Eric Boilard, Ying Lai, Katherine Larabee, Barbara Balestrieri, Farideh Ghomashchi, Daisuke Fujioka, Reuben Gobezie, Jonathan S Coblyn, Michael E Weinblatt, Elena M Massarotti, Thomas S Thornhill, Maziar Divangahi, Heinz Remold, Gérard Lambeau, Michael H Gelb, Jonathan P Arm, David M Lee

EMBO Mol Med. 2010 May; 2(5): 172–187. doi: 10.1002/emmm.201000072

PMCID:: PMC3058614

Abstract Article PDF–874K

Select item 294516816.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 277583217.

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani

Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014

PMCID:: PMC2775832

Abstract Article PDF–2.8M

Select item 157291518.

VEGF stimulation of endothelial cell PAF synthesis is mediated by group V 14 kDa secretory phospholipase A₂

Pascal N Bernatchez, Michelle V Winstead, Edward A Dennis, Martin G Sirois

Br J Pharmacol. 2001 Sep; 134(1): 197–205. doi: 10.1038/sj.bjp.0704215

PMCID:: PMC1572915

Abstract Article PDF–233K

Select item 138366819.

Group V and X secretory phospholipase A₂ prevents adenoviral infection in mammalian cells

Michiko Mitsuishi, Seiko Masuda, Ichiro Kudo, Makoto Murakami

Biochem J. 2006 Jan 1; 393(Pt 1): 97–106. Prepublished online 2005 Sep 8. Published online 2005 Dec 12. doi: 10.1042/BJ20050781

PMCID:: PMC1383668

Abstract Article PDF–802K

Select item 122110820.

The molecular basis of phosphatidylcholine preference of human group-V phospholipase A2.

K P Kim, S K Han, M Hong, W Cho

Biochem J. 2000 Jun 15; 348(Pt 3): 643–647.

PMCID:: PMC1221108

Summary PDF–151K

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